$240+ Cheap flights from Roanoke to San Diego (ROA - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SAN
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to San Diego
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Cheapest flights from Roanoke to San DiegoExplore the most affordable flight options available from Roanoke to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Roanoke to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:52 pm -
1 stop10h 02m
Sat 12/59:25 pm -
1 stop8h 01m
Deal found 8/17![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:51 pm -
1 stop7h 19m
Sat 9/1910:30 pm -
1 stop8h 29m
Deal found 8/16![United Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:51 pm -
1 stop7h 19m
Sat 9/267:41 pm -
2 stops11h 16m
Deal found 8/17![United Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:44 am -
2 stops9h 26m
Tue 9/1511:00 am -
2 stops9h 43m
Deal found 8/20![United Airlines logo]()
$376
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:51 pm -
1 stop7h 50m
Sun 9/2710:30 pm -
1 stop8h 27m
Deal found 8/17![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:26 am -
2 stops10h 00m
Fri 9/2510:30 pm -
1 stop8h 27m
Deal found 8/17![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:49 am -
2 stops11h 01m
Mon 10/1910:30 pm -
1 stop8h 27m
Deal found 8/20![United Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:35 pm -
1 stop9h 12m
Sat 9/266:15 am -
1 stop8h 02m
Deal found 8/20![American Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:00 pm -
1 stop8h 29m
Sat 9/126:18 am -
1 stop7h 51m
Deal found 8/16![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am -
1 stop8h 07m
Sat 8/2910:37 am -
1 stop8h 01m
Deal found 8/18![Delta logo]()
$443
Best flights from Roanoke to San DiegoDiscover carefully curated flight deals from Roanoke to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Roanoke to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:52 pm -
1 stop10h 02m
Sat 12/59:25 pm -
1 stop8h 01m
Deal found 8/16![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:15 am -
1 stop8h 10m
Tue 9/1510:11 am -
2 stops10h 32m
Deal found 8/20![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:32 pm -
1 stop8h 28m
Fri 9/2510:30 pm -
1 stop9h 01m
Deal found 8/18![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:46 pm -
1 stop7h 33m
Tue 9/156:15 am -
2 stops14h 44m
Deal found 8/20![Delta logo]()
$459
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:51 pm -
1 stop7h 19m
Sat 9/2610:30 pm -
1 stop8h 27m
Deal found 8/20![United Airlines logo]()
$461
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/1610:20 am -
2 stops14h 37m
Wed 1/206:30 am -
2 stops11h 09m
Deal found 8/21![United Airlines logo]()
$472
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:26 am -
2 stops10h 00m
Sat 9/197:41 pm -
2 stops11h 18m
Deal found 8/16![United Airlines logo]()
$485
Last-minute flights from Roanoke to San DiegoDiscover last-minute flight deals from Roanoke to San Diego. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to San Diego. Data last updated August 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:35 pm -
1 stop9h 12m
Sat 9/266:15 am -
1 stop8h 02m
Deal found 8/20![American Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am -
1 stop8h 07m
Sat 8/2910:37 am -
1 stop8h 01m
Deal found 8/18![Delta logo]()
$443
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:00 pm -
1 stop8h 29m
Sat 9/126:18 am -
1 stop7h 51m
Deal found 8/16![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
1 stop9h 33m
Mon 9/710:25 pm -
1 stop9h 06m
Deal found 8/19![Delta logo]()
$459
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:44 am -
2 stops9h 26m
Tue 9/1511:00 am -
2 stops9h 43m
Deal found 8/20![United Airlines logo]()
$376
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:51 pm -
1 stop7h 19m
Sat 9/1910:30 pm -
1 stop8h 29m
Deal found 8/16![United Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:51 pm -
1 stop7h 19m
Sat 9/267:41 pm -
2 stops11h 16m
Deal found 8/17![United Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:26 am -
2 stops10h 00m
Fri 9/2510:30 pm -
1 stop8h 27m
Deal found 8/17![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:51 pm -
1 stop7h 50m
Sun 9/2710:30 pm -
1 stop8h 27m
Deal found 8/17![United Airlines logo]()
$379
One-way flights from Roanoke to San DiegoSearch for one-way flight options from Roanoke to San Diego. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Roanoke to San Diego. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:12 am -
3 stops56h 47m
