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$216+ Cheap flights from Myrtle Beach (MYR) to San Francisco Bay Area

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SFO
Nov 9 — Nov 161
Sun 11/9
Sun 11/16
1 adult, Economy
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Find flight deals from Myrtle Beach to San Francisco Bay Area

Cheapest flights from Myrtle Beach to San Francisco Bay Area
Explore the most affordable flight options available from Myrtle Beach to San Francisco Bay Area. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 10, 2025.

This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/612:40 pmMYR - SFO
1 stop8h 40mSouthwest
Thu 11/139:25 pmSFO - MYR
1 stop10h 10mSouthwest
Deal found 10/9$359
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:00 pmMYR - SFO
1 stop8h 04mDelta
Sat 11/159:30 pmSFO - MYR
1 stop9h 20mDelta
Deal found 10/9$373
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:03 amMYR - SFO
2 stops11h 34mAmerican Airlines
Fri 11/1412:27 amSFO - MYR
1 stop7h 06mAmerican Airlines
Deal found 10/9$378
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:45 pmMYR - SFO
2 stops9h 43mAmerican Airlines
Thu 11/1311:15 amSFO - MYR
2 stops9h 40mAmerican Airlines
Deal found 10/9$395
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2411:29 amMYR - SFO
1 stop9h 32mDelta
Mon 12/110:30 pmSFO - MYR
1 stop8h 17mDelta
Deal found 10/8$398
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/209:04 pmMYR - SFO
1 stop18h 01mMultiple Airlines
Wed 10/226:34 amSFO - MYR
2 stops26h 02mMultiple Airlines
Deal found 10/9$400
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2412:06 pmMYR - SFO
2 stops11h 08mAmerican Airlines
Mon 12/111:15 amSFO - MYR
2 stops9h 40mAmerican Airlines
Deal found 10/8$523
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:10 pmMYR - SFO
1 stop8h 00mSouthwest
Mon 10/279:05 pmSFO - MYR
1 stop9h 55mSouthwest
Deal found 10/9$547
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amMYR - STS
2 stops12h 47mAmerican Airlines
Wed 10/294:17 pmSTS - MYR
2 stops20h 41mAmerican Airlines
Deal found 10/7$799
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amMYR - OAK
2 stops8h 50mDelta
Thu 11/134:51 pmOAK - MYR
2 stops13h 59mDelta
Deal found 10/9$868

Cheap flight deals from Myrtle Beach to San Francisco Bay Area

Keep the following information in mind while searching for Myrtle Beach to San Francisco Bay Area flight deals. Data was last updated October 10, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Delta)

One-way from

$216
(Kiwi.com)

Popular in

February

Cheapest in

April

Average price

$394
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
Search Deals
From Myrtle Beach Intl to San Francisco Bay Area
Search Deals
One-way flight from Myrtle Beach Intl to San Francisco Bay Area
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 10, 2025.
Use the filters below to find and compare flights from Myrtle Beach to San Francisco Bay Area that are best for you.

