$151+ Cheap flights from Durham, NC to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SFO
Jun 18 — Jun 251
Round-trip
1 adult, Economy
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Find cheap flights from Durham to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Durham to San Francisco are usually found in July or January, booked 84 days in advance, depart on a Thursday or Friday and return on a Wednesday
Cheap flight deals from Durham to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Durham to San FranciscoExplore the most affordable flight options available from Durham to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 19, 2026.
Explore the most affordable flight options available from Durham to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 19, 2026.
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:15 pm
RDU
- SFO
1 stop9h 54m
American Airlines
Sun 6/148:24 pm
SFO
- RDU
1 stop7h 10m
American Airlines
Deal found 5/16![American Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:15 am
RDU
- SFO
2 stops17h 35m
Frontier
Tue 9/112:33 pm
SFO
- RDU
1 stop19h 58m
Frontier
Deal found 5/14![Frontier logo]()
$344
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:35 am
RDU
- SFO
Nonstop5h 42m
United Airlines
Sat 6/65:05 am
SFO
- RDU
1 stop9h 22m
United Airlines
Deal found 5/14![United Airlines logo]()
$346
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:00 am
RDU
- SFO
1 stop10h 28m
United Airlines
Thu 6/2512:50 am
SFO
- RDU
1 stop10h 11m
United Airlines
Deal found 5/14![United Airlines logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:40 am
RDU
- SFO
1 stop14h 54m
Multiple Airlines
Mon 8/2411:52 pm
SFO
- RDU
1 stop9h 43m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:34 am
RDU
- SFO
Nonstop5h 46m
United Airlines
Mon 8/2411:59 pm
SFO
- RDU
Nonstop5h 20m
United Airlines
Deal found 5/15![United Airlines logo]()
$349
This Frontier deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:59 pm
RDU
- SFO
1 stop9h 14m
Frontier
Mon 8/109:39 pm
SFO
- RDU
1 stop10h 52m
Frontier
Deal found 5/18![Frontier logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:33 pm
RDU
- SFO
1 stop10h 24m
Frontier
Tue 7/76:00 am
SFO
- RDU
1 stop26h 31m
Frontier
Deal found 5/16![Frontier logo]()
$351
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:59 pm
RDU
- SFO
1 stop8h 58m
United Airlines
Mon 11/1611:59 pm
SFO
- RDU
2 stops11h 05m
United Airlines
Deal found 5/14![United Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:28 pm
RDU
- SFO
1 stop7h 51m
American Airlines
Wed 6/1011:49 pm
SFO
- RDU
1 stop7h 33m
American Airlines
Deal found 5/19![American Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:10 pm
RDU
- SFO
2 stops9h 15m
Southwest
Wed 7/2912:15 pm
SFO
- RDU
1 stop8h 10m
Southwest
Deal found 5/17![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:34 am
RDU
- SFO
Nonstop5h 46m
United Airlines
Sat 9/196:00 am
SFO
- RDU
1 stop8h 41m
United Airlines
Deal found 5/16![United Airlines logo]()
$355
Best flights from Durham to San FranciscoDiscover carefully curated flight deals from Durham to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 19, 2026.
Discover carefully curated flight deals from Durham to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 19, 2026.
