$179+ Cheap flights from Maine to San Diego (SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAN
Oct 25 — Nov 11
Round-trip
1 adult, Economy
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Find cheap flights from Maine to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Maine to San Diego
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Cheapest flights from Maine to San DiegoExplore the most affordable flight options available from Maine to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
Explore the most affordable flight options available from Maine to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:45 pm -
1 stop11h 12m
Sat 12/56:15 am -
2 stops12h 12m
Deal found 9/21![Delta logo]()
$346
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:03 am -
1 stop8h 49m
Sat 11/1412:48 pm -
1 stop7h 43m
Deal found 9/23![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:43 am -
1 stop11h 46m
Wed 11/119:25 pm -
1 stop9h 44m
Deal found 9/23![American Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:40 pm -
2 stops11h 40m
Thu 11/1210:40 pm -
2 stops8h 50m
Deal found 9/21![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:39 am -
1 stop11h 50m
Sun 12/139:25 pm -
1 stop9h 44m
Deal found 9/20![American Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:08 pm -
1 stop8h 32m
Mon 11/29:40 pm -
1 stop8h 20m
Deal found 9/22![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:10 pm -
1 stop10h 36m
Wed 11/116:25 am -
2 stops14h 00m
Deal found 9/24![Delta logo]()
$375
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:15 pm -
1 stop10h 31m
Mon 11/210:25 pm -
2 stops11h 47m
Deal found 9/22![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:30 am -
1 stop8h 50m
Sat 10/316:15 am -
1 stop8h 00m
Deal found 9/23![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:23 am -
2 stops14h 10m
Sat 12/126:23 pm -
2 stops13h 16m
Deal found 9/24![United Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:06 pm -
2 stops13h 09m
Mon 12/1410:10 pm -
2 stops10h 16m
Deal found 9/21![Delta logo]()
$381
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:08 pm -
1 stop8h 33m
Sat 10/249:20 pm -
1 stop8h 40m
Deal found 9/22![United Airlines logo]()
$396
Best flights from Maine to San DiegoDiscover carefully curated flight deals from Maine to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
Discover carefully curated flight deals from Maine to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:40 am -
2 stops12h 39m
Mon 12/141:10 pm -
1 stop8h 11m
Deal found 9/21![Delta logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:43 am -
1 stop11h 46m
Wed 11/119:25 pm -
1 stop9h 44m
Deal found 9/24![American Airlines logo]()
$373
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:23 am -
2 stops14h 10m
Sat 12/129:45 pm -
1 stop9h 54m
Deal found 9/24![United Airlines logo]()
$375
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/32:35 pm -
1 stop9h 14m
Wed 3/37:30 pm -
2 stops13h 23m
Deal found 9/20![Delta logo]()
$362
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:15 pm -
1 stop10h 31m
Thu 10/297:59 pm -
2 stops11h 51m
Deal found 9/24![Delta logo]()
$362
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:15 am -
1 stop9h 10m
Thu 10/2210:30 pm -
1 stop9h 10m
Deal found 9/23![United Airlines logo]()
$410
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/32:35 pm -
1 stop9h 14m
Tue 3/26:20 am -
2 stops13h 46m
Deal found 9/20![Delta logo]()
$362
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:15 pm -
1 stop10h 31m
Wed 10/287:59 pm -
2 stops11h 51m
Deal found 9/24![Delta logo]()
$362
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:23 am -
2 stops12h 18m
Sun 12/136:45 pm -
2 stops12h 54m
Deal found 9/21![United Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:55 am -
2 stops10h 19m
Sat 10/316:25 am -
2 stops11h 36m
Deal found 9/23![Delta logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:50 pm -
1 stop8h 29m
Thu 11/196:26 am -
1 stop8h 06m
Deal found 9/20![American Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:00 am -
2 stops14h 40m
Wed 11/1112:37 pm -
3 stops18h 42m
Deal found 9/21![United Airlines logo]()
$487
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/62:35 pm -
2 stops11h 20m
Wed 1/138:00 am -
2 stops12h 06m
Deal found 9/21![Delta logo]()
$368
This Expedia deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:04 am -
1 stop15h 09m
Fri 10/98:15 am -
1 stop8h 58m
Deal found 9/20![Multiple Airlines logo]()
$1,230
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:12 am -
2 stops13h 18m
Tue 12/86:47 pm -
2 stops14h 10m
Deal found 9/21![Delta logo]()
$368
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:00 am -
2 stops12h 24m
Tue 11/39:40 pm -
1 stop9h 39m
Deal found 9/23![United Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:45 pm -
1 stop11h 12m
Sun 12/1310:10 pm -
2 stops15h 01m
Deal found 9/21![Delta logo]()
$395
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:12 am -
2 stops13h 18m
Sun 12/131:10 pm -
1 stop8h 11m
Deal found 9/21![Delta logo]()
$432
Last-minute flights from Maine to San DiegoDiscover last-minute flight deals from Maine to San Diego. Data last updated September 25, 2026 and is based on user searches.
