How long is the flight from Iowa to San Francisco?

A quick flight from Iowa to San Francisco can take about 5h 30m. Southwest provides one of the quickest options available for as low as $167. There are 1429 mi between Iowa and San Francisco. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What are the most popular routes from Iowa to San Francisco?

The most popular route from Iowa to San Francisco is Omaha Eppley Airfield - San Francisco. You may also consider Des Moines - San Francisco or Cedar Rapids - San Francisco.

What are the most popular airlines that fly from Iowa to San Francisco?

The most popular airlines flying from Iowa to San Francisco are American Airlines, Delta and Frontier. Something to consider prior to booking your flight.

What airport do you fly into for flights to San Francisco from Iowa?

San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Iowa to San Francisco.

Can I find deals for flights from Iowa to San Francisco that include hotel bookings?

Yes. In addition to deals on Iowa to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Iowa to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Francisco.

Can I find deals for business class flights from Iowa to San Francisco?

Yes. Cheapflights offers flight deals from Iowa to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$82+ Flights from Iowa to San Francisco

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Iowa to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to San Francisco

Round-trip from	$149 (CheapOair)
One-way from	$82 (Trip.com)
Popular in	March
Cheapest in	September
Average price	$366

From Iowa to San Francisco

Search Deals

One-way flight from Iowa to San Francisco

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($34 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Find flight deals from Iowa to San Francisco

Cheapest flights from Iowa to San Francisco
Explore the most affordable flight options available from Iowa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Fri 11/72:32 pmDSM - SFO

1 stop11h 42mFrontier

Mon 11/106:34 amSFO - DSM

1 stop5h 13mFrontier

Deal found 9/15

$149

Fri 11/78:51 pmOMA - SFO

1 stop5h 23mFrontier

Mon 11/106:34 amSFO - OMA

1 stop11h 32mFrontier

Deal found 9/14

$159

Fri 11/78:26 pmCID - SFO

1 stop5h 48mFrontier

Mon 11/106:34 amSFO - CID

1 stop11h 02mFrontier

Deal found 9/15

$159

Sat 10/255:05 pmOMA - SFO

1 stop5h 40mSouthwest

Tue 10/282:20 pmSFO - OMA

1 stop5h 45mSouthwest

Deal found 9/15

$167

Thu 10/22:25 pmDSM - SFO

1 stop11h 51mFrontier

Mon 10/66:29 amSFO - DSM

1 stop5h 11mFrontier

Deal found 9/14

$172

Thu 9/257:48 pmOMA - SFO

1 stop6h 28mFrontier

Thu 10/26:29 amSFO - OMA

1 stop10h 15mFrontier

Deal found 9/14

$177

Mon 11/38:51 pmOMA - SFO

1 stop5h 23mFrontier

Thu 11/66:34 amSFO - OMA

1 stop10h 17mFrontier

Deal found 9/16

$182

Fri 10/248:10 pmOMA - SFO

1 stop5h 35mSouthwest

Tue 10/282:20 pmSFO - OMA

1 stop5h 45mSouthwest

Deal found 9/15

$183

Thu 10/238:59 pmOMA - SFO

1 stop19h 23mFrontier

Sun 10/268:21 pmSFO - OMA

1 stop21h 43mFrontier

Deal found 9/14

$184

Mon 10/208:59 pmOMA - SFO

1 stop27h 28mFrontier

Fri 10/248:21 pmSFO - OMA

1 stop21h 43mFrontier

Deal found 9/15

$185

Fri 10/38:35 pmOMA - SFO

1 stop5h 41mFrontier

Mon 10/66:29 amSFO - OMA

1 stop4h 52mFrontier

Deal found 9/16

$187

Wed 10/152:37 pmDSM - SFO

1 stop9h 50mFrontier

Wed 10/299:55 pmSFO - DSM

2 stops13h 52mFrontier

Deal found 9/15

$189

Best flights from Iowa to San Francisco
Discover carefully curated flight deals from Iowa to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2025.

