What are the cheapest airlines flying from Santo Domingo to San Diego round-trip?

Spirit Airlines, at $432, was found to be the cheapest airline from Santo Domingo to San Diego.Alternate airlines to your destination round-trip include Delta and American Airlines. Spirit Airlines is currently priced 32% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Santo Domingo to San Diego one-way?

The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $258. However, be on the lookout for offers from American Airlines and Copa Airlines, as they are both options that can get you from Santo Domingo to San Diego for a low price.

What is the cheapest day to fly from Santo Domingo to San Diego?

Travelers seeking maximum savings on their Santo Domingo to San Diego flight should consider departing on Friday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

What is the cheapest day to fly round-trip from Santo Domingo to San Diego?

Thursday is generally a great day to depart. Flying on this day could help you save up to 74%.

What is the cheapest month to fly from Santo Domingo to San Diego?

Our data shows that September tends to be the cheapest month to fly to San Diego from Santo Domingo. Users have commonly found prices around $637 for the month, but tickets can be as low as $501. Due to multiple factors, prepare for potentially higher prices in June.

What is the cheapest time of day to fly from SDQ to SAN?

When flying from Santo Domingo to San Diego, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 23% versus a flight in the morning.

Can I find deals for flights from Santo Domingo to San Diego that include hotel bookings?

Yes. In addition to deals on Santo Domingo to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santo Domingo to San Diego?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to San Diego.

Can I find deals for business class flights from Santo Domingo to San Diego?

Yes. Cheapflights offers flight deals from Santo Domingo to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$228+ Flights from Santo Domingo to San Diego

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Cheap flight deals from Santo Domingo to San Diego

Round-trip from	$432 (SmartFares)
One-way from	$228 (Mytrip)
Popular in	June
Cheapest in	September
Average price	$651

From Santo Domingo Las Americas to San Diego

Search Deals

One-way flight from Santo Domingo Las Americas to San Diego

Search Deals

Highest demand for flights based on searches. 11% potential increase in price ($84 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Santo Domingo to San Diego

Cheapest flights from Santo Domingo to San Diego
Explore the most affordable flight options available from Santo Domingo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Fri 7/1810:55 amSDQ - SAN

2 stops26h 00mSpirit Airlines

Wed 7/303:57 pmSAN - SDQ

2 stops14h 53mSpirit Airlines

Deal found 7/1

$432

Mon 10/277:00 amSDQ - SAN

1 stop19h 41mDelta

Wed 11/197:00 amSAN - SDQ

1 stop14h 16mDelta

Deal found 7/3

$518

Sat 8/165:05 pmSDQ - SAN

3 stops33h 32mMultiple Airlines

Sat 8/306:15 amSAN - SDQ

3 stops36h 30mMultiple Airlines

Deal found 7/3

$524

Tue 12/307:35 pmSDQ - SAN

1 stop19h 44mAmerican Airlines

Mon 1/1211:00 pmSAN - SDQ

1 stop19h 50mAmerican Airlines

Deal found 7/3

$538

Thu 7/316:00 amSDQ - SAN

1 stop15h 55mJetBlue

Mon 8/118:30 pmSAN - SDQ

1 stop16h 29mJetBlue

Deal found 7/3

$670

Wed 10/293:18 pmSDQ - SAN

3 stops32h 10mUnited Airlines

Thu 11/2010:45 pmSAN - SDQ

2 stops12h 21mUnited Airlines

Deal found 7/2

$709

Best flights from Santo Domingo to San Diego
Discover carefully curated flight deals from Santo Domingo to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Fri 7/1810:55 amSDQ - SAN

