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San Diego

$143+ Cheap flights from Maine to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAN
Jun 12 — Jun 191
Fri 6/12
Fri 6/19
1 adult, Economy
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Cheap flight deals from Maine to San Diego

Cheapest flights from Maine to San Diego
Explore the most affordable flight options available from Maine to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.

This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am
BOS
-
SAN
1 stop8h 08m
United Airlines
Sun 11/810:30 pm
SAN
-
BOS
1 stop7h 54m
United Airlines
Deal found 5/12$247
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:54 pm
BOS
-
SAN
1 stop8h 30m
United Airlines
Tue 6/210:40 pm
SAN
-
BOS
1 stop7h 49m
United Airlines
Deal found 5/12$252
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:07 pm
BOS
-
SAN
1 stop8h 27m
American Airlines
Tue 9/2912:05 pm
SAN
-
BOS
1 stop8h 05m
American Airlines
Deal found 5/10$256
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:45 am
BOS
-
SAN
1 stop8h 04m
United Airlines
Sun 5/3110:30 pm
SAN
-
BOS
1 stop8h 23m
United Airlines
Deal found 5/12$257
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
BOS
-
SAN
1 stop8h 20m
American Airlines
Sat 7/117:15 pm
SAN
-
BOS
1 stop7h 30m
American Airlines
Deal found 5/10$258
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:15 pm
BOS
-
SAN
Nonstop6h 21m
Delta
Wed 6/109:54 pm
SAN
-
BOS
Nonstop5h 36m
Delta
Deal found 5/8$262
This lol.travel deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:40 pm
BOS
-
SAN
Nonstop6h 29m
Alaska Airlines
Sat 6/68:54 pm
SAN
-
BOS
Nonstop5h 50m
Alaska Airlines
Deal found 5/9$264
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:10 pm
BOS
-
SAN
Nonstop6h 21m
Delta
Wed 6/109:54 pm
SAN
-
BOS
Nonstop5h 36m
Delta
Deal found 5/12$267
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:13 pm
BOS
-
SAN
1 stop9h 40m
American Airlines
Sat 5/306:15 am
SAN
-
BOS
1 stop9h 31m
American Airlines
Deal found 5/8$272
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:06 pm
BOS
-
SAN
1 stop8h 47m
American Airlines
Wed 6/1010:45 pm
SAN
-
BOS
1 stop7h 45m
American Airlines
Deal found 5/12$277
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/69:01 am
BOS
-
SAN
1 stop8h 19m
American Airlines
Sat 6/1310:45 pm
SAN
-
BOS
1 stop7h 45m
American Airlines
Deal found 5/11$278
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:26 pm
BOS
-
SAN
1 stop8h 28m
United Airlines
Mon 6/810:40 pm
SAN
-
BOS
1 stop7h 49m
United Airlines
Deal found 5/12$281

Find flight deals from Maine to San Diego

Keep the following information in mind while searching for Maine to San Diego flight deals. Data was last updated May 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$247
(United Airlines)

One-way from

$143
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$527
Provider with most accurate pricing for Portland-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-San Diego flights.
Search Deals
From Maine to San Diego
Search Deals
One-way flight from Maine to San Diego
Search Deals
High demand for flights, 2% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Maine to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Wed 7/22

3:45 pm-11:20 pm

1 stop10h 35m

San Diego

Tue 7/28

2:35 pm-11:05 pm

Nonstop5h 30m

$292

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Tue 5/26

7:20 am-4:21 pm

1 stop12h 01m

San Diego

Thu 5/28

8:54 pm-5:44 am

Nonstop5h 50m

$357

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Fri 7/3

4:33 pm-7:53 pm

Nonstop6h 20m

San Diego

Tue 7/7

5:35 pm-7:40 am

1 stop11h 05m

$357

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Tue 7/21

5:25 am-2:15 pm

2 stops11h 50m

San Diego

Tue 7/28

7:15 am-11:20 pm

2 stops13h 05m

$372

BangorSan Diego

BGR - SAN

BGRSAN

Bangor

Wed 7/1

2:22 pm-9:48 pm

1 stop10h 26m

San Diego

Wed 7/8

9:58 am-10:57 pm

1 stop9h 59m

$375

BangorSan Diego

BGR - SAN

BGRSAN

Bangor

Thu 6/4

4:26 pm-10:39 pm

1 stop9h 13m

San Diego

Sat 6/6

9:59 pm-11:04 am

2 stops10h 05m

$384

BangorSan Diego

BGR - SAN

BGRSAN

Bangor

Mon 11/9

3:52 pm-9:39 pm

1 stop8h 47m

San Diego

Thu 11/12

10:41 pm-12:09 pm

1 stop10h 28m

$389

BangorSan Diego

BGR - SAN

BGRSAN

Bangor

Mon 11/2

4:15 pm-9:57 pm

1 stop8h 42m

San Diego

Thu 11/5

10:51 am-9:54 pm

1 stop8h 03m

$399

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Thu 6/11

2:20 pm-9:05 pm

2 stops9h 45m

San Diego

Thu 6/18

5:10 pm-10:55 am

2 stops14h 45m

$403

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Mon 7/6

4:45 pm-11:25 pm

1 stop9h 40m

San Diego

Mon 7/13

6:30 am-7:20 pm

1 stop9h 50m

$420

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/10

Showing 1-10 of 57 resultsSorted by cheapest first
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Best time to book a flight from Maine to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to San Diego

How far ahead should I book a flight from Maine to San Diego?

The price you pay for your flight from Maine to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Maine to San Diego?

Currently, October is the cheapest month in which you can book a flight from Maine to San Diego (average of $229). Flying from Maine to San Diego in March is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Maine to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Maine to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Maine?

    If you book a flight to San Diego from Maine, you will be flying to San Diego, which is the city’s only airport. San Diego (SAN) is located 2.6 mi from the center of San Diego.

  • How long is the flight from Maine to San Diego?

    A quick flight from Maine to San Diego can take about 10h 26m. Southwest provides one of the quickest options available for as low as $375. There are 2691 mi between Maine and San Diego. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Maine to San Diego one-way?

    The cheapest airlines for a one-way flight from Maine to San Diego are American Airlines ($101), Delta ($156), and United Airlines ($179).

  • What are the most popular routes from Maine to San Diego?

    When deciding which route to take from Maine to San Diego consider Boston Logan Intl - San Diego, Portland - San Diego or Bangor - San Diego as they are the most popular.

  • Can I find deals for flights from Maine to San Diego that include hotel bookings?

    Yes. In addition to deals on Maine to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to San Diego.

  • Can I find deals for business class flights from Maine to San Diego?

    Yes. Cheapflights offers flight deals from Maine to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to San Diego?

    Currently, October is the cheapest month in which you can book a flight from Maine to San Diego (average of $229). Flying from Maine to San Diego in March is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
Poway
La Mesa
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Maine to San Diego

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Top 4 airlines flying from Maine to San Diego

Discover the top 4 airlines that operate flights from Maine to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$311Average$465FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$312Average$519FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$325Average$466FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$365Average$527FlexibilityNo cancel feeOn-time69%

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