$132+ Cheap flights from Knoxville to San Antonio (TYS - SAT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to San Antonio
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Best
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Cheapest flights from Knoxville to San AntonioExplore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:30 am -
1 stop13h 55m
Sat 11/78:20 pm -
1 stop15h 59m
Deal found 9/12![Multiple Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:25 pm -
1 stop6h 30m
Tue 11/106:45 am -
1 stop6h 20m
Deal found 9/13![Southwest logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:30 am -
1 stop13h 55m
Fri 11/612:38 pm -
1 stop8h 30m
Deal found 9/12![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:52 pm -
1 stop19h 16m
Fri 10/2310:03 am -
1 stop10h 38m
Deal found 9/11![Multiple Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:23 pm -
1 stop4h 25m
Mon 10/196:20 pm -
1 stop4h 38m
Deal found 9/14![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:25 pm -
1 stop6h 35m
Mon 11/166:00 am -
1 stop8h 30m
Deal found 9/13![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:23 pm -
1 stop7h 10m
Wed 10/285:30 am -
1 stop7h 10m
Deal found 9/10![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:37 pm -
1 stop19h 21m
Thu 11/129:25 am -
2 stops36h 11m
Deal found 9/10![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:45 am -
2 stops36h 41m
Sat 10/318:20 pm -
1 stop16h 51m
Deal found 9/11![Multiple Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:23 pm -
1 stop7h 10m
Mon 10/266:20 pm -
1 stop4h 39m
Deal found 9/14![Delta logo]()
$315
Best flights from Knoxville to San AntonioDiscover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:15 pm -
1 stop6h 30m
Mon 12/76:45 am -
1 stop6h 20m
Deal found 9/14![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am -
1 stop5h 03m
Mon 10/196:20 pm -
1 stop4h 38m
Deal found 9/10![Delta logo]()
$316
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:00 am -
1 stop4h 46m
Mon 11/22:20 pm -
1 stop6h 37m
Deal found 9/12![United Airlines logo]()
$477
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:25 pm -
1 stop6h 20m
Sun 11/15:55 am -
2 stops8h 05m
Deal found 9/10![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop7h 10m
Sun 10/255:30 am -
1 stop4h 24m
Deal found 9/13![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:15 pm -
2 stops5h 40m
Tue 10/2711:55 am -
2 stops8h 10m
Deal found 9/11![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:25 am -
2 stops10h 23m
Tue 12/89:41 am -
2 stops10h 06m
Deal found 9/13![United Airlines logo]()
$487
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
1 stop6h 20m
Sun 10/255:25 pm -
1 stop4h 20m
Deal found 9/11![Southwest logo]()
$403
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:40 am -
1 stop5h 02m
Thu 11/56:50 am -
1 stop5h 41m
Deal found 9/13![Delta logo]()
$493
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:20 pm -
2 stops7h 35m
Mon 10/263:20 pm -
2 stops6h 25m
Deal found 9/14![Southwest logo]()
$427
Last-minute flights from Knoxville to San AntonioDiscover last-minute flight deals from Knoxville to San Antonio. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Antonio. Data last updated September 15, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 11m
Mon 10/511:47 am -
1 stop5h 18m
Deal found 9/10![United Airlines logo]()
$316
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:23 pm -
1 stop4h 25m
Mon 10/196:20 pm -
1 stop4h 38m
Deal found 9/14![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:25 pm -
1 stop6h 20m
Tue 10/206:00 am -
1 stop9h 40m
Deal found 9/14![Southwest logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:52 pm -
1 stop19h 16m
Fri 10/2310:03 am -
1 stop10h 38m
Deal found 9/11![Multiple Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:23 pm -
1 stop7h 10m
Wed 10/285:30 am -
1 stop7h 10m
Deal found 9/10![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:52 pm -
1 stop19h 16m
Wed 10/2810:29 pm -
2 stops46h 12m
Deal found 9/10![Multiple Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:23 pm -
1 stop7h 10m
Mon 10/266:20 pm -
1 stop4h 39m
Deal found 9/14![Delta logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:45 am -
2 stops36h 41m
Sat 10/318:20 pm -
1 stop16h 51m
Deal found 9/11![Multiple Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:25 pm -
1 stop6h 20m
Sun 11/112:00 pm -
1 stop5h 45m
Deal found 9/10![Southwest logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:18 pm -
2 stops43h 40m
Sat 11/78:20 pm -
1 stop15h 59m
Deal found 9/12![Multiple Airlines logo]()
$325
One-way flights from Knoxville to San AntonioSearch for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:23 pm -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$132
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:23 pm -
1 stop4h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$150
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:25 pm -
1 stop6h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Southwest logo]()
$152
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$205
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
2 stops10h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:08 pm -
3 stops53h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:33 pm -
3 stops36h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop5h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![American Airlines logo]()
$254
Find flight deals from Knoxville to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $263 (Kiwi.com) |
One-way from | $132 (Delta) |
Popular in | September |
Cheapest in | January |
Average price | $704 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Wed 10/21
6:23 pm-12:33 am
1 stop7h 10m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$132
Quickest round-trip
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Mon 10/12
6:23 pm-9:48 pm
1 stop4h 25m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$150
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Fri 10/2
6:00 am-12:11 pm
1 stop7h 11m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$205
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Wed 10/21
6:00 am-3:53 pm
2 stops10h 53m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$207
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Thu 10/8
3:08 pm-7:26 pm
3 stops53h 18m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$211
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Thu 10/8
7:15 am-3:15 pm
2 stops9h 00m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$235
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Sun 9/27
5:38 pm-11:58 am
1 stop19h 20m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$267
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Tue 9/29
12:05 pm-3:53 pm
1 stop4h 48m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Thu 12/3
4:15 pm-9:45 pm
1 stop6h 30m
San Antonio
Mon 12/7
6:45 am-2:05 pm
1 stop6h 20m
$300
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Fri 10/16
5:40 am-9:43 am
1 stop5h 03m
San Antonio
Mon 10/19
6:20 pm-11:58 pm
1 stop4h 38m
$316
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
TYS-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Antonio
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated September 15, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Knoxville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Knoxville and San Antonio flights
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Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Top 4 airlines flying from Knoxville to San Antonio
Discover the top 4 airlines that operate flights from Knoxville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$318 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$264 | Average$448 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$358 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$488 | FlexibilityNo cancel fee | On-time63% |