Deal found 8/16![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2710:51 am -
3 stops56h 08m
Deal found 8/16![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:12 am -
3 stops41h 39m
Deal found 8/16![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:51 am -
3 stops56h 07m
Deal found 8/16![Multiple Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops17h 28m
Deal found 8/16![Delta logo]()
$348
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop9h 25m
Deal found 8/16![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:35 am -
2 stops9h 51m
Deal found 8/16![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:47 pm -
1 stop8h 38m
Deal found 8/16![American Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:06 am -
2 stops14h 42m
Deal found 8/16![American Airlines logo]()
$438
Find flight deals from Roanoke to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $351 (American Airlines) |
One-way from | $240 (Kiwi.com) |
Popular in | June |
Cheapest in | September |
Average price | $478 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Roanoke to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Wed 12/2
4:52 pm-11:54 pm
1 stop10h 02m
San Diego
Sat 12/5
9:25 pm-8:26 am
1 stop8h 01m
$351
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Sat 9/12
6:15 am-11:25 am
1 stop8h 10m
San Diego
Tue 9/15
10:11 am-11:43 pm
2 stops10h 32m
$370
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Fri 9/18
3:32 pm-9:00 pm
1 stop8h 28m
San Diego
Fri 9/25
10:30 pm-10:31 am
1 stop9h 01m
$379
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Fri 9/11
4:46 pm-9:19 pm
1 stop7h 33m
San Diego
Tue 9/15
6:15 am-11:59 pm
2 stops14h 44m
$459
Quickest round-trip
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Tue 9/22
5:51 pm-10:10 pm
1 stop7h 19m
San Diego
Sat 9/26
10:30 pm-9:57 am
1 stop8h 27m
$461
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Sat 1/16
10:20 am-9:57 pm
2 stops14h 37m
San Diego
Wed 1/20
6:30 am-8:39 pm
2 stops11h 09m
$472
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Fri 9/18
10:26 am-5:26 pm
2 stops10h 00m
San Diego
Sat 9/19
7:41 pm-9:59 am
2 stops11h 18m
$485
Cheapest one-way
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Thu 9/24
10:51 am-12:00 pm
2 stops28h 09m
$315
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Wed 9/23
6:00 am-8:28 pm
2 stops17h 28m
$348
Quickest one-way
RoanokeSan Diego
ROA Roanoke - SAN San Diego
ROASAN
Roanoke
Fri 9/25
5:51 pm-10:41 pm
1 stop7h 50m
$379
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Roanoke to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Diego in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Roanoke with our price prediction graph.
ROA-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to San Diego
How far ahead should I book a flight from Roanoke to San Diego?
To ensure you get the cheapest price possible for a flight from Roanoke to San Diego, you should look to book at least 53 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Roanoke to San Diego?
Currently, September is the cheapest month in which you can book a flight from Roanoke to San Diego (average of $373). Flying from Roanoke to San Diego in June is currently the most expensive (average of $677). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to San Diego?
Airfare is below average for this route at the moment.
Roanoke to San Diego flights typically cost between $383 and $489 in December.The cheapest round-trip price found within the last 5 days was $351 on American Airlines (Dec 2-Dec 5).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated August 21, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Roanoke to San Diego. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Roanoke to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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La Mesa
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Lemon Grove
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Roanoke and San Diego flights
Browse other Roanoke and San Diego flight options. Last updated on August 21, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
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Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Top 3 airlines flying from Roanoke to San Diego
Discover the top 3 airlines that operate flights from Roanoke to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$488 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$436 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$329 | Average$451 | FlexibilityNo cancel fee | On-timeN/A |