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$474+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SFO
Apr 1 — Apr 81
Wed 4/1
Wed 4/8
1 adult, Economy
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Cheap flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 2, 2026.

This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:03 pm
PGV
-
SFO
1 stop8h 07m
American Airlines
Fri 3/2712:26 am
SFO
-
PGV
1 stop7h 14m
American Airlines
Deal found 2/26$474
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:03 pm
PGV
-
SFO
1 stop7h 46m
American Airlines
Mon 5/255:14 am
SFO
-
PGV
1 stop9h 24m
American Airlines
Deal found 2/27$514
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:03 pm
PGV
-
SFO
1 stop8h 07m
American Airlines
Tue 3/1712:31 pm
SFO
-
PGV
1 stop7h 28m
American Airlines
Deal found 2/26$557
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:56 pm
PGV
-
SFO
1 stop7h 54m
American Airlines
Sat 12/1211:50 pm
SFO
-
PGV
1 stop7h 43m
American Airlines
Deal found 2/27$575

Find flight deals from Greenville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 2, 2026.

Round-trip from

$474
(American Airlines)
From Pitt-Greenville to San Francisco
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Mon 3/23

6:03 pm-11:10 pm

1 stop8h 07m

San Francisco

Fri 3/27

12:26 am-10:40 am

1 stop7h 14m

$474

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Thu 5/21

6:03 pm-10:49 pm

1 stop7h 46m

San Francisco

Mon 5/25

5:14 am-5:38 pm

1 stop9h 24m

$514

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Fri 3/13

6:03 pm-11:10 pm

1 stop8h 07m

San Francisco

Tue 3/17

12:31 pm-10:59 pm

1 stop7h 28m

$557

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Sun 3/15

5:05 am-12:17 pm

1 stop10h 12m

San Francisco

Thu 3/19

7:00 am-5:35 pm

1 stop7h 35m

$1,097

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/26

Sorted by cheapest first

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

Currently, April is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $159). Flying from Greenville, North Carolina to San Francisco in February is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville, North Carolina to San Francisco?

    A quick flight from Greenville, North Carolina to San Francisco can take about 8h 07m. American Airlines provides one of the quickest options available for as low as $474. There are 2473 mi between Greenville, North Carolina and San Francisco.

  • Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

  • Can I find deals for business class flights from Greenville to San Francisco?

    Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

    Currently, April is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $159). Flying from Greenville, North Carolina to San Francisco in February is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Livermore
Roseville
Watsonville
San Bruno
Daly City
Sunnyvale
Vacaville
Turlock
San Carlos
San Ramon
Redwood City
Rancho Cordova
San Lorenzo
Davis
Hollister
Manteca
Union City

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