2 stops26h 00mSpirit Airlines

Wed 7/303:57 pmSAN - SDQ

2 stops14h 53mSpirit Airlines

Deal found 7/1

$432

Mon 10/277:00 amSDQ - SAN

1 stop19h 41mDelta

Wed 11/197:00 amSAN - SDQ

1 stop14h 16mDelta

Deal found 7/3

$518

Sat 8/165:05 pmSDQ - SAN

3 stops33h 32mMultiple Airlines

Sat 8/306:15 amSAN - SDQ

3 stops36h 30mMultiple Airlines

Deal found 7/3

$524

Tue 12/307:35 pmSDQ - SAN

1 stop19h 44mAmerican Airlines

Mon 1/1211:00 pmSAN - SDQ

1 stop19h 50mAmerican Airlines

Deal found 7/3

$538

Thu 7/316:00 amSDQ - SAN

1 stop15h 55mJetBlue

Mon 8/118:30 pmSAN - SDQ

1 stop16h 29mJetBlue

Deal found 7/3

$670

Wed 10/293:18 pmSDQ - SAN

3 stops32h 10mUnited Airlines

Thu 11/2010:45 pmSAN - SDQ

2 stops12h 21mUnited Airlines

Deal found 7/2

$709

Last-minute flights from Santo Domingo to San Diego
Discover last-minute flight deals from Santo Domingo to San Diego. Data last updated July 3, 2025 and is based on user searches.

Tue 7/86:00 amSDQ - SAN

2 stops15h 54mDelta

Tue 7/156:30 amSAN - SDQ

1 stop15h 27mDelta

Deal found 7/2

$636

Tue 7/87:00 amSDQ - SAN

2 stops14h 40mAmerican Airlines

Tue 7/152:27 pmSAN - SDQ

2 stops15h 48mAmerican Airlines

Deal found 7/2

$661

Wed 7/93:02 amSDQ - SAN

1 stop12h 08mJetBlue

Tue 7/159:00 pmSAN - SDQ

2 stops19h 43mJetBlue

Deal found 7/2

$1,091

Thu 7/1010:55 amSDQ - SAN

2 stops26h 00mSpirit Airlines

Tue 7/153:57 pmSAN - SDQ

2 stops14h 53mSpirit Airlines

Deal found 7/2

$620

Thu 7/105:45 amSDQ - SAN

3 stops17h 31mUnited Airlines

Tue 7/158:44 pmSAN - SDQ

2 stops14h 26mUnited Airlines

Deal found 7/2

$1,302

Fri 7/1810:55 amSDQ - SAN

2 stops26h 00mSpirit Airlines

Wed 7/303:57 pmSAN - SDQ

2 stops14h 53mSpirit Airlines

Deal found 7/1

$432

Thu 7/242:00 pmSDQ - SAN

1 stop12h 42mDelta

Mon 7/2810:15 pmSAN - SDQ

2 stops16h 49mDelta

Deal found 7/2

$577

Thu 7/316:00 amSDQ - SAN

1 stop15h 55mJetBlue

Mon 8/118:30 pmSAN - SDQ

1 stop16h 29mJetBlue

Deal found 7/3

$670

Sat 8/165:05 pmSDQ - SAN

3 stops33h 32mMultiple Airlines

Sat 8/306:15 amSAN - SDQ

3 stops36h 30mMultiple Airlines

Deal found 7/3

$524

Thu 8/282:35 pmSDQ - SAN

2 stops12h 36mAmerican Airlines

Sun 8/317:42 pmSAN - SDQ

2 stops14h 53mAmerican Airlines

Deal found 7/3

$542

One-way flights from Santo Domingo to San Diego
Search for one-way flight options from Santo Domingo to San Diego. Find affordable one-way fares based on user searches. Data last updated July 3, 2025.

