$339+ Cheap flights from Gainesville to San Diego (GNV - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — SAN
Apr 15 — Apr 221
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Gainesville to San Diego
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Best
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Cheapest flights from Gainesville to San DiegoExplore the most affordable flight options available from Gainesville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.
Explore the most affordable flight options available from Gainesville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:03 pm
GNV
- SAN
1 stop7h 22m
Delta
Tue 4/2110:30 pm
SAN
- GNV
1 stop7h 54m
Delta
Deal found 3/15![Delta logo]()
$492
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/244:59 pm
GNV
- SAN
1 stop8h 59m
Delta
Fri 7/3110:40 pm
SAN
- GNV
1 stop7h 43m
Delta
Deal found 3/13![Delta logo]()
$535
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/284:15 pm
GNV
- SAN
1 stop7h 22m
American Airlines
Wed 4/110:00 pm
SAN
- GNV
1 stop9h 59m
American Airlines
Deal found 3/13![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
GNV
- SAN
1 stop9h 10m
American Airlines
Sun 4/56:15 am
SAN
- GNV
1 stop6h 30m
American Airlines
Deal found 3/12![American Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:00 am
GNV
- SAN
1 stop8h 12m
American Airlines
Sat 7/187:15 am
SAN
- GNV
1 stop6h 29m
American Airlines
Deal found 3/12![American Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
GNV
- SAN
1 stop9h 10m
American Airlines
Sat 4/117:15 am
SAN
- GNV
1 stop6h 29m
American Airlines
Deal found 3/15![American Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:15 pm
GNV
- SAN
1 stop7h 22m
American Airlines
Mon 3/2310:43 pm
SAN
- GNV
1 stop9h 32m
American Airlines
Deal found 3/15![American Airlines logo]()
$663
Best flights from Gainesville to San DiegoDiscover carefully curated flight deals from Gainesville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 16, 2026.
Discover carefully curated flight deals from Gainesville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 16, 2026.
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:03 pm
GNV
- SAN
1 stop7h 22m
Delta
Tue 4/2110:30 pm
SAN
- GNV
1 stop7h 54m
Delta
Deal found 3/15![Delta logo]()
$492
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
GNV
- SAN
1 stop9h 10m
American Airlines
Sat 4/117:15 am
SAN
- GNV
1 stop6h 29m
American Airlines
Deal found 3/15![American Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
GNV
- SAN
1 stop8h 53m
American Airlines
Tue 4/219:12 am
SAN
- GNV
2 stops9h 32m
American Airlines
Deal found 3/12![American Airlines logo]()
$682
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
GNV
- SAN
1 stop6h 52m
Delta
Sun 3/299:55 pm
SAN
- GNV
1 stop8h 34m
Delta
Deal found 3/12![Delta logo]()
$773
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:17 am
GNV
- SAN
1 stop8h 29m
American Airlines
Fri 4/310:49 am
SAN
- GNV
1 stop9h 11m
American Airlines
Deal found 3/15![American Airlines logo]()
$741
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:17 am
GNV
- SAN
2 stops11h 43m
American Airlines
Wed 4/16:24 am
SAN
- GNV
2 stops9h 56m
American Airlines
Deal found 3/13![American Airlines logo]()
$755
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:15 pm
GNV
- SAN
1 stop9h 08m
American Airlines
Sat 3/216:24 am
SAN
- GNV
2 stops9h 30m
American Airlines
Deal found 3/13![American Airlines logo]()
$870
Last-minute flights from Gainesville to San DiegoDiscover last-minute flight deals from Gainesville to San Diego. Data last updated March 16, 2026 and is based on user searches.
