$129+ Cheap flights from Knoxville to San Antonio (TYS - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
May 19 — May 261
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to San Antonio
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Best
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Cheapest flights from Knoxville to San AntonioExplore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:32 pm
TYS
- SAT
1 stop23h 27m
Frontier
Thu 5/147:54 pm
SAT
- TYS
1 stop22h 39m
Frontier
Deal found 4/16![Frontier logo]()
$206
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:50 pm
TYS
- SAT
1 stop6h 25m
Southwest
Tue 5/1912:35 pm
SAT
- TYS
1 stop6h 05m
Southwest
Deal found 4/16![Southwest logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:32 pm
TYS
- SAT
1 stop23h 27m
Multiple Airlines
Mon 6/85:26 pm
SAT
- TYS
1 stop21h 46m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:19 pm
TYS
- SAT
1 stop4h 40m
American Airlines
Sun 5/245:00 am
SAT
- TYS
1 stop7h 02m
American Airlines
Deal found 4/16![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:09 pm
TYS
- SAT
1 stop6h 48m
American Airlines
Mon 5/115:09 pm
SAT
- TYS
1 stop5h 50m
American Airlines
Deal found 4/16![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:00 am
TYS
- SAT
1 stop6h 39m
American Airlines
Tue 5/194:28 pm
SAT
- TYS
1 stop6h 28m
American Airlines
Deal found 4/18![American Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:15 pm
TYS
- SAT
1 stop4h 44m
American Airlines
Sun 5/245:00 am
SAT
- TYS
1 stop7h 02m
American Airlines
Deal found 4/16![American Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:57 pm
TYS
- SAT
1 stop7h 31m
Delta
Tue 10/136:15 pm
SAT
- TYS
1 stop4h 31m
Delta
Deal found 4/16![Delta logo]()
$304
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:35 am
TYS
- SAT
1 stop5h 46m
Delta
Mon 7/64:12 pm
SAT
- TYS
1 stop6h 42m
Delta
Deal found 4/16![Delta logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:15 am
TYS
- SAT
1 stop10h 01m
Multiple Airlines
Mon 6/155:26 pm
SAT
- TYS
1 stop21h 46m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$311
Best flights from Knoxville to San AntonioDiscover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
Discover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/23:54 pm
TYS
- SAT
1 stop5h 47m
Delta
Sun 7/56:45 am
SAT
- TYS
1 stop7h 04m
Delta
Deal found 4/15![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:00 pm
TYS
- SAT
1 stop7h 05m
Southwest
Thu 6/2511:45 am
SAT
- TYS
2 stops8h 25m
Southwest
Deal found 4/14![Southwest logo]()
$408
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:20 am
TYS
- SAT
2 stops8h 19m
United Airlines
Sun 7/55:57 pm
SAT
- TYS
1 stop4h 15m
United Airlines
Deal found 4/15![United Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:01 pm
TYS
- SAT
1 stop5h 53m
United Airlines
Sun 5/105:30 am
SAT
- TYS
2 stops10h 24m
United Airlines
Deal found 4/15![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:40 am
TYS
- SAT
2 stops7h 45m
Southwest
Mon 6/1511:45 am
SAT
- TYS
2 stops8h 25m
Southwest
Deal found 4/16![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:05 am
TYS
- SAT
2 stops6h 05m
Southwest
Mon 5/411:10 am
SAT
- TYS
2 stops8h 10m
Southwest
Deal found 4/14![Southwest logo]()
$437
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:00 am
TYS
- SAT
2 stops14h 35m
United Airlines
Tue 5/1911:45 am
SAT
- TYS
2 stops8h 00m
United Airlines
Deal found 4/15![United Airlines logo]()
$443
Last-minute flights from Knoxville to San AntonioDiscover last-minute flight deals from Knoxville to San Antonio. Data last updated April 19, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Antonio. Data last updated April 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:54 pm
TYS
- SAT
1 stop6h 02m
American Airlines
Sat 5/97:00 am
SAT
- TYS
1 stop7h 17m
American Airlines
Deal found 4/14![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:09 pm
TYS
- SAT
1 stop6h 48m
American Airlines
Mon 5/115:09 pm
SAT
- TYS
1 stop5h 50m
American Airlines
Deal found 4/16![American Airlines logo]()
$291
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:32 pm
TYS
- SAT
1 stop23h 27m
Frontier
Thu 5/147:54 pm
SAT
- TYS
1 stop22h 39m
Frontier
Deal found 4/16![Frontier logo]()
$206
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:54 pm
TYS
- SAT
1 stop4h 58m
American Airlines
Sun 5/105:00 am
SAT
- TYS
1 stop4h 22m
American Airlines
Deal found 4/15![American Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:30 am
TYS
- SAT
1 stop9h 46m
Multiple Airlines
Thu 5/145:26 pm
SAT
- TYS
1 stop17h 59m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:50 pm
TYS
- SAT
1 stop6h 25m
Southwest
Tue 5/1912:35 pm
SAT
- TYS
1 stop6h 05m
Southwest
Deal found 4/16![Southwest logo]()
$257
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:00 am
TYS
- SAT
1 stop6h 39m
American Airlines
Tue 5/194:28 pm
SAT
- TYS
1 stop6h 28m
American Airlines
Deal found 4/18![American Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:19 pm
TYS
- SAT