Discover last-minute flight deals from Maine to San Diego. Data last updated September 25, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:10 pm -
1 stop10h 36m
Sun 10/189:45 pm -
2 stops14h 45m
Deal found 9/22![Delta logo]()
$494
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:50 pm -
1 stop8h 29m
Sun 10/189:30 pm -
1 stop9h 52m
Deal found 9/24![American Airlines logo]()
$516
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:08 pm -
1 stop8h 33m
Sat 10/249:20 pm -
1 stop8h 40m
Deal found 9/22![United Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:15 pm -
1 stop10h 31m
Thu 10/297:59 pm -
2 stops11h 51m
Deal found 9/24![Delta logo]()
$362
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:15 pm -
1 stop10h 31m
Wed 10/2810:53 am -
1 stop9h 08m
Deal found 9/24![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:47 pm -
1 stop8h 25m
Tue 10/2710:53 am -
1 stop9h 08m
Deal found 9/24![Delta logo]()
$398
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:47 pm -
1 stop8h 25m
Mon 10/2610:25 pm -
2 stops14h 10m
Deal found 9/24![Delta logo]()
$403
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:25 pm -
2 stops10h 20m
Tue 10/277:00 am -
2 stops10h 35m
Deal found 9/20![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:55 am -
2 stops10h 19m
Sat 10/316:25 am -
2 stops11h 36m
Deal found 9/23![Delta logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:30 am -
1 stop8h 50m
Sat 10/316:15 am -
1 stop8h 00m
Deal found 9/23![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:08 pm -
1 stop8h 32m
Mon 11/29:40 pm -
1 stop8h 20m
Deal found 9/22![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:15 pm -
1 stop10h 31m
Mon 11/210:25 pm -
2 stops11h 47m
Deal found 9/22![Delta logo]()
$377
One-way flights from Maine to San DiegoSearch for one-way flight options from Maine to San Diego. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
Search for one-way flight options from Maine to San Diego. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:15 pm -
1 stop10h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Delta logo]()
$179
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:29 am -
2 stops11h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$184
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:10 pm -
1 stop9h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$194
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:42 pm -
2 stops13h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Delta logo]()
$199
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:30 am -
1 stop8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$213
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:15 pm -
1 stop10h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Delta logo]()
$220
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:04 am -
2 stops12h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Delta logo]()
$225
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:30 am -
1 stop8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:53 pm -
3 stops35h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/83:10 pm -
3 stops31h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$241
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:08 pm -
1 stop8h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$244
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:45 am -
1 stop8h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$249
Find flight deals from Maine to San Diego
Keep the following information in mind while searching for Maine to San Diego flight deals. Data was last updated September 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $346 (Delta) |
One-way from | $179 (Delta) |
Popular in | March |
Cheapest in | February |
Average price | $475 |
Cheapflights Fare Finder
Customize your flight search to find flights from Maine to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
Use the filters below to find and compare flights from Maine to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Tue 1/12
12:50 pm-10:55 pm
2 stops13h 05m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$184
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Thu 11/5
8:29 am-5:17 pm
2 stops11h 48m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$184
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Wed 11/18
6:00 am-4:18 pm
2 stops13h 18m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$184
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Tue 1/12
6:00 am-3:33 pm
2 stops12h 33m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$184
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Thu 11/5
5:10 pm-11:20 pm
1 stop9h 10m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$194
Quickest round-trip
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Fri 11/6
12:42 pm-5:55 pm
1 stop8h 13m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$194
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Fri 1/1
5:41 am-11:02 am
1 stop8h 21m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$220
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Wed 10/14
4:15 pm-11:46 pm
1 stop10h 31m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$220
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Mon 11/9
5:08 pm-10:40 pm
1 stop8h 32m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$244
PortlandSan Diego
PWM Portland - SAN San Diego
PWMSAN
Portland
Tue 11/24
5:50 am-1:43 pm
1 stop10h 53m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$249
Showing 1-10 of 39 resultsSorted by cheapest first
Best time to book a flight from Maine to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Maine with our price prediction graph.
PWM-SAN
BGR-SAN
RKD-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Maine to San Diego
USME-SAN
PWM-SAN
BGR-SAN
RKD-SAN
What is the cheapest month to book a flight from Maine to San Diego?
Currently, January is the cheapest month in which you can book a flight from Maine to San Diego (average of $372). Flying from Maine to San Diego in July is currently the most expensive (average of $685). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Maine to San Diego?
Airfare is below average for this route at the moment.
Maine to San Diego flights typically cost between $417 and $659 in November.The cheapest round-trip price found within the last 5 days was $357 on Delta (Nov 4-Nov 14).
How far ahead should I book a flight from Maine to San Diego?
The price you pay for your flight from Maine to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 60 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Maine to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Coronado
San Ysidro
Poway
La Mesa
Santee
Julian
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Maine to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Maine to San Diego by cabin class
Find flights from Maine to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Maine and San Diego flights
Browse other Maine and San Diego flight options. Last updated on September 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 25, 2026.
Maine to San Diego flights
Consider these flights traveling from Maine to San Diego.
Top 4 airlines flying from Maine to San Diego
Discover the top 4 airlines that operate flights from Maine to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$311 | Average$462 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$333 | Average$565 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$358 | Average$564 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$378 | Average$498 | FlexibilityNo cancel fee | On-time63% |