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$490+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amIND - PTY
1 stop7h 53mAmerican Airlines
Thu 1/84:50 pmPTY - IND
1 stop17h 11mAmerican Airlines
Deal found 12/2$580
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:00 amIND - PTY
1 stop7h 45mUnited Airlines
Wed 12/178:55 amPTY - IND
1 stop11h 09mUnited Airlines
Deal found 12/3$591
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:14 pmIND - PTY
1 stop23h 53mUnited Airlines
Thu 12/1811:35 amPTY - IND
1 stop12h 09mUnited Airlines
Deal found 12/3$602
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:50 amIND - PTY
1 stop7h 48mUnited Airlines
Tue 12/168:55 amPTY - IND
1 stop11h 09mUnited Airlines
Deal found 12/3$612
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:14 pmIND - PTY
1 stop21h 31mUnited Airlines
Tue 12/94:41 pmPTY - IND
2 stops18h 42mUnited Airlines
Deal found 12/3$627
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:00 amIND - PTY
1 stop8h 21mDelta
Wed 12/103:46 pmPTY - IND
1 stop8h 40mDelta
Deal found 12/3$632
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:15 amIND - PTY
2 stops12h 23mUnited Airlines
Sun 12/711:55 pmPTY - IND
2 stops13h 22mUnited Airlines
Deal found 12/2$636

Find flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$490
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$1,037
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
Search Deals
From Indianapolis to Panama
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($109 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($38 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 1/27

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Wed 2/4

2:27 pm-11:59 pm

1 stop9h 32m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 3/16

6:45 am-1:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Sun 3/22

7:55 am-8:48 pm

1 stop11h 53m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 1/26

11:40 am-7:38 pm

1 stop7h 58m

Panama City Tocumen Intl

Fri 1/30

8:55 am-11:30 pm

1 stop14h 35m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

6:58 pm-2:22 pm

2 stops20h 24m

Panama City Tocumen Intl

Wed 4/1

1:44 pm-1:10 pm

2 stops22h 26m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 1/18

3:38 pm-2:45 pm

2 stops23h 07m

Panama City Tocumen Intl

Wed 1/28

4:41 pm-11:32 am

2 stops18h 51m

$514

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $382). Flying from Indianapolis to Panama in December is currently the most expensive (average of $584). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PA?

Find hourly flight availability from Indianapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

When flying from Indianapolis to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 43% versus a flight in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 4, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,066 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Indianapolis to Panama?

    For as low as $490, American Airlines can have you in Panama from Indianapolis in 7h 27m. Airlines will cover a distance of 2158 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $382). Flying from Indianapolis to Panama in December is currently the most expensive (average of $584). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Midway to San Salvador flights
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Louisville to Liberia flights
Dayton to San José flights
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Cincinnati to San Salvador flights
Indianapolis to Managua flights
Louisville to Philip S.W.Goldson flights
Indianapolis to San Salvador flights
Midway to San Pedro Sula flights
Midway to Coxen Hole flights
Indianapolis to Coxen Hole flights
Cincinnati to Managua flights
Louisville to Guatemala City flights
Fort Wayne to San José flights
Dayton to Liberia flights
Dayton to Panama City flights
Dayton to Philip S.W.Goldson flights
Evansville to Panama City flights
Cincinnati to Coxen Hole flights
Louisville to San Salvador flights
Louisville to Managua flights
Kalamazoo to San José flights
Fort Wayne to San Salvador flights
South Bend to Panama City flights

Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$469Average$673FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$616FlexibilityNo cancel feeOn-time69%
DeltaCheapest$489Average$646FlexibilityNo cancel feeOn-timeN/A

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