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:27 pm
RDU
- SFO
Nonstop5h 43m
United Airlines
Tue 8/412:45 am
SFO
- RDU
1 stop8h 17m
United Airlines
Deal found 5/16![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/295:40 pm
RDU
- SFO
2 stops9h 50m
Southwest
Sun 7/59:50 am
SFO
- RDU
1 stop12h 00m
Southwest
Deal found 5/17![Southwest logo]()
$380
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/212:45 pm
RDU
- SFO
2 stops8h 55m
Southwest
Sun 7/59:50 am
SFO
- RDU
1 stop12h 00m
Southwest
Deal found 5/14![Southwest logo]()
$380
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
RDU
- SFO
1 stop8h 19m
United Airlines
Wed 8/512:00 pm
SFO
- RDU
Nonstop5h 18m
United Airlines
Deal found 5/15![United Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:27 pm
RDU
- SFO
Nonstop5h 43m
United Airlines
Wed 7/2912:00 pm
SFO
- RDU
Nonstop5h 18m
United Airlines
Deal found 5/17![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:55 pm
RDU
- SFO
2 stops9h 35m
Southwest
Tue 7/2111:40 pm
SFO
- RDU
2 stops10h 10m
Southwest
Deal found 5/17![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:22 pm
RDU
- SFO
1 stop9h 34m
United Airlines
Sun 7/129:10 pm
SFO
- RDU
Nonstop5h 15m
United Airlines
Deal found 5/17![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:10 pm
RDU
- SFO
2 stops9h 15m
Southwest
Thu 7/165:10 am
SFO
- RDU
2 stops11h 30m
Southwest
Deal found 5/17![Southwest logo]()
$427
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2611:20 am
RDU
- SFO
2 stops10h 20m
Southwest
Sun 7/59:50 am
SFO
- RDU
1 stop12h 00m
Southwest
Deal found 5/18![Southwest logo]()
$434
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:25 am
RDU
- SFO
2 stops13h 32m
United Airlines
Tue 8/1812:35 am
SFO
- RDU
1 stop10h 32m
United Airlines
Deal found 5/15![United Airlines logo]()
$458
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:25 am
RDU
- SFO
1 stop6h 55m
Southwest
Wed 6/245:00 am
SFO
- RDU
1 stop9h 40m
Southwest
Deal found 5/14![Southwest logo]()
$447
Last-minute flights from Durham to San FranciscoDiscover last-minute flight deals from Durham to San Francisco. Data last updated May 19, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to San Francisco. Data last updated May 19, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:50 pm
RDU
- SFO
1 stop9h 30m
Southwest
Sun 5/3111:25 pm
SFO
- RDU
1 stop8h 10m
Southwest
Deal found 5/14![Southwest logo]()
$358
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:20 pm
RDU
- SFO
1 stop7h 50m
American Airlines
Fri 6/58:24 pm
SFO
- RDU
1 stop7h 10m
American Airlines
Deal found 5/15![American Airlines logo]()
$357
This Expedia deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:54 pm
RDU
- SFO
1 stop10h 03m
Frontier
Wed 6/310:10 pm
SFO
- RDU
1 stop10h 49m
Frontier
Deal found 5/17![Frontier logo]()
$350
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:28 pm
RDU
- SFO
1 stop7h 51m
American Airlines
Wed 6/1011:49 pm
SFO
- RDU
1 stop7h 33m
American Airlines
Deal found 5/19![American Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:00 am
RDU
- SFO
2 stops13h 10m
United Airlines
Mon 6/812:50 am
SFO
- RDU
1 stop8h 43m
United Airlines
Deal found 5/15![United Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:35 am
RDU
- SFO
Nonstop5h 42m
United Airlines
Sat 6/65:05 am
SFO
- RDU
1 stop9h 22m
United Airlines
Deal found 5/14![United Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:33 pm
RDU
- SFO
1 stop10h 24m
Frontier
Tue 7/76:00 am
SFO
- RDU
1 stop26h 31m
Frontier
Deal found 5/16![Frontier logo]()
$351
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:26 pm
RDU
- SFO
1 stop8h 22m
American Airlines
Tue 6/2311:29 pm
SFO
- RDU
1 stop8h 19m
American Airlines
Deal found 5/17![American Airlines logo]()
$359
This CheapOair deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:33 pm
RDU
- SFO
1 stop10h 24m
Frontier
Wed 6/106:00 am
SFO
- RDU
1 stop26h 31m
Frontier
Deal found 5/18![Frontier logo]()
$360
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:15 pm
RDU
- SFO
1 stop9h 54m
American Airlines
Sun 6/148:24 pm
SFO
- RDU
1 stop7h 10m
American Airlines
Deal found 5/16![American Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:00 am
RDU
- SFO
1 stop10h 28m
United Airlines
Thu 6/2512:50 am
SFO
- RDU
1 stop10h 11m
United Airlines
Deal found 5/14![United Airlines logo]()
$347
One-way flights from Durham to San FranciscoSearch for one-way flight options from Durham to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 19, 2026.
