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$232+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$490
(Delta)

One-way from

$232
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$629
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
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From Indianapolis to Panama
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One-way flight from Indianapolis to Panama
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Highest demand for flights based on searches. 9% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:29 pmIND - PTY
2 stops22h 16mUnited Airlines
Sat 12/274:41 pmPTY - IND
1 stop18h 09mUnited Airlines
Deal found 11/4$534
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:45 amIND - PTY
1 stop8h 00mUnited Airlines
Wed 12/310:00 amPTY - IND
1 stop10h 27mUnited Airlines
Deal found 11/4$550
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:45 amIND - PTY
1 stop12h 53mUnited Airlines
Tue 12/24:41 pmPTY - IND
1 stop18h 12mUnited Airlines
Deal found 11/5$570
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:22 pmIND - PTY
2 stops20h 20mAmerican Airlines
Sat 12/274:55 pmPTY - IND
2 stops17h 30mAmerican Airlines
Deal found 11/4$604
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:00 amIND - PTY
1 stop7h 49mAmerican Airlines
Wed 11/122:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Deal found 11/5$612
This Avianca Connect deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:30 amIND - PTY
2 stops19h 30mMultiple Airlines
Fri 12/122:55 amPTY - IND
2 stops18h 40mMultiple Airlines
Deal found 11/6$627
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 amIND - PTY
1 stop7h 49mAmerican Airlines
Wed 11/122:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Deal found 11/6$632
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:51 amIND - PTY
3 stops27h 04mMultiple Airlines
Wed 12/32:55 pmPTY - IND
2 stops29h 06mMultiple Airlines
Deal found 11/4$635

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 1/12

9:00 am-7:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Mon 1/19

4:41 pm-10:48 am

1 stop18h 07m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/3

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-11:57 pm

1 stop8h 37m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-9:00 am

1 stop17h 40m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 3/4

9:00 am-7:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Wed 3/11

7:55 am-11:27 pm

1 stop14h 32m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/3

6:45 am-2:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Tue 3/10

7:55 am-8:47 pm

1 stop11h 52m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 2/19

6:07 am-8:02 pm

2 stops13h 55m

Panama City Tocumen Intl

Tue 2/24

10:00 am-11:44 pm

2 stops13h 44m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

6:45 am-4:07 pm

1 stop10h 22m

Panama City Tocumen Intl

Thu 3/12

3:41 pm-10:59 am

2 stops18h 18m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 12/29

8:11 pm-3:54 pm

2 stops19h 43m

$232

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 1/15

9:00 am-5:07 pm

1 stop8h 07m

$237

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 12/29

5:05 pm-7:38 pm

1 stop26h 33m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $382). Flying from Indianapolis to Panama in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PA?

Find hourly flight availability from Indianapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

When flying from Indianapolis to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 43% versus a flight in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 6, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,007 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Indianapolis to Panama?

    For as low as $490, United Airlines can have you in Panama from Indianapolis in 8h 02m. Airlines will cover a distance of 2158 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $382). Flying from Indianapolis to Panama in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$672FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$606FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$614FlexibilityNo cancel feeOn-timeN/A

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