$246+ Cheap flights from the Cayman Islands to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SFO
Mar 6 — Mar 131
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Cayman Islands to San FranciscoExplore the most affordable flight options available from Cayman Islands to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
Explore the most affordable flight options available from Cayman Islands to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:55 pm
GCM
- SFO
1 stop12h 04m
JetBlue
Wed 2/1810:39 pm
SFO
- GCM
1 stop12h 26m
JetBlue
Deal found 2/2![JetBlue logo]()
$509
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:55 pm
GCM
- SFO
1 stop12h 04m
JetBlue
Thu 2/1911:30 pm
SFO
- GCM
1 stop12h 04m
JetBlue
Deal found 2/2![JetBlue logo]()
$605
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Tue 2/1710:55 pm
SFO
- GCM
2 stops14h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$681
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Wed 2/186:55 am
SFO
- GCM
2 stops25h 40m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:50 pm
GCM
- SFO
1 stop29h 41m
United Airlines
Wed 3/2512:43 am
SFO
- GCM
1 stop12h 47m
United Airlines
Deal found 2/1![United Airlines logo]()
$722
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:45 am
GCM
- SFO
2 stops16h 16m
American Airlines
Wed 3/2512:25 am
SFO
- GCM
1 stop8h 45m
American Airlines
Deal found 2/1![American Airlines logo]()
$736
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:12 pm
GCM
- SFO
1 stop12h 07m
Delta
Fri 3/2710:35 pm
SFO
- GCM
1 stop9h 10m
Delta
Deal found 2/3![Delta logo]()
$747
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Thu 2/198:48 am
SFO
- GCM
2 stops23h 47m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$751
This Air Canada deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:25 pm
GCM
- SFO
1 stop24h 25m
Air Canada
Wed 6/171:40 pm
SFO
- GCM
1 stop19h 50m
Air Canada
Deal found 2/4![Air Canada logo]()
$765
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:40 pm
GCM
- SFO
2 stops13h 25m
Southwest
Thu 3/267:05 pm
SFO
- GCM
2 stops14h 40m
Southwest
Deal found 2/1![Southwest logo]()
$772
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:45 am
GCM
- SFO
2 stops15h 11m
American Airlines
Thu 3/2612:25 am
SFO
- GCM
1 stop8h 45m
American Airlines
Deal found 2/3![American Airlines logo]()
$776
Best flights from Cayman Islands to San FranciscoDiscover carefully curated flight deals from Cayman Islands to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
Discover carefully curated flight deals from Cayman Islands to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:55 pm
GCM
- SFO
1 stop12h 04m
JetBlue
Wed 2/1810:39 pm
SFO
- GCM
1 stop12h 26m
JetBlue
Deal found 2/2![JetBlue logo]()
$509
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Tue 2/1710:55 pm
SFO
- GCM
2 stops14h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$681
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:50 pm
GCM
- SFO
1 stop29h 41m
United Airlines
Wed 3/2512:43 am
SFO
- GCM
1 stop12h 47m
United Airlines
Deal found 2/1![United Airlines logo]()
$722
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:45 am
GCM
- SFO
2 stops16h 16m
American Airlines
Wed 3/2512:25 am
SFO
- GCM
1 stop8h 45m
American Airlines
Deal found 2/1![American Airlines logo]()
$736
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:12 pm
GCM
- SFO
1 stop12h 07m
Delta
Fri 3/2710:35 pm
SFO
- GCM
1 stop9h 10m
Delta
Deal found 2/3![Delta logo]()
$747
This Air Canada deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:25 pm
GCM
- SFO
1 stop24h 25m
Air Canada
Wed 6/171:40 pm
SFO
- GCM
1 stop19h 50m
Air Canada
Deal found 2/3![Air Canada logo]()
$765
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/141:25 pm
GCM
- SFO
2 stops12h 05m
Southwest
Wed 2/185:35 pm
SFO
- GCM
2 stops16h 20m
Southwest
Deal found 2/2![Southwest logo]()
$769
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:55 pm
GCM
- SFO
1 stop12h 04m
JetBlue
Thu 2/1911:30 pm
SFO
- GCM
1 stop12h 04m
JetBlue
Deal found 2/2![JetBlue logo]()
$605
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Wed 2/186:55 am
SFO
- GCM
2 stops25h 40m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Thu 2/198:48 am
SFO
- GCM
2 stops23h 47m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$751
Last-minute flights from Cayman Islands to San FranciscoDiscover last-minute flight deals from Cayman Islands to San Francisco. Data last updated February 4, 2026 and is based on user searches.
