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$77+ Cheap flights from O'Hare Intl (ORD) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — SAN
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago O'Hare Intl to San Diego are usually found in October or September, booked 71 days in advance, depart on a Friday or Thursday and return on a Thursday

Cheap flight deals from O'Hare Intl to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$160
(Kiwi.com)

One-way from

$77
(United Airlines)

Popular in

March

Cheapest in

October

Average price

$267

Good round-trip deal

$190 or less

Good one-way deal

$97 or less
Provider with most accurate pricing for Chicago O'Hare Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Chicago O'Hare Intl-San Diego flights.
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From Chicago O'Hare Intl to San Diego
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One-way flight from Chicago O'Hare Intl to San Diego
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Highest demand for flights based on searches. 25% potential increase in price ($110 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Chicago O'Hare Intl to San Diego.
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Price to beat on a one-way flight from Chicago O'Hare Intl to San Diego.
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Find flight deals from O'Hare Intl to San Diego

Cheapest flights from O'Hare Intl to San Diego
Explore the most affordable flight options available from O'Hare Intl to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:26 pmORD - SAN
2 stops34h 20mFrontier
Mon 12/156:34 amSAN - ORD
1 stop15h 38mFrontier
Deal found 11/10$160
This Trip.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:00 amORD - SAN
1 stop18h 59mFrontier
Sun 12/216:25 amSAN - ORD
1 stop15h 47mFrontier
Deal found 11/11$161
This Cheapflightsfares deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:05 pmORD - SAN
Nonstop4h 28mAlaska Airlines
Sat 12/138:00 amSAN - ORD
Nonstop4h 09mAlaska Airlines
Deal found 11/11$163
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:20 amORD - SAN
2 stops17h 26mMultiple Airlines
Thu 12/113:47 pmSAN - ORD
1 stop17h 55mMultiple Airlines
Deal found 11/11$164
This Alaska Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:55 amORD - SAN
Nonstop4h 27mAlaska Airlines
Tue 12/161:45 pmSAN - ORD
Nonstop4h 09mAlaska Airlines
Deal found 11/11$165
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:53 pmORD - SAN
1 stop18h 17mFrontier
Thu 12/116:34 amSAN - ORD
1 stop15h 38mFrontier
Deal found 11/11$166
This Alaska Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:55 amORD - SAN
Nonstop4h 27mAlaska Airlines
Tue 12/95:53 pmSAN - ORD
Nonstop3h 57mAlaska Airlines
Deal found 11/12$167
This Expedia deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:24 pmORD - SAN
1 stop10h 35mMultiple Airlines
Sun 12/78:00 amSAN - ORD
Nonstop4h 09mMultiple Airlines
Deal found 11/11$168
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:10 amORD - SAN
Nonstop4h 30mUnited Airlines
Tue 12/161:05 pmSAN - ORD
1 stop8h 05mUnited Airlines
Deal found 11/11$169
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:15 amORD - SAN
Nonstop4h 33mAmerican Airlines
Sun 1/116:20 amSAN - ORD
Nonstop4h 09mAmerican Airlines
Deal found 11/12$170
This Expedia deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:05 pmORD - SAN
Nonstop4h 28mMultiple Airlines
Thu 12/186:25 amSAN - ORD
1 stop10h 27mMultiple Airlines
Deal found 11/12$171
This Expedia deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:24 pmORD - SAN
1 stop10h 35mMultiple Airlines
Mon 12/158:00 amSAN - ORD
Nonstop4h 09mMultiple Airlines
Deal found 11/12$172

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to San Diego that are best for you.

Fly from

O'Hare Intl

Fly to

San Diego

Route

Depart

Return

Price

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 1/29

9:05 am-11:48 am

Nonstop4h 43m

San Diego

Sat 2/7

10:52 am-5:05 pm

Nonstop4h 13m

$167

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 1/21

9:05 am-11:48 am

Nonstop4h 43m

San Diego

Sun 1/25

2:11 pm-8:25 pm

Nonstop4h 14m

$167

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 1/7

2:40 pm-8:49 pm

1 stop8h 09m

San Diego

Fri 1/16

2:11 pm-8:25 pm

Nonstop4h 14m

$173

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Sat 12/20

8:58 pm-11:44 pm

Nonstop4h 46m

San Diego

Thu 12/25

1:30 pm-8:02 pm

Nonstop4h 32m

$175

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 12/4

7:10 am-9:40 am

Nonstop4h 30m

San Diego

Sun 12/7

5:08 pm-11:15 pm

Nonstop4h 07m

$177

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Fri 12/12

4:25 pm-10:10 pm

1 stop7h 45m

San Diego

Tue 12/16

2:50 pm-10:35 pm

1 stop5h 45m

$184

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Sat 1/17

3:44 pm-6:26 pm

Nonstop4h 42m

San Diego

Wed 1/21

6:03 pm-1:10 pm

1 stop17h 07m

$195

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 2/11

8:00 am-5:20 pm

1 stop11h 20m

San Diego

Wed 2/18

8:35 am-2:58 pm

Nonstop4h 23m

$195

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 1/7

9:00 am-11:43 am

Nonstop4h 43m

San Diego

Tue 1/13

9:37 am-11:50 pm

1 stop12h 13m

$197

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Sat 12/6

6:37 pm-12:15 am

1 stop7h 38m

San Diego

Wed 12/10

5:08 pm-11:15 pm

Nonstop4h 07m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/13

Showing 1-10 of 22 results
1
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Compare providers for flights from O'Hare Intl to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to San Diego in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
JustAirTicketPrice Accuracy-Trust Score*1 star
PricelinePrice Accuracy1 starTrust Score*3 stars
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star
CheapOairPrice Accuracy3 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-San Diego flights, users find the pricing of CheapOair to be most consistent on Cheapflights vs. CheapOair Users can find the same prices on Chicago O'Hare Intl Airport-San Diego flight deals on Cheapflights vs. CheapOair >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-San Diego flights, Cheapflights users trust CheapOair the most. CheapOair has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to San Diego

