$102+ Cheap flights from Des Moines to San Antonio (DSM - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Mar 19 — Mar 261
1 adult, Economy
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Find cheap flights from Des Moines to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to San Antonio
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Best
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Cheapest flights from Des Moines to San AntonioExplore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 17, 2026.
Explore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 17, 2026.
This CheapOair deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:21 pm
DSM
- SAT
1 stop27h 56m
Frontier
Wed 3/256:45 am
SAT
- DSM
1 stop12h 31m
Frontier
Deal found 2/14![Frontier logo]()
$206
This CheapOair deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:20 pm
DSM
- SAT
1 stop24h 19m
Frontier
Sun 5/103:14 pm
SAT
- DSM
1 stop22h 15m
Frontier
Deal found 2/16![Frontier logo]()
$213
This CheapOair deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- SAT
1 stop26h 56m
Frontier
Sat 3/146:45 am
SAT
- DSM
1 stop12h 31m
Frontier
Deal found 2/14![Frontier logo]()
$225
This CheapOair deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:20 pm
DSM
- SAT
1 stop24h 19m
Frontier
Sun 4/263:14 pm
SAT
- DSM
1 stop22h 15m
Frontier
Deal found 2/17![Frontier logo]()
$226
This CheapOair deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:27 pm
DSM
- SAT
1 stop24h 10m
Frontier
Thu 3/58:25 pm
SAT
- DSM
1 stop22h 51m
Frontier
Deal found 2/14![Frontier logo]()
$236
This CheapOair deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- SAT
1 stop11h 45m
Frontier
Wed 3/116:45 am
SAT
- DSM
1 stop12h 31m
Frontier
Deal found 2/15![Frontier logo]()
$237
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:00 pm
DSM
- SAT
1 stop11h 59m
American Airlines
Tue 5/56:14 pm
SAT
- DSM
1 stop5h 35m
American Airlines
Deal found 2/15![American Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- SAT
1 stop11h 45m
Multiple Airlines
Wed 3/1110:26 am
SAT
- DSM
2 stops33h 50m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:17 pm
DSM
- SAT
1 stop21h 24m
Frontier
Wed 2/256:12 pm
SAT
- DSM
1 stop24h 30m
Frontier
Deal found 2/15![Frontier logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/227:45 pm
DSM
- SAT
1 stop23h 52m
Frontier
Wed 2/256:12 pm
SAT
- DSM
1 stop24h 30m
Frontier
Deal found 2/15![Frontier logo]()
$302
Best flights from Des Moines to San AntonioDiscover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 17, 2026.
Discover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 17, 2026.
This CheapOair deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:21 pm
DSM
- SAT
1 stop27h 56m
Frontier
Wed 3/256:45 am
SAT
- DSM
1 stop12h 31m
Frontier
Deal found 2/14![Frontier logo]()
$206
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:44 pm
DSM
- SAT
1 stop5h 46m
Delta
Tue 5/55:20 am
SAT
- DSM
1 stop5h 45m
Delta
Deal found 2/13![Delta logo]()
$317
This CheapOair deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:20 pm
DSM
- SAT
1 stop24h 19m
Frontier
Sun 5/103:14 pm
SAT
- DSM
1 stop22h 15m
Frontier
Deal found 2/16![Frontier logo]()
$213
This CheapOair deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:20 pm
DSM
- SAT
1 stop24h 19m
Frontier
Sun 4/263:14 pm
SAT
- DSM
1 stop22h 15m
Frontier
Deal found 2/15![Frontier logo]()
$226
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:35 am
DSM
- SAT
1 stop7h 07m
Delta
Tue 4/75:10 am
SAT
- DSM
1 stop5h 38m
Delta
Deal found 2/14![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:23 pm
DSM
- SAT
1 stop5h 07m
Delta
Sat 5/212:26 pm
SAT
- DSM
1 stop5h 19m
Delta
Deal found 2/16![Delta logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:21 pm
DSM
- SAT
1 stop27h 56m
Frontier
Sun 4/54:30 pm
SAT
- DSM
2 stops26h 44m
Frontier
Deal found 2/14![Frontier logo]()
$316
Last-minute flights from Des Moines to San AntonioDiscover last-minute flight deals from Des Moines to San Antonio. Data last updated February 17, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Antonio. Data last updated February 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/227:45 pm
DSM
- SAT
1 stop23h 52m
Frontier
Wed 2/256:12 pm
SAT
- DSM
1 stop24h 30m
Frontier
Deal found 2/15![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:17 pm
DSM
- SAT
1 stop21h 24m
Frontier
Wed 2/256:12 pm
SAT
- DSM
1 stop24h 30m
Frontier
Deal found 2/15![Frontier logo]()
$291
This CheapOair deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:27 pm
DSM
- SAT
1 stop24h 10m
Frontier
Thu 3/58:25 pm
SAT
- DSM
1 stop22h 51m
Frontier
Deal found 2/14![Frontier logo]()
$236
This CheapOair deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- SAT
1 stop26h 56m
Frontier
Sat 3/146:45 am
SAT
- DSM
1 stop12h 31m
Frontier
Deal found 2/14![Frontier logo]()
$225
This CheapOair deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- SAT
1 stop11h 45m
Frontier
Wed 3/116:45 am
SAT
- DSM
1 stop12h 31m
Frontier
Deal found 2/15![Frontier logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- SAT
1 stop11h 45m
Multiple Airlines
Wed 3/1110:26 am
SAT
- DSM
2 stops33h 50m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$282
This CheapOair deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:21 pm
DSM
- SAT
1 stop27h 56m
Frontier
Wed 3/256:45 am
SAT
- DSM
1 stop12h 31m
Frontier
Deal found 2/14![Frontier logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:21 pm
DSM
- SAT
1 stop27h 56m
Frontier
Sun 4/54:30 pm
SAT
- DSM
2 stops26h 44m
Frontier
Deal found 2/14![Frontier logo]()
$316
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:25 pm
DSM
- SAT
1 stop5h 22m
Delta
Tue 4/710:50 am
SAT
- DSM
1 stop5h 43m
Delta
Deal found 2/13![Delta logo]()
$317
One-way flights from Des Moines to San AntonioSearch for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated February 17, 2026.
