$129+ Cheap flights from Des Moines to San Antonio (DSM - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Aug 19 — Aug 261
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to San Antonio with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from Des Moines to San AntonioExplore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 20, 2026.
Explore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 20, 2026.
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:19 pm
DSM
- SAT
1 stop5h 12m
Frontier
Sun 9/68:26 pm
SAT
- DSM
1 stop17h 08m
Frontier
Deal found 7/18![Frontier logo]()
$298
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 pm
DSM
- SAT
1 stop5h 58m
Delta
Wed 11/186:45 am
SAT
- DSM
1 stop6h 42m
Delta
Deal found 7/14![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:35 pm
DSM
- SAT
2 stops7h 41m
United Airlines
Sat 9/56:30 am
SAT
- DSM
1 stop5h 48m
United Airlines
Deal found 7/15![United Airlines logo]()
$322
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:50 pm
DSM
- SAT
2 stops7h 05m
Southwest
Mon 8/315:35 am
SAT
- DSM
2 stops8h 10m
Southwest
Deal found 7/16![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:13 pm
DSM
- SAT
1 stop4h 44m
American Airlines
Thu 9/102:58 pm
SAT
- DSM
1 stop4h 00m
American Airlines
Deal found 7/18![American Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- SAT
1 stop7h 25m
Southwest
Thu 8/206:00 am
SAT
- DSM
2 stops7h 45m
Southwest
Deal found 7/14![Southwest logo]()
$334
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:10 pm
DSM
- SAT
2 stops8h 10m
Southwest
Sat 9/126:20 am
SAT
- DSM
2 stops7h 50m
Southwest
Deal found 7/17![Southwest logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:22 pm
DSM
- SAT
1 stop4h 28m
American Airlines
Mon 8/241:33 pm
SAT
- DSM
1 stop5h 46m
American Airlines
Deal found 7/19![American Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:20 pm
DSM
- SAT
1 stop7h 45m
Southwest
Wed 10/216:50 am
SAT
- DSM
2 stops7h 30m
Southwest
Deal found 7/17![Southwest logo]()
$346
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- SAT
2 stops7h 05m
Southwest
Wed 8/191:30 pm
SAT
- DSM
2 stops8h 25m
Southwest
Deal found 7/15![Southwest logo]()
$358
Best flights from Des Moines to San AntonioDiscover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 20, 2026.
Discover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 20, 2026.
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
DSM
- SAT
1 stop5h 52m
United Airlines
Thu 8/206:30 am
SAT
- DSM
1 stop7h 46m
United Airlines
Deal found 7/14![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:40 pm
DSM
- SAT
2 stops7h 00m
Southwest
Sat 9/55:50 am
SAT
- DSM
2 stops8h 20m
Southwest
Deal found 7/16![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:20 pm
DSM
- SAT
1 stop7h 30m
United Airlines
Fri 8/216:30 am
SAT
- DSM
1 stop5h 50m
United Airlines
Deal found 7/15![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/132:25 pm
DSM
- SAT
2 stops9h 00m
Southwest
Thu 8/206:00 am
SAT
- DSM
2 stops7h 45m
Southwest
Deal found 7/14![Southwest logo]()
$370
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:20 pm
DSM
- SAT
2 stops7h 19m
United Airlines
Sun 9/69:30 am
SAT
- DSM
1 stop4h 44m
United Airlines
Deal found 7/19![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:40 am
DSM
- SAT
1 stop7h 05m
Southwest
Sun 11/1511:55 am
SAT
- DSM
1 stop6h 40m
Southwest
Deal found 7/17![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:40 am
DSM
- SAT
1 stop8h 00m
Southwest
Mon 8/246:00 am
SAT
- DSM
2 stops7h 45m
Southwest
Deal found 7/19![Southwest logo]()
$392
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:35 pm
DSM
- SAT
2 stops9h 09m
United Airlines
Wed 9/1612:00 pm
SAT
- DSM
2 stops9h 28m
United Airlines
Deal found 7/16![United Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:50 pm
DSM
- SAT
1 stop7h 25m
Southwest
Fri 8/213:25 pm
SAT
- DSM
2 stops6h 45m
Southwest
Deal found 7/15![Southwest logo]()
$398
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:50 pm
DSM
- SAT
1 stop7h 20m
Southwest
Thu 10/85:40 am
SAT
- DSM
1 stop7h 40m
Southwest
Deal found 7/16![Southwest logo]()
$402
Last-minute flights from Des Moines to San AntonioDiscover last-minute flight deals from Des Moines to San Antonio. Data last updated July 20, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Antonio. Data last updated July 20, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:40 pm
DSM
- SAT
2 stops8h 15m
Southwest
Thu 8/132:15 pm
SAT
- DSM
1 stop7h 55m
Southwest
Deal found 7/14![Southwest logo]()
$384
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
DSM
- SAT
1 stop5h 52m
United Airlines
Thu 8/206:30 am
SAT
- DSM
1 stop7h 46m
United Airlines
Deal found 7/14![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- SAT
1 stop7h 25m
Southwest
Wed 8/193:15 pm
SAT
- DSM
2 stops6h 40m
Southwest
Deal found 7/15![Southwest logo]()
$322
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- SAT
1 stop7h 25m
Southwest
Thu 8/206:00 am
SAT
- DSM
2 stops7h 45m
Southwest
Deal found 7/14![Southwest logo]()
$334
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:22 pm
