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$119+ Cheap flights from Iowa to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SFO
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Iowa to San Francisco

Keep the following information in mind while searching for Iowa to San Francisco flight deals. Data was last updated junio 12, 2025.

Round-trip from

$259
(American Airlines)

One-way from

$119
(Delta)

Popular in

March

Cheapest in

September

Average price

$438
From Iowa to San Francisco
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One-way flight from Iowa to San Francisco
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Highest demand for flights based on searches. 6% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Iowa to San Francisco

Cheapest flights from Iowa to San Francisco
Explore the most affordable flight options available from Iowa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/208:04 amOMA - SFO
1 stop7h 26mDelta
mié. 8/2011:59 pmSFO - OMA
1 stop8h 03mDelta
Deal found 6/12$258
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/176:30 pmOMA - SFO
1 stop7h 12mAmerican Airlines
dom. 7/2012:55 amSFO - OMA
1 stop6h 09mAmerican Airlines
Deal found 6/12$259
This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/147:33 pmDSM - SFO
1 stop6h 46mFrontier
vie. 7/186:37 amSFO - DSM
1 stop10h 11mFrontier
Deal found 6/9$260
This Frontier deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/177:51 pmOMA - SFO
1 stop6h 28mFrontier
dom. 8/246:26 amSFO - OMA
1 stop11h 24mFrontier
Deal found 6/12$261
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/268:10 pmOMA - SFO
1 stop5h 35mSouthwest
vie. 8/13:00 pmSFO - OMA
1 stop6h 00mSouthwest
Deal found 6/10$269
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/116:57 amOMA - SFO
Nonstop3h 48mUnited Airlines
vie. 7/184:10 pmSFO - OMA
Nonstop3h 31mUnited Airlines
Deal found 6/11$273
This Frontier deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/167:16 pmCID - SFO
1 stop6h 09mFrontier
jue. 8/216:26 amSFO - CID
1 stop11h 11mFrontier
Deal found 6/12$278
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/104:22 pmMLI - SFO
1 stop8h 25mAmerican Airlines
mar. 7/155:41 amSFO - MLI
1 stop7h 43mAmerican Airlines
Deal found 6/12$289
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/127:00 amCID - SFO
1 stop8h 28mDelta
mar. 8/1911:35 amSFO - CID
1 stop9h 20mDelta
Deal found 6/10$289
This Alaska Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/163:14 pmOMA - SFO
1 stop7h 58mAlaska Airlines
mar. 8/2610:54 amSFO - OMA
2 stops11h 05mAlaska Airlines
Deal found 6/12$292
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/46:09 pmDSM - SFO
1 stop7h 00mAmerican Airlines
mar. 9/912:47 amSFO - DSM
1 stop6h 52mAmerican Airlines
Deal found 6/11$297
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/276:53 pmSUX - SFO
1 stop6h 17mUnited Airlines
mar. 7/18:35 amSFO - SUX
1 stop7h 43mUnited Airlines
Deal found 6/12$304

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Iowa to San Francisco that are best for you.

Fly from

Iowa

Fly to

San Francisco

Route

Depart

Return

Price

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

mié. 8/20

8:04 am-1:30 pm

1 stop7h 26m

San Francisco

mié. 8/20

11:59 pm-10:02 am

1 stop8h 03m

$258

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

jue. 7/17

6:30 pm-11:42 pm

1 stop7h 12m

San Francisco

dom. 7/20

12:55 am-9:04 am

1 stop6h 09m

$259

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

lun. 7/14

7:33 pm-12:19 am

1 stop6h 46m

San Francisco

vie. 7/18

6:37 am-6:48 pm

1 stop10h 11m

$260

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

dom. 8/17

7:51 pm-12:19 am

1 stop6h 28m

San Francisco

dom. 8/24

6:26 am-7:50 pm

1 stop11h 24m

$261

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

sáb. 7/26

8:10 pm-11:45 pm

1 stop5h 35m

San Francisco

vie. 8/1

3:00 pm-11:00 pm

1 stop6h 00m

$269

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

vie. 7/11

6:57 am-8:45 am

Nonstop3h 48m

San Francisco

vie. 7/18

4:10 pm-9:41 pm

Nonstop3h 31m

$273

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

sáb. 8/16

7:16 pm-11:25 pm

1 stop6h 09m

San Francisco

jue. 8/21

6:26 am-7:37 pm

1 stop11h 11m

$278

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

jue. 7/10

4:22 pm-10:47 pm

1 stop8h 25m

San Francisco

mar. 7/15

5:41 am-3:24 pm

1 stop7h 43m

$289

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

mar. 8/12

7:00 am-1:28 pm

1 stop8h 28m

San Francisco

mar. 8/19

11:35 am-10:55 pm

1 stop9h 20m

$289

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

sáb. 8/16

3:14 pm-9:12 pm

1 stop7h 58m

San Francisco

mar. 8/26

10:54 am-11:59 pm

2 stops11h 05m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 48 results
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Best time to book a flight from Iowa to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Francisco

What is the cheapest month to book a flight from Iowa to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Iowa to San Francisco (average of $276). Flying from Iowa to San Francisco in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SFO?

Find hourly flight availability from Iowa to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Iowa to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated junio 12, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Iowa to San Francisco to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Iowa to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Iowa?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Iowa to San Francisco.

  • What are the cheapest airlines to fly from Iowa to San Francisco one-way?

    $119 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Frontier and American Airlines, with prices starting from $129 and $130, respectively.

  • What are the most popular routes from Iowa to San Francisco?

    The most popular route from Iowa to San Francisco is Omaha Eppley Airfield - San Francisco. You may also consider Des Moines - San Francisco or Cedar Rapids - San Francisco.

  • Can I find deals for flights from Iowa to San Francisco that include hotel bookings?

    Yes. In addition to deals on Iowa to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Francisco.

  • Can I find deals for business class flights from Iowa to San Francisco?

    Yes. Cheapflights offers flight deals from Iowa to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Iowa to San Francisco (average of $276). Flying from Iowa to San Francisco in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
Roseville
Mountain View
South San Francisco
Livermore
Turlock
Santa Cruz
Manteca
Fairfield
Watsonville
Antioch
Hollister
Milpitas
Newark
Hayward
Alameda
Sunnyvale
Daly City
Union City
Campbell
Capitola

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Alternative routes for Iowa to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Iowa to San Francisco

Discover the top 5 airlines that operate flights from Iowa to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$210FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$286Average$424FlexibilityNo cancel feeOn-time71%
DeltaCheapest$288Average$409FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$464FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$356Average$434FlexibilityNo cancel feeOn-time63%

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