Wed 12/36:40 amOMA - SFO

1 stop5h 30mSouthwest

Sat 12/66:25 amSFO - OMA

1 stop8h 05mSouthwest

Deal found 9/15

$167

Thu 10/302:32 pmDSM - SFO

1 stop11h 42mFrontier

Thu 11/66:34 amSFO - DSM

1 stop5h 13mFrontier

Deal found 9/15

$192

Mon 3/23:05 pmOMA - SFO

1 stop9h 13mHawaiian Airlines

Wed 3/46:00 amSFO - OMA

1 stop6h 12mHawaiian Airlines

Deal found 9/15

$236

Sat 11/18:30 amOMA - SFO

1 stop5h 50mDelta

Fri 11/712:35 amSFO - OMA

1 stop7h 39mDelta

Deal found 9/14

$237

Tue 10/146:00 amOMA - SFO

1 stop8h 19mUnited Airlines

Sat 10/184:30 pmSFO - OMA

Nonstop3h 30mUnited Airlines

Deal found 9/15

$253

Wed 10/152:37 pmCID - SFO

1 stop7h 34mAmerican Airlines

Wed 10/226:10 amSFO - CID

1 stop6h 10mAmerican Airlines

Deal found 9/16

$289

Wed 10/299:30 amDSM - SFO

2 stops31h 02mMultiple Airlines

Wed 11/56:34 amSFO - DSM

1 stop29h 13mMultiple Airlines

Deal found 9/14

$318

Fri 10/248:10 pmOMA - SFO

1 stop5h 35mSouthwest

Tue 10/282:20 pmSFO - OMA

1 stop5h 45mSouthwest

Deal found 9/15

$183

Mon 10/68:16 pmCID - SFO

1 stop6h 00mFrontier

Mon 10/136:34 amSFO - CID

1 stop10h 52mFrontier

Deal found 9/14

$211

Fri 10/38:16 pmCID - SFO

1 stop6h 00mFrontier

Sun 10/56:29 amSFO - CID

1 stop11h 02mFrontier

Deal found 9/16

$211

Mon 2/165:50 amOMA - SFO

1 stop6h 05mSouthwest

Mon 2/237:35 amSFO - OMA

1 stop5h 45mSouthwest

Deal found 9/15

$234

Thu 11/132:32 pmDSM - SFO

1 stop26h 08mFrontier

Mon 11/176:34 amSFO - DSM

1 stop5h 13mFrontier

Deal found 9/13

$214

Fri 11/142:34 pmDSM - SFO

1 stop11h 40mFrontier

Mon 11/176:34 amSFO - DSM

1 stop5h 13mFrontier

Deal found 9/15

$214

Sat 1/173:45 pmMLI - SFO

1 stop7h 45mUnited Airlines

Sat 1/2411:15 pmSFO - MLI

1 stop8h 57mUnited Airlines

Deal found 9/13

$289

Tue 12/1611:29 amCID - SFO

2 stops9h 33mAmerican Airlines

Thu 1/89:29 amSFO - CID

1 stop10h 12mAmerican Airlines

Deal found 9/14

$294

Thu 10/212:55 pmOMA - SFO

1 stop5h 20mSouthwest

Tue 10/75:30 amSFO - OMA

2 stops8h 25mSouthwest

Deal found 9/15

$243

Thu 3/125:42 pmMLI - SFO

1 stop8h 27mUnited Airlines

Tue 3/176:30 amSFO - MLI

1 stop6h 35mUnited Airlines

Deal found 9/15

$289

Fri 10/35:57 amCID - SFO

1 stop10h 29mDelta

Mon 10/69:50 pmSFO - CID

2 stops11h 55mDelta

Deal found 9/15

$319

Thu 9/252:25 pmDSM - SFO

1 stop11h 51mFrontier

Mon 9/296:29 amSFO - DSM

1 stop5h 11mFrontier

Deal found 9/14

$229

Mon 12/227:28 pmCID - SFO

1 stop7h 04mAmerican Airlines

Wed 1/71:22 pmSFO - CID

1 stop6h 12mAmerican Airlines

Deal found 9/14

$314

Fri 9/262:25 pmDSM - SFO

1 stop11h 51mFrontier

Sun 9/286:29 amSFO - DSM

1 stop5h 11mFrontier

Deal found 9/15

$230

Mon 12/227:28 pmCID - SFO

1 stop7h 04mAmerican Airlines

Fri 1/95:29 amSFO - CID

1 stop7h 33mAmerican Airlines

Deal found 9/14

$314

Mon 9/298:16 pmCID - SFO

