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$249+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated August 18, 2025.

Round-trip from

$387
(Avianca Connect)

One-way from

$249
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$630
From Indianapolis to Panama
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One-way flight from Indianapolis to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This Avianca Connect deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:35 amIND - PTY
2 stops18h 25mMultiple Airlines
Tue 11/112:55 amPTY - IND
2 stops20h 01mMultiple Airlines
Deal found 8/16$387
This Mytrip deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:35 amIND - PTY
2 stops26h 15mMultiple Airlines
Wed 11/122:55 amPTY - IND
3 stops20h 01mMultiple Airlines
Deal found 8/17$485
This Trip.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:45 amIND - PTY
1 stop12h 53mUnited Airlines
Thu 11/138:55 amPTY - IND
1 stop14h 49mUnited Airlines
Deal found 8/17$486
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amIND - PTY
1 stop7h 56mDelta
Wed 10/292:21 pmPTY - IND
1 stop9h 01mDelta
Deal found 8/18$489
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:00 amIND - PTY
1 stop8h 14mUnited Airlines
Wed 10/293:41 pmPTY - IND
2 stops23h 02mUnited Airlines
Deal found 8/18$494
This Avianca Connect deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:45 amIND - PTY
2 stops19h 25mMultiple Airlines
Tue 9/233:20 amPTY - IND
2 stops15h 27mMultiple Airlines
Deal found 8/18$498
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:45 amIND - PTY
1 stop12h 53mUnited Airlines
Wed 11/1210:00 amPTY - IND
1 stop9h 56mUnited Airlines
Deal found 8/18$509
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:00 amIND - PTY
2 stops13h 37mUnited Airlines
Thu 10/910:00 amPTY - IND
1 stop12h 30mUnited Airlines
Deal found 8/17$519
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:55 pmIND - PTY
1 stop20h 08mAmerican Airlines
Fri 10/103:15 pmPTY - IND
1 stop8h 20mAmerican Airlines
Deal found 8/16$521

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 11/8

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

Tue 11/11

2:55 am-10:56 pm

2 stops20h 01m

$387

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 11/10

6:35 am-8:50 am

2 stops26h 15m

Panama City Tocumen Intl

Wed 11/12

2:55 am-10:56 pm

3 stops20h 01m

$485

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 11/10

6:45 am-7:38 pm

1 stop12h 53m

Panama City Tocumen Intl

Thu 11/13

8:55 am-11:44 pm

1 stop14h 49m

$486

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 10/22

7:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Wed 10/29

2:21 pm-12:22 am

1 stop9h 01m

$489

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/4

6:00 am-1:36 pm

1 stop7h 36m

Panama City Tocumen Intl

Fri 11/7

2:43 pm-11:54 pm

1 stop9h 11m

$489

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 10/22

7:15 am-6:37 pm

2 stops12h 22m

Panama City Tocumen Intl

Wed 10/29

3:41 pm-3:43 pm

2 stops23h 02m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 10/12

6:42 pm-4:30 pm

3 stops46h 48m

$249

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 10/12

7:00 am-12:56 pm

1 stop6h 56m

$252

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 10/12

6:56 pm-2:03 pm

2 stops20h 07m

$252

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PA?

Find hourly flight availability from Indianapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

When flying from Indianapolis to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 18, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,925 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Indianapolis to Panama?

    For as low as $489, United Airlines can have you in Panama from Indianapolis in 6h 56m. Airlines will cover a distance of 2158 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to San José flights
O'Hare Intl to Panama City flights
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Louisville to San José flights
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Dayton to San José flights
Cincinnati to Guatemala City flights
Midway to San Salvador flights
Fort Wayne to Panama City flights
Louisville to Liberia flights
Cincinnati to Coxen Hole flights
Louisville to Philip S.W.Goldson flights
Indianapolis to Managua flights
Midway to San Pedro Sula flights
Indianapolis to San Pedro Sula flights
Dayton to Panama City flights
South Bend to Panama City flights
South Bend to San Salvador flights
Midway to Coxen Hole flights
Louisville to Panama City flights
Dayton to Philip S.W.Goldson flights
Louisville to Guatemala City flights
Fort Wayne to San Salvador flights
Cincinnati to San Salvador flights
Kalamazoo to Liberia flights
Indianapolis to Coxen Hole flights
Kalamazoo to Panama City flights
Louisville to San Salvador flights
South Bend to San José flights

Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$650FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$600FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$565FlexibilityNo cancel feeOn-timeN/A

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