Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Napa Valley to San Diego as you normally would.
Flights from Napa Valley to San Diego lean towards being more expensive in November. Prices are generally better when you fly from Napa Valley to San Diego in August, with the cheapest ticket starting at $96.
To save up to 86% on this flight, we recommend booking at least 30 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Napa Valley to San Diego from $205 1-2 weeks out and tickets from $303 for flights departing within the next 72 hours.