Fly from

Myrtle Beach

Fly to

San Francisco Bay Area

Route

Depart

Return

Price

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 11/6

11:29 am-5:51 pm

1 stop9h 22m

San Francisco

Thu 11/13

10:59 pm-10:34 am

1 stop8h 35m

$359

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 1/28

5:29 pm-10:14 pm

1 stop7h 45m

San Francisco

Sun 2/15

7:50 am-7:13 pm

1 stop8h 23m

$362

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 11/6

6:12 pm-10:50 pm

1 stop7h 38m

San Francisco

Thu 11/13

11:15 am-11:55 pm

2 stops9h 40m

$364

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 11/8

4:00 pm-9:04 pm

1 stop8h 04m

San Francisco

Sat 11/15

9:30 pm-9:50 am

1 stop9h 20m

$373

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 11/6

12:40 pm-9:50 pm

2 stops12h 10m

San Francisco

Thu 11/13

5:30 am-7:30 pm

2 stops11h 00m

$376

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Mon 11/24

11:29 am-6:01 pm

1 stop9h 32m

San Francisco

Mon 12/1

10:30 pm-9:47 am

1 stop8h 17m

$398

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 1/28

11:05 am-6:05 pm

2 stops10h 00m

San Francisco

Sun 2/15

6:25 am-9:05 pm

2 stops11h 40m

$423

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 3/10

2:15 pm-7:50 pm

1 stop8h 35m

San Francisco

Wed 3/11

10:40 pm-10:08 am

1 stop8h 28m

$447

Myrtle BeachOakland

MYR - OAK

MYROAK

Myrtle Beach Intl

Tue 3/10

1:00 pm-11:53 pm

2 stops13h 53m

Oakland

Wed 3/11

1:15 pm-11:35 pm

2 stops31h 20m

$615

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Tue 10/28

6:00 am-3:47 pm

2 stops12h 47m

Santa Rosa Sonoma County

Wed 10/29

4:17 pm-3:58 pm

2 stops20h 41m

$799

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/8

Showing 1-10 of 19 results
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Best time to book a flight from Myrtle Beach to San Francisco Bay Area

Have a flexible travel schedule? Discover the best time to fly to San Francisco Bay Area from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Francisco Bay Area

What is the cheapest month to book a flight from Myrtle Beach to San Francisco Bay Area?

Currently, November is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco Bay Area (average of $148). Flying from Myrtle Beach to San Francisco Bay Area in December is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to XIH?

Find hourly flight availability from Myrtle Beach to San Francisco Bay Area. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 10, 2025.

It’s optimal to fly from Myrtle Beach to San Francisco Bay Area in the afternoon. By choosing this option you can save up to 19% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing San Francisco Bay Area

Get insights into the airlines that provide service to San Francisco Bay Area. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco Bay Area. Reviews last updated October 10, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to San Francisco Bay Area, such as Delta, American Airlines, and Spirit Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,969 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,969 reviews
Delta
8.0
Very good
7,969 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,043 reviews
Delta
8.0
Very good
7,969 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Spirit Airlines
6.3
Okay
8,088 reviews
Delta
8.0
Very good
7,969 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to San Francisco Bay Area. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to San Francisco Bay Area?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to San Francisco Bay Area.

  • How long is the flight from Myrtle Beach to San Francisco Bay Area?

    For as low as $362, Delta can have you in San Francisco Bay Area from Myrtle Beach in 7h 45m. Myrtle Beach and San Francisco Bay Area are separated by a distance of 2431 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Myrtle Beach to San Francisco Bay Area one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $374. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Myrtle Beach to San Francisco Bay Area for a low price.

  • What are the most popular routes from Myrtle Beach to San Francisco Bay Area?

    Most travelers choose Myrtle Beach Intl - San Francisco, Myrtle Beach Intl - Oakland or Myrtle Beach Intl - Santa Rosa Sonoma County when deciding on the best route from Myrtle Beach to San Francisco Bay Area.

  • Can I find deals for flights from Myrtle Beach to San Francisco Bay Area that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to San Francisco Bay Area flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to San Francisco Bay Area?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Francisco Bay Area.

  • Can I find deals for business class flights from Myrtle Beach to San Francisco Bay Area?

    Yes. Cheapflights offers flight deals from Myrtle Beach to San Francisco Bay Area by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to San Francisco Bay Area?

    Currently, November is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco Bay Area (average of $148). Flying from Myrtle Beach to San Francisco Bay Area in December is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Myrtle Beach to San Francisco Bay Area

Discover the top 3 airlines that operate flights from Myrtle Beach to San Francisco Bay Area. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$250Average$428FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$312Average$438FlexibilityNo cancel feeOn-time71%
Spirit AirlinesCheapest$444Average$471FlexibilityNo cancel feeOn-time65%

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