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$447+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SFO
Jun 26 — Jul 31
Fri 6/26
Fri 7/3
1 adult, Economy
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Cheap flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 27, 2026.

This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:04 pm
PGV
-
SFO
1 stop7h 44m
American Airlines
Tue 7/211:20 pm
SFO
-
PGV
1 stop7h 32m
American Airlines
Deal found 5/27$447
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:03 pm
PGV
-
SFO
1 stop7h 46m
American Airlines
Tue 6/239:30 pm
SFO
-
PGV
1 stop10h 06m
American Airlines
Deal found 5/25$537
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:10 am
PGV
-
SFO
1 stop10h 07m
American Airlines
Sat 6/139:52 pm
SFO
-
PGV
1 stop9h 44m
American Airlines
Deal found 5/24$597
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:15 am
PGV
-
SFO
1 stop17h 51m
American Airlines
Sat 7/185:00 am
SFO
-
PGV
1 stop15h 52m
American Airlines
Deal found 5/27$882

Find flight deals from Greenville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 27, 2026.

Round-trip from

$447
(American Airlines)
From Pitt-Greenville to San Francisco
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 27, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Sat 7/11

6:04 pm-10:48 pm

1 stop7h 44m

San Francisco

Tue 7/21

1:20 pm-11:52 pm

1 stop7h 32m

$447

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Fri 6/19

6:03 pm-10:49 pm

1 stop7h 46m

San Francisco

Tue 6/23

9:30 pm-10:36 am

1 stop10h 06m

$537

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Tue 6/9

5:10 am-1:04 pm

2 stops10h 54m

San Francisco

Sat 6/13

9:52 pm-10:36 am

1 stop9h 44m

$602

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Sat 7/11

5:15 am-8:06 pm

1 stop17h 51m

San Francisco

Sat 7/18

5:00 am-11:52 pm

1 stop15h 52m

$882

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Mon 6/8

5:10 am-12:17 pm

1 stop10h 07m

San Francisco

Fri 6/12

5:00 am-5:38 pm

1 stop9h 38m

$1,157
Cheapest one-way
Quickest one-way

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Wed 6/3

11:03 am-7:10 pm

2 stops11h 07m

$577

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/27

Sorted by cheapest first

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville, North Carolina to San Francisco?

    A quick flight from Greenville, North Carolina to San Francisco can take about 7h 44m. American Airlines provides one of the quickest options available for as low as $447. There are 2473 mi between Greenville, North Carolina and San Francisco.

  • Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

  • Can I find deals for business class flights from Greenville to San Francisco?

    Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Cupertino
San Bruno
Watsonville
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
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Sunnyvale
Turlock
Vallejo
San Lorenzo
Davis
Emeryville

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