HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$460+ Cheap flights from Asheville (AVL) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
AVL — PTY
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Asheville to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Asheville to Panama

Keep the following information in mind while searching for Asheville to Panama flight deals. Data was last updated October 27, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$460
(American Airlines)

Popular in

September

Cheapest in

April

Average price

$478
Provider with most accurate pricing for Asheville Regional-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Asheville Regional-Panama City Tocumen Intl flights.
Search Deals
From Asheville Regional to Panama
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($135 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($62 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Asheville to Panama

Cheapest flights from Asheville to Panama
Explore the most affordable flight options available from Asheville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:58 pmAVL - PTY
2 stops23h 49mAmerican Airlines
Wed 12/172:50 pmPTY - AVL
2 stops20h 25mAmerican Airlines
Deal found 10/26$460
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:31 pmAVL - PTY
3 stops26h 24mMultiple Airlines
Wed 12/179:45 amPTY - AVL
3 stops35h 54mMultiple Airlines
Deal found 10/26$714
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:18 pmAVL - PTY
2 stops19h 35mAmerican Airlines
Sat 12/272:53 pmPTY - AVL
2 stops17h 32mAmerican Airlines
Deal found 10/24$730
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:30 amAVL - PTY
2 stops17h 30mMultiple Airlines
Fri 12/262:55 amPTY - AVL
2 stops20h 19mMultiple Airlines
Deal found 10/24$841

Cheapflights Fare Finder

 
Customize your flight search to find flights from Asheville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Asheville to Panama that are best for you.

Fly from

Asheville

Fly to

Panama

Route

Depart

Return

Price

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Wed 12/10

1:58 pm-1:47 pm

2 stops23h 49m

Panama City Tocumen Intl

Wed 12/17

2:50 pm-11:15 am

2 stops20h 25m

$460

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Sun 1/25

9:00 am-8:50 am

3 stops47h 50m

Panama City Tocumen Intl

Thu 1/29

11:25 am-10:37 pm

2 stops11h 12m

$571

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Sat 3/14

7:28 pm-2:20 pm

2 stops19h 52m

Panama City Tocumen Intl

Sat 3/21

1:50 pm-12:04 pm

2 stops21h 14m

$590

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Sun 1/25

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 1/29

3:20 pm-10:41 pm

1 stop7h 21m

$685

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Sun 12/21

6:18 pm-1:53 pm

2 stops19h 35m

Panama City Tocumen Intl

Sat 12/27

2:53 pm-8:25 am

2 stops17h 32m

$730

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Wed 12/10

4:31 pm-6:55 pm

3 stops26h 24m

Panama City Tocumen Intl

Wed 12/17

7:50 pm-12:55 pm

2 stops17h 05m

$744

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Best time to book a flight from Asheville to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Asheville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Asheville to Panama

What is the cheapest month to book a flight from Asheville to Panama?

Currently, November is the cheapest month in which you can book a flight from Asheville to Panama (average of $228). Flying from Asheville to Panama in January is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from AVL to PA?

Find hourly flight availability from Asheville to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

It’s typically best to fly out from Asheville to Panama at noon. Doing so could potentially save you 40% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 27, 2025.
Read through reviews of airlines operating flights from Asheville to Panama, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,997 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,997 reviews
Delta
7.9
Good
7,997 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,030 reviews
Delta
7.9
Good
7,997 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Asheville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Asheville to Panama?

    Asheville Regional (AVL) is the airport you will fly out of if you book a flight from Asheville to Panama. It is only a 10.9 mi journey to Asheville Regional (AVL) from Asheville’s city center.

  • How long is the flight from Asheville to Panama?

    For as low as $460, American Airlines can have you in Panama from Asheville in 23h 49m. The distance from Asheville to Panama is about 1831 mi.

  • Can I find deals for flights from Asheville to Panama that include hotel bookings?

    Yes. In addition to deals on Asheville to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Asheville to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Asheville to Panama.

  • Can I find deals for business class flights from Asheville to Panama?

    Yes. Cheapflights offers flight deals from Asheville to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Asheville to Panama?

    Currently, November is the cheapest month in which you can book a flight from Asheville to Panama (average of $228). Flying from Asheville to Panama in January is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Asheville to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to San José flights
Raleigh to San José flights
Charlotte to San Salvador flights
Raleigh to Panama City flights
Raleigh to San Salvador flights
Charlotte to Panama City flights
Raleigh to Liberia flights
Charlotte to Philip S.W.Goldson flights
Charlotte to Liberia flights
Raleigh to Philip S.W.Goldson flights
Raleigh to Guatemala City flights
Greensboro to San Salvador flights
Charlotte to Guatemala City flights
Greensboro to Panama City flights
Greensboro to San José flights
Asheville to Liberia flights
Raleigh to San Pedro Sula flights
Wilmington to San José flights
Norfolk to Liberia flights
Charlotte to Managua flights
Norfolk to San José flights
Charlotte to San Pedro Sula flights
Raleigh to Coxen Hole flights
Myrtle Beach to Panama City flights
Knoxville to San José flights
Knoxville to Panama City flights
Norfolk to San Salvador flights
Greensboro to Guatemala City flights
Wilmington to Liberia flights
Asheville to Philip S.W.Goldson flights
Asheville to San José flights
Charlotte to Coxen Hole flights
Wilmington to Panama City flights
Myrtle Beach to San José flights
Fayetteville to San José flights
Knoxville to Managua flights
Raleigh to Managua flights
Asheville to San Salvador flights
Norfolk to Panama City flights
Norfolk to Guatemala City flights
Asheville to Panama City flights
Knoxville to Liberia flights
Greensboro to Philip S.W.Goldson flights
Blountville to San Pedro Sula flights
Knoxville to Philip S.W.Goldson flights
Norfolk to Philip S.W.Goldson flights
Asheville to Guatemala City flights
Knoxville to San Salvador flights
Greensboro to Liberia flights
Fayetteville to Panama City flights

Top 2 airlines flying from Asheville to Panama

Discover the top 2 airlines that operate flights from Asheville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$423Average$520FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$445Average$574FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.