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$222+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Jun 21 — Jun 281
Sat 6/21
Sat 6/28
1 adult, Economy
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Cheap flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated June 16, 2025.

Round-trip from

$396
(Delta)

One-way from

$222
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$586
From Indianapolis to Panama
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One-way flight from Indianapolis to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.

This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amIND - PTY
1 stop7h 47mDelta
Wed 10/292:12 pmPTY - IND
1 stop8h 45mDelta
Deal found 6/16$396
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/223:50 pmIND - PTY
2 stops21h 35mAmerican Airlines
Wed 10/291:50 pmPTY - IND
2 stops17h 33mAmerican Airlines
Deal found 6/14$401
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amIND - PTY
1 stop8h 55mUnited Airlines
Mon 11/38:55 amPTY - IND
1 stop14h 49mUnited Airlines
Deal found 6/16$461
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/46:30 amIND - PTY
1 stop14h 49mMultiple Airlines
Tue 8/512:03 pmPTY - IND
1 stop10h 05mMultiple Airlines
Deal found 6/16$462
This Avianca deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/25:45 amIND - PTY
3 stops31h 50mAvianca
Tue 8/51:30 pmPTY - IND
3 stops20h 05mAvianca
Deal found 6/16$675

Cheapflights Fare Finder

Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 10/22

6:00 am-12:47 pm

1 stop7h 47m

Panama City Tocumen Intl

Wed 10/29

2:12 pm-11:57 pm

1 stop8h 45m

$396

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 10/22

3:50 pm-12:25 pm

2 stops21h 35m

Panama City Tocumen Intl

Wed 10/29

1:50 pm-8:23 am

2 stops17h 33m

$401

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 10/31

6:00 am-1:55 pm

1 stop8h 55m

Panama City Tocumen Intl

Mon 11/3

8:55 am-11:44 pm

1 stop14h 49m

$461

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 8/4

6:30 am-8:19 pm

1 stop14h 49m

Panama City Tocumen Intl

Tue 8/5

12:03 pm-11:08 pm

1 stop10h 05m

$462

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 8/2

5:45 am-12:35 pm

2 stops31h 50m

Panama City Tocumen Intl

Tue 8/5

1:30 pm-10:35 am

3 stops20h 05m

$675

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 7/30

6:30 am-12:35 pm

3 stops31h 05m

$222

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 7/30

6:00 am-4:12 pm

2 stops11h 12m

$232

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/7

6:00 am-1:52 pm

1 stop7h 52m

$252

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/7

8:15 pm-3:20 pm

2 stops19h 05m

$258

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/15

Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PA?

Find hourly flight availability from Indianapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2025.

When flying from Indianapolis to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated June 16, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Indianapolis to Panama. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,963 reviews
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,801 reviews
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,346 reviews
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • What are the cheapest airlines to fly from Indianapolis to Panama one-way?

    One-way options have recently been found by users for as low as $232 on United Airlines. Other airlines that offer cheap prices include Delta from $252 and American Airlines from $258 one-way.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$449Average$572FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$462Average$626FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$588FlexibilityNo cancel feeOn-time69%

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