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$258+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$489
(Delta)

One-way from

$258
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$569
From Indianapolis to Panama
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One-way flight from Indianapolis to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/46:00 amIND - PTY
1 stop7h 56mDelta
jue. 11/63:21 pmPTY - IND
1 stop9h 01mDelta
Deal found 9/10$489
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/46:00 amIND - PTY
2 stops13h 38mUnited Airlines
jue. 11/64:41 pmPTY - IND
2 stops18h 32mUnited Airlines
Deal found 9/10$494
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/46:00 amIND - PTY
1 stop7h 49mAmerican Airlines
sáb. 11/82:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Deal found 9/10$509
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/85:22 pmIND - PTY
1 stop26h 16mUnited Airlines
mié. 11/128:55 amPTY - IND
1 stop14h 49mUnited Airlines
Deal found 9/10$519
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/87:12 pmIND - PTY
1 stop18h 37mAmerican Airlines
mié. 11/122:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Deal found 9/11$521
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/226:15 amIND - PTY
1 stop8h 35mUnited Airlines
jue. 10/307:55 amPTY - IND
1 stop14h 49mUnited Airlines
Deal found 9/11$529
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/196:51 pmIND - PTY
1 stop19h 05mDelta
mié. 10/292:21 pmPTY - IND
1 stop9h 01mDelta
Deal found 9/11$538
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/317:07 pmIND - PTY
1 stop19h 56mAmerican Airlines
lun. 11/32:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Deal found 9/11$541
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/197:59 pmIND - PTY
1 stop17h 57mDelta
jue. 10/302:21 pmPTY - IND
1 stop19h 12mDelta
Deal found 9/11$546
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/247:00 amIND - PTY
1 stop6h 56mDelta
mar. 10/282:21 pmPTY - IND
1 stop9h 01mDelta
Deal found 9/11$549

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

mar. 11/4

6:00 am-1:56 pm

1 stop7h 56m

Panama City Tocumen Intl

jue. 11/6

3:21 pm-12:22 am

1 stop9h 01m

$489

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

mar. 11/4

6:00 am-7:38 pm

2 stops13h 38m

Panama City Tocumen Intl

jue. 11/6

4:41 pm-11:13 am

2 stops18h 32m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

mar. 11/4

4:12 pm-1:49 pm

2 stops21h 37m

Panama City Tocumen Intl

vie. 11/7

2:49 pm-9:47 am

2 stops18h 58m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

mar. 3/10

6:45 am-1:45 pm

1 stop8h 00m

Panama City Tocumen Intl

jue. 3/12

3:40 pm-9:21 am

2 stops16h 41m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

vie. 11/14

6:00 am-7:59 pm

1 stop13h 59m

Panama City Tocumen Intl

lun. 11/17

3:37 pm-12:26 am

1 stop8h 49m

$509

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

mar. 11/4

4:40 pm-1:49 pm

2 stops21h 09m

Panama City Tocumen Intl

sáb. 11/8

2:49 pm-10:20 am

2 stops19h 31m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

vie. 11/14

5:44 pm-2:45 pm

2 stops21h 01m

Panama City Tocumen Intl

lun. 11/17

4:41 pm-10:53 am

1 stop18h 12m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

mar. 10/21

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

mar. 11/4

8:55 am-11:18 pm

2 stops14h 23m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

vie. 11/7

7:00 pm-1:49 pm

2 stops18h 49m

$258

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

vie. 11/7

6:45 am-7:38 pm

1 stop12h 53m

$272

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PA?

Find hourly flight availability from Indianapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Indianapolis to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated septiembre 11, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Indianapolis to Panama?

    For as low as $489, Delta can have you in Panama from Indianapolis in 7h 56m. Airlines will cover a distance of 2158 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Dayton to Panama City flights
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Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$655FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$600FlexibilityNo cancel feeOn-time69%
DeltaCheapest$477Average$557FlexibilityNo cancel feeOn-timeN/A

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