HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$389+ Cheap flights from Gainesville to San Diego (GNV - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — SAN
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Gainesville to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Gainesville to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$389
(American Airlines)

Popular in

March

Cheapest in

July

Average price

$496
From Gainesville Regional to San Diego
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Gainesville to San Diego

Cheapest flights from Gainesville to San Diego
Explore the most affordable flight options available from Gainesville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amGNV - SAN
1 stop8h 42mAmerican Airlines
Wed 12/1010:23 pmSAN - GNV
1 stop9h 33mAmerican Airlines
Deal found 9/10$389
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:07 pmGNV - SAN
1 stop7h 07mDelta
Sun 10/269:48 pmSAN - GNV
1 stop8h 38mDelta
Deal found 9/10$432
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/223:02 pmGNV - SAN
2 stops10h 22mAmerican Airlines
Sun 10/2610:31 pmSAN - GNV
1 stop7h 22mAmerican Airlines
Deal found 9/10$491
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/272:10 pmGNV - SAN
1 stop9h 16mDelta
Sun 9/289:50 pmSAN - GNV
1 stop8h 35mDelta
Deal found 9/10$516
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2710:52 amGNV - SAN
2 stops11h 32mAmerican Airlines
Sun 9/2810:42 pmSAN - GNV
1 stop8h 39mAmerican Airlines
Deal found 9/10$564
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/254:01 pmGNV - SAN
1 stop7h 24mDelta
Mon 9/2910:30 pmSAN - GNV
1 stop7h 55mDelta
Deal found 9/10$567
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:25 amGNV - SAN
1 stop7h 29mAmerican Airlines
Mon 9/2910:42 amSAN - GNV
2 stops10h 17mAmerican Airlines
Deal found 9/10$623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Gainesville to San Diego that are best for you.

Fly from

Gainesville

Fly to

San Diego

Route

Depart

Return

Price

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Wed 12/3

6:00 am-11:42 am

1 stop8h 42m

San Diego

Wed 12/10

10:23 pm-10:56 am

1 stop9h 33m

$389

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Wed 10/8

7:07 pm-11:14 pm

1 stop7h 07m

San Diego

Sat 10/11

10:30 pm-9:26 am

1 stop7h 56m

$427

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Wed 10/22

7:07 pm-11:14 pm

1 stop7h 07m

San Diego

Sun 10/26

9:48 pm-9:26 am

1 stop8h 38m

$432

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Wed 10/8

7:11 am-3:30 pm

2 stops11h 19m

San Diego

Sat 10/11

12:30 pm-11:55 pm

1 stop8h 25m

$463

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Wed 10/22

3:02 pm-10:24 pm

2 stops10h 22m

San Diego

Sun 10/26

10:31 pm-8:53 am

1 stop7h 22m

$491

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Sat 9/27

2:10 pm-8:26 pm

1 stop9h 16m

San Diego

Sun 9/28

9:50 pm-9:25 am

1 stop8h 35m

$516

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Thu 9/25

4:01 pm-8:25 pm

1 stop7h 24m

San Diego

Mon 9/29

10:30 pm-9:25 am

1 stop7h 55m

$567

GainesvilleSan Diego

GNV - SAN

GNVSAN

Gainesville Regional

Thu 9/25

6:25 am-10:54 am

1 stop7h 29m

San Diego

Mon 9/29

10:42 am-11:59 pm

2 stops10h 17m

$623

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Gainesville to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to San Diego

What is the cheapest month to book a flight from Gainesville to San Diego?

Currently, August is the cheapest month in which you can book a flight from Gainesville to San Diego (average of $286). Flying from Gainesville to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Gainesville to San Diego, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Gainesville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to San Diego?

    There are many flights that can get you from Gainesville to San Diego in 7h 07m. Fly via American Airlines or Delta to get the fastest option. Gainesville and San Diego are separated by a distance of 2064 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Gainesville to San Diego round-trip?

    Cheapflights users have booked flights from Gainesville to San Diego round-trip from $431. Another airline that can offer you cheap pricing is Delta. American Airlines is priced at 26% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Gainesville to San Diego that include hotel bookings?

    Yes. In addition to deals on Gainesville to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to San Diego.

  • Can I find deals for business class flights from Gainesville to San Diego?

    Yes. Cheapflights offers flight deals from Gainesville to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Gainesville to San Diego (average of $286). Flying from Gainesville to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Gainesville to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to Las Vegas flights
Fort Lauderdale to Las Vegas flights
Tampa to Las Vegas flights
Miami to Los Angeles flights
Miami to Las Vegas flights
Orlando to Los Angeles flights
Fort Lauderdale to Los Angeles flights
Tampa to Los Angeles flights
Orlando to San Francisco flights
Fort Lauderdale to San Francisco flights
Miami to San Francisco flights
Tampa to San Diego flights
Tampa to San Francisco flights
Miami to Ontario flights
West Palm Beach to Las Vegas flights
Jacksonville to Las Vegas flights
Fort Lauderdale to Burbank flights
Orlando to San Diego flights
Fort Lauderdale to Santa Ana flights
Orlando to Ontario flights
Orlando to Santa Ana flights
Miami to San Diego flights
Tampa to Ontario flights
Tampa to Santa Ana flights
Miami to Santa Ana flights
Fort Lauderdale to Ontario flights
Miami to Burbank flights
Fort Myers to Las Vegas flights
Pensacola to Las Vegas flights
Fort Lauderdale to San Diego flights
Orlando to Burbank flights
Jacksonville to Los Angeles flights
Jacksonville to San Francisco flights
Sarasota to Las Vegas flights
West Palm Beach to Los Angeles flights
Fort Myers to Los Angeles flights
Jacksonville to Ontario flights
Valparaiso to Las Vegas flights
West Palm Beach to San Francisco flights
Pensacola to Los Angeles flights
Gainesville to Las Vegas flights
Orlando to Sacramento flights
Tampa to Burbank flights
Orlando to Oakland flights
Panama City to Las Vegas flights
Pensacola to Ontario flights
Orlando Sanford Intl to Las Vegas flights
Jacksonville to San Diego flights
Miami to San Jose flights
Gainesville to Ontario flights

Top 2 airlines flying from Gainesville to San Diego

Discover the top 2 airlines that operate flights from Gainesville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$431Average$596FlexibilityNo cancel feeOn-time71%
DeltaCheapest$474Average$692FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.