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$417+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SFO
Aug 15 — Aug 221
Fri 8/15
Fri 8/22
1 adult, Economy
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Cheap flight deals from Greenville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2025.

Round-trip from

$417
(American Airlines)
From Pitt-Greenville to San Francisco
Search Deals

Find flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2025.

This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:00 amPGV - SFO
1 stop8h 30mAmerican Airlines
Sat 10/412:38 pmSFO - PGV
1 stop7h 48mAmerican Airlines
Deal found 8/10$417
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:51 pmPGV - SFO
1 stop10h 11mAmerican Airlines
Fri 10/1012:50 amSFO - PGV
2 stops10h 51mAmerican Airlines
Deal found 8/10$452
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/163:10 pmPGV - SFO
1 stop8h 19mAmerican Airlines
Sat 8/2310:40 pmSFO - PGV
1 stop8h 50mAmerican Airlines
Deal found 8/10$523
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/412:51 pmPGV - SFO
1 stop10h 11mAmerican Airlines
Sat 9/2012:38 pmSFO - PGV
1 stop7h 48mAmerican Airlines
Deal found 8/10$547
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/412:51 pmPGV - SFO
1 stop10h 11mAmerican Airlines
Thu 9/186:45 amSFO - PGV
2 stops14h 14mAmerican Airlines
Deal found 8/10$552
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:00 amPGV - SFO
2 stops10h 10mAmerican Airlines
Fri 9/198:00 amSFO - PGV
2 stops12h 26mAmerican Airlines
Deal found 8/10$557
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2512:11 pmPGV - SFO
1 stop10h 35mAmerican Airlines
Fri 8/2911:30 pmSFO - PGV
1 stop16h 54mAmerican Airlines
Deal found 8/10$1,019

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2025.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Greenville

Fly to

San Francisco

Route

Depart

Return

Price

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Fri 9/19

6:00 am-11:30 am

1 stop8h 30m

San Francisco

Sat 10/4

12:38 pm-11:26 pm

1 stop7h 48m

$417

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Fri 9/26

12:51 pm-8:02 pm

1 stop10h 11m

San Francisco

Fri 10/10

12:50 am-2:41 pm

2 stops10h 51m

$452

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Sat 8/23

3:10 pm-8:29 pm

1 stop8h 19m

San Francisco

Wed 8/27

8:10 am-6:40 pm

1 stop7h 30m

$517

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Sat 8/16

3:10 pm-8:29 pm

1 stop8h 19m

San Francisco

Sat 8/23

10:40 pm-10:30 am

1 stop8h 50m

$523

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Thu 9/4

12:51 pm-8:02 pm

1 stop10h 11m

San Francisco

Sat 9/20

12:38 pm-11:26 pm

1 stop7h 48m

$547

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/10

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $276). Flying from Greenville, North Carolina to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 10, 2025.
Peruse reviews from past customers who have flown with American Airlines from Greenville to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Boarding

7.5

Entertainment

6.9

Food

6.5

Reviews

1 / 20
8.0
Excellent

Aaron,Sep 2023

CLT - ORD

The extra cost of first class was not worth it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Boarding

7.5

Entertainment

6.9

Food

6.5

Reviews

1 / 20
8.0
Excellent

Aaron,Sep 2023

CLT - ORD

The extra cost of first class was not worth it.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Greenville, North Carolina to San Francisco round-trip?

    Currently priced at $417, American Airlines will fly you from Greenville, North Carolina to San Francisco and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

  • Can I find deals for business class flights from Greenville to San Francisco?

    Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $276). Flying from Greenville, North Carolina to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Livermore
South San Francisco
Turlock
Hollister
Antioch
Watsonville
Manteca
Sunnyvale
Newark
Milpitas
Santa Clara
Campbell
Foster City
San Leandro
Burlingame
Redwood City
Vallejo

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Top airline flying from Greenville to San Francisco

Discover the top airline that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$416FlexibilityNo cancel feeOn-time71%

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