$234+ Cheap flights from Islip, NY to San Diego (ISP - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — SAN
Jun 17 — Jun 241
Round-trip
1 adult, Economy
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Find cheap flights from Islip to San Diego with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to San Diego
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Best
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Cheapest flights from Islip to San DiegoExplore the most affordable flight options available from Islip to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
Explore the most affordable flight options available from Islip to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am
ISP
- SAN
1 stop9h 45m
Southwest
Tue 10/206:30 am
SAN
- ISP
1 stop10h 05m
Southwest
Deal found 5/14![Southwest logo]()
$408
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:40 pm
ISP
- SAN
2 stops9h 15m
Southwest
Fri 6/2610:40 pm
SAN
- ISP
2 stops9h 55m
Southwest
Deal found 5/15![Southwest logo]()
$441
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:55 am
ISP
- SAN
2 stops13h 40m
Southwest
Thu 7/27:35 pm
SAN
- ISP
2 stops9h 45m
Southwest
Deal found 5/18![Southwest logo]()
$457
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:50 pm
ISP
- SAN
1 stop8h 30m
Southwest
Sun 6/216:30 am
SAN
- ISP
1 stop14h 05m
Southwest
Deal found 5/18![Southwest logo]()
$518
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:57 am
ISP
- SAN
1 stop26h 27m
Breeze Airways
Wed 6/312:29 pm
SAN
- ISP
2 stops27h 40m
Breeze Airways
Deal found 5/15![Breeze Airways logo]()
$561
Best flights from Islip to San DiegoDiscover carefully curated flight deals from Islip to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
Discover carefully curated flight deals from Islip to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:20 am
ISP
- SAN
2 stops9h 30m
Southwest
Tue 10/206:30 am
SAN
- ISP
1 stop10h 05m
Southwest
Deal found 5/14![Southwest logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:57 am
ISP
- SAN
1 stop26h 27m
Breeze Airways
Wed 6/312:29 pm
SAN
- ISP
2 stops27h 40m
Breeze Airways
Deal found 5/15![Breeze Airways logo]()
$561
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:00 am
ISP
- SAN
2 stops28h 33m
Multiple Airlines
Wed 6/31:22 pm
SAN
- ISP
1 stop26h 47m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$709
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:40 pm
ISP
- SAN
2 stops9h 15m
Southwest
Fri 6/2610:40 pm
SAN
- ISP
2 stops9h 55m
Southwest
Deal found 5/15![Southwest logo]()
$441
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:40 pm
ISP
- SAN
1 stop9h 45m
Southwest
Thu 7/27:35 pm
SAN
- ISP
2 stops9h 45m
Southwest
Deal found 5/18![Southwest logo]()
$508
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:50 pm
ISP
- SAN
1 stop8h 30m
Southwest
Sun 6/216:30 am
SAN
- ISP
1 stop14h 05m
Southwest
Deal found 5/18![Southwest logo]()
$518
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:30 am
ISP
- SAN
2 stops12h 15m
Southwest
Wed 6/39:15 am
SAN
- ISP
2 stops9h 55m
Southwest
Deal found 5/15![Southwest logo]()
$597
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:30 pm
ISP
- SAN
1 stop8h 30m
Southwest
Wed 6/310:10 pm
SAN
- ISP
1 stop9h 20m
Southwest
Deal found 5/16![Southwest logo]()
$827
Last-minute flights from Islip to San DiegoDiscover last-minute flight deals from Islip to San Diego. Data last updated May 18, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to San Diego. Data last updated May 18, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:57 am
ISP
- SAN
1 stop26h 27m
Breeze Airways
Wed 6/312:29 pm
SAN
- ISP
2 stops27h 40m
Breeze Airways
Deal found 5/15![Breeze Airways logo]()
$561
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:30 am
ISP
- SAN
2 stops12h 15m
Southwest
Wed 6/39:15 am
SAN
- ISP
2 stops9h 55m
Southwest
Deal found 5/15![Southwest logo]()
$597
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:50 pm
ISP
- SAN
1 stop8h 30m
Southwest
Sun 6/216:30 am
SAN
- ISP
1 stop14h 05m
Southwest
Deal found 5/18![Southwest logo]()
$518
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:40 pm
ISP
- SAN
2 stops9h 15m
Southwest
Fri 6/2610:40 pm
SAN
- ISP
2 stops9h 55m
Southwest
Deal found 5/15![Southwest logo]()
$441
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:55 am
ISP
- SAN
2 stops13h 40m
Southwest
Thu 7/27:35 pm
SAN
- ISP
2 stops9h 45m
Southwest
Deal found 5/18![Southwest logo]()
$457
