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$540+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SFO
Sep 5 — Sep 121
Sat 9/5
Sat 9/12
1 adult, Economy
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Cheap flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.

This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:55 am -
1 stop7h 53m
Wed 9/912:00 pm -
1 stop7h 59m
Deal found 8/3$545
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:11 pm -
1 stop8h 57m
Mon 9/2811:03 pm -
1 stop9h 37m
Deal found 8/3$619
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:00 am -
1 stop10h 14m
Sat 8/225:05 am -
1 stop8h 44m
Deal found 8/2$691
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:10 am -
2 stops12h 52m
Tue 8/256:36 am -
2 stops13h 23m
Deal found 8/5$937
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:05 am -
1 stop7h 53m
Thu 9/2411:03 pm -
1 stop9h 37m
Deal found 8/3$945

Find flight deals from Greenville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 6, 2026.

Round-trip from

$545
(American Airlines)

One-way from

$540
(American Airlines)
From Pitt-Greenville to San Francisco
Search Deals
One-way flight from Pitt-Greenville to San Francisco
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Francisco

PGV Pitt-Greenville - SFO San Francisco

PGVSFO

Pitt-Greenville

Sat 9/5

8:55 am-7:05 pm

2 stops13h 10m

San Francisco

Wed 9/9

5:50 am-10:59 pm

2 stops14h 09m

$589

GreenvilleSan Francisco

PGV Pitt-Greenville - SFO San Francisco

PGVSFO

Pitt-Greenville

Thu 9/24

12:11 pm-6:08 pm

1 stop8h 57m

San Francisco

Mon 9/28

11:03 pm-11:40 am

1 stop9h 37m

$619

GreenvilleSan Francisco

PGV Pitt-Greenville - SFO San Francisco

PGVSFO

Pitt-Greenville

Sun 8/16

5:00 am-12:14 pm

1 stop10h 14m

San Francisco

Sat 8/22

5:05 am-4:49 pm

1 stop8h 44m

$691
Quickest round-trip

GreenvilleSan Francisco

PGV Pitt-Greenville - SFO San Francisco

PGVSFO

Pitt-Greenville

Fri 8/21

12:21 pm-7:18 pm

1 stop9h 57m

San Francisco

Tue 8/25

6:30 am-4:49 pm

1 stop7h 19m

$691
Cheapest one-way
Quickest one-way

GreenvilleSan Francisco

PGV Pitt-Greenville - SFO San Francisco

PGVSFO

Pitt-Greenville

Tue 9/15

6:05 am-10:52 am

1 stop7h 47m

$540

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/3

Sorted by cheapest first

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville, North Carolina to San Francisco?

    A quick flight from Greenville, North Carolina to San Francisco can take about 13h 10m. American Airlines provides one of the quickest options available for as low as $589. There are 2473 mi between Greenville, North Carolina and San Francisco.

  • Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

  • Can I find deals for business class flights from Greenville to San Francisco?

    Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
San Bruno
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
Vallejo
Cupertino
Newark
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Turlock
San Lorenzo
Davis

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