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$475+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SFO
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Find flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:47 pmPGV - SFO
1 stop9h 09mAmerican Airlines
Tue 11/411:59 pmSFO - PGV
1 stop9h 03mAmerican Airlines
Deal found 10/16$502
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:00 amPGV - SFO
1 stop10h 38mAmerican Airlines
Wed 11/127:15 amSFO - PGV
1 stop8h 36mAmerican Airlines
Deal found 10/16$513

Cheap flight deals from Greenville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$502
(American Airlines)

One-way from

$475
(American Airlines)
Provider with most accurate pricing for Pitt-Greenville-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Pitt-Greenville-San Francisco flights.
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From Pitt-Greenville to San Francisco
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One-way flight from Pitt-Greenville to San Francisco
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Greenville

Fly to

San Francisco

Route

Depart

Return

Price

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Wed 11/5

6:00 am-1:29 pm

2 stops10h 29m

San Francisco

Wed 11/12

7:15 am-6:51 pm

1 stop8h 36m

$502

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Fri 10/31

3:47 pm-9:56 pm

1 stop9h 09m

San Francisco

Tue 11/4

11:59 pm-12:02 pm

1 stop9h 03m

$502

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Tue 3/10

5:12 am-8:58 pm

2 stops18h 46m

San Francisco

Wed 3/11

10:10 am-10:22 am

2 stops21h 12m

$794

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Wed 3/11

11:00 am-5:16 pm

1 stop9h 16m

$475

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

  • Most accurate provider: When it comes to deals on Greenville, North Carolina-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville, North Carolina-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville, North Carolina-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville, North Carolina-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville, North Carolina-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

Currently, April is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $147). Flying from Greenville, North Carolina to San Francisco in October is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 16, 2025.
Peruse reviews from past customers who have flown with American Airlines from Greenville to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,043 reviews

Boarding

7.5

Comfort

7.2

Overall

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Reviews

1 / 20
8.0
Excellent

Aaron,Sep 2023

CLT - ORD

The extra cost of first class was not worth it.
American Airlines
7.2
Good
11,043 reviews
American Airlines
7.2
Good
11,043 reviews

Boarding

7.5

Comfort

7.2

Overall

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Reviews

1 / 20
8.0
Excellent

Aaron,Sep 2023

CLT - ORD

The extra cost of first class was not worth it.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville, North Carolina to San Francisco?

    A quick flight from Greenville, North Carolina to San Francisco can take about 10h 29m. American Airlines provides one of the quickest options available for as low as $502. There are 2473 mi between Greenville, North Carolina and San Francisco.

  • What is the cheapest airline to fly from Greenville, North Carolina to San Francisco round-trip?

    Currently priced at $248, American Airlines will fly you from Greenville, North Carolina to San Francisco and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

  • Can I find deals for business class flights from Greenville to San Francisco?

    Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

    Currently, April is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $147). Flying from Greenville, North Carolina to San Francisco in October is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Santa Clara
Manteca
Sunnyvale
Vacaville
Vallejo
Hollister
Foster City
Union City
Fairfield
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Redwood City
Lodi
San Mateo

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Top airline flying from Greenville to San Francisco

Discover the top airline that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$476FlexibilityNo cancel feeOn-time71%

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