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$118+ Cheap flights from Iowa to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SFO
ago 7 — ago 141
gio 8/7
gio 8/14
1 adult, Economy
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Cheap flight deals from Iowa to San Francisco

Keep the following information in mind while searching for Iowa to San Francisco flight deals. Data was last updated agosto 2, 2025.

Round-trip from

$218
(Frontier)

One-way from

$115
(Frontier)

Popular in

July

Cheapest in

August

Average price

$377
From Iowa to San Francisco
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One-way flight from Iowa to San Francisco
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Iowa to San Francisco

Cheapest flights from Iowa to San Francisco
Explore the most affordable flight options available from Iowa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 2, 2025.

This Frontier deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 10/153:30 pmDSM - SFO
1 stop8h 57mFrontier
mer 10/226:00 amSFO - DSM
1 stop6h 43mFrontier
Deal found 8/1$218
This FlightHub deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 8/1011:10 amOMA - SFO
1 stop25h 15mFrontier
mer 8/138:53 pmSFO - OMA
1 stop11h 23mFrontier
Deal found 7/31$235
This Alaska Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 10/253:05 pmOMA - SFO
1 stop9h 24mAlaska Airlines
lun 10/277:37 pmSFO - OMA
1 stop16h 32mAlaska Airlines
Deal found 8/1$236
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 9/156:00 pmOMA - SFO
1 stop7h 50mDelta
mar 9/1612:45 amSFO - OMA
1 stop7h 27mDelta
Deal found 8/1$237
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 8/287:30 amOMA - SFO
Nonstop3h 42mUnited Airlines
gio 9/44:55 pmSFO - OMA
Nonstop3h 18mUnited Airlines
Deal found 7/31$249
This Frontier deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 8/298:22 pmCID - SFO
1 stop5h 57mFrontier
dom 8/316:26 amSFO - CID
1 stop11h 11mFrontier
Deal found 8/1$258
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 8/266:10 amOMA - SFO
1 stop7h 10mSouthwest
ven 8/295:15 amSFO - OMA
1 stop7h 00mSouthwest
Deal found 8/1$283
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 8/214:59 pmMLI - SFO
1 stop7h 50mDelta
mer 9/36:15 amSFO - MLI
1 stop8h 04mDelta
Deal found 7/31$289
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 9/137:00 amCID - SFO
1 stop8h 45mDelta
ven 9/1912:45 amSFO - CID
1 stop8h 45mDelta
Deal found 7/31$289
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 8/2110:42 amMLI - SFO
2 stops10h 12mAmerican Airlines
mar 9/212:47 amSFO - MLI
1 stop8h 03mAmerican Airlines
Deal found 7/31$294
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 8/232:57 pmCID - SFO
1 stop8h 36mAmerican Airlines
sab 8/2312:45 amSFO - CID
1 stop6h 28mAmerican Airlines
Deal found 8/2$308
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 8/157:28 pmOMA - SFO
1 stop5h 39mAmerican Airlines
dom 8/1712:45 amSFO - OMA
1 stop8h 26mAmerican Airlines
Deal found 8/1$309

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 2, 2025.
Use the filters below to find and compare flights from Iowa to San Francisco that are best for you.

Fly from

Iowa

Fly to

San Francisco

Route

Depart

Return

Price

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

mer 10/15

3:30 pm-10:27 pm

1 stop8h 57m

San Francisco

mer 10/22

6:00 am-2:43 pm

1 stop6h 43m

$218

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

sab 10/25

3:05 pm-10:29 pm

1 stop9h 24m

San Francisco

lun 10/27

7:37 pm-2:09 pm

1 stop16h 32m

$236

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

lun 9/15

6:00 pm-11:50 pm

1 stop7h 50m

San Francisco

mar 9/16

12:45 am-10:12 am

1 stop7h 27m

$237

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

ven 8/29

8:45 pm-12:19 am

1 stop5h 34m

San Francisco

lun 9/1

6:26 am-7:50 pm

1 stop11h 24m

$238

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

gio 8/28

7:30 am-9:12 am

Nonstop3h 42m

San Francisco

gio 9/4

4:55 pm-10:13 pm

Nonstop3h 18m

$249

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

ven 8/29

8:22 pm-12:19 am

1 stop5h 57m

San Francisco

dom 8/31

6:26 am-7:37 pm

1 stop11h 11m

$258

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

mer 10/8

7:55 pm-11:05 pm

1 stop5h 10m

San Francisco

ven 10/10

4:50 pm-11:55 pm

1 stop5h 05m

$269

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

gio 8/21

4:59 pm-10:49 pm

1 stop7h 50m

San Francisco

mer 9/3

6:15 am-4:19 pm

1 stop8h 04m

$289

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

sab 9/13

7:00 am-1:45 pm

1 stop8h 45m

San Francisco

ven 9/19

12:45 am-11:30 am

1 stop8h 45m

$289

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

gio 8/21

10:42 am-6:54 pm

2 stops10h 12m

San Francisco

mar 9/2

12:47 am-10:50 am

1 stop8h 03m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 45 results
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Best time to book a flight from Iowa to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Francisco

What is the cheapest month to book a flight from Iowa to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Iowa to San Francisco (average of $276). Flying from Iowa to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SFO?

Find hourly flight availability from Iowa to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 2, 2025.

When flying from Iowa to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated agosto 2, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest, and Delta from Iowa to San Francisco by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,246 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,983 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,904 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Iowa to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Iowa?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Iowa to San Francisco.

  • What are the cheapest airlines to fly from Iowa to San Francisco one-way?

    $115 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Alaska Airlines and Delta, with prices starting from $118 and $119, respectively.

  • What are the most popular routes from Iowa to San Francisco?

    The most popular route from Iowa to San Francisco is Omaha Eppley Airfield - San Francisco. You may also consider Cedar Rapids - San Francisco or Des Moines - San Francisco.

  • Can I find deals for flights from Iowa to San Francisco that include hotel bookings?

    Yes. In addition to deals on Iowa to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Francisco.

  • Can I find deals for business class flights from Iowa to San Francisco?

    Yes. Cheapflights offers flight deals from Iowa to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Iowa to San Francisco (average of $276). Flying from Iowa to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
South San Francisco
Livermore
Turlock
Manteca
Antioch
Hollister
Watsonville
Sunnyvale
Newark
Milpitas
Campbell
Foster City
Capitola
Santa Clara
San Leandro
Burlingame
Redwood City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Iowa to San Francisco

Discover the top 5 airlines that operate flights from Iowa to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$215FlexibilityNo cancel feeOn-time62%
DeltaCheapest$265Average$397FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$473FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$420FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$356Average$432FlexibilityNo cancel feeOn-time63%

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