1 stop6h 00mFrontier

Fri 10/36:29 amSFO - CID

1 stop11h 02mFrontier

Deal found 9/14

$230

Tue 9/306:45 pmMLI - SFO

1 stop7h 14mUnited Airlines

Mon 10/65:15 amSFO - MLI

1 stop9h 39mUnited Airlines

Deal found 9/16

$339

Thu 10/25:34 pmCID - SFO

1 stop7h 54mAmerican Airlines

Sun 10/512:50 amSFO - CID

1 stop6h 24mAmerican Airlines

Deal found 9/16

$314

Thu 10/28:16 pmCID - SFO

1 stop6h 00mFrontier

Sun 10/56:29 amSFO - CID

1 stop11h 02mFrontier

Deal found 9/16

$238

Sat 11/16:46 pmSUX - SFO

1 stop6h 09mUnited Airlines

Wed 11/58:30 amSFO - SUX

1 stop7h 38mUnited Airlines

Deal found 9/14

$359

Thu 2/1911:16 amMLI - SFO

1 stop9h 21mAmerican Airlines

Sun 2/2211:35 pmSFO - MLI

1 stop9h 05mAmerican Airlines

Deal found 9/16

$334

Tue 9/306:00 amALO - SFO

1 stop8h 31mAmerican Airlines

Sat 10/41:21 pmSFO - ALO

1 stop6h 44mAmerican Airlines

Deal found 9/14

$339

Fri 10/312:32 pmDSM - SFO

1 stop11h 42mFrontier

Fri 11/76:34 amSFO - DSM

1 stop5h 13mFrontier

Deal found 9/15

$257

Last-minute flights from Iowa to San Francisco
Discover last-minute flight deals from Iowa to San Francisco. Data last updated September 16, 2025 and is based on user searches.

Thu 9/257:48 pmOMA - SFO

1 stop6h 28mFrontier

Thu 10/26:29 amSFO - OMA

1 stop10h 15mFrontier

Deal found 9/14

$177

Mon 9/292:16 pmOMA - SFO

1 stop12h 00mFrontier

Thu 10/26:29 amSFO - OMA

1 stop10h 15mFrontier

Deal found 9/14

$192

Thu 10/22:25 pmDSM - SFO

1 stop11h 51mFrontier

Mon 10/66:29 amSFO - DSM

1 stop5h 11mFrontier

Deal found 9/14

$172

Fri 10/38:35 pmOMA - SFO

1 stop5h 41mFrontier

Mon 10/66:29 amSFO - OMA

1 stop4h 52mFrontier

Deal found 9/16

$187

Fri 10/38:16 pmCID - SFO

1 stop6h 00mFrontier

Mon 10/66:29 amSFO - CID

1 stop11h 02mFrontier

Deal found 9/15

$193

Wed 10/152:37 pmDSM - SFO

1 stop9h 50mFrontier

Wed 10/299:55 pmSFO - DSM

2 stops13h 52mFrontier

Deal found 9/15

$189

Thu 10/168:59 pmOMA - SFO

1 stop5h 15mFrontier

Mon 10/206:34 amSFO - OMA

1 stop11h 30mFrontier

Deal found 9/14

$195

Mon 10/208:59 pmOMA - SFO

1 stop27h 28mFrontier

Fri 10/248:21 pmSFO - OMA

1 stop21h 43mFrontier

Deal found 9/15

$185

Thu 10/238:59 pmOMA - SFO

1 stop19h 23mFrontier

Sun 10/268:21 pmSFO - OMA

1 stop21h 43mFrontier

Deal found 9/14

$184

Fri 10/248:10 pmOMA - SFO

1 stop5h 35mSouthwest

Tue 10/282:20 pmSFO - OMA

1 stop5h 45mSouthwest

Deal found 9/15

$183

Sat 10/255:05 pmOMA - SFO

1 stop5h 40mSouthwest

Tue 10/282:20 pmSFO - OMA

1 stop5h 45mSouthwest

Deal found 9/15

$167

Thu 10/302:32 pmDSM - SFO

1 stop11h 42mFrontier

Thu 11/66:34 amSFO - DSM

1 stop5h 13mFrontier

Deal found 9/15

$192

One-way flights from Iowa to San Francisco
Search for one-way flight options from Iowa to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 16, 2025.