Mon 8/2510:19 amSDQ - SAN

2 stops24h 02mMultiple Airlines

Deal found 7/3

$228

Thu 8/215:05 pmSDQ - SAN

3 stops41h 16mSpirit Airlines

Deal found 7/2

$258

Thu 8/212:35 pmSDQ - SAN

1 stop10h 19mAmerican Airlines

Deal found 7/2

$280

Sun 7/278:55 amSDQ - SAN

1 stop11h 49mCopa Airlines

Deal found 7/3

$298

Thu 7/243:02 amSDQ - SAN

1 stop12h 08mJetBlue

Deal found 7/3

$381

Fri 7/112:00 pmSDQ - SAN

1 stop12h 42mDelta

Deal found 7/2

$414

Fri 7/255:45 amSDQ - SAN

3 stops17h 31mUnited Airlines

Deal found 7/3

$641

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Fri 7/18

10:55 am-9:55 am

2 stops26h 00m

San Diego

Wed 7/30

3:57 pm-9:50 am

2 stops14h 53m

$432

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Mon 10/27

7:00 am-11:41 pm

1 stop19h 41m

San Diego

Wed 11/19

7:00 am-1:16 am

1 stop14h 16m

$518

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Sat 8/16

5:05 pm-11:37 pm

3 stops33h 32m

San Diego

Sat 8/30

6:15 am-9:45 pm

3 stops36h 30m

$524

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Tue 12/30

7:35 pm-11:19 am

1 stop19h 44m

San Diego

Mon 1/12

11:00 pm-10:50 pm

1 stop19h 50m

$538

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Thu 7/31

6:00 am-6:55 pm

1 stop15h 55m

San Diego

Mon 8/11

8:30 pm-3:59 pm

1 stop16h 29m

$670

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Wed 10/29

3:18 pm-8:28 pm

3 stops32h 10m

San Diego

Thu 11/20

10:45 pm-3:06 pm

2 stops12h 21m

$709

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Mon 8/25

10:19 am-7:21 am

2 stops24h 02m

$228

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Thu 8/21

5:05 pm-7:21 am

3 stops41h 16m

$258

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Thu 8/21

2:35 pm-9:54 pm

1 stop10h 19m

$280

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Sun 7/27

8:55 am-5:44 pm

1 stop11h 49m

$298

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Showing 1-10 of 13 results

Best time to book a flight from Santo Domingo to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santo Domingo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to San Diego

What is the cheapest month to book a flight from Santo Domingo to San Diego?

Currently, August is the cheapest month in which you can book a flight from Santo Domingo to San Diego (average of $286). Flying from Santo Domingo to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santo Domingo to San Diego?

Reviews of airlines servicing San Diego

Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Santo Domingo to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,982 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines

7.5

Good

1,467 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

JetBlue

7.3

Good

2,916 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Santo Domingo to San Diego round-trip?
Spirit Airlines, at $432, was found to be the cheapest airline from Santo Domingo to San Diego.Alternate airlines to your destination round-trip include Delta and American Airlines. Spirit Airlines is currently priced 32% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Santo Domingo to San Diego one-way?
The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $258. However, be on the lookout for offers from American Airlines and Copa Airlines, as they are both options that can get you from Santo Domingo to San Diego for a low price.
Can I find deals for flights from Santo Domingo to San Diego that include hotel bookings?
Yes. In addition to deals on Santo Domingo to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santo Domingo to San Diego?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to San Diego.
Can I find deals for business class flights from Santo Domingo to San Diego?
Yes. Cheapflights offers flight deals from Santo Domingo to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santo Domingo to San Diego?
Currently, August is the cheapest month in which you can book a flight from Santo Domingo to San Diego (average of $286). Flying from Santo Domingo to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Santo Domingo to San Diego

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$500	Average$552	FlexibilityNo cancel fee	On-time71%

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$228+ Cheap flights from Santo Domingo (SDQ) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santo Domingo to San Diego with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santo Domingo to San Diego

Round-trip from

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Popular in

Cheapest in

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Find flight deals from Santo Domingo to San Diego

Cheapest flights from Santo Domingo to San DiegoExplore the most affordable flight options available from Santo Domingo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from Santo Domingo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to San Diego that are best for you.

Best time to book a flight from Santo Domingo to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santo Domingo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to San Diego

What is the cheapest month to book a flight from Santo Domingo to San Diego?

How much does it cost to fly round-trip from Santo Domingo to San Diego?

Reviews of airlines servicing San Diego

Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Santo Domingo to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santo Domingo to San Diego round-trip?

What are the cheapest airlines to fly from Santo Domingo to San Diego one-way?

Can I find deals for flights from Santo Domingo to San Diego that include hotel bookings?

How can I find direct flights from Santo Domingo to San Diego?

Can I find deals for business class flights from Santo Domingo to San Diego?

What is the cheapest month to book a flight from Santo Domingo to San Diego?

Traveling to a place near Santo Domingo?

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Alternative routes for Santo Domingo to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Santo Domingo to San Diego

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Cheapest flights from Santo Domingo to San Diego
Explore the most affordable flight options available from Santo Domingo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.