One-way flights from Islip to San DiegoSearch for one-way flight options from Islip to San Diego. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
Search for one-way flight options from Islip to San Diego. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:35 pm
ISP
- SAN
1 stop7h 40m
Southwest
Deal found 5/14![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1111:57 am
ISP
- SAN
3 stops34h 01m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$310
This KAYAK deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:56 am
ISP
- SAN
1 stop27h 37m
Breeze Airways
Deal found 5/18![Breeze Airways logo]()
$400
This KAYAK deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:57 am
ISP
- SAN
1 stop26h 27m
Breeze Airways
Deal found 5/16![Breeze Airways logo]()
$410
This KAYAK deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:28 pm
ISP
- SAN
1 stop24h 41m
Breeze Airways
Deal found 5/18![Breeze Airways logo]()
$420
This KAYAK deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1111:57 am
ISP
- SAN
1 stop26h 27m
Breeze Airways
Deal found 5/18![Breeze Airways logo]()
$440
This KAYAK deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:57 am
ISP
- SAN
1 stop26h 27m
Breeze Airways
Deal found 5/15![Breeze Airways logo]()
$460
This KAYAK deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:56 am
ISP
- SAN
1 stop27h 37m
Breeze Airways
Deal found 5/18![Breeze Airways logo]()
$470
This KAYAK deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:49 pm
ISP
- SAN
1 stop19h 31m
Breeze Airways
Deal found 5/18![Breeze Airways logo]()
$490
This KAYAK deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:49 pm
ISP
- SAN
1 stop19h 31m
Breeze Airways
Deal found 5/17![Breeze Airways logo]()
$500
Find flight deals from Islip to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $408 (Southwest) |
One-way from | $234 (Southwest) |
Popular in | December |
Cheapest in | September |
Average price | $427 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Islip to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Thu 10/15
10:20 am-4:50 pm
2 stops9h 30m
San Diego
Tue 10/20
6:30 am-7:35 pm
1 stop10h 05m
$413
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Tue 6/23
4:40 pm-10:55 pm
2 stops9h 15m
San Diego
Fri 6/26
10:40 pm-11:35 am
2 stops9h 55m
$441
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Wed 6/24
4:40 pm-11:25 pm
1 stop9h 45m
San Diego
Thu 7/2
7:35 pm-8:20 am
2 stops9h 45m
$508
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Mon 6/15
5:50 pm-11:20 pm
1 stop8h 30m
San Diego
Sun 6/21
6:30 am-11:35 pm
1 stop14h 05m
$518
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Sat 5/30
11:57 am-11:24 am
1 stop26h 27m
San Diego
Wed 6/3
12:29 pm-7:09 pm
2 stops27h 40m
$561
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Sat 5/30
5:30 am-2:45 pm
2 stops12h 15m
San Diego
Wed 6/3
9:15 am-10:10 pm
2 stops9h 55m
$597
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Fri 5/29
11:00 am-12:33 pm
2 stops28h 33m
San Diego
Wed 6/3
1:22 pm-7:09 pm
1 stop26h 47m
$709
Quickest round-trip
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Fri 5/29
4:30 pm-10:00 pm
1 stop8h 30m
San Diego
Wed 6/3
10:10 pm-10:30 am
1 stop9h 20m
$827
Cheapest one-way
Quickest one-way
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Sat 7/11
5:35 pm-10:15 pm
1 stop7h 40m
$234
IslipSan Diego
ISP - SAN
ISPSAN
Islip Long Island
Sat 7/11
11:57 am-6:58 pm
3 stops34h 01m
$310
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Islip to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to San Diego in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Islip with our price prediction graph.
ISP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated May 18, 2026.
Peruse reviews from past customers who have flown with Southwest from Islip to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Islip to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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Julian
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Islip and San Diego flights
Browse other Islip and San Diego flight options. Last updated on May 18, 2026.
Other flights from Islip
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Popular flight searches
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Other flights to San Diego
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Top airline flying from Islip to San Diego
Discover the top airline that operate flights from Islip to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$350 | Average$558 | FlexibilityNo cancel fee | On-time63% |