$146+ Cheap flights from Knoxville to San Antonio (TYS - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
Jul 16 — Jul 231
Round-trip
1 adult, Economy
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Best
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Cheapest flights from Knoxville to San AntonioExplore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:45 pm
TYS
- SAT
1 stop6h 45m
Southwest
Tue 11/108:25 am
SAT
- TYS
1 stop4h 35m
Southwest
Deal found 6/11![Southwest logo]()
$230
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:57 pm
TYS
- SAT
1 stop7h 31m
Delta
Tue 12/82:10 pm
SAT
- TYS
1 stop6h 35m
Delta
Deal found 6/11![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:55 pm
TYS
- SAT
1 stop6h 00m
Southwest
Tue 7/147:15 am
SAT
- TYS
1 stop5h 50m
Southwest
Deal found 6/12![Southwest logo]()
$295
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:45 pm
TYS
- SAT
2 stops11h 15m
Southwest
Wed 7/2912:00 pm
SAT
- TYS
2 stops8h 20m
Southwest
Deal found 6/11![Southwest logo]()
$305
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:08 pm
TYS
- SAT
1 stop5h 52m
American Airlines
Fri 11/276:00 am
SAT
- TYS
1 stop4h 23m
American Airlines
Deal found 6/11![American Airlines logo]()
$306
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:00 pm
TYS
- SAT
1 stop4h 28m
Delta
Sun 10/255:30 am
SAT
- TYS
1 stop4h 36m
Delta
Deal found 6/11![Delta logo]()
$310
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:52 pm
TYS
- SAT
1 stop7h 32m
American Airlines
Wed 9/169:37 am
SAT
- TYS
1 stop6h 05m
American Airlines
Deal found 6/16![American Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:00 am
TYS
- SAT
2 stops6h 20m
Southwest
Tue 8/117:35 am
SAT
- TYS
2 stops5h 45m
Southwest
Deal found 6/15![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
TYS
- SAT
1 stop7h 29m
United Airlines
Sat 8/85:57 pm
SAT
- TYS
1 stop4h 15m
United Airlines
Deal found 6/11![United Airlines logo]()
$322
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:32 pm
TYS
- SAT
1 stop23h 24m
Frontier
Sun 6/287:51 pm
SAT
- TYS
1 stop22h 46m
Frontier
Deal found 6/11![Frontier logo]()
$323
Best flights from Knoxville to San AntonioDiscover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
Discover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:45 pm
TYS
- SAT
2 stops11h 15m
Southwest
Tue 8/47:35 am
SAT
- TYS
2 stops5h 45m
Southwest
Deal found 6/15![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:54 pm
TYS
- SAT
1 stop5h 47m
Delta
Mon 7/136:16 pm
SAT
- TYS
1 stop4h 36m
Delta
Deal found 6/12![Delta logo]()
$378
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
TYS
- SAT
2 stops11h 43m
United Airlines
Wed 8/194:12 pm
SAT
- TYS
1 stop4h 33m
United Airlines
Deal found 6/15![United Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:31 pm
TYS
- SAT
1 stop5h 29m
American Airlines
Sun 7/56:01 am
SAT
- TYS
1 stop5h 55m
American Airlines
Deal found 6/14![American Airlines logo]()
$447
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:45 pm
TYS
- SAT
2 stops11h 15m
Southwest
Thu 7/165:00 am
SAT
- TYS
1 stop7h 45m
Southwest
Deal found 6/11![Southwest logo]()
$338
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:21 pm
TYS
- SAT
1 stop6h 37m
United Airlines
Wed 9/1612:00 pm
SAT
- TYS
2 stops9h 49m
United Airlines
Deal found 6/15![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:40 am
TYS
- SAT
2 stops7h 45m
Southwest
Mon 7/139:45 am
SAT
- TYS
2 stops8h 25m
Southwest
Deal found 6/15![Southwest logo]()
$427
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:02 pm
TYS
- SAT
1 stop5h 49m
United Airlines
Fri 8/212:15 pm
SAT
- TYS
1 stop6h 30m
United Airlines
Deal found 6/13![United Airlines logo]()
$429
Last-minute flights from Knoxville to San AntonioDiscover last-minute flight deals from Knoxville to San Antonio. Data last updated June 16, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Antonio. Data last updated June 16, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:32 pm
TYS
- SAT
1 stop23h 24m
Frontier
Sun 6/287:51 pm
SAT
- TYS
1 stop22h 46m
Frontier
Deal found 6/11![Frontier logo]()
$323
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:55 pm
TYS
- SAT
1 stop6h 00m
Southwest
Tue 7/147:15 am
SAT
- TYS
1 stop5h 50m
Southwest
Deal found 6/12![Southwest logo]()
$295
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:07 pm
TYS
- SAT
1 stop5h 33m
American Airlines
Tue 7/145:01 am
SAT
- TYS
1 stop5h 12m
American Airlines
Deal found 6/14![American Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:31 pm
TYS
- SAT
1 stop6h 33m
American Airlines
Thu 7/165:47 pm
SAT
- TYS
1 stop5h 04m
American Airlines
Deal found 6/11![American Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:45 pm
TYS
- SAT
2 stops11h 15m
Southwest
Tue 8/47:35 am
SAT
- TYS
2 stops5h 45m
Southwest