Sun 12/78:47 pmOMA - SFO

1 stop24h 08mFrontier

Deal found 9/14

$82

Wed 10/2212:25 pmOMA - SFO

1 stop6h 40mSouthwest

Deal found 9/15

$84

Tue 10/287:00 amOMA - SFO

2 stops9h 10mSouthwest

Deal found 9/15

$89

Fri 10/318:51 pmOMA - SFO

1 stop27h 36mFrontier

Deal found 9/15

$91

Wed 10/87:30 amDSM - SFO

1 stop15h 52mMultiple Airlines

Deal found 9/13

$98

Sun 11/96:05 amOMA - SFO

1 stop5h 25mSouthwest

Deal found 9/14

$100

Fri 10/311:20 pmOMA - SFO

2 stops10h 05mSouthwest

Deal found 9/15

$105

Wed 11/510:55 amOMA - SFO

1 stop8h 29mDelta

Deal found 9/15

$119

Sun 11/97:46 pmOMA - SFO

2 stops30h 23mFrontier

Deal found 9/14

$121

Fri 10/178:59 pmOMA - SFO

1 stop27h 30mFrontier

Deal found 9/15

$123

Wed 10/82:37 pmDSM - SFO

2 stops28h 43mFrontier

Deal found 9/13

$123

Thu 11/62:32 pmDSM - SFO

2 stops35h 37mFrontier

Deal found 9/14

$124

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

Wed 12/3

6:40 am-10:10 am

1 stop5h 30m

San Francisco

Sat 12/6

6:25 am-4:30 pm

1 stop8h 05m

$167

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

Fri 10/24

8:10 pm-11:45 pm

1 stop5h 35m

San Francisco

Tue 10/28

2:20 pm-10:05 pm

1 stop5h 45m

$183

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

Thu 10/30

2:32 pm-12:14 am

1 stop11h 42m

San Francisco

Thu 11/6

6:34 am-1:47 pm

1 stop5h 13m

$192

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

Mon 10/6

8:16 pm-12:16 am

1 stop6h 00m

San Francisco

Mon 10/13

6:34 am-7:26 pm

1 stop10h 52m

$211

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

Fri 10/3

8:16 pm-12:16 am

1 stop6h 00m

San Francisco

Sun 10/5

6:29 am-7:31 pm

1 stop11h 02m

$211

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

Thu 11/13

2:32 pm-2:40 pm

1 stop26h 08m

San Francisco

Mon 11/17

6:34 am-1:47 pm

1 stop5h 13m

$214

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

Fri 11/14

2:34 pm-12:14 am

1 stop11h 40m

San Francisco

Mon 11/17

6:34 am-1:47 pm

1 stop5h 13m

$214

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

Thu 9/25

2:25 pm-12:16 am

1 stop11h 51m

San Francisco

Mon 9/29

6:29 am-1:40 pm

1 stop5h 11m

$229

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

Fri 9/26

2:25 pm-12:16 am

1 stop11h 51m

San Francisco

Sun 9/28

6:29 am-1:40 pm

1 stop5h 11m

$230

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

Mon 9/29

8:16 pm-12:16 am

1 stop6h 00m

San Francisco

Fri 10/3

6:29 am-7:31 pm

1 stop11h 02m

$230

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results

...

Best time to book a flight from Iowa to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Iowa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Francisco

What is the cheapest month to book a flight from Iowa to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Iowa to San Francisco (average of $276). Flying from Iowa to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SFO?

When flying from Iowa to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

What airport do you fly into for flights to San Francisco from Iowa?
San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Iowa to San Francisco.
How long is the flight from Iowa to San Francisco?
A quick flight from Iowa to San Francisco can take about 5h 30m. Southwest provides one of the quickest options available for as low as $167. There are 1429 mi between Iowa and San Francisco. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the most popular routes from Iowa to San Francisco?
The most popular route from Iowa to San Francisco is Omaha Eppley Airfield - San Francisco. You may also consider Des Moines - San Francisco or Cedar Rapids - San Francisco.
Can I find deals for flights from Iowa to San Francisco that include hotel bookings?
Yes. In addition to deals on Iowa to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Iowa to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Francisco.
Can I find deals for business class flights from Iowa to San Francisco?
Yes. Cheapflights offers flight deals from Iowa to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Iowa to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Iowa to San Francisco (average of $276). Flying from Iowa to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Santa Cruz

Livermore

South San Francisco

Turlock

Antioch

Watsonville

Santa Clara

Manteca

Sunnyvale

Hollister

Vacaville

Foster City

Union City

Vallejo

Burlingame

Redwood City

San Mateo

San Leandro

Lathrop

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Iowa to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$108	Average$230	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$265	Average$382	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$288	Average$483	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$288	Average$439	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$344	Average$425	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$82+ Cheap flights from Iowa to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Iowa to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Iowa to San Francisco

Keep the following information in mind while searching for Iowa to San Francisco flight deals. Data was last updated September 16, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Iowa to San Francisco

Cheapest flights from Iowa to San FranciscoExplore the most affordable flight options available from Iowa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Explore the most affordable flight options available from Iowa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to San Francisco that are best for you.

Best time to book a flight from Iowa to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Iowa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Francisco

What is the cheapest month to book a flight from Iowa to San Francisco?

What is the cheapest time of day to fly from IA to SFO?

Find hourly flight availability from Iowa to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Related info for your journey

Find useful and relevant information for your journey from Iowa to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to San Francisco from Iowa?

How long is the flight from Iowa to San Francisco?

What are the most popular routes from Iowa to San Francisco?

Can I find deals for flights from Iowa to San Francisco that include hotel bookings?

How can I find direct flights from Iowa to San Francisco?

Can I find deals for business class flights from Iowa to San Francisco?

What is the cheapest month to book a flight from Iowa to San Francisco?

Traveling to a place near San Francisco?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Iowa to San Francisco

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Iowa to San Francisco
Explore the most affordable flight options available from Iowa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.