Discover last-minute flight deals from Cayman Islands to San Francisco. Data last updated February 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1311:25 am
GCM
- SFO
2 stops37h 30m
Multiple Airlines
Wed 2/181:45 pm
SFO
- GCM
1 stop20h 59m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$832
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:55 pm
GCM
- SFO
1 stop12h 04m
JetBlue
Wed 2/1810:39 pm
SFO
- GCM
1 stop12h 26m
JetBlue
Deal found 2/2![JetBlue logo]()
$509
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:55 pm
GCM
- SFO
1 stop12h 04m
JetBlue
Thu 2/1911:30 pm
SFO
- GCM
1 stop12h 04m
JetBlue
Deal found 2/2![JetBlue logo]()
$605
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Tue 2/1710:55 pm
SFO
- GCM
2 stops14h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$681
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Wed 2/186:55 am
SFO
- GCM
2 stops25h 40m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:40 pm
GCM
- SFO
1 stop20h 00m
Multiple Airlines
Thu 2/198:48 am
SFO
- GCM
2 stops23h 47m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$751
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/141:25 pm
GCM
- SFO
2 stops12h 05m
Southwest
Wed 2/185:35 pm
SFO
- GCM
2 stops16h 20m
Southwest
Deal found 2/2![Southwest logo]()
$769
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:50 pm
GCM
- SFO
1 stop29h 41m
United Airlines
Wed 3/2512:43 am
SFO
- GCM
1 stop12h 47m
United Airlines
Deal found 2/1![United Airlines logo]()
$722
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:45 am
GCM
- SFO
2 stops16h 16m
American Airlines
Wed 3/2512:25 am
SFO
- GCM
1 stop8h 45m
American Airlines
Deal found 2/1![American Airlines logo]()
$736
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:40 pm
GCM
- SFO
2 stops13h 25m
Southwest
Thu 3/267:05 pm
SFO
- GCM
2 stops14h 40m
Southwest
Deal found 2/1![Southwest logo]()
$772
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:12 pm
GCM
- SFO
1 stop12h 07m
Delta
Fri 3/2710:35 pm
SFO
- GCM
1 stop9h 10m
Delta
Deal found 2/3![Delta logo]()
$747
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:45 am
GCM
- SFO
2 stops15h 11m
American Airlines
Thu 3/2612:25 am
SFO
- GCM
1 stop8h 45m
American Airlines
Deal found 2/3![American Airlines logo]()
$776
One-way flights from Cayman Islands to San FranciscoSearch for one-way flight options from Cayman Islands to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
Search for one-way flight options from Cayman Islands to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
This JetBlue deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:15 pm
GCM
- SFO
1 stop11h 44m
JetBlue
Deal found 2/3![JetBlue logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:49 pm
GCM
- SFO
2 stops33h 50m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/12:49 pm
GCM
- SFO
3 stops31h 34m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$299
This Priceline deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/273:40 pm
GCM
- SFO
1 stop30h 54m
JetBlue
Deal found 2/3![JetBlue logo]()
$310
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:50 pm
GCM
- SFO
2 stops23h 15m
Southwest
Deal found 2/3![Southwest logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:30 am
GCM
- SFO
2 stops37h 09m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:50 am
GCM
- SFO
2 stops39h 49m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:45 pm
GCM
- SFO
3 stops28h 13m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$370
Find flight deals from Cayman Islands to San Francisco
Keep the following information in mind while searching for Cayman Islands to San Francisco flight deals. Data was last updated February 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $509 (JetBlue) |
One-way from | $246 (JetBlue) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cayman Islands to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from the Cayman Islands to San Francisco that are best for you.
Fly from
Cayman Islands
Fly to
San Francisco
Route
Depart
Return
Price
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 2/14
2:55 pm-11:59 pm
1 stop12h 04m
San Francisco
Wed 2/18
10:39 pm-2:05 pm
1 stop12h 26m
$509
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 2/14
2:55 pm-11:59 pm
1 stop12h 04m
San Francisco
Thu 2/19
11:30 pm-2:34 pm
1 stop12h 04m
$605
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 2/14
7:40 pm-12:40 pm
1 stop20h 00m
San Francisco
Tue 2/17
10:55 pm-4:05 pm
2 stops14h 10m
$681
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 2/14
7:40 pm-12:40 pm
1 stop20h 00m
San Francisco
Wed 2/18
6:55 am-11:35 am
2 stops25h 40m
$690
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Thu 3/19
1:50 pm-5:31 pm
1 stop29h 41m
San Francisco
Wed 3/25
12:43 am-3:30 pm
1 stop12h 47m
$722
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Thu 3/19
7:45 am-10:01 pm
2 stops16h 16m
San Francisco
Wed 3/25
12:25 am-11:10 am
1 stop8h 45m
$736
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Fri 3/20
1:12 pm-11:19 pm
1 stop12h 07m
San Francisco
Fri 3/27
10:35 pm-9:45 am
1 stop9h 10m
$747
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 2/14
7:40 pm-12:40 pm
1 stop20h 00m
San Francisco
Thu 2/19
8:48 am-11:35 am
2 stops23h 47m
$751
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 6/13
12:25 pm-10:50 am
1 stop24h 25m
San Francisco
Wed 6/17
1:40 pm-11:30 am
1 stop19h 50m
$765
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 2/14
1:25 pm-10:30 pm
2 stops12h 05m
San Francisco
Wed 2/18
5:35 pm-12:55 pm
2 stops16h 20m
$769
Showing 1-10 of 20 results
Best time to book a flight from Cayman Islands to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Cayman Islands with our price prediction graph.
GCM-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the Cayman Islands to San Francisco
KY0-SFO
GCM-SFO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated February 4, 2026.
Get a feel of what it's like to fly with American Airlines from the Cayman Islands to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.0
Food
6.4
Comfort
7.2
Boarding
7.5
Overall
7.2
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Crew
8.0
Food
6.4
Comfort
7.2
Boarding
7.5
Overall
7.2
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Related info for your journey
Find useful and relevant information for your journey from Cayman Islands to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
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Santa Cruz
Santa Clara
Roseville
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Watsonville
San Bruno
Daly City
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Turlock
Vacaville
San Carlos
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Davis
Hollister
Redwood City
Manteca
Union City
Elk Grove
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Top airline flying from Cayman Islands to San Francisco
Discover the top airline that operate flights from Cayman Islands to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$709 | Average$734 | FlexibilityNo cancel fee | On-time71% |