HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$272+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indianapolis to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$490
(Delta)

One-way from

$272
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$640
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
Search Deals
From Indianapolis to Panama
Search Deals
One-way flight from Indianapolis to Panama
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($64 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:45 amIND - PTY
1 stop12h 53mUnited Airlines
Thu 12/411:35 amPTY - IND
1 stop11h 34mUnited Airlines
Deal found 10/12$510
This Avianca Connect deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/110:15 amIND - PTY
2 stops15h 45mMultiple Airlines
Thu 11/62:55 amPTY - IND
2 stops17h 09mMultiple Airlines
Deal found 10/12$519
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:00 amIND - PTY
1 stop7h 43mAmerican Airlines
Mon 12/12:43 pmPTY - IND
1 stop9h 13mAmerican Airlines
Deal found 10/12$530
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:45 amIND - PTY
1 stop8h 00mUnited Airlines
Mon 11/174:41 pmPTY - IND
1 stop18h 12mUnited Airlines
Deal found 10/11$550
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:47 pmIND - PTY
2 stops18h 02mAmerican Airlines
Wed 11/122:49 pmPTY - IND
2 stops17h 56mAmerican Airlines
Deal found 10/12$554
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:00 amIND - PTY
1 stop7h 56mDelta
Sat 11/83:21 pmPTY - IND
1 stop9h 01mDelta
Deal found 10/11$570
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:15 amIND - PTY
2 stops12h 23mUnited Airlines
Mon 11/34:41 pmPTY - IND
2 stops20h 31mUnited Airlines
Deal found 10/12$574
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:30 amIND - PTY
1 stop8h 33mAmerican Airlines
Fri 10/313:15 pmPTY - IND
2 stops19h 53mAmerican Airlines
Deal found 10/11$579
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:47 pmIND - PTY
2 stops18h 00mAmerican Airlines
Sat 12/204:55 pmPTY - IND
2 stops20h 42mAmerican Airlines
Deal found 10/12$589

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

7:10 am-12:55 pm

1 stop6h 45m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-11:57 pm

1 stop8h 37m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 3/12

9:00 am-6:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Mon 3/16

3:41 pm-11:00 am

1 stop18h 19m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

11:35 am-6:38 pm

1 stop8h 03m

Panama City Tocumen Intl

Thu 3/12

3:41 pm-10:59 am

2 stops18h 18m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 2/26

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

Sat 2/28

2:55 am-10:56 pm

2 stops20h 01m

$500

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 11/27

11:45 am-7:38 pm

1 stop7h 53m

Panama City Tocumen Intl

Tue 12/2

10:00 am-8:22 pm

1 stop10h 22m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/7

4:49 pm-1:49 pm

2 stops21h 00m

$272

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/7

6:45 am-7:38 pm

1 stop12h 53m

$272

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/11

Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $382). Flying from Indianapolis to Panama in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PA?

Find hourly flight availability from Indianapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

When flying from Indianapolis to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 43% versus a flight in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 13, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,974 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,045 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Indianapolis to Panama?

    For as low as $490, Delta can have you in Panama from Indianapolis in 6h 45m. Airlines will cover a distance of 2158 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $382). Flying from Indianapolis to Panama in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to San José flights
O'Hare Intl to Guatemala City flights
O'Hare Intl to Panama City flights
O'Hare Intl to Liberia flights
O'Hare Intl to Philip S.W.Goldson flights
Midway to San José flights
Midway to Guatemala City flights
O'Hare Intl to San Salvador flights
Indianapolis to Panama City flights
O'Hare Intl to Managua flights
Midway to Liberia flights
Indianapolis to Guatemala City flights
Midway to Panama City flights
Cincinnati to Panama City flights
Midway to Philip S.W.Goldson flights
O'Hare Intl to San Pedro Sula flights
Cincinnati to San José flights
Indianapolis to San José flights
Louisville to Panama City flights
Cincinnati to Liberia flights
Indianapolis to Liberia flights
O'Hare Intl to Coxen Hole flights
Cincinnati to Guatemala City flights
Evansville to Panama City flights
Cincinnati to Philip S.W.Goldson flights
Indianapolis to San Salvador flights
Louisville to San José flights
Louisville to Liberia flights
Indianapolis to Philip S.W.Goldson flights
Louisville to Philip S.W.Goldson flights
Midway to San Salvador flights
Indianapolis to San Pedro Sula flights
Midway to San Pedro Sula flights
Fort Wayne to Guatemala City flights
Cincinnati to San Pedro Sula flights
Louisville to Managua flights
Louisville to San Salvador flights
Indianapolis to Managua flights
Dayton to San José flights
Louisville to Guatemala City flights
Midway to Managua flights
Dayton to Liberia flights
Dayton to Guatemala City flights
Cincinnati to San Salvador flights
South Bend to San Salvador flights
Fort Wayne to Panama City flights
Fort Wayne to San José flights
South Bend to Panama City flights
Midway to Coxen Hole flights
Indianapolis to Coxen Hole flights

Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$671FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$607FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$617FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.