How long is the flight from Greenville, North Carolina to San Francisco?

A quick flight from Greenville, North Carolina to San Francisco can take about 10h 50m. American Airlines provides one of the quickest options available for as low as $557. There are 2473 mi between Greenville, North Carolina and San Francisco.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What is the cheapest time of day to fly from PGV to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Greenville, North Carolina to San Francisco as you normally would.

Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Greenville to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

Can I find deals for business class flights from Greenville to San Francisco?

Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$557+ Flights from Greenville, NC to San Francisco

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Cheap flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

Tue 2/106:00 am

PGV

SFO

1 stop10h 50m

American Airlines

Sat 2/141:17 pm

SFO

PGV

1 stop7h 33m

American Airlines

Deal found 1/26

$557

Best flights from Greenville to San Francisco
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 28, 2026.

Tue 2/106:00 am

PGV

SFO

1 stop10h 50m

American Airlines

Sat 2/141:17 pm

SFO

PGV

1 stop7h 33m

American Airlines

Deal found 1/26

$557

Wed 2/116:00 am

PGV

SFO

1 stop10h 50m

American Airlines

Sat 2/1412:25 am

SFO

PGV

1 stop7h 10m

American Airlines

Deal found 1/27

$557

Last-minute flights from Greenville to San Francisco
Discover last-minute flight deals from Greenville to San Francisco. Data last updated January 28, 2026 and is based on user searches.

Tue 2/106:00 am

PGV

SFO

1 stop10h 50m

American Airlines

Sat 2/141:17 pm

SFO

PGV

1 stop7h 33m

American Airlines

Deal found 1/26

$557

Find flight deals from Greenville to San Francisco

Round-trip from	$557 (American Airlines)

From Pitt-Greenville to San Francisco

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Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Tue 2/10

6:00 am-1:50 pm

1 stop10h 50m

San Francisco

Sat 2/14

1:17 pm-11:50 pm

1 stop7h 33m

$557

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Wed 2/11

6:00 am-1:50 pm

1 stop10h 50m

San Francisco

Sat 2/14

12:25 am-10:35 am

1 stop7h 10m

$557

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

Currently, April is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $147). Flying from Greenville, North Carolina to San Francisco in January is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

How long is the flight from Greenville, North Carolina to San Francisco?
A quick flight from Greenville, North Carolina to San Francisco can take about 10h 50m. American Airlines provides one of the quickest options available for as low as $557. There are 2473 mi between Greenville, North Carolina and San Francisco.
Can I find deals for flights from Greenville to San Francisco that include hotel bookings?
Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Greenville to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.
Can I find deals for business class flights from Greenville to San Francisco?
Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?
Currently, April is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $147). Flying from Greenville, North Carolina to San Francisco in January is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$557+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Greenville to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

Find flight deals from Greenville to San Francisco

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Greenville, North Carolina to San Francisco?

Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

How can I find direct flights from Greenville to San Francisco?

Can I find deals for business class flights from Greenville to San Francisco?

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

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Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.