Search for one-way flight options from Durham to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:14 pm
RDU
- SFO
2 stops25h 13m
Frontier
Deal found 5/18![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1012:26 pm
RDU
- SFO
1 stop14h 52m
Frontier
Deal found 5/17![Frontier logo]()
$154
This iWofly deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure iWofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:54 pm
RDU
- SFO
1 stop10h 01m
Frontier
Deal found 5/18![Frontier logo]()
$155
This Super.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2312:26 pm
RDU
- SFO
1 stop15h 01m
Frontier
Deal found 5/18![Frontier logo]()
$157
This Super.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:26 pm
RDU
- SFO
1 stop14h 52m
Frontier
Deal found 5/16![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:26 pm
RDU
- SFO
1 stop15h 01m
Frontier
Deal found 5/14![Frontier logo]()
$161
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:00 am
RDU
- SFO
1 stop8h 14m
United Airlines
Deal found 5/14![United Airlines logo]()
$164
This KAYAK deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:40 am
RDU
- SFO
1 stop7h 44m
Delta
Deal found 5/14![Delta logo]()
$165
This CheapOair deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:26 pm
RDU
- SFO
1 stop14h 52m
Frontier
Deal found 5/18![Frontier logo]()
$166
This Super.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1612:59 pm
RDU
- SFO
1 stop9h 14m
Frontier
Deal found 5/15![Frontier logo]()
$168
Find flight deals from Durham to San Francisco
Keep the following information in mind while searching for Durham to San Francisco flight deals. Data was last updated May 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $343 (American Airlines) |
One-way from | $151 (Kiwi.com) |
Popular in | March |
Cheapest in | July |
Average price | $430 |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 19, 2026.
Use the filters below to find and compare flights from Durham to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Wed 7/29
5:27 pm-8:10 pm
Nonstop5h 43m
San Francisco
Tue 8/4
12:45 am-12:02 pm
1 stop8h 17m
$359
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Mon 6/29
5:40 pm-12:30 am
2 stops9h 50m
San Francisco
Sun 7/5
9:50 am-12:50 am
1 stop12h 00m
$380
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Thu 7/2
12:45 pm-6:40 pm
2 stops8h 55m
San Francisco
Sun 7/5
9:50 am-12:50 am
1 stop12h 00m
$380
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Tue 7/28
6:00 am-11:19 am
1 stop8h 19m
San Francisco
Wed 8/5
12:00 pm-8:18 pm
Nonstop5h 18m
$383
Quickest round-trip
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Wed 7/15
5:27 pm-8:10 pm
Nonstop5h 43m
San Francisco
Wed 7/29
12:00 pm-8:18 pm
Nonstop5h 18m
$389
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Sat 7/11
4:55 pm-11:30 pm
2 stops9h 35m
San Francisco
Tue 7/21
11:40 pm-12:50 pm
2 stops10h 10m
$393
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Fri 7/3
4:22 pm-10:56 pm
1 stop9h 34m
San Francisco
Sun 7/12
9:10 pm-5:25 am
Nonstop5h 15m
$399
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Tue 7/7
4:10 pm-10:25 pm
2 stops9h 15m
San Francisco
Thu 7/16
5:10 am-7:40 pm
2 stops11h 30m
$427
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Fri 6/26
11:20 am-6:40 pm
2 stops10h 20m
San Francisco
Sun 7/5
9:50 am-12:50 am
1 stop12h 00m
$434
RaleighSan Francisco
RDU - SFO
RDUSFO
Raleigh-Durham
Thu 6/18
6:25 am-10:20 am
1 stop6h 55m
San Francisco
Wed 6/24
5:00 am-5:40 pm
1 stop9h 40m
$447
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Durham to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Durham with our price prediction graph.
RDU-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to San Francisco
DU8-SFO
RDU-SFO
What is the cheapest time of day to fly from DU8 to SFO?
Find hourly flight availability from Durham to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 19, 2026.
When flying from Durham to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Durham to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 19, 2026.
Read through reviews of airlines operating flights from Durham to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Durham to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
Vallejo
San Lorenzo
Davis
Emeryville
Manteca
Elk Grove
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Alternative routes for Durham to San Francisco
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Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Durham to San Francisco by cabin class
Find flights from Durham to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and San Francisco flights
Browse other Durham and San Francisco flight options. Last updated on May 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 19, 2026.
Durham to San Francisco flights
Consider these flights traveling from Durham to San Francisco.
Top 7 airlines flying from Durham to San Francisco
Discover the top 7 airlines that operate flights from Durham to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$119 | Average$264 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$226 | Average$456 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$229 | Average$390 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$256 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$281 | Average$413 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$282 | Average$351 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$302 | Average$378 | FlexibilityNo cancel fee | On-time75% |