What are the cheapest airlines flying from Santo Domingo to Santa Ana round-trip?

According to our current data, Spirit Airlines ($427), United Airlines ($556), and American Airlines ($643) offers the cheapest pricing from Santo Domingo to Santa Ana.

What is the cheapest day to fly from Santo Domingo to Santa Ana?

Travelers seeking maximum savings on their Santo Domingo to Santa Ana flight should consider departing on Tuesday mornings when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santa Ana ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santa Ana, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What is the cheapest day to fly round-trip from Santo Domingo to Santa Ana?

Monday flights are generally found to be more expensive for flights from Santo Domingo to Santa Ana. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Santa Ana.

How far in advance should I book a flight from Santo Domingo to Santa Ana?

To save up to 64% on this flight, we recommend booking at least 37 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Santo Domingo to Santa Ana from $558 1-2 weeks out and tickets from $790 for flights departing within the next 72 hours.

What is the cheapest month to fly from Santo Domingo to Santa Ana?

Our data shows that January tends to be the cheapest month to fly to Santa Ana from Santo Domingo. Users have commonly found prices around $621 for the month, but tickets can be as low as $386. Due to multiple factors, prepare for potentially higher prices in December.

What is the cheapest time of day to fly from SDQ to SNA?

It’s typically best to fly out from Santo Domingo to Santa Ana at noon. Doing so could potentially save you 23% on the flight price compared to flying in the morning, which is usually more expensive.

Can I find deals for flights from Santo Domingo to Santa Ana that include hotel bookings?

Yes. In addition to deals on Santo Domingo to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santo Domingo to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santa Ana.

Can I find deals for business class flights from Santo Domingo to Santa Ana?

Yes. Cheapflights offers flight deals from Santo Domingo to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$427+ Flights from Santo Domingo to Santa Ana

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Cheap flight deals from Santo Domingo to Santa Ana

Round-trip from	$427 (SmartFares)
Popular in	December
Cheapest in	January
Average price	$702

From Santo Domingo Las Americas to Santa Ana J. Wayne/Orange Cnty

Search Deals

Highest demand for flights based on searches. 1% potential increase in price ($12 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

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Find flight deals from Santo Domingo to Santa Ana

Cheapest flights from Santo Domingo to Santa Ana
Explore the most affordable flight options available from Santo Domingo to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.

Mon 9/155:00 pmSDQ - SNA

3 stops32h 05mSpirit Airlines

Mon 9/226:45 amSNA - SDQ

3 stops30h 10mSpirit Airlines

Deal found 7/16

$427

Mon 9/153:20 pmSDQ - SNA

2 stops20h 56mUnited Airlines

Mon 9/227:00 pmSNA - SDQ

2 stops13h 55mUnited Airlines

Deal found 7/16

$556

Wed 10/87:00 amSDQ - SNA

2 stops15h 37mAmerican Airlines

Mon 10/137:01 pmSNA - SDQ

2 stops17h 19mAmerican Airlines

Deal found 7/16

$643

Wed 10/83:15 pmSDQ - SNA

1 stop10h 05mDelta

Mon 10/139:20 pmSNA - SDQ

2 stops17h 32mDelta

Deal found 7/17

$730

Best flights from Santo Domingo to Santa Ana
Discover carefully curated flight deals from Santo Domingo to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2025.

Mon 9/155:00 pmSDQ - SNA

3 stops32h 05mSpirit Airlines

Mon 9/226:45 amSNA - SDQ

3 stops30h 10mSpirit Airlines

Deal found 7/16

$427

Mon 9/153:20 pmSDQ - SNA

2 stops20h 56mUnited Airlines

Mon 9/227:00 pmSNA - SDQ

2 stops13h 55mUnited Airlines

Deal found 7/16

$556

Wed 10/87:00 amSDQ - SNA

2 stops15h 37mAmerican Airlines

Mon 10/137:01 pmSNA - SDQ

2 stops17h 19mAmerican Airlines

Deal found 7/16

$643

Wed 10/83:15 pmSDQ - SNA

1 stop10h 05mDelta

Mon 10/139:20 pmSNA - SDQ

1 stop13h 33mDelta

Deal found 7/17

$730

Last-minute flights from Santo Domingo to Santa Ana
Discover last-minute flight deals from Santo Domingo to Santa Ana. Data last updated July 18, 2025 and is based on user searches.

