$147+ Cheap flights from Knoxville to San Antonio (TYS - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
Sep 17 — Sep 241
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to San Antonio
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Best
Last-minute
One-way
Cheapest flights from Knoxville to San AntonioExplore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2026.
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2026.
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:25 pm -
1 stop6h 15m
Sat 10/246:00 am -
1 stop7h 15m
Deal found 8/13![Southwest logo]()
$256
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:07 pm -
1 stop5h 46m
Mon 11/167:27 am -
1 stop6h 56m
Deal found 8/13![American Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:50 pm -
1 stop5h 04m
Wed 9/165:00 am -
1 stop5h 17m
Deal found 8/14![American Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:30 pm -
1 stop6h 40m
Tue 9/299:20 am -
2 stops9h 35m
Deal found 8/16![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
1 stop5h 03m
Sun 10/255:30 am -
1 stop4h 24m
Deal found 8/13![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:40 am -
1 stop5h 03m
Tue 10/204:29 pm -
1 stop4h 53m
Deal found 8/14![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am -
2 stops8h 29m
Mon 9/214:12 pm -
1 stop4h 33m
Deal found 8/14![United Airlines logo]()
$330
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:40 pm -
2 stops8h 45m
Mon 11/166:00 am -
1 stop8h 30m
Deal found 8/13![Southwest logo]()
$335
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:38 pm -
1 stop6h 10m
Fri 10/236:20 pm -
1 stop4h 39m
Deal found 8/14![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:10 am -
2 stops8h 05m
Tue 9/227:35 am -
2 stops5h 45m
Deal found 8/14![Southwest logo]()
$340
Best flights from Knoxville to San AntonioDiscover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2026.
Discover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2026.
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:25 pm -
1 stop6h 15m
Sat 10/246:00 am -
1 stop7h 15m
Deal found 8/13![Southwest logo]()
$256
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:11 pm -
1 stop6h 37m
Sat 10/245:00 pm -
1 stop4h 22m
Deal found 8/18![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:53 pm -
2 stops9h 51m
Fri 9/119:30 am -
2 stops12h 19m
Deal found 8/13![United Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am -
1 stop7h 08m
Tue 9/85:30 am -
1 stop6h 21m
Deal found 8/16![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:30 pm -
1 stop6h 40m
Tue 9/299:20 am -
2 stops9h 35m
Deal found 8/15![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:40 am -
1 stop5h 03m
Tue 10/204:29 pm -
1 stop4h 53m
Deal found 8/14![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:00 am -
1 stop5h 52m
Tue 9/85:30 pm -
1 stop5h 53m
Deal found 8/15![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:50 pm -
1 stop12h 00m
Fri 10/232:35 pm -
2 stops7h 05m
Deal found 8/15![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/95:57 pm -
1 stop7h 31m
Fri 2/124:25 pm -
1 stop6h 21m
Deal found 8/15![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:21 pm -
1 stop6h 37m
Wed 9/1612:00 pm -
2 stops9h 49m
Deal found 8/15![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:20 pm -
1 stop6h 10m
Fri 10/234:40 pm -
1 stop5h 00m
Deal found 8/14![Southwest logo]()
$383
Last-minute flights from Knoxville to San AntonioDiscover last-minute flight deals from Knoxville to San Antonio. Data last updated August 18, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Antonio. Data last updated August 18, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am -
1 stop7h 08m
Tue 9/85:30 am -
1 stop6h 21m
Deal found 8/15![Delta logo]()
$321
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:50 pm -
1 stop5h 04m
Wed 9/165:00 am -
1 stop5h 17m
Deal found 8/14![American Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
1 stop4h 43m
Wed 9/165:30 am -
1 stop4h 48m
Deal found 8/18![Delta logo]()
$347
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop5h 01m
Sun 9/135:00 am -
1 stop6h 53m
Deal found 8/14![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:45 am -
1 stop6h 46m
Fri 9/117:35 am -
1 stop4h 15m
Deal found 8/13![United Airlines logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am -
1 stop13h 25m
Sun 9/139:25 am -
2 stops34h 14m
Deal found 8/14![Multiple Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am -
2 stops8h 29m
Mon 9/214:12 pm -
1 stop4h 33m
Deal found 8/14![United Airlines logo]()
$330
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:10 am -
2 stops8h 05m
Tue 9/227:35 am -
2 stops5h 45m
Deal found 8/14![Southwest logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:38 pm -
1 stop16h 32m
Sun 9/209:25 am -
2 stops34h 14m
Deal found 8/17![Multiple Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:10 am -
1 stop4h 15m
Mon 9/216:00 am -
2 stops6h 25m
Deal found 8/14![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:30 pm -
1 stop6h 40m
Tue 9/299:20 am -
2 stops9h 35m
Deal found 8/16![Southwest logo]()
$308
One-way flights from Knoxville to San AntonioSearch for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated August 18, 2026.
