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$320+ Cheap flights from Gainesville to San Diego (GNV - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/2. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — SAN
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Gainesville to San Diego

Best flights from Gainesville to San Diego
Discover carefully curated flight deals from Gainesville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/136:00 amGNV - SAN
1 stop6h 58mDelta
Sun 1/181:26 pmSAN - GNV
1 stop6h 03mDelta
Deal found 12/10$321
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/86:00 amGNV - SAN
2 stops11h 14mAmerican Airlines
Sat 1/171:27 pmSAN - GNV
1 stop7h 30mAmerican Airlines
Deal found 12/9$403
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/86:27 pmGNV - SAN
1 stop7h 18mDelta
Sat 1/178:05 amSAN - GNV
1 stop6h 33mDelta
Deal found 12/9$321
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/136:00 amGNV - SAN
2 stops11h 14mAmerican Airlines
Sun 1/1812:40 pmSAN - GNV
1 stop7h 50mAmerican Airlines
Deal found 12/10$403
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/181:35 pmGNV - SAN
1 stop10h 01mDelta
Sun 3/229:25 pmSAN - GNV
1 stop9h 01mDelta
Deal found 12/11$448
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/164:30 pmGNV - SAN
1 stop7h 11mAmerican Airlines
Mon 1/1910:50 amSAN - GNV
2 stops10h 07mAmerican Airlines
Deal found 12/10$480
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:35 pmGNV - SAN
1 stop10h 01mDelta
Sun 3/229:25 pmSAN - GNV
1 stop9h 01mDelta
Deal found 12/11$448
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/166:27 pmGNV - SAN
1 stop7h 18mDelta
Mon 1/1910:30 pmSAN - GNV
1 stop7h 54mDelta
Deal found 12/10$450
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/145:30 pmGNV - SAN
2 stops18h 47mDelta
Fri 3/209:25 pmSAN - GNV
1 stop9h 01mDelta
Deal found 12/11$503
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/145:30 pmGNV - SAN
2 stops18h 47mDelta
Sun 3/229:25 pmSAN - GNV
1 stop9h 01mDelta
Deal found 12/11$519

Find flight deals from Gainesville to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$321
(Delta)

One-way from

$320
(Delta)

Popular in

March

Cheapest in

July

Average price

$488
Provider with most accurate pricing for Gainesville Regional-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-San Diego flights.
Search Deals
From Gainesville Regional to San Diego
Search Deals
One-way flight from Gainesville Regional to San Diego
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Gainesville to San Diego that are best for you.

Fly from

Gainesville

Fly to

San Diego

Route

Depart

Return

Price

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Tue 1/13

6:00 am-9:58 am

1 stop6h 58m

San Diego

Sun 1/18

1:26 pm-10:29 pm

1 stop6h 03m

$321

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Thu 1/8

6:27 pm-10:45 pm

1 stop7h 18m

San Diego

Sat 1/17

8:05 am-5:38 pm

1 stop6h 33m

$321

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Thu 1/8

6:00 am-2:14 pm

2 stops11h 14m

San Diego

Sat 1/17

1:27 pm-11:57 pm

1 stop7h 30m

$403

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Tue 1/13

6:00 am-2:14 pm

2 stops11h 14m

San Diego

Sun 1/18

12:40 pm-11:30 pm

1 stop7h 50m

$403

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Wed 3/18

1:35 pm-8:36 pm

1 stop10h 01m

San Diego

Sun 3/22

9:25 pm-9:26 am

1 stop9h 01m

$448

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Tue 3/17

1:35 pm-8:36 pm

1 stop10h 01m

San Diego

Sun 3/22

9:25 pm-9:26 am

1 stop9h 01m

$448

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Fri 1/16

6:27 pm-10:45 pm

1 stop7h 18m

San Diego

Mon 1/19

10:30 pm-9:24 am

1 stop7h 54m

$450

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Fri 1/16

4:30 pm-8:41 pm

1 stop7h 11m

San Diego

Mon 1/19

10:50 am-11:57 pm

2 stops10h 07m

$480

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Sat 3/14

5:30 pm-9:17 am

2 stops18h 47m

San Diego

Fri 3/20

9:25 pm-9:26 am

1 stop9h 01m

$503

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Sat 3/14

5:30 pm-9:17 am

2 stops18h 47m

San Diego

Sun 3/22

9:25 pm-9:26 am

1 stop9h 01m

$519

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 16 results
1
2

Compare providers for flights from Gainesville to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to San Diego in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-San Diego flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Gainesville-San Diego flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Gainesville-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to San Diego

What is the cheapest month to book a flight from Gainesville to San Diego?

Currently, June is the cheapest month in which you can book a flight from Gainesville to San Diego (average of $99). Flying from Gainesville to San Diego in September is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from Gainesville to San Diego, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Gainesville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to San Diego?

    There are many flights that can get you from Gainesville to San Diego in 6h 58m. Fly via Delta or American Airlines to get the fastest option. Gainesville and San Diego are separated by a distance of 2064 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Gainesville to San Diego round-trip?

    Cheapflights users have booked flights from Gainesville to San Diego round-trip from $388. Another airline that can offer you cheap pricing is Delta. American Airlines is priced at 34% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Gainesville to San Diego that include hotel bookings?

    Yes. In addition to deals on Gainesville to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to San Diego.

  • Can I find deals for business class flights from Gainesville to San Diego?

    Yes. Cheapflights offers flight deals from Gainesville to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to San Diego?

    Currently, June is the cheapest month in which you can book a flight from Gainesville to San Diego (average of $99). Flying from Gainesville to San Diego in September is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
Julian
National City

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Top 2 airlines flying from Gainesville to San Diego

Discover the top 2 airlines that operate flights from Gainesville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$388Average$488FlexibilityNo cancel feeOn-time71%
DeltaCheapest$474Average$616FlexibilityNo cancel feeOn-timeN/A

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