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Panama City

$189+ Cheap flights from Quito (UIO) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — PTY
oct. 25 — nov. 11
sáb. 10/25
sáb. 11/1
1 adult, Economy
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Cheapflights Tip: The best prices from Quito Mariscal Sucr to Panama City Tocumen Intl are usually found in February or January, booked 67 days in advance, depart on a Sunday or Wednesday and return on a Monday

Cheap flight deals from Quito to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 25, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$397
(Priceline)

One-way from

$233
(Mytrip)

Popular in

September

Cheapest in

February

Average price

$427

Good round-trip deal

$341 or less

Good one-way deal

$261 or less
Provider with most accurate pricing for Quito Mariscal Sucr-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Quito Mariscal Sucr-Panama City Tocumen Intl flights.
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From Quito Mariscal Sucr to Panama City Tocumen Intl
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One-way flight from Quito Mariscal Sucr to Panama City Tocumen Intl
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Highest demand for flights based on searches. 9% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Quito Mariscal Sucr to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Quito Mariscal Sucr to Panama City Tocumen Intl.
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Find flight deals from Quito to Panama City

Cheapest flights from Quito to Panama City
Explore the most affordable flight options available from Quito to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 25, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/16:15 pmUIO - PTY
1 stop6h 30mAvianca
mié. 10/811:00 amPTY - UIO
1 stop6h 05mAvianca
Deal found 9/25$393
This Copa Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/156:29 pmUIO - PTY
Nonstop1h 55mCopa Airlines
lun. 10/2010:31 pmPTY - UIO
Nonstop2h 01mCopa Airlines
Deal found 9/25$399
This Priceline deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/207:55 amUIO - PTY
2 stops8h 35mAvianca
jue. 10/302:55 pmPTY - UIO
1 stop8h 55mAvianca
Deal found 9/25$405
This Copa Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/66:29 pmUIO - PTY
Nonstop1h 55mCopa Airlines
vie. 10/103:28 pmPTY - UIO
Nonstop2h 03mCopa Airlines
Deal found 9/25$411
This Avianca deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/216:30 amUIO - PTY
2 stops10h 00mAvianca
vie. 10/312:55 amPTY - UIO
1 stop10h 15mAvianca
Deal found 9/23$414
This Priceline deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2210:30 amUIO - PTY
2 stops10h 40mAvianca
jue. 10/235:25 pmPTY - UIO
2 stops13h 25mAvianca
Deal found 9/25$423
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/33:50 pmUIO - PTY
1 stop8h 55mAvianca
dom. 10/53:20 amPTY - UIO
1 stop11h 20mAvianca
Deal found 9/24$424
This Priceline deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/136:00 amUIO - PTY
2 stops10h 30mAvianca
dom. 10/1911:00 amPTY - UIO
1 stop11h 25mAvianca
Deal found 9/24$430
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/297:45 amUIO - PTY
2 stops8h 45mAvianca
vie. 10/311:00 amPTY - UIO
2 stops10h 32mAvianca
Deal found 9/24$432

Cheapflights Fare Finder

 
Customize your flight search to find flights from Quito to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 25, 2025.
Use the filters below to find and compare flights from Quito to Panama City that are best for you.