Search for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated August 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:38 pm -
1 stop19h 20m
Deal found 8/13![Multiple Airlines logo]()
$147
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:02 pm -
1 stop5h 49m
Deal found 8/17![United Airlines logo]()
$152
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:45 am -
2 stops9h 53m
Deal found 8/16![United Airlines logo]()
$157
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 11m
Deal found 8/13![United Airlines logo]()
$160
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:23 pm -
1 stop5h 38m
Deal found 8/18![Delta logo]()
$170
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:00 pm -
1 stop10h 05m
Deal found 8/15![Southwest logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:18 pm -
2 stops23h 02m
Deal found 8/17![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:27 pm -
2 stops23h 31m
Deal found 8/17![Multiple Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:39 pm -
2 stops40h 06m
Deal found 8/13![Multiple Airlines logo]()
$190
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:25 pm -
1 stop6h 33m
Deal found 8/17![American Airlines logo]()
$194
Find flight deals from Knoxville to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $285 (Delta) |
One-way from | $147 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $302 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2026.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Mon 10/5
7:25 pm-12:40 am
1 stop6h 15m
San Antonio
Sat 10/24
6:00 am-2:15 pm
1 stop7h 15m
$256
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Tue 10/13
4:11 pm-9:48 pm
1 stop6h 37m
San Antonio
Sat 10/24
5:00 pm-10:22 pm
1 stop4h 22m
$303
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Wed 9/2
7:30 am-1:38 pm
1 stop7h 08m
San Antonio
Tue 9/8
5:30 am-12:51 pm
1 stop6h 21m
$303
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Tue 9/22
5:30 pm-11:10 pm
1 stop6h 40m
San Antonio
Tue 9/29
9:20 am-7:55 pm
2 stops9h 35m
$308
Quickest round-trip
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Tue 10/20
5:40 am-9:43 am
1 stop5h 03m
San Antonio
Tue 10/20
4:29 pm-10:22 pm
1 stop4h 53m
$321
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Tue 2/9
5:57 pm-12:28 am
1 stop7h 31m
San Antonio
Fri 2/12
4:25 pm-11:46 pm
1 stop6h 21m
$345
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Thu 10/15
12:50 pm-11:50 pm
1 stop12h 00m
San Antonio
Fri 10/23
2:35 pm-10:40 pm
2 stops7h 05m
$366
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Thu 9/10
1:53 pm-10:44 pm
2 stops9h 51m
San Antonio
Fri 9/11
9:30 am-10:49 pm
2 stops12h 19m
$368
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Wed 9/2
7:00 am-11:52 am
1 stop5h 52m
San Antonio
Tue 9/8
5:30 pm-12:23 am
1 stop5h 53m
$383
KnoxvilleSan Antonio
TYS Knoxville McGhee Tyson - SAT San Antonio
TYSSAT
Knoxville McGhee Tyson
Tue 10/20
4:20 pm-9:30 pm
1 stop6h 10m
San Antonio
Fri 10/23
4:40 pm-10:40 pm
1 stop5h 00m
$383
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
TYS-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Antonio
How far ahead should I book a flight from Knoxville to San Antonio?
To ensure you get the cheapest price possible for a flight from Knoxville to San Antonio, you should look to book at least 90 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Knoxville to San Antonio?
Currently, January is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $290). Flying from Knoxville to San Antonio in July is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated August 18, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
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Knoxville and San Antonio flights
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Top 4 airlines flying from Knoxville to San Antonio
Discover the top 4 airlines that operate flights from Knoxville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$225 | Average$328 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$264 | Average$439 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$355 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$488 | FlexibilityNo cancel fee | On-time63% |