$208+ Cheap flights from Des Moines (DSM) to Playa del Carmen, Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CUN
Apr 18 — Apr 251
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Playa del Carmen with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Playa del Carmen
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Best
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One-way
Cheapest flights from Des Moines to Playa del CarmenExplore the most affordable flight options available from Des Moines to Playa del Carmen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 19, 2026.
Explore the most affordable flight options available from Des Moines to Playa del Carmen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 19, 2026.
This Frontier deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
DSM
- CUN
1 stop15h 41m
Frontier
Tue 5/123:39 pm
CUN
- DSM
1 stop21h 52m
Frontier
Deal found 3/17![Frontier logo]()
$359
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:44 am
DSM
- CUN
1 stop6h 24m
American Airlines
Wed 4/2212:05 pm
CUN
- DSM
1 stop11h 54m
American Airlines
Deal found 3/16![American Airlines logo]()
$395
This Expedia deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:14 pm
DSM
- CUN
1 stop15h 10m
Frontier
Mon 4/1310:13 am
CUN
- DSM
1 stop9h 01m
Frontier
Deal found 3/15![Frontier logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:36 pm
DSM
- CUN
1 stop20h 54m
Multiple Airlines
Wed 4/1511:09 am
CUN
- DSM
2 stops28h 51m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$431
This Aeromexico deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:45 am
DSM
- CUN
2 stops19h 26m
Aeromexico
Tue 5/56:42 pm
CUN
- DSM
2 stops23h 03m
Aeromexico
Deal found 3/15![Aeromexico logo]()
$434
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:05 pm
DSM
- CUN
1 stop16h 52m
American Airlines
Wed 5/202:35 pm
CUN
- DSM
1 stop7h 43m
American Airlines
Deal found 3/17![American Airlines logo]()
$443
Best flights from Des Moines to Playa del CarmenDiscover carefully curated flight deals from Des Moines to Playa del Carmen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 19, 2026.
Discover carefully curated flight deals from Des Moines to Playa del Carmen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 19, 2026.
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:20 am
DSM
- CUN
1 stop5h 58m
United Airlines
Tue 5/51:43 pm
CUN
- DSM
1 stop9h 02m
United Airlines
Deal found 3/17![United Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:00 am
DSM
- CUN
2 stops13h 15m
Delta
Tue 5/129:14 am
CUN
- DSM
2 stops13h 18m
Delta
Deal found 3/17![Delta logo]()
$468
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:30 am
DSM
- CUN
2 stops8h 48m
United Airlines
Sat 4/183:43 pm
CUN
- DSM
1 stop7h 59m
United Airlines
Deal found 3/15![United Airlines logo]()
$492
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:01 am
DSM
- CUN
2 stops13h 15m
Delta
Fri 5/1512:45 pm
CUN
- DSM
1 stop9h 47m
Delta
Deal found 3/15![Delta logo]()
$540
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:30 pm
DSM
- CUN
1 stop15h 26m
Delta
Tue 7/288:00 am
CUN
- DSM
1 stop9h 42m
Delta
Deal found 3/14![Delta logo]()
$559
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:25 pm
DSM
- CUN
2 stops13h 41m
United Airlines
Fri 5/155:22 pm
CUN
- DSM
2 stops16h 01m
United Airlines
Deal found 3/18![United Airlines logo]()
$603
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:20 am
DSM
- CUN
1 stop6h 27m
Delta
Fri 7/318:00 am
CUN
- DSM
2 stops12h 45m
Delta
Deal found 3/14![Delta logo]()
$564
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:00 am
DSM
- CUN
2 stops12h 40m
Delta
Sat 5/29:12 am
CUN
- DSM
2 stops13h 22m
Delta
Deal found 3/14![Delta logo]()
$578
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:30 pm
DSM
- CUN
2 stops17h 31m
Delta
Wed 8/512:29 pm
CUN
- DSM
2 stops20h 50m
Delta
Deal found 3/18![Delta logo]()
$580
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:20 am
DSM
- CUN
1 stop6h 27m
Delta
Fri 7/318:00 am
CUN
- DSM
2 stops12h 45m
Delta
Deal found 3/14![Delta logo]()
$594
Last-minute flights from Des Moines to Playa del CarmenDiscover last-minute flight deals from Des Moines to Playa del Carmen. Data last updated March 19, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Playa del Carmen. Data last updated March 19, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:21 pm
DSM
- CUN
1 stop14h 55m
Frontier
Wed 3/259:53 am
CUN
- DSM
1 stop9h 23m
Frontier
Deal found 3/16![Frontier logo]()
$465
This Orbitz deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:21 pm
DSM
- CUN
1 stop19h 56m
Frontier
Mon 3/3010:08 am
CUN
- DSM
1 stop9h 08m
Frontier
Deal found 3/16![Frontier logo]()
$460
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:35 am
DSM
- CUN
1 stop10h 10m
Delta
Wed 4/156:01 am
CUN
- DSM
2 stops11h 44m
Delta
Deal found 3/14![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:44 am
DSM
- CUN
1 stop8h 08m
American Airlines
Tue 4/1411:01 am
CUN
- DSM
2 stops12h 48m
American Airlines
Deal found 3/17![American Airlines logo]()
$457
This Expedia deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:14 pm
DSM
- CUN
1 stop15h 10m
Frontier
Mon 4/1310:13 am
CUN
- DSM
1 stop9h 01m
Frontier
Deal found 3/15![Frontier logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:36 pm
DSM
- CUN
1 stop20h 54m
Multiple Airlines
Wed 4/1511:09 am
CUN
- DSM
2 stops28h 51m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:44 am
DSM
- CUN
1 stop6h 24m
American Airlines
Wed 4/2212:05 pm
CUN
- DSM
1 stop11h 54m
American Airlines
Deal found 3/16![American Airlines logo]()
$395
This Aeromexico deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:44 pm
DSM
- CUN
2 stops21h 49m
Aeromexico
Wed 4/228:00 am
CUN
- DSM
1 stop9h 45m
Aeromexico
Deal found 3/16![Aeromexico logo]()
$461
One-way flights from Des Moines to Playa del CarmenSearch for one-way flight options from Des Moines to Playa del Carmen. Find affordable one-way fares based on user searches. Data last updated March 19, 2026.
