HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$119+ Cheap flights from Maine to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAN
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Maine to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Maine to San Diego

Keep the following information in mind while searching for Maine to San Diego flight deals. Data was last updated August 14, 2025.

Round-trip from

$240
(Expedia)

One-way from

$119
(Alaska Airlines)

Popular in

April

Cheapest in

January

Average price

$527
From Maine to San Diego
Search Deals
One-way flight from Maine to San Diego
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Maine to San Diego

Cheapest flights from Maine to San Diego
Explore the most affordable flight options available from Maine to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Mytrip deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/612:20 pmBOS - SAN
2 stops14h 14mSpirit Airlines
Mon 9/81:35 pmSAN - BOS
3 stops31h 22mSpirit Airlines
Deal found 8/12$241
This Mytrip deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/306:05 amBOS - SAN
2 stops20h 32mSpirit Airlines
Tue 9/96:15 amSAN - BOS
2 stops13h 32mSpirit Airlines
Deal found 8/14$242
This FlightHub deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/612:20 pmBOS - SAN
2 stops14h 14mSpirit Airlines
Fri 9/1911:59 amSAN - BOS
1 stop7h 48mSpirit Airlines
Deal found 8/12$243
This Orbitz deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/310:34 amBOS - SAN
2 stops16h 03mMultiple Airlines
Sun 9/72:31 pmSAN - BOS
2 stops14h 21mMultiple Airlines
Deal found 8/14$245
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/93:00 pmBOS - SAN
3 stops30h 42mSpirit Airlines
Sat 9/138:24 amSAN - BOS
3 stops23h 49mSpirit Airlines
Deal found 8/13$246
This Alaska Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/194:24 pmBOS - SAN
Nonstop6h 39mAlaska Airlines
Tue 12/25:10 pmSAN - BOS
1 stop20h 56mAlaska Airlines
Deal found 8/14$247
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2710:34 amBOS - SAN
2 stops23h 47mSpirit Airlines
Wed 9/177:47 pmSAN - BOS
2 stops12h 26mSpirit Airlines
Deal found 8/13$248
This Mytrip deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1312:20 pmBOS - SAN
2 stops14h 14mSpirit Airlines
Sat 9/208:24 amSAN - BOS
3 stops23h 49mSpirit Airlines
Deal found 8/14$249
This Mytrip deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/36:30 amBOS - SAN
2 stops20h 07mSpirit Airlines
Thu 9/116:15 amSAN - BOS
2 stops13h 32mSpirit Airlines
Deal found 8/11$250
This Mytrip deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:10 amBOS - SAN
3 stops28h 19mSpirit Airlines
Wed 9/101:35 pmSAN - BOS
3 stops25h 27mSpirit Airlines
Deal found 8/14$251
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/39:30 amBOS - SAN
1 stop8h 33mUnited Airlines
Thu 9/112:11 pmSAN - BOS
1 stop7h 34mUnited Airlines
Deal found 8/13$253
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:00 amPWM - SAN
1 stop8h 36mAmerican Airlines
Tue 9/236:22 amSAN - PWM
1 stop8h 17mAmerican Airlines
Deal found 8/14$283

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Maine to San Diego that are best for you.