Wed 8/64:52 pmSDQ - SNA

3 stops29h 11mSpirit Airlines

Wed 9/176:45 amSNA - SDQ

3 stops30h 10mSpirit Airlines

Deal found 7/16

$449

Wed 8/64:25 pmSDQ - SNA

2 stops19h 32mAmerican Airlines

Wed 9/1712:50 pmSNA - SDQ

2 stops19h 24mAmerican Airlines

Deal found 7/16

$686

Thu 8/285:45 amSDQ - SNA

1 stop31h 41mUnited Airlines

Wed 9/109:14 pmSNA - SDQ

1 stop13h 56mUnited Airlines

Deal found 7/17

$718

One-way flights from Santo Domingo to Santa Ana
Search for one-way flight options from Santo Domingo to Santa Ana. Find affordable one-way fares based on user searches. Data last updated July 18, 2025.

Mon 12/226:00 amSDQ - SNA

2 stops19h 45mUnited Airlines

Deal found 7/17

$682

Thu 1/13:45 amSDQ - SNA

2 stops16h 40mDelta

Deal found 7/16

$1,998

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoSanta Ana

SDQ - SNA

SDQSNA

Santo Domingo Las Americas

Mon 9/15

5:00 pm-10:05 pm

3 stops32h 05m

Santa Ana J. Wayne/Orange Cnty

Mon 9/22

6:45 am-3:55 pm

3 stops30h 10m

$427

Santo DomingoSanta Ana

SDQ - SNA

SDQSNA

Santo Domingo Las Americas

Mon 9/15

3:20 pm-9:16 am

2 stops20h 56m

Santa Ana J. Wayne/Orange Cnty

Mon 9/22

7:00 pm-11:55 am

2 stops13h 55m

$556

Santo DomingoSanta Ana

SDQ - SNA

SDQSNA

Santo Domingo Las Americas

Wed 10/8

7:00 am-7:37 pm

2 stops15h 37m

Santa Ana J. Wayne/Orange Cnty

Mon 10/13

7:01 pm-3:20 pm

2 stops17h 19m

$643

Santo DomingoSanta Ana

SDQ - SNA

SDQSNA

Santo Domingo Las Americas

Wed 10/8

3:15 pm-10:20 pm

1 stop10h 05m

Santa Ana J. Wayne/Orange Cnty

Mon 10/13

9:20 pm-1:53 pm

1 stop13h 33m

$730

Santo DomingoSanta Ana

SDQ - SNA

SDQSNA

Santo Domingo Las Americas

Mon 12/22

6:00 am-9:45 pm

2 stops19h 45m

$682

Santo DomingoSanta Ana

SDQ - SNA

SDQSNA

Santo Domingo Las Americas

Thu 1/1

3:45 am-4:25 pm

2 stops16h 40m

$1,998

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/17

Best time to book a flight from Santo Domingo to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Santo Domingo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Santa Ana

What is the cheapest month to book a flight from Santo Domingo to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Santa Ana (average of $298). Flying from Santo Domingo to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Santo Domingo to Santa Ana by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,958 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,864 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Spirit Airlines

6.3

Okay

8,035 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Santo Domingo to Santa Ana round-trip?
According to our current data, Spirit Airlines ($427), United Airlines ($556), and American Airlines ($643) offers the cheapest pricing from Santo Domingo to Santa Ana.
Can I find deals for flights from Santo Domingo to Santa Ana that include hotel bookings?
Yes. In addition to deals on Santo Domingo to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santo Domingo to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santa Ana.
Can I find deals for business class flights from Santo Domingo to Santa Ana?
Yes. Cheapflights offers flight deals from Santo Domingo to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santo Domingo to Santa Ana?
Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Santa Ana (average of $298). Flying from Santo Domingo to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Tustin

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Alternative routes for Santo Domingo to Santa Ana

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Burbank car rentals

Other flights to Santa Ana

Top airline flying from Santo Domingo to Santa Ana

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$633	Average$912	FlexibilityNo cancel fee	On-time71%

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$427+ Cheap flights from Santo Domingo (SDQ) to Santa Ana (SNA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santo Domingo to Santa Ana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santo Domingo to Santa Ana

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Santo Domingo to Santa Ana

Cheapest flights from Santo Domingo to Santa AnaExplore the most affordable flight options available from Santo Domingo to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.

Explore the most affordable flight options available from Santo Domingo to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to Santa Ana that are best for you.

Best time to book a flight from Santo Domingo to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Santo Domingo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Santa Ana

What is the cheapest month to book a flight from Santo Domingo to Santa Ana?

Reviews of airlines servicing Santa Ana

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Santo Domingo to Santa Ana by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santo Domingo to Santa Ana round-trip?

Can I find deals for flights from Santo Domingo to Santa Ana that include hotel bookings?

How can I find direct flights from Santo Domingo to Santa Ana?

Can I find deals for business class flights from Santo Domingo to Santa Ana?

What is the cheapest month to book a flight from Santo Domingo to Santa Ana?

Traveling to a place near Santa Ana?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santo Domingo to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Santo Domingo to Santa Ana

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Santo Domingo to Santa Ana
Explore the most affordable flight options available from Santo Domingo to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.