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$191+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$469
(Delta)

One-way from

$191
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$549
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
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From Indianapolis to Panama
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One-way flight from Indianapolis to Panama
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Highest demand for flights based on searches. 4% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Avianca Connect deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/308:15 amIND - PTY
2 stops13h 55mMultiple Airlines
Thu 6/53:20 amPTY - IND
2 stops18h 55mMultiple Airlines
Deal found 4/30$466
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:10 amIND - PTY
1 stop6h 37mDelta
Wed 10/292:12 pmPTY - IND
1 stop7h 04mDelta
Deal found 4/30$469
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:18 pmIND - PTY
2 stops17h 07mAmerican Airlines
Wed 10/291:50 pmPTY - IND
2 stops21h 04mAmerican Airlines
Deal found 4/30$474
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:55 pmIND - PTY
1 stop24h 43mUnited Airlines
Mon 11/39:30 amPTY - IND
1 stop13h 47mUnited Airlines
Deal found 4/30$499
This Avianca deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/210:13 amIND - PTY
2 stops14h 57mAvianca
Mon 5/53:25 amPTY - IND
2 stops30h 03mAvianca
Deal found 4/30$861

Cheapflights Fare Finder

Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 5/30

8:15 am-9:10 pm

2 stops13h 55m

Panama City Tocumen Intl

Thu 6/5

3:20 am-11:15 pm

2 stops18h 55m

$466

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 10/22

7:10 am-12:47 pm

1 stop6h 37m

Panama City Tocumen Intl

Wed 10/29

2:12 pm-10:16 pm

1 stop7h 04m

$469

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 10/22

8:18 pm-12:25 pm

2 stops17h 07m

Panama City Tocumen Intl

Wed 10/29

1:50 pm-11:54 am

2 stops21h 04m

$474

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 6/13

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

Mon 6/16

10:55 pm-12:56 pm

2 stops13h 01m

$554

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 5/25

10:12 am-4:30 pm

2 stops31h 18m

Panama City Tocumen Intl

Tue 6/24

3:20 am-10:35 am

2 stops30h 15m

$951

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 5/21

8:15 am-4:30 pm

3 stops33h 15m

$191

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 6/5

7:05 pm-1:00 pm

1 stop18h 55m

$233

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 5/19

6:00 am-12:48 pm

1 stop7h 48m

$242

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PA?

Find hourly flight availability from Indianapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Indianapolis to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 1, 2025.
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$630FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$588FlexibilityNo cancel feeOn-time69%
DeltaCheapest$469Average$585FlexibilityNo cancel feeOn-timeN/A

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