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$230+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$472
(Avianca Connect)

One-way from

$230
(Avianca)

Popular in

December

Cheapest in

September

Average price

$584
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
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From Indianapolis to Panama
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One-way flight from Indianapolis to Panama
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Highest demand for flights based on searches. 22% potential increase in price ($191 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Avianca Connect deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:28 amIND - PTY
2 stops15h 32mMultiple Airlines
Sun 3/12:55 amPTY - IND
2 stops19h 53mMultiple Airlines
Deal found 1/7$472
This Avianca deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:30 pmIND - PTY
2 stops16h 00mAvianca
Fri 4/243:50 pmPTY - IND
2 stops17h 32mAvianca
Deal found 1/7$487
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:37 amIND - PTY
1 stop8h 01mUnited Airlines
Wed 4/13:30 pmPTY - IND
1 stop18h 16mUnited Airlines
Deal found 1/8$491
This Avianca deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/247:43 pmIND - PTY
2 stops19h 12mAvianca
Wed 1/287:50 pmPTY - IND
2 stops14h 38mAvianca
Deal found 1/8$493
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:02 pmIND - PTY
1 stop24h 32mMultiple Airlines
Wed 2/252:55 amPTY - IND
2 stops16h 28mMultiple Airlines
Deal found 1/7$498
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:38 pmIND - PTY
2 stops20h 02mAmerican Airlines
Fri 4/31:40 pmPTY - IND
2 stops20h 02mAmerican Airlines
Deal found 1/5$500
This Ovago deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:00 amIND - PTY
1 stop23h 10mCopa Airlines
Wed 4/17:55 amPTY - IND
1 stop12h 37mCopa Airlines
Deal found 1/6$501
This Gurufare deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:00 amIND - PTY
1 stop14h 02mMultiple Airlines
Thu 4/29:45 amPTY - IND
1 stop11h 00mMultiple Airlines
Deal found 1/7$510
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:08 amIND - PTY
1 stop6h 55mDelta
Thu 3/192:28 pmPTY - IND
1 stop17h 47mDelta
Deal found 1/6$511

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 2/26

9:28 am-1:00 am

2 stops15h 32m

Panama City Tocumen Intl

Sun 3/1

2:55 am-10:48 pm

2 stops19h 53m

$472

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/24

9:00 am-4:07 pm

1 stop8h 07m

Panama City Tocumen Intl

Wed 4/1

10:00 am-9:32 pm

1 stop10h 32m

$491

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 4/13

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 4/16

2:20 pm-12:23 am

1 stop9h 03m

$491

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 1/24

7:43 pm-2:55 pm

2 stops19h 12m

Panama City Tocumen Intl

Wed 1/28

7:50 pm-10:28 am

2 stops14h 38m

$493

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/24

5:27 pm-2:20 pm

2 stops21h 53m

Panama City Tocumen Intl

Wed 4/1

3:51 pm-1:10 pm

2 stops20h 19m

$495

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 4/13

9:24 am-6:37 pm

2 stops10h 13m

Panama City Tocumen Intl

Thu 4/16

3:30 pm-11:17 am

2 stops18h 47m

$495

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 2/26

6:00 am-5:07 pm

2 stops11h 07m

Panama City Tocumen Intl

Mon 3/2

4:41 pm-10:48 am

1 stop18h 07m

$495

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 1/20

6:00 am-2:00 pm

3 stops32h 00m

$237

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 1/19

6:43 pm-1:00 am

2 stops30h 17m

$250

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 1/20

9:00 am-7:38 pm

1 stop10h 38m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/5

Showing 1-10 of 11 results
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Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $382). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 8, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,025 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,025 reviews
Delta
7.9
Good
8,025 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,139 reviews
Delta
7.9
Good
8,025 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,094 reviews
Delta
7.9
Good
8,025 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Indianapolis to Panama?

    For as low as $491, United Airlines can have you in Panama from Indianapolis in 7h 55m. Airlines will cover a distance of 2158 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $382). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Cincinnati to Coxen Hole flights
Evansville to Panama City flights
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Louisville to San Salvador flights
Midway to Managua flights

Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$663FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$621FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$625FlexibilityNo cancel feeOn-timeN/A

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