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$444+ Cheap flights from La Crosse to San Diego (LSE - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — SAN
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from La Crosse to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$444
(American Airlines)
From La Crosse to San Diego
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Find flight deals from La Crosse to San Diego

Best flights from La Crosse to San Diego
Discover carefully curated flight deals from La Crosse to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/106:06 amLSE - SAN
1 stop8h 10mAmerican Airlines
Wed 1/141:35 pmSAN - LSE
1 stop6h 57mAmerican Airlines
Deal found 9/10$444

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from La Crosse to San Diego that are best for you.

Fly from

La Crosse

Fly to

San Diego

Route

Depart

Return

Price

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Sat 1/10

6:06 am-12:16 pm

1 stop8h 10m

San Diego

Wed 1/14

1:35 pm-10:32 pm

1 stop6h 57m

$444

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 10/1

9:50 am-2:03 pm

1 stop6h 13m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from La Crosse to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to San Diego

What is the cheapest month to book a flight from La Crosse to San Diego?

Currently, August is the cheapest month in which you can book a flight from La Crosse to San Diego (average of $286). Flying from La Crosse to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with American Airlines from La Crosse to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.4

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.4

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.

Related info for your journey

Find useful and relevant information for your journey from La Crosse to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from La Crosse to San Diego?

    For as low as $444, American Airlines can have you in San Diego from La Crosse in 8h 10m. La Crosse and San Diego are separated by a distance of 1593 mi.

  • What is the cheapest airline to fly from La Crosse to San Diego round-trip?

    According to our current data, American Airlines ($534), offers the cheapest pricing from La Crosse to San Diego.

  • Can I find deals for flights from La Crosse to San Diego that include hotel bookings?

    Yes. In addition to deals on La Crosse to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to San Diego.

  • Can I find deals for business class flights from La Crosse to San Diego?

    Yes. Cheapflights offers flight deals from La Crosse to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to San Diego?

    Currently, August is the cheapest month in which you can book a flight from La Crosse to San Diego (average of $286). Flying from La Crosse to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

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Top airline flying from La Crosse to San Diego

Discover the top airline that operate flights from La Crosse to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$534Average$610FlexibilityNo cancel feeOn-time71%

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