1 stop4h 40m
American Airlines
Sun 5/245:00 am
SAT
- TYS
1 stop7h 02m
American Airlines
Deal found 4/16![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:15 pm
TYS
- SAT
1 stop4h 44m
American Airlines
Sun 5/245:00 am
SAT
- TYS
1 stop7h 02m
American Airlines
Deal found 4/16![American Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:00 am
TYS
- SAT
1 stop12h 59m
Multiple Airlines
Thu 6/47:54 pm
SAT
- TYS
2 stops26h 45m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$321
One-way flights from Knoxville to San AntonioSearch for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
Search for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:57 pm
TYS
- SAT
1 stop5h 54m
United Airlines
Deal found 4/18![United Airlines logo]()
$129
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:40 am
TYS
- SAT
1 stop4h 40m
Southwest
Deal found 4/15![Southwest logo]()
$165
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:45 pm
TYS
- SAT
1 stop6h 15m
Southwest
Deal found 4/15![Southwest logo]()
$170
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:40 am
TYS
- SAT
1 stop5h 03m
Delta
Deal found 4/18![Delta logo]()
$171
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:58 pm
TYS
- SAT
1 stop7h 03m
American Airlines
Deal found 4/17![American Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:20 pm
TYS
- SAT
2 stops38h 55m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$182
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:55 pm
TYS
- SAT
2 stops7h 50m
Southwest
Deal found 4/17![Southwest logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/214:05 pm
TYS
- SAT
3 stops51h 51m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$225
Find flight deals from Knoxville to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $206 (Frontier) |
One-way from | $129 (United Airlines) |
Popular in | June |
Cheapest in | July |
Average price | $332 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Thu 7/2
3:54 pm-8:41 pm
1 stop5h 47m
San Antonio
Sun 7/5
6:45 am-2:49 pm
1 stop7h 04m
$341
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sun 6/21
7:00 pm-1:05 am
1 stop7h 05m
San Antonio
Thu 6/25
11:45 am-9:10 pm
2 stops8h 25m
$408
Quickest round-trip
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Thu 7/2
8:20 am-3:39 pm
2 stops8h 19m
San Antonio
Sun 7/5
5:57 pm-11:12 pm
1 stop4h 15m
$414
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Fri 5/8
6:01 pm-10:54 pm
1 stop5h 53m
San Antonio
Sun 5/10
5:30 am-4:54 pm
2 stops10h 24m
$414
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Thu 6/11
6:40 am-1:25 pm
2 stops7h 45m
San Antonio
Mon 6/15
11:45 am-9:10 pm
2 stops8h 25m
$417
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Wed 4/29
7:05 am-12:10 pm
2 stops6h 05m
San Antonio
Mon 5/4
11:10 am-8:20 pm
2 stops8h 10m
$437
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Tue 5/12
7:00 am-8:35 pm
2 stops14h 35m
San Antonio
Tue 5/19
11:45 am-8:45 pm
2 stops8h 00m
$443
Cheapest one-way
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sat 7/11
5:57 pm-10:51 pm
1 stop5h 54m
$129
Quickest one-way
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Mon 6/22
6:40 am-10:20 am
1 stop4h 40m
$165
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sun 6/21
7:00 pm-1:05 am
1 stop7h 05m
$170
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
TYS-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Antonio
How far ahead should I book a flight from Knoxville to San Antonio?
Use this chart to determine the optimal time to book a round-trip flight from Knoxville to San Antonio. Price data was last updated on April 17, 2026.
To ensure you get the cheapest price possible for a flight from Knoxville to San Antonio, you should look to book at least 7 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Knoxville to San Antonio?
Currently, July is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $243). Flying from Knoxville to San Antonio in June is currently the most expensive (average of $523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated April 19, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Knoxville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Alternative routes for Knoxville to San Antonio
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Knoxville and San Antonio flights
Browse other Knoxville and San Antonio flight options. Last updated on April 19, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on April 19, 2026.
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Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 19, 2026.
Top 4 airlines flying from Knoxville to San Antonio
Discover the top 4 airlines that operate flights from Knoxville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$207 | Average$308 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$216 | Average$523 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$232 | Average$318 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$358 | FlexibilityNo cancel fee | On-time69% |