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$417+ Cheap flights from the Cayman Islands to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SFO
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Cayman Islands to San Francisco

Keep the following information in mind while searching for Cayman Islands to San Francisco flight deals. Data was last updated July 30, 2025.

Round-trip from

$575
(American Airlines)

One-way from

$417
(American Airlines)

Popular in

October

Cheapest in

February

Average price

$903
From Cayman Islands to San Francisco
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One-way flight from Cayman Islands to San Francisco
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Highest demand for flights based on searches. 15% potential increase in price ($121 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Cayman Islands to San Francisco

Cheapest flights from Cayman Islands to San Francisco
Explore the most affordable flight options available from Cayman Islands to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:25 amGCM - SFO
1 stop16h 34mAmerican Airlines
Tue 10/2811:36 pmSFO - GCM
1 stop9h 44mAmerican Airlines
Deal found 7/29$575
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/131:35 pmGCM - SFO
1 stop24h 03mUnited Airlines
Fri 9/1912:43 amSFO - GCM
1 stop9h 47mUnited Airlines
Deal found 7/30$791
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1211:25 amGCM - SFO
2 stops26h 58mMultiple Airlines
Fri 9/1912:50 pmSFO - GCM
3 stops21h 52mMultiple Airlines
Deal found 7/29$902

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cayman Islands to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from the Cayman Islands to San Francisco that are best for you.

Fly from

Cayman Islands

Fly to

San Francisco

Route

Depart

Return

Price

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Fri 10/24

8:25 am-10:59 pm

1 stop16h 34m

San Francisco

Tue 10/28

11:36 pm-11:20 am

1 stop9h 44m

$575

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 9/13

1:35 pm-11:38 am

1 stop24h 03m

San Francisco

Fri 9/19

12:43 am-12:30 pm

1 stop9h 47m

$791

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Fri 9/12

11:25 am-12:23 pm

2 stops26h 58m

San Francisco

Fri 9/19

12:50 pm-12:42 pm

3 stops21h 52m

$902

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Tue 1/13

4:15 pm-11:08 pm

1 stop9h 53m

$417

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Tue 1/13

2:40 pm-12:54 am

1 stop13h 14m

$433

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Mon 1/5

3:45 pm-10:44 am

2 stops21h 59m

$518

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Mon 1/5

5:45 pm-12:21 am

1 stop9h 36m

$533

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sun 1/4

1:30 pm-11:05 am

2 stops24h 35m

$675

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 1/3

4:00 pm-7:38 am

1 stop18h 38m

$859

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Cayman Islands to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Cayman Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Cayman Islands to San Francisco

What is the cheapest month to book a flight from Cayman Islands to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Cayman Islands to San Francisco (average of $276). Flying from Cayman Islands to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from the Cayman Islands to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Delta
8.0
Very good
7,980 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
JetBlue
7.3
Good
2,913 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

Find useful and relevant information for your journey from Cayman Islands to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Cayman Islands?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Cayman Islands to San Francisco.

  • What are the cheapest airlines to fly from Cayman Islands to San Francisco one-way?

    One-way options have recently been found by users for as low as $417 on American Airlines. Other airlines that offer cheap prices include JetBlue from $433 and Delta from $518 one-way.

  • Can I find deals for flights from Cayman Islands to San Francisco that include hotel bookings?

    Yes. In addition to deals on Cayman Islands to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cayman Islands to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cayman Islands to San Francisco.

  • Can I find deals for business class flights from Cayman Islands to San Francisco?

    Yes. Cheapflights offers flight deals from Cayman Islands to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cayman Islands to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Cayman Islands to San Francisco (average of $276). Flying from Cayman Islands to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
South San Francisco
Livermore
Turlock
Manteca
Antioch
Hollister
Watsonville
Sunnyvale
Newark
Milpitas
Campbell
Foster City
Capitola
Santa Clara
San Leandro
Burlingame
Redwood City

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Top airline flying from Cayman Islands to San Francisco

Discover the top airline that operate flights from Cayman Islands to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$653Average$734FlexibilityNo cancel feeOn-time71%

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