Fly from

Maine

Fly to

San Diego

Route

Depart

Return

Price

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Sat 11/15

7:25 am-12:25 pm

1 stop8h 00m

San Diego

Wed 11/19

6:30 am-4:45 pm

1 stop7h 15m

$242

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Wed 12/10

4:20 pm-7:44 pm

Nonstop6h 24m

San Diego

Tue 12/16

7:00 am-11:59 pm

1 stop13h 59m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Wed 10/22

8:01 am-11:18 am

Nonstop6h 17m

San Diego

Wed 11/5

11:37 am-12:20 am

1 stop9h 43m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Sat 11/1

4:24 pm-8:03 pm

Nonstop6h 39m

San Diego

Wed 11/5

6:15 am-12:20 am

1 stop15h 05m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Tue 11/4

10:20 am-5:15 pm

1 stop9h 55m

San Diego

Tue 11/4

8:05 pm-8:15 am

2 stops9h 10m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Wed 11/19

4:24 pm-8:03 pm

Nonstop6h 39m

San Diego

Tue 12/2

9:59 pm-5:06 pm

1 stop16h 07m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Wed 12/10

5:30 am-10:50 am

1 stop8h 20m

San Diego

Tue 12/16

10:30 am-10:45 pm

2 stops9h 15m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Sat 11/1

4:24 pm-8:03 pm

Nonstop6h 39m

San Diego

Tue 11/4

4:30 pm-3:41 pm

1 stop20h 11m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Tue 10/21

8:01 am-11:18 am

Nonstop6h 17m

San Diego

Tue 10/28

8:08 pm-3:41 pm

1 stop16h 33m

$247

BostonSan Diego

BOS - SAN

BOSSAN

Boston Logan Intl

Sat 12/6

4:20 pm-7:44 pm

Nonstop6h 24m

San Diego

Wed 12/10

11:30 am-11:59 pm

1 stop9h 29m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 48 results
1
2
3
...
5

Best time to book a flight from Maine to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to San Diego

What is the cheapest month to book a flight from Maine to San Diego?

Currently, August is the cheapest month in which you can book a flight from Maine to San Diego (average of $286). Flying from Maine to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to SAN?

Find hourly flight availability from Maine to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

When flying from Maine to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Maine to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Maine?

    If you book a flight to San Diego from Maine, you will be flying to San Diego, which is the city’s only airport. San Diego (SAN) is located 2.6 mi from the center of San Diego.

  • What are the cheapest airlines to fly from Maine to San Diego one-way?

    The cheapest airlines for a one-way flight from Maine to San Diego are Alaska Airlines ($119), Frontier ($120), and American Airlines ($163).

  • What are the most popular routes from Maine to San Diego?

    When deciding which route to take from Maine to San Diego consider Boston Logan Intl - San Diego, Portland - San Diego or Bangor - San Diego as they are the most popular.

  • Can I find deals for flights from Maine to San Diego that include hotel bookings?

    Yes. In addition to deals on Maine to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to San Diego.

  • Can I find deals for business class flights from Maine to San Diego?

    Yes. Cheapflights offers flight deals from Maine to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Maine to San Diego (average of $286). Flying from Maine to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
National City
Lemon Grove
Imperial Beach
Alpine

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Maine to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Dallas/Fort Worth to Las Vegas flights
Newark to Los Angeles flights
Newark to Las Vegas flights
O'Hare Intl to Las Vegas flights
John F Kennedy Intl to San Francisco flights
Los Angeles to Las Vegas flights
Dallas/Fort Worth to Los Angeles flights
Seattle to Las Vegas flights
San Francisco to Los Angeles flights
LaGuardia to Los Angeles flights
Seattle to Los Angeles flights
Newark to San Francisco flights
San Jose to Los Angeles flights
Burbank to Las Vegas flights
Atlanta to Las Vegas flights
Los Angeles to San Francisco flights
Hobby to Las Vegas flights
Denver to Las Vegas flights
Santa Ana to Las Vegas flights
Reagan-National to Los Angeles flights
Los Angeles to San Jose flights
Boston to Las Vegas flights
LaGuardia to Las Vegas flights
San Francisco to Ontario flights
Boston to Los Angeles flights
Baltimore to Las Vegas flights
Dulles Intl to Los Angeles flights
O'Hare Intl to Los Angeles flights
Dulles Intl to Las Vegas flights
Ontario to San Francisco flights
Seattle to San Francisco flights
San Francisco to Las Vegas flights
Oakland to Las Vegas flights
Los Angeles to Oakland flights
Fort Lauderdale to Las Vegas flights
Seattle to Ontario flights
Dulles Intl to San Francisco flights
Oakland to Los Angeles flights
Santa Ana to San Francisco flights
LaGuardia to San Francisco flights
San Jose to Las Vegas flights
Dallas/Fort Worth to San Francisco flights
John F Kennedy Intl to Ontario flights
George Bush Intcntl to Las Vegas flights
Orlando to Las Vegas flights
Reagan-National to San Francisco flights
Philadelphia to Las Vegas flights
Reagan-National to Las Vegas flights

Top 4 airlines flying from Maine to San Diego

Discover the top 4 airlines that operate flights from Maine to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$246Average$399FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$308Average$493FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$366Average$518FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$371Average$578FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.