$540+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SFO
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:05 am -
1 stop7h 47m
Sat 9/196:12 am -
1 stop7h 40m
Deal found 8/17![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:10 am -
1 stop8h 18m
Sat 9/511:29 pm -
1 stop8h 07m
Deal found 8/17![American Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am -
1 stop8h 18m
Sun 9/611:40 pm -
1 stop9h 16m
Deal found 8/18![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:21 pm -
1 stop9h 57m
Sun 9/611:40 pm -
1 stop9h 16m
Deal found 8/20![American Airlines logo]()
$743
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:23 pm -
1 stop9h 55m
Mon 8/2411:40 pm -
1 stop9h 16m
Deal found 8/19![American Airlines logo]()
$811
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:05 am -
1 stop7h 47m
Sat 9/196:12 am -
1 stop7h 40m
Deal found 8/17![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:10 am -
1 stop8h 18m
Sat 9/511:29 pm -
1 stop8h 07m
Deal found 8/17![American Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am -
1 stop8h 18m
Sun 9/611:40 pm -
1 stop9h 16m
Deal found 8/18![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:21 pm -
1 stop9h 57m
Sun 9/611:40 pm -
1 stop9h 16m
Deal found 8/20![American Airlines logo]()
$743
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:21 pm -
2 stops13h 19m
Tue 9/88:45 am -
2 stops11h 14m
Deal found 8/20![American Airlines logo]()
$938
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated August 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:23 pm -
1 stop9h 55m
Mon 8/2411:40 pm -
1 stop9h 16m
Deal found 8/19![American Airlines logo]()
$811
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:10 am -
1 stop8h 18m
Sat 9/511:29 pm -
1 stop8h 07m
Deal found 8/17![American Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am -
1 stop8h 18m
Sun 9/611:40 pm -
1 stop9h 16m
Deal found 8/18![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:21 pm -
1 stop9h 57m
Sun 9/611:40 pm -
1 stop9h 16m
Deal found 8/20![American Airlines logo]()
$743
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:05 am -
1 stop7h 47m
Sat 9/196:12 am -
1 stop7h 40m
Deal found 8/17![American Airlines logo]()
$592
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/196:00 am -
1 stop10h 50m
Deal found 8/17![American Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:10 am -
1 stop8h 18m
Deal found 8/17![American Airlines logo]()
$584
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Round-trip from | $592 (American Airlines) |
|---|---|
One-way from | $540 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Tue 9/15
6:05 am-10:52 am
1 stop7h 47m
San Francisco
Sat 9/19
6:12 am-4:52 pm
1 stop7h 40m
$592
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Tue 9/1
6:10 am-11:28 am
1 stop8h 18m
San Francisco
Sat 9/5
11:29 pm-10:36 am
1 stop8h 07m
$639
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Wed 9/2
6:10 am-11:28 am
1 stop8h 18m
San Francisco
Sun 9/6
11:40 pm-11:56 am
1 stop9h 16m
$691
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Thu 9/3
12:21 pm-7:18 pm
1 stop9h 57m
San Francisco
Sun 9/6
11:40 pm-11:56 am
1 stop9h 16m
$743
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Fri 9/4
12:21 pm-10:40 pm
2 stops13h 19m
San Francisco
Tue 9/8
8:45 am-10:59 pm
2 stops11h 14m
$938
Cheapest one-way
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Tue 1/19
6:00 am-1:50 pm
1 stop10h 50m
$540
Quickest one-way
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Thu 9/3
6:10 am-11:28 am
1 stop8h 18m
$584
Sorted by cheapest first
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
PGV-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Emeryville
Roseville
Burlingame
Rancho Cordova
Fairfield
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
Manteca
San Carlos
Turlock
San Lorenzo
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