$141+ Cheap flights from Islip, NY to San Diego (ISP - SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — SAN
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Islip to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to San Diego
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Cheapest flights from Islip to San DiegoExplore the most affordable flight options available from Islip to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Islip to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:00 pm -
1 stop26h 52m
Sat 11/146:25 am -
2 stops24h 52m
Deal found 9/17![Multiple Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:10 pm -
1 stop12h 05m
Tue 10/276:15 am -
1 stop10h 45m
Deal found 9/17![Southwest logo]()
$334
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:50 pm -
1 stop8h 10m
Sat 10/249:50 pm -
1 stop9h 30m
Deal found 9/19![Southwest logo]()
$397
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:40 am -
2 stops9h 55m
Fri 10/3011:20 am -
2 stops9h 20m
Deal found 9/19![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:10 pm -
2 stops10h 35m
Fri 10/3010:40 pm -
2 stops10h 15m
Deal found 9/19![Southwest logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:00 pm -
1 stop26h 52m
Sat 11/141:13 pm -
1 stop26h 52m
Deal found 9/17![Breeze Airways logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:00 pm -
1 stop26h 52m
Wed 10/76:25 am -
2 stops24h 52m
Deal found 9/18![Multiple Airlines logo]()
$481
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:35 am -
1 stop10h 45m
Mon 11/236:55 am -
2 stops12h 55m
Deal found 9/20![Southwest logo]()
$530
Best flights from Islip to San DiegoDiscover carefully curated flight deals from Islip to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Islip to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:00 pm -
1 stop26h 52m
Sat 11/146:25 am -
2 stops24h 52m
Deal found 9/17![Multiple Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:45 am -
1 stop8h 25m
Thu 1/216:45 am -
1 stop11h 45m
Deal found 9/16![Southwest logo]()
$328
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:10 pm -
1 stop12h 05m
Tue 10/279:20 am -
2 stops10h 20m
Deal found 9/17![Southwest logo]()
$334
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:40 pm -
1 stop9h 35m
Fri 10/3010:40 pm -
2 stops10h 15m
Deal found 9/19![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:50 pm -
1 stop8h 10m
Sat 10/2410:40 pm -
2 stops8h 40m
Deal found 9/19![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:40 am -
2 stops9h 55m
Fri 10/3011:20 am -
2 stops9h 20m
Deal found 9/19![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:35 am -
1 stop10h 45m
Mon 11/236:55 am -
2 stops12h 55m
Deal found 9/20![Southwest logo]()
$530
Last-minute flights from Islip to San DiegoDiscover last-minute flight deals from Islip to San Diego. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to San Diego. Data last updated September 21, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:00 am -
1 stop11h 15m
Mon 10/510:40 pm -
2 stops10h 30m
Deal found 9/16![Southwest logo]()
$603
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:00 pm -
1 stop26h 52m
Wed 10/76:25 am -
2 stops24h 52m
Deal found 9/18![Multiple Airlines logo]()
$481
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:20 pm -
1 stop8h 05m
Sat 10/109:45 am -
1 stop9h 05m
Deal found 9/20![Southwest logo]()
$617
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:10 pm -
1 stop12h 05m
Tue 10/136:15 am -
1 stop10h 45m
Deal found 9/19![Southwest logo]()
$546
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:50 pm -
1 stop8h 10m
Sat 10/249:50 pm -
1 stop9h 30m
Deal found 9/19![Southwest logo]()
$397
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:10 pm -
1 stop12h 05m
Tue 10/276:15 am -
1 stop10h 45m
Deal found 9/17![Southwest logo]()
$334
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:10 pm -
2 stops10h 35m
Fri 10/3010:40 pm -
2 stops10h 15m
Deal found 9/19![Southwest logo]()
$463
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:40 am -
2 stops9h 55m
Fri 10/3011:20 am -
2 stops9h 20m
Deal found 9/19![Southwest logo]()
$407
One-way flights from Islip to San DiegoSearch for one-way flight options from Islip to San Diego. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Islip to San Diego. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/133:50 pm -
1 stop7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$141
This Lucky2Go deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lucky2Go is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:00 pm -
1 stop10h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$281
This Frontier deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:54 pm -
2 stops24h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$295
This Frontier deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2211:59 am -
2 stops14h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$345
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:54 pm -
2 stops24h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$355
This KAYAK deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:02 pm -
1 stop24h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Breeze Airways logo]()
$360
This KAYAK deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:02 pm -
1 stop24h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Breeze Airways logo]()
$410
This KAYAK deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:00 pm -
1 stop26h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Breeze Airways logo]()
$430
This Frontier deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:55 pm -
2 stops24h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$447
Find flight deals from Islip to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $327 (Kiwi.com) |
One-way from | $141 (Southwest) |
Popular in | December |
Cheapest in | January |
Average price | $443 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Islip to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Wed 1/13
3:50 pm-8:45 pm
1 stop7h 55m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$141
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Sat 10/10
12:00 pm-7:47 pm
1 stop10h 47m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$281
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Mon 11/2
6:54 pm-3:58 pm
2 stops24h 04m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$295
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Sat 11/7
12:00 pm-11:52 am
1 stop26h 52m
San Diego
Sat 11/14
6:25 am-10:17 am
2 stops24h 52m
$327
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Wed 1/13
5:45 am-11:10 am
1 stop8h 25m
San Diego
Thu 1/21
6:45 am-9:30 pm
1 stop11h 45m
$328
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Thu 10/22
3:10 pm-12:15 am
1 stop12h 05m
San Diego
Tue 10/27
9:20 am-10:40 pm
2 stops10h 20m
$334
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Fri 1/22
11:59 am-11:58 pm
2 stops14h 59m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$345
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Mon 11/9
6:54 pm-3:58 pm
2 stops24h 04m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$355
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Mon 11/2
3:02 pm-12:37 pm
1 stop24h 35m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$360
IslipSan Diego
ISP Islip Long Island - SAN San Diego
ISPSAN
Islip Long Island
Mon 10/26
5:40 pm-12:15 am
1 stop9h 35m
San Diego
Fri 10/30
10:40 pm-11:55 am
2 stops10h 15m
$402
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Islip to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to San Diego in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Islip with our price prediction graph.
ISP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 21, 2026.
Peruse reviews from past customers who have flown with Southwest from Islip to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Islip to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Coronado
San Ysidro
Poway
La Mesa
Santee
Julian
Lemon Grove
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Islip and San Diego flights
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Top airline flying from Islip to San Diego
Discover the top airline that operate flights from Islip to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$323 | Average$486 | FlexibilityNo cancel fee | On-time63% |