$379+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SFO
Oct 16 — Oct 231
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:05 am -
1 stop7h 47m
Sat 10/36:12 am -
1 stop7h 40m
Deal found 9/14![American Airlines logo]()
$659
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:09 am -
1 stop10h 00m
Thu 10/16:12 am -
1 stop7h 40m
Deal found 9/11![American Airlines logo]()
$1,187
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
1 stop9h 42m
Tue 1/265:00 am -
1 stop8h 49m
Deal found 9/13![American Airlines logo]()
$602
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:05 am -
1 stop7h 47m
Sat 10/36:12 am -
1 stop7h 40m
Deal found 9/14![American Airlines logo]()
$659
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:09 am -
1 stop10h 00m
Thu 10/16:12 am -
1 stop7h 40m
Deal found 9/11![American Airlines logo]()
$1,187
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:11 pm -
1 stop8h 57m
Fri 10/26:12 am -
1 stop7h 40m
Deal found 9/13![American Airlines logo]()
$1,187
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated September 16, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated September 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:09 am -
1 stop10h 00m
Thu 10/16:12 am -
1 stop7h 40m
Deal found 9/11![American Airlines logo]()
$1,187
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:05 am -
1 stop7h 47m
Sat 10/36:12 am -
1 stop7h 40m
Deal found 9/14![American Airlines logo]()
$659
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:11 am -
1 stop9h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$379
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2026.
Round-trip from | $602 (American Airlines) |
|---|---|
One-way from | $379 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Mon 11/2
6:11 am-12:23 pm
1 stop9h 12m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$379
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Thu 1/21
6:00 am-12:42 pm
1 stop9h 42m
San Francisco
Tue 1/26
5:00 am-4:49 pm
1 stop8h 49m
$602
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Tue 9/29
6:05 am-10:52 am
1 stop7h 47m
San Francisco
Sat 10/3
6:12 am-4:52 pm
1 stop7h 40m
$659
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Sun 9/27
5:09 am-12:09 pm
1 stop10h 00m
San Francisco
Thu 10/1
6:12 am-4:52 pm
1 stop7h 40m
$1,187
GreenvilleSan Francisco
PGV Pitt-Greenville - SFO San Francisco
PGVSFO
Pitt-Greenville
Mon 9/28
12:11 pm-6:08 pm
1 stop8h 57m
San Francisco
Fri 10/2
6:12 am-4:52 pm
1 stop7h 40m
$1,187
Sorted by cheapest first
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
PGV-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Emeryville
San Bruno
Burlingame
Rancho Cordova
Roseville
Fairfield
Hayward
Cupertino
Newark
San Ramon
Redwood City
Manteca
Vallejo
San Carlos
Turlock
Davis
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