$158+ Cheap flights from Knoxville to San Antonio (TYS - SAT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
Nov 17 — Nov 241
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to San Antonio
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Cheapest flights from Knoxville to San AntonioExplore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 18, 2026.
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 18, 2026.
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
1 stop4h 46m
Tue 11/179:35 am -
1 stop7h 19m
Deal found 10/13![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:15 pm -
1 stop6h 30m
Tue 11/1712:00 pm -
2 stops7h 50m
Deal found 10/13![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:55 am -
1 stop4h 56m
Thu 12/2411:50 am -
1 stop5h 59m
Deal found 10/14![United Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:10 pm -
1 stop4h 56m
Sun 11/155:25 am -
1 stop5h 03m
Deal found 10/13![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:05 am -
2 stops6h 10m
Wed 11/1812:00 pm -
2 stops7h 50m
Deal found 10/14![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
1 stop6h 39m
Mon 11/234:32 pm -
1 stop4h 50m
Deal found 10/16![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:36 pm -
1 stop6h 23m
Tue 12/1510:54 am -
1 stop5h 36m
Deal found 10/15![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:25 pm -
1 stop6h 35m
Sun 11/155:25 am -
2 stops5h 45m
Deal found 10/14![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:25 pm -
1 stop6h 30m
Tue 12/1512:00 pm -
2 stops7h 45m
Deal found 10/15![Southwest logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:32 pm -
1 stop7h 21m
Sun 11/156:07 am -
1 stop6h 10m
Deal found 10/16![American Airlines logo]()
$384
Best flights from Knoxville to San AntonioDiscover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 18, 2026.
Discover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 18, 2026.
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
1 stop4h 46m
Tue 11/179:35 am -
1 stop7h 19m
Deal found 10/13![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:15 pm -
1 stop6h 30m
Tue 11/1712:00 pm -
2 stops7h 50m
Deal found 10/13![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:10 pm -
1 stop4h 56m
Sun 11/155:25 am -
1 stop5h 03m
Deal found 10/13![Delta logo]()
$348
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:36 pm -
1 stop6h 23m
Tue 12/1510:54 am -
1 stop5h 36m
Deal found 10/15![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:40 pm -
2 stops8h 45m
Tue 12/156:45 am -
2 stops8h 55m
Deal found 10/15![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:15 pm -
1 stop7h 10m
Fri 11/277:20 am -
1 stop6h 40m
Deal found 10/17![Southwest logo]()
$459
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:45 am -
2 stops14h 52m
Fri 11/272:20 pm -
1 stop6h 37m
Deal found 10/14![United Airlines logo]()
$546
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:15 am -
2 stops6h 10m
Fri 10/304:40 pm -
1 stop5h 05m
Deal found 10/13![Southwest logo]()
$482
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:45 am -
2 stops9h 53m
Sun 11/155:30 am -
2 stops10h 29m
Deal found 10/16![United Airlines logo]()
$568
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:40 pm -
1 stop6h 55m
Mon 11/29:35 am -
2 stops10h 19m
Deal found 10/13![United Airlines logo]()
$612
Last-minute flights from Knoxville to San AntonioDiscover last-minute flight deals from Knoxville to San Antonio. Data last updated October 18, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Antonio. Data last updated October 18, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:51 am -
2 stops8h 12m
Sun 11/85:30 am -
1 stop4h 42m
Deal found 10/16![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:32 pm -
1 stop7h 32m
Wed 11/186:00 am -
1 stop7h 05m
Deal found 10/14![American Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:15 pm -
1 stop6h 55m
Wed 11/1812:00 pm -
2 stops7h 50m
Deal found 10/14![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:10 pm -
1 stop4h 56m
Sun 11/155:25 am -
1 stop5h 03m
Deal found 10/13![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:25 pm -
1 stop6h 35m
Sun 11/155:25 am -
2 stops5h 45m
Deal found 10/14![Southwest logo]()
$373
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:32 pm -
1 stop7h 21m
Sun 11/156:07 am -
1 stop6h 10m
Deal found 10/16![American Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:30 am -
1 stop13h 55m
Sun 11/159:25 am -
2 stops27h 06m
Deal found 10/13![Multiple Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
1 stop6h 39m
Mon 11/234:32 pm -
1 stop4h 50m
Deal found 10/16![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:30 am -
1 stop5h 18m
Fri 11/276:07 am -
1 stop6h 19m
Deal found 10/14![American Airlines logo]()
$408
One-way flights from Knoxville to San AntonioSearch for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated October 18, 2026.
Search for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated October 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:30 am -
1 stop13h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$158
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
1 stop7h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![United Airlines logo]()
$159
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:50 pm -
2 stops7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Southwest logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:30 am -
2 stops35h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:17 pm -
2 stops44h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$183
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:25 pm -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Southwest logo]()
$185
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/154:10 pm -
2 stops6h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Southwest logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:10 am -
2 stops35h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:03 pm -
2 stops22h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:37 pm -
1 stop19h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:30 am -
3 stops38h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$221
Find flight deals from Knoxville to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (American Airlines) |
One-way from | $158 (Kiwi.com) |
Popular in | September |
Cheapest in | January |
Average price | $376 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 18, 2026.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Wed 11/11
2:40 pm-7:48 pm
1 stop6h 08m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$159
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Sat 11/7
2:50 pm-9:15 pm
2 stops7h 25m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$164
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Wed 11/11
1:56 pm-10:51 pm
2 stops9h 55m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$164
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Fri 1/15
6:00 am-9:54 am
1 stop4h 54m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$185
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Thu 11/12
6:33 pm-7:25 pm
3 stops49h 52m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$204
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Fri 1/15
4:10 pm-10:00 pm
2 stops6h 50m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$205
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Tue 11/17
5:40 am-9:59 am
1 stop5h 19m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$214
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Fri 1/15
5:59 pm-9:10 am
3 stops40h 11m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Fri 10/23
8:00 am-7:26 pm
2 stops36h 26m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$287
Quickest round-trip
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Wed 10/21
12:06 pm-3:24 pm
1 stop4h 18m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$315
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
TYS-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Antonio
What is the cheapest month to book a flight from Knoxville to San Antonio?
Currently, January is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $290). Flying from Knoxville to San Antonio in September is currently the most expensive (average of $704). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to San Antonio?
Airfare is below average for this route at the moment.
Knoxville to San Antonio flights typically cost between $361 and $461 in November.The cheapest round-trip price found within the last 5 days was $317 on American Airlines (Nov 11-Nov 18).
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated October 18, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
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Find useful and relevant information for your journey from Knoxville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Knoxville and San Antonio flights
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Top 4 airlines flying from Knoxville to San Antonio
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$318 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$372 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$430 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$299 | Average$476 | FlexibilityNo cancel fee | On-time63% |