Fly from

Quito

Fly to

Panama City

Route

Depart

Return

Price

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

jue. 10/16

6:29 pm-8:24 pm

Nonstop1h 55m

Panama City Tocumen Intl

dom. 10/19

10:25 am-12:27 pm

Nonstop2h 02m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

vie. 10/10

6:29 pm-8:24 pm

Nonstop1h 55m

Panama City Tocumen Intl

dom. 10/12

10:25 am-12:27 pm

Nonstop2h 02m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

mié. 10/15

3:17 pm-5:11 pm

Nonstop1h 54m

Panama City Tocumen Intl

dom. 10/19

10:25 am-12:27 pm

Nonstop2h 02m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

mié. 10/22

6:29 pm-8:24 pm

Nonstop1h 55m

Panama City Tocumen Intl

jue. 10/23

10:25 am-12:27 pm

Nonstop2h 02m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

sáb. 10/18

3:17 pm-5:11 pm

Nonstop1h 54m

Panama City Tocumen Intl

sáb. 10/25

12:10 pm-2:13 pm

Nonstop2h 03m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

lun. 10/13

6:29 pm-8:24 pm

Nonstop1h 55m

Panama City Tocumen Intl

dom. 10/19

10:25 am-12:27 pm

Nonstop2h 02m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

vie. 10/10

6:29 pm-8:24 pm

Nonstop1h 55m

Panama City Tocumen Intl

lun. 10/13

12:10 pm-2:13 pm

Nonstop2h 03m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

jue. 10/23

3:10 am-5:05 am

Nonstop1h 55m

Panama City Tocumen Intl

dom. 10/26

10:48 am-12:50 pm

Nonstop2h 02m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

jue. 10/23

3:17 pm-5:11 pm

Nonstop1h 54m

Panama City Tocumen Intl

dom. 10/26

10:48 am-12:50 pm

Nonstop2h 02m

$399

QuitoPanama City

UIO - PTY

UIOPTY

Quito Mariscal Sucr

lun. 10/20

6:00 am-4:30 pm

2 stops10h 30m

$190

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/25

Showing 1-10 of 17 results
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Compare providers for flights from Quito to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Quito to Panama City in September.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Quito-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Quito-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Quito-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Quito-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Quito-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Quito to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Quito with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Quito to Panama City

How far ahead should I book a flight from Quito to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Quito to Panama City. Price data was last updated on September 19, 2025.

To ensure you get the cheapest price possible for a flight from Quito to Panama City, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Quito to Panama City?

Currently, October is the cheapest month in which you can book a flight from Quito to Panama City (average of $478). Flying from Quito to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from UIO to PTY?

Find hourly flight availability from Quito to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 25, 2025.

A simple way to save on the total cost of your ticket is to fly from Quito to Panama City in the evening. If you’re flexible enough to do this you can expect to save up to 20% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Quito to Panama City?

Use this chart to determine the cheapest time to fly round-trip from Quito to Panama City. Price data was last updated on September 21, 2025.

Travelers seeking maximum savings on their Quito to Panama City flight should consider departing on Sunday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated septiembre 25, 2025.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Quito to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,539 reviews

Comfort

7.4

Boarding

7.8

Overall

7.6

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,539 reviews
Copa Airlines
7.6
Good
1,539 reviews

Comfort

7.4

Boarding

7.8

Overall

7.6

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.7
Okay
2,442 reviews
Copa Airlines
7.6
Good
1,539 reviews

Comfort

7.4

Boarding

7.8

Overall

7.6

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Quito to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Quito to Panama City?

    If you wish to fly to Panama City from Quito, then you need to book flights from Quito Mariscal Sucr to Panama City Tocumen Intl. There are 10 flights from Mariscal Sucr (UIO) to Tocumen Intl (PTY) per day to choose from. Flights to Panama City from Mariscal Sucr are available from 2 different airlines, which means you should have some options if you want to compare airfare deals. 1h 54m is how long a nonstop flight from Quito to Panama City Tocumen Intl typically takes.

  • How popular is this Quito to Panama City flight route?

    The Quito Mariscal Sucr to Panama City Tocumen Intl flight path was viewed by 25 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Quito to Panama City?

    For as low as $399, Copa Airlines can have you in Panama City from Quito in 1h 55m. Quito and Panama City are separated by a distance of 639 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from Quito to Panama City round-trip?

    Currently priced at $251, Avianca will fly you from Quito to Panama City and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Copa Airlines for as low as $312. Avianca is currently priced 31% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Quito to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Quito to Panama City on time: Copa Airlines (90%), KLM (85%), Air France (83%).

  • What are the cheapest flights from Quito to Panama City?

    Looking at all options, your cheapest flight can be booked for $175. While the most popular route (Quito Mariscal Sucr - Panama City Tocumen Intl) can be booked for $381 on average, our data indicates $452 when flying from Quito to Panama City.

  • Can I find deals for flights from Quito to Panama City that include hotel bookings?

    Yes. In addition to deals on Quito to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Panama City.

  • Can I find deals for business class flights from Quito to Panama City?

    Yes. Cheapflights offers flight deals from Quito to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Quito to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Quito to Panama City (average of $478). Flying from Quito to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Quito to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Guayaquil to Panama City flights

Top 2 airlines flying from Quito to Panama City

Discover the top 2 airlines that operate flights from Quito to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$251Average$361FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$312Average$427FlexibilityNo cancel feeOn-time70%

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