DSM
- SAT
1 stop4h 28m
American Airlines
Mon 8/241:33 pm
SAT
- DSM
1 stop5h 46m
American Airlines
Deal found 7/19![American Airlines logo]()
$341
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:20 pm
DSM
- SAT
1 stop7h 30m
United Airlines
Fri 8/216:30 am
SAT
- DSM
1 stop5h 50m
United Airlines
Deal found 7/15![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:50 pm
DSM
- SAT
1 stop7h 25m
Southwest
Mon 8/241:00 pm
SAT
- DSM
2 stops9h 10m
Southwest
Deal found 7/17![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:50 pm
DSM
- SAT
2 stops7h 05m
Southwest
Mon 8/315:35 am
SAT
- DSM
2 stops8h 10m
Southwest
Deal found 7/16![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:28 pm
DSM
- SAT
1 stop6h 22m
American Airlines
Sun 9/65:30 pm
SAT
- DSM
1 stop5h 37m
American Airlines
Deal found 7/16![American Airlines logo]()
$363
One-way flights from Des Moines to San AntonioSearch for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated July 20, 2026.
Search for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated July 20, 2026.
This Expedia deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm
DSM
- SAT
1 stop5h 12m
Frontier
Deal found 7/18![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:19 pm
DSM
- SAT
1 stop28h 35m
Frontier
Deal found 7/16![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- SAT
1 stop23h 16m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$171
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:50 pm
DSM
- SAT
2 stops7h 05m
Southwest
Deal found 7/18![Southwest logo]()
$176
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:00 am
DSM
- SAT
1 stop6h 47m
United Airlines
Deal found 7/15![United Airlines logo]()
$204
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:25 pm
DSM
- SAT
2 stops7h 40m
Southwest
Deal found 7/15![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:43 am
DSM
- SAT
3 stops37h 03m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$221
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:54 pm
DSM
- SAT
1 stop5h 33m
Delta
Deal found 7/15![Delta logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
- SAT
1 stop22h 36m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$236
Find flight deals from Des Moines to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $298 (CheapOair) |
One-way from | $129 (Expedia) |
Popular in | June |
Cheapest in | August |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
Use the filters below to find and compare flights from Des Moines to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Thu 8/13
6:00 am-11:52 am
1 stop5h 52m
San Antonio
Thu 8/20
6:30 am-2:16 pm
1 stop7h 46m
$317
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Tue 9/1
2:40 pm-9:40 pm
2 stops7h 00m
San Antonio
Sat 9/5
5:50 am-2:10 pm
2 stops8h 20m
$358
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Mon 8/17
3:20 pm-10:50 pm
1 stop7h 30m
San Antonio
Fri 8/21
6:30 am-12:20 pm
1 stop5h 50m
$362
Quickest round-trip
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Fri 9/4
3:20 pm-10:39 pm
2 stops7h 19m
San Antonio
Sun 9/6
9:30 am-2:14 pm
1 stop4h 44m
$367
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Thu 8/13
2:25 pm-11:25 pm
2 stops9h 00m
San Antonio
Thu 8/20
6:00 am-1:45 pm
2 stops7h 45m
$370
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Thu 11/12
6:40 am-1:45 pm
1 stop7h 05m
San Antonio
Sun 11/15
11:55 am-6:35 pm
1 stop6h 40m
$374
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Mon 8/17
5:40 am-1:40 pm
1 stop8h 00m
San Antonio
Mon 8/24
6:00 am-1:45 pm
2 stops7h 45m
$392
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Mon 8/17
3:50 pm-11:15 pm
1 stop7h 25m
San Antonio
Fri 8/21
3:25 pm-10:10 pm
2 stops6h 45m
$398
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Sun 10/4
4:50 pm-12:10 am
1 stop7h 20m
San Antonio
Thu 10/8
5:40 am-1:20 pm
1 stop7h 40m
$402
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Sat 9/12
1:35 pm-10:44 pm
2 stops9h 09m
San Antonio
Wed 9/16
12:00 pm-9:28 pm
2 stops9h 28m
$407
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Des Moines to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Antonio in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Des Moines with our price prediction graph.
DSM-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to San Antonio
What is the cheapest month to book a flight from Des Moines to San Antonio?
Currently, August is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $321). Flying from Des Moines to San Antonio in June is currently the most expensive (average of $760). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated July 20, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to San Antonio. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 4 airlines flying from Des Moines to San Antonio
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$213 | Average$387 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$262 | Average$390 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$456 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$359 | Average$421 | FlexibilityNo cancel fee | On-time63% |