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San Diego

$134+ Cheap flights from Maine to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAN
Apr 26 — May 31
Sun 4/26
Sun 5/3
1 adult, Economy
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Cheap flight deals from Maine to San Diego

Cheapest flights from Maine to San Diego
Explore the most affordable flight options available from Maine to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
BOS
-
SAN
Nonstop6h 24m
JetBlue
Tue 4/288:35 pm
SAN
-
BOS
Nonstop5h 29m
JetBlue
Deal found 3/24$232
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:44 pm
BOS
-
SAN
Nonstop6h 29m
Delta
Tue 5/129:49 pm
SAN
-
BOS
Nonstop5h 41m
Delta
Deal found 3/26$237
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:10 pm
BOS
-
SAN
1 stop8h 28m
Delta
Tue 4/289:59 pm
SAN
-
BOS
Nonstop5h 31m
Delta
Deal found 3/26$247
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:30 pm
BOS
-
SAN
1 stop10h 10m
Southwest
Tue 6/92:35 pm
SAN
-
BOS
Nonstop5h 25m
Southwest
Deal found 3/22$249
This Alaska Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:56 pm
BOS
-
SAN
Nonstop6h 33m
Alaska Airlines
Wed 5/138:54 pm
SAN
-
BOS
Nonstop5h 50m
Alaska Airlines
Deal found 3/26$252
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:10 pm
BOS
-
SAN
1 stop8h 28m
Delta
Tue 4/219:45 pm
SAN
-
BOS
1 stop8h 49m
Delta
Deal found 3/25$257
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:40 am
BOS
-
SAN
1 stop10h 15m
Southwest
Tue 5/56:20 am
SAN
-
BOS
1 stop7h 55m
Southwest
Deal found 3/22$258
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/44:30 pm
BOS
-
SAN
Nonstop6h 10m
Southwest
Tue 6/92:35 pm
SAN
-
BOS
Nonstop5h 25m
Southwest
Deal found 3/24$261
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:35 am
BOS
-
SAN
2 stops9h 35m
Southwest
Tue 5/1212:00 pm
SAN
-
BOS
1 stop7h 40m
Southwest
Deal found 3/25$262
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:44 pm
BOS
-
SAN
Nonstop6h 29m
Delta
Sat 5/29:59 pm
SAN
-
BOS
Nonstop5h 31m
Delta
Deal found 3/26$263
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:28 pm
PWM
-
SAN
1 stop9h 31m
United Airlines
Wed 4/299:45 pm
SAN
-
PWM
1 stop9h 33m
United Airlines
Deal found 3/25$311
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:43 pm
PWM
-
SAN
1 stop9h 23m
Delta
Tue 5/58:00 am
SAN
-
PWM
2 stops12h 24m
Delta
Deal found 3/25$316

Find flight deals from Maine to San Diego

Keep the following information in mind while searching for Maine to San Diego flight deals. Data was last updated March 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$232
(Cheapflightsfares)

One-way from

$134
(Southwest)

Popular in

December

Cheapest in

September

Average price

$602
Provider with most accurate pricing for Portland-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-San Diego flights.
Search Deals
From Maine to San Diego
Search Deals
One-way flight from Maine to San Diego
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Maine to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Tue 5/12

5:15 pm-8:36 pm

Nonstop6h 21m

San Diego

Tue 5/19

7:11 pm-6:20 am

1 stop8h 09m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Wed 5/6

5:44 pm-9:13 pm

Nonstop6h 29m

San Diego

Mon 5/11

9:49 pm-6:30 am

Nonstop5h 41m

$263

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Thu 6/4

5:15 pm-8:36 pm

Nonstop6h 21m

San Diego

Tue 6/9

7:10 pm-7:35 am

1 stop9h 25m

$273

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Wed 5/13

2:30 pm-9:40 pm

1 stop10h 10m

San Diego

Mon 5/18

10:40 pm-11:00 am

1 stop9h 20m

$296

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Sat 4/25

9:30 am-3:15 pm

1 stop8h 45m

San Diego

Mon 6/1

6:55 pm-5:58 am

1 stop8h 03m

$303

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Sat 6/6

5:10 am-9:50 am

1 stop7h 40m

San Diego

Sun 6/7

2:35 pm-11:00 pm

Nonstop5h 25m

$309

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Tue 5/12

5:15 pm-8:36 pm

Nonstop6h 21m

San Diego

Sun 5/17

9:49 pm-6:30 am

Nonstop5h 41m

$313

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Fri 4/24

3:45 pm-11:10 pm

1 stop10h 25m

San Diego

Sat 5/9

6:25 am-6:45 pm

2 stops9h 20m

$316

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Thu 4/23

5:00 pm-11:06 pm

1 stop9h 06m

San Diego

Wed 5/13

9:49 pm-6:30 am

Nonstop5h 41m

$323

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Thu 5/7

3:23 pm-10:16 pm

1 stop9h 53m

San Diego

Tue 5/12

10:40 pm-10:23 am

1 stop8h 43m

$344

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 56 resultsSorted by cheapest first
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Best time to book a flight from Maine to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to San Diego

What is the cheapest month to book a flight from Maine to San Diego?

Currently, September is the cheapest month in which you can book a flight from Maine to San Diego (average of $277). Flying from Maine to San Diego in March is currently the most expensive (average of $353). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Maine to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Maine to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Maine?

    If you book a flight to San Diego from Maine, you will be flying to San Diego, which is the city’s only airport. San Diego (SAN) is located 2.6 mi from the center of San Diego.

  • How long is the flight from Maine to San Diego?

    A quick flight from Maine to San Diego can take about 6h 21m. Delta provides one of the quickest options available for as low as $247. There are 2581 mi between Maine and San Diego. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Maine to San Diego one-way?

    The cheapest airlines for a one-way flight from Maine to San Diego are American Airlines ($101), Delta ($156), and Southwest ($178).

  • What are the most popular routes from Maine to San Diego?

    When deciding which route to take from Maine to San Diego consider Boston Logan Intl - San Diego, Portland - San Diego or Bangor - San Diego as they are the most popular.

  • Can I find deals for flights from Maine to San Diego that include hotel bookings?

    Yes. In addition to deals on Maine to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to San Diego.

  • Can I find deals for business class flights from Maine to San Diego?

    Yes. Cheapflights offers flight deals from Maine to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to San Diego?

    Currently, September is the cheapest month in which you can book a flight from Maine to San Diego (average of $277). Flying from Maine to San Diego in March is currently the most expensive (average of $353). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Maine to San Diego

Discover the top 4 airlines that operate flights from Maine to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$243Average$440FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$318Average$494FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$325Average$486FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$350Average$503FlexibilityNo cancel feeOn-time69%

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