How far ahead should I book a flight from Chicago O'Hare Intl Airport to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to San Diego. Price data was last updated on November 7, 2025.

The price you pay for your flight from Chicago O'Hare Intl Airport to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to San Diego?

Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to San Diego (average of $88). Flying from Chicago O'Hare Intl Airport to San Diego in May is currently the most expensive (average of $198). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to SAN?

Find hourly flight availability from O'Hare Intl to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

It’s optimal to fly from Chicago O'Hare Intl Airport to San Diego at noon. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the afternoon.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to San Diego?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to San Diego. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to San Diego flight should consider departing on Saturday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for Chicago O'Hare Intl Airport to San Diego flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Chicago O'Hare Intl Airport to San Diego trip
Airports
ORD

For a quick departure, take the "L" train to ORD, avoiding Chicago traffic delays common with taxis or rideshares.

Read more about ORDby Ramsey Qubein
SAN

Upon arrival at SAN, use the free San Diego Flyer shuttle to connect to the Old Town Transit Center for easy downtown access.

Read more about SANby Blane Bachelor
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on ORD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Blane Bachelor

Blane Bachelor

Expert on SAN

Blane Bachelor

Blane Bachelor

Blane Bachelor is a journalist and editor specializing in travel and aviation who writes regularly for top global outlets. Born and raised in Florida, Blane has worked and lived in four countries, including the Netherlands, where she’s currently based with her family. Her favorite way to get to know a new destination is by running or riding a bike around town – or hearing a spooky ghost story about local history. She will always choose the window seat.

Read more

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated November 13, 2025.
See what other customers who have flown with Alaska Airlines, United Airlines, and American Airlines from Chicago O'Hare Intl Airport to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,282 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,282 reviews
Alaska Airlines
8.0
Very good
11,282 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
9,016 reviews
Alaska Airlines
8.0
Very good
11,282 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,050 reviews
Alaska Airlines
8.0
Very good
11,282 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Spirit Airlines
6.3
Okay
8,139 reviews
Alaska Airlines
8.0
Very good
11,282 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,112 reviews
Alaska Airlines
8.0
Very good
11,282 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Chicago O'Hare Intl?

    San Diego (SAN) is the airport you will fly into if you book a flight from Chicago O'Hare Intl to San Diego. You should not have trouble finding flights to San Diego from Chicago O'Hare Intl; the airport handles an average of 30 inbound flights from Chicago O'Hare Intl per day. You should also have plenty of airline options to choose from since 8 airlines have flights to the San Diego airport from Chicago O'Hare Intl. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How long is the flight from Chicago O'Hare Intl Airport to San Diego?

    Departing from Chicago O'Hare Intl Airport to San Diego will take you 4h 43m. There are 1719 mi between Chicago O'Hare Intl Airport and San Diego. All flights are typically nonstop.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to San Diego round-trip?

    According to our current data, Spirit Airlines ($87), Frontier ($104), and Alaska Airlines ($142) offers the cheapest pricing from Chicago O'Hare Intl Airport to San Diego. These flights start at 73% lower than the current average price 3 months from now.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to San Diego?

    The top 3 most reliable airlines when flying from Chicago O'Hare Intl Airport to San Diego are Frontier (100%), Japan Airlines (83%) and American Airlines (79%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to San Diego?

    Looking at all options, your cheapest flight can be booked for $76. While the most popular route (Chicago O'Hare Intl - San Diego) can be booked for $134 on average, our data indicates $657 when flying from Chicago O'Hare Intl Airport to San Diego.

  • Can I find deals for flights from O'Hare Intl to San Diego that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to San Diego.

  • Can I find deals for business class flights from O'Hare Intl to San Diego?

    Yes. Cheapflights offers flight deals from O'Hare Intl to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to San Diego?

    Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to San Diego (average of $88). Flying from Chicago O'Hare Intl Airport to San Diego in May is currently the most expensive (average of $198). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Alternative routes for O'Hare Intl to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from O'Hare Intl to San Diego

Discover the top 8 airlines that operate flights from O'Hare Intl to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$87Average$201FlexibilityNo cancel feeOn-time65%
FrontierCheapest$104Average$204FlexibilityNo cancel feeOn-time62%
Alaska AirlinesCheapest$142Average$230FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$165Average$370FlexibilityNo cancel feeOn-time71%
Hawaiian AirlinesCheapest$168Average$237FlexibilityNo cancel feeOn-time85%
United AirlinesCheapest$172Average$426FlexibilityNo cancel feeOn-time69%
DeltaCheapest$223Average$330FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$296Average$501FlexibilityNo cancel feeOn-time63%

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