Search for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated February 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/168:21 pm
DSM
- SAT
1 stop27h 56m
Frontier
Deal found 2/17![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:20 pm
DSM
- SAT
1 stop23h 59m
Frontier
Deal found 2/15![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:48 pm
DSM
- SAT
2 stops27h 30m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$172
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1510:55 am
DSM
- SAT
1 stop6h 21m
Delta
Deal found 2/17![Delta logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:17 pm
DSM
- SAT
2 stops38h 10m
Multiple Airlines
Deal found 2/17![Multiple Airlines logo]()
$196
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/154:40 pm
DSM
- SAT
2 stops8h 20m
Southwest
Deal found 2/17![Southwest logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:56 pm
DSM
- SAT
3 stops51h 17m
Multiple Airlines
Deal found 2/17![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:21 pm
DSM
- SAT
1 stop27h 56m
Frontier
Deal found 2/15![Frontier logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:32 pm
DSM
- SAT
2 stops36h 34m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$488
Find flight deals from Des Moines to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $206 (CheapOair) |
One-way from | $122 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $439 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
Use the filters below to find and compare flights from Des Moines to San Antonio that are best for you.
Fly from
Des Moines
Fly to
San Antonio
Route
Depart
Return
Price
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Fri 3/20
8:21 pm-12:17 am
1 stop27h 56m
San Antonio
Wed 3/25
6:45 am-7:16 pm
1 stop12h 31m
$206
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Fri 5/8
2:20 pm-2:39 pm
1 stop24h 19m
San Antonio
Sun 5/10
3:14 pm-1:29 pm
1 stop22h 15m
$213
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Fri 4/24
2:20 pm-2:39 pm
1 stop24h 19m
San Antonio
Sun 4/26
3:14 pm-1:29 pm
1 stop22h 15m
$226
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Mon 3/30
8:21 pm-12:17 am
1 stop27h 56m
San Antonio
Sun 4/5
4:30 pm-7:14 pm
2 stops26h 44m
$316
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Sat 5/2
2:44 pm-8:30 pm
1 stop5h 46m
San Antonio
Tue 5/5
5:20 am-11:05 am
1 stop5h 45m
$317
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Tue 3/31
5:35 am-12:42 pm
1 stop7h 07m
San Antonio
Tue 4/7
5:10 am-10:48 am
1 stop5h 38m
$317
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Tue 4/28
4:23 pm-9:30 pm
1 stop5h 07m
San Antonio
Sat 5/2
12:26 pm-5:45 pm
1 stop5h 19m
$317
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Mon 3/16
8:21 pm-12:17 am
1 stop27h 56m
$102
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Mon 5/11
2:20 pm-2:19 pm
1 stop23h 59m
$122
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Mon 5/11
6:48 pm-10:18 pm
2 stops27h 30m
$172
Showing 1-10 of 16 results
Compare providers for flights from Des Moines to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Antonio in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Des Moines with our price prediction graph.
DSM-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to San Antonio
How far ahead should I book a flight from Des Moines to San Antonio?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to San Antonio. Price data was last updated on February 13, 2026.
The price you pay for your flight from Des Moines to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 63 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to San Antonio?
Currently, March is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $82). Flying from Des Moines to San Antonio in November is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated February 17, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to San Antonio. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Des Moines to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Des Moines and San Antonio flights
Browse other Des Moines and San Antonio flight options. Last updated on February 17, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on February 17, 2026.
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Top 4 airlines flying from Des Moines to San Antonio
Discover the top 4 airlines that operate flights from Des Moines to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$361 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$266 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$457 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$316 | Average$421 | FlexibilityNo cancel fee | On-time63% |