Deal found 6/15![Southwest logo]()
$337
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:00 am
TYS
- SAT
1 stop5h 02m
American Airlines
Mon 7/205:47 pm
SAT
- TYS
1 stop5h 04m
American Airlines
Deal found 6/15![American Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:55 pm
TYS
- SAT
1 stop6h 00m
Southwest
Mon 7/209:45 am
SAT
- TYS
2 stops8h 25m
Southwest
Deal found 6/15![Southwest logo]()
$351
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:45 pm
TYS
- SAT
2 stops11h 15m
Southwest
Wed 7/2912:00 pm
SAT
- TYS
2 stops8h 20m
Southwest
Deal found 6/11![Southwest logo]()
$305
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:40 am
TYS
- SAT
1 stop4h 40m
Southwest
Mon 7/2712:25 pm
SAT
- TYS
1 stop5h 45m
Southwest
Deal found 6/16![Southwest logo]()
$369
One-way flights from Knoxville to San AntonioSearch for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
Search for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:19 pm
TYS
- SAT
1 stop23h 25m
Frontier
Deal found 6/12![Frontier logo]()
$146
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:55 pm
TYS
- SAT
1 stop6h 00m
Southwest
Deal found 6/13![Southwest logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:20 pm
TYS
- SAT
2 stops26h 17m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:20 pm
TYS
- SAT
2 stops26h 17m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$174
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:40 am
TYS
- SAT
1 stop4h 40m
Southwest
Deal found 6/13![Southwest logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:30 am
TYS
- SAT
2 stops37h 14m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:42 pm
TYS
- SAT
2 stops41h 08m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$190
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:40 am
TYS
- SAT
1 stop5h 03m
Delta
Deal found 6/13![Delta logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:29 pm
TYS
- SAT
2 stops23h 29m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$194
Find flight deals from Knoxville to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $230 (Southwest) |
One-way from | $146 (Booking.com) |
Popular in | June |
Cheapest in | January |
Average price | $531 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Tue 7/14
12:45 pm-11:00 pm
2 stops11h 15m
San Antonio
Tue 8/4
7:35 am-2:20 pm
2 stops5h 45m
$337
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Tue 7/14
12:45 pm-11:00 pm
2 stops11h 15m
San Antonio
Thu 7/16
5:00 am-1:45 pm
1 stop7h 45m
$338
Quickest round-trip
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Fri 7/3
3:54 pm-8:41 pm
1 stop5h 47m
San Antonio
Mon 7/13
6:16 pm-11:52 pm
1 stop4h 36m
$378
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Tue 8/18
7:00 am-5:43 pm
2 stops11h 43m
San Antonio
Wed 8/19
4:12 pm-9:45 pm
1 stop4h 33m
$380
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sat 9/5
2:21 pm-7:58 pm
1 stop6h 37m
San Antonio
Wed 9/16
12:00 pm-10:49 pm
2 stops9h 49m
$397
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Thu 7/9
6:40 am-1:25 pm
2 stops7h 45m
San Antonio
Mon 7/13
9:45 am-7:10 pm
2 stops8h 25m
$427
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Mon 8/17
6:02 pm-10:51 pm
1 stop5h 49m
San Antonio
Fri 8/21
2:15 pm-9:45 pm
1 stop6h 30m
$429
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Thu 7/2
5:31 pm-10:00 pm
1 stop5h 29m
San Antonio
Sun 7/5
6:01 am-12:56 pm
1 stop5h 55m
$447
Cheapest one-way
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Mon 8/3
7:20 pm-8:37 pm
2 stops26h 17m
$169
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Fri 8/7
5:45 pm-10:57 pm
1 stop6h 12m
$185
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
TYS-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Antonio
What is the cheapest month to book a flight from Knoxville to San Antonio?
Currently, January is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $290). Flying from Knoxville to San Antonio in June is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated June 16, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Knoxville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Knoxville and San Antonio flights
Browse other Knoxville and San Antonio flight options. Last updated on June 16, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on June 16, 2026.
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Top 4 airlines flying from Knoxville to San Antonio
Discover the top 4 airlines that operate flights from Knoxville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$488 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$236 | Average$330 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$251 | Average$339 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$264 | Average$393 | FlexibilityNo cancel fee | On-timeN/A |