Discover last-minute flight deals from Gainesville to San Diego. Data last updated March 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:15 pm
GNV
- SAN
1 stop7h 22m
American Airlines
Mon 3/2310:43 pm
SAN
- GNV
1 stop9h 32m
American Airlines
Deal found 3/15![American Airlines logo]()
$663
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/284:15 pm
GNV
- SAN
1 stop7h 22m
American Airlines
Wed 4/110:00 pm
SAN
- GNV
1 stop9h 59m
American Airlines
Deal found 3/13![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
GNV
- SAN
1 stop9h 10m
American Airlines
Sun 4/56:15 am
SAN
- GNV
1 stop6h 30m
American Airlines
Deal found 3/12![American Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
GNV
- SAN
1 stop9h 10m
American Airlines
Sat 4/117:15 am
SAN
- GNV
1 stop6h 29m
American Airlines
Deal found 3/15![American Airlines logo]()
$604
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:03 pm
GNV
- SAN
1 stop7h 22m
Delta
Tue 4/2110:30 pm
SAN
- GNV
1 stop7h 54m
Delta
Deal found 3/15![Delta logo]()
$492
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
GNV
- SAN
1 stop8h 53m
American Airlines
Tue 4/2112:17 pm
SAN
- GNV
1 stop7h 32m
American Airlines
Deal found 3/12![American Airlines logo]()
$677
One-way flights from Gainesville to San DiegoSearch for one-way flight options from Gainesville to San Diego. Find affordable one-way fares based on user searches. Data last updated March 16, 2026.
Search for one-way flight options from Gainesville to San Diego. Find affordable one-way fares based on user searches. Data last updated March 16, 2026.
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
GNV
- SAN
1 stop8h 53m
American Airlines
Deal found 3/12![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:07 pm
GNV
- SAN
1 stop8h 43m
American Airlines
Deal found 3/15![American Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:24 am
GNV
- SAN
1 stop10h 04m
American Airlines
Deal found 3/16![American Airlines logo]()
$451
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:32 pm
GNV
- SAN
1 stop9h 15m
Delta
Deal found 3/16![Delta logo]()
$491
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:45 pm
GNV
- SAN
1 stop8h 14m
American Airlines
Deal found 3/16![American Airlines logo]()
$505
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 am
GNV
- SAN
1 stop6h 52m
Delta
Deal found 3/16![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:40 pm
GNV
- SAN
2 stops10h 35m
Delta
Deal found 3/11![Delta logo]()
$898
Find flight deals from Gainesville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $492 (Delta) |
One-way from | $339 (American Airlines) |
Popular in | April |
Cheapest in | July |
Average price | $518 |
Cheapflights Fare Finder
Customize your flight search to find flights from Gainesville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Gainesville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Fri 4/17
7:03 pm-11:25 pm
1 stop7h 22m
San Diego
Tue 4/21
10:30 pm-9:24 am
1 stop7h 54m
$492
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Mon 4/6
6:00 am-12:10 pm
1 stop9h 10m
San Diego
Sat 4/11
7:15 am-4:44 pm
1 stop6h 29m
$604
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Sun 4/19
6:00 am-11:53 am
1 stop8h 53m
San Diego
Tue 4/21
9:12 am-9:44 pm
2 stops9h 32m
$682
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Mon 3/30
7:17 am-12:46 pm
1 stop8h 29m
San Diego
Fri 4/3
10:49 am-11:00 pm
1 stop9h 11m
$741
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Sat 3/28
7:17 am-4:00 pm
2 stops11h 43m
San Diego
Wed 4/1
6:24 am-7:20 pm
2 stops9h 56m
$755
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Thu 3/26
6:00 am-9:52 am
1 stop6h 52m
San Diego
Sun 3/29
9:55 pm-9:29 am
1 stop8h 34m
$773
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Fri 3/20
4:15 pm-10:23 pm
1 stop9h 08m
San Diego
Sat 3/21
6:24 am-6:54 pm
2 stops9h 30m
$870
Cheapest one-way
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Tue 5/12
10:11 am-4:30 pm
1 stop9h 19m
$339
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Wed 4/15
6:00 am-11:53 am
1 stop8h 53m
$339
GainesvilleSan Diego
GNV - SAN
GNVSAN
Gainesville Regional
Fri 4/10
3:07 pm-8:50 pm
1 stop8h 43m
$350
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Gainesville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to San Diego in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Gainesville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Gainesville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Gainesville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Gainesville with our price prediction graph.
GNV-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Gainesville to San Diego
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 16, 2026.
Read through reviews of airlines operating flights from Gainesville to San Diego, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Gainesville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
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Gainesville and San Diego flights
Browse other Gainesville and San Diego flight options. Last updated on March 16, 2026.
Other flights from Gainesville
Browse through other flights departing from Gainesville. Flights are based on user searches made on Cheapflights and were last updated on March 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 16, 2026.
Top 2 airlines flying from Gainesville to San Diego
Discover the top 2 airlines that operate flights from Gainesville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$388 | Average$474 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$389 | Average$566 | FlexibilityNo cancel fee | On-timeN/A |