$473+ Cheap flights from La Crosse to San Diego (LSE - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — SAN
Jan 14 — Jan 211
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from La Crosse to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to San Diego
Cheapest flights from La Crosse to San DiegoExplore the most affordable flight options available from La Crosse to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.
Explore the most affordable flight options available from La Crosse to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:09 amLSE - SAN
2 stops11h 03mAmerican Airlines
Fri 1/23:03 pmSAN - LSE
1 stop6h 35mAmerican Airlines
Deal found 12/14![American Airlines logo]()
$953
Find flight deals from La Crosse to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 15, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $577 (American Airlines) |
One-way from | $473 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from La Crosse to San Diego that are best for you.
Fly from
La Crosse
Fly to
San Diego
Route
Depart
Return
Price
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Fri 3/13
6:00 am-12:43 pm
1 stop8h 43m
San Diego
Thu 3/26
6:20 am-5:58 pm
2 stops9h 38m
$830
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Wed 12/31
10:09 am-7:12 pm
2 stops11h 03m
San Diego
Fri 1/2
3:03 pm-11:38 pm
1 stop6h 35m
$953
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Mon 3/23
6:28 pm-12:43 pm
1 stop20h 15m
San Diego
Sat 3/28
1:34 pm-11:36 pm
1 stop8h 02m
$980
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Wed 1/7
5:08 pm-10:26 pm
1 stop7h 18m
$473
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Tue 1/6
5:08 pm-10:26 pm
1 stop7h 18m
$473
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Thu 1/8
5:08 pm-10:26 pm
1 stop7h 18m
$515
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Fri 1/2
6:00 am-12:23 pm
1 stop8h 23m
$515
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Mon 1/5
6:00 am-12:23 pm
1 stop8h 23m
$515
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Sun 1/4
5:45 am-3:24 pm
2 stops11h 39m
$521
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Sat 1/3
6:00 am-3:24 pm
2 stops11h 24m
$557
Compare providers for flights from La Crosse to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to San Diego in December.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on La Crosse-San Diego flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on La Crosse-San Diego flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from La Crosse-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from La Crosse to San Diego
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated December 15, 2025.
Peruse reviews from past customers who have flown with American Airlines from La Crosse to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Boarding
7.5
Crew
8.0
Food
6.5
Entertainment
6.9
Overall
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2024
LHR - SAN
Comfort
7.2
Boarding
7.5
Crew
8.0
Food
6.5
Entertainment
6.9
Overall
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2024
LHR - SAN
Related info for your journey
Find useful and relevant information for your journey from La Crosse to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
Julian
National City
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for La Crosse to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from La Crosse to San Diego
Discover the top airline that operate flights from La Crosse to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$474 | Average$600 | FlexibilityNo cancel fee | On-time71% |