$547+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SFO
Nov 15 — Nov 221
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
Cheapest
Best
Last-minute
Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2026.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:15 pm -
1 stop8h 17m
Mon 11/235:00 am -
1 stop9h 30m
Deal found 10/15![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:58 pm -
1 stop8h 09m
Sun 11/15:00 am -
1 stop9h 36m
Deal found 10/12![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:05 am -
1 stop7h 46m
Mon 11/25:00 am -
1 stop8h 50m
Deal found 10/14![American Airlines logo]()
$629
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 16, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 16, 2026.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:15 pm -
1 stop8h 17m
Mon 11/235:00 am -
1 stop9h 30m
Deal found 10/15![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:58 pm -
1 stop8h 09m
Tue 11/35:00 am -
1 stop8h 50m
Deal found 10/15![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:05 am -
2 stops11h 05m
Sun 11/15:00 am -
1 stop9h 36m
Deal found 10/12![American Airlines logo]()
$674
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:05 am -
2 stops13h 05m
Mon 11/25:00 am -
1 stop8h 50m
Deal found 10/14![American Airlines logo]()
$724
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated October 16, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated October 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:58 pm -
1 stop8h 09m
Sun 11/15:00 am -
1 stop9h 36m
Deal found 10/12![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:05 am -
1 stop7h 46m
Mon 11/25:00 am -
1 stop8h 50m
Deal found 10/14![American Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:15 pm -
1 stop8h 17m
Mon 11/235:00 am -
1 stop9h 30m
Deal found 10/15![American Airlines logo]()
$547
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2026.
Round-trip from | $547 (American Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 16, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Mon 11/16
5:15 pm-10:32 pm
1 stop8h 17m
San Francisco
Mon 11/23
5:00 am-5:30 pm
1 stop9h 30m
$547
Quickest round-trip
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Fri 10/30
5:58 pm-11:07 pm
1 stop8h 09m
San Francisco
Tue 11/3
5:00 am-4:50 pm
1 stop8h 50m
$592
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Wed 10/28
5:05 am-1:10 pm
2 stops11h 05m
San Francisco
Sun 11/1
5:00 am-5:36 pm
1 stop9h 36m
$674
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Thu 10/29
5:05 am-3:10 pm
2 stops13h 05m
San Francisco
Mon 11/2
5:00 am-4:50 pm
1 stop8h 50m
$724
Sorted by cheapest first
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
PGV-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
San Bruno
Emeryville
Burlingame
Roseville
Redwood City
Rancho Cordova
Cupertino
Newark
Fairfield
San Ramon
Manteca
San Carlos
Vallejo
Turlock
Davis
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