Search for one-way flight options from Des Moines to Playa del Carmen. Find affordable one-way fares based on user searches. Data last updated March 19, 2026.
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:05 pm
DSM
- CUN
1 stop16h 00m
American Airlines
Deal found 3/18![American Airlines logo]()
$208
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:23 pm
DSM
- CUN
2 stops19h 12m
Delta
Deal found 3/18![Delta logo]()
$212
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:00 am
DSM
- CUN
1 stop7h 50m
American Airlines
Deal found 3/14![American Airlines logo]()
$213
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:15 am
DSM
- CUN
2 stops13h 59m
Delta
Deal found 3/18![Delta logo]()
$214
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:26 am
DSM
- CUN
2 stops9h 50m
Delta
Deal found 3/14![Delta logo]()
$270
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:35 am
DSM
- CUN
2 stops8h 50m
Southwest
Deal found 3/18![Southwest logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:30 am
DSM
- CUN
3 stops45h 41m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:41 am
DSM
- CUN
3 stops29h 19m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$672
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:00 am
DSM
- CUN
3 stops34h 00m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$736
Find flight deals from Des Moines to Playa del Carmen
Keep the following information in mind while searching for Des Moines to Playa del Carmen flight deals. Data was last updated March 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (Frontier) |
One-way from | $208 (American Airlines) |
Popular in | July |
Cheapest in | September |
Average price | $659 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Playa del Carmen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
Use the filters below to find and compare flights from Des Moines to Playa del Carmen that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Tue 4/28
8:20 am-2:18 pm
1 stop5h 58m
Cancun
Tue 5/5
1:43 pm-10:45 pm
1 stop9h 02m
$447
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Mon 5/4
7:00 am-8:15 pm
2 stops13h 15m
Cancun
Tue 5/12
9:14 am-10:32 pm
2 stops13h 18m
$468
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Tue 4/14
5:30 am-2:18 pm
2 stops8h 48m
Cancun
Sat 4/18
3:43 pm-11:42 pm
1 stop7h 59m
$492
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Fri 5/8
7:01 am-8:16 pm
2 stops13h 15m
Cancun
Fri 5/15
12:45 pm-10:32 pm
1 stop9h 47m
$540
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Sat 7/25
6:30 pm-9:56 am
1 stop15h 26m
Cancun
Tue 7/28
8:00 am-5:42 pm
1 stop9h 42m
$559
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Sun 7/26
6:20 am-12:47 pm
1 stop6h 27m
Cancun
Fri 7/31
8:00 am-8:45 pm
2 stops12h 45m
$564
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Sat 4/25
7:00 am-7:40 pm
2 stops12h 40m
Cancun
Sat 5/2
9:12 am-10:34 pm
2 stops13h 22m
$578
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Sat 8/1
6:30 pm-12:01 pm
2 stops17h 31m
Cancun
Wed 8/5
12:29 pm-9:19 am
2 stops20h 50m
$580
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Thu 7/23
6:20 am-12:47 pm
1 stop6h 27m
Cancun
Fri 7/31
8:00 am-8:45 pm
2 stops12h 45m
$594
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Fri 5/8
8:25 pm-10:06 am
2 stops13h 41m
Cancun
Fri 5/15
5:22 pm-9:23 am
2 stops16h 01m
$603
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Playa del Carmen
Have a flexible travel schedule? Discover the best time to fly to Playa del Carmen from Des Moines with our price prediction graph.
DSM-CUN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Playa del Carmen
DSM-PL9
DSM-CUN
How far ahead should I book a flight from Des Moines to Playa del Carmen?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Playa del Carmen. Price data was last updated on March 13, 2026.
The price you pay for your flight from Des Moines to Playa del Carmen may vary depending on when you book. For the best chance of a lower fare, look to book 25 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Playa del Carmen?
Currently, April is the cheapest month in which you can book a flight from Des Moines to Playa del Carmen (average of $321). Flying from Des Moines to Playa del Carmen in August is currently the most expensive (average of $527). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Playa del Carmen
Get insights into the airlines that provide service to Playa del Carmen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Playa del Carmen. Reviews last updated March 19, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Playa del Carmen have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Playa del Carmen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Playa del Carmen by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Playa del Carmen, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Playa del Carmen flights
Browse other Des Moines and Playa del Carmen flight options. Last updated on March 19, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on March 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Playa del Carmen flights
Consider these flights traveling from Des Moines to Playa del Carmen.
Top 5 airlines flying from Des Moines to Playa del Carmen
Discover the top 5 airlines that operate flights from Des Moines to Playa del Carmen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$233 | Average$480 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$397 | Average$610 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$422 | Average$586 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$457 | Average$582 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$569 | Average$694 | FlexibilityNo cancel fee | On-time63% |