$242+ Cheap flights from Portland (PDX) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — PTY
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Panama City
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Best
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Cheapest flights from Portland to Panama CityExplore the most affordable flight options available from Portland to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Portland to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:00 pm -
1 stop12h 13m
Thu 11/53:13 pm -
1 stop11h 46m
Deal found 9/4![American Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:15 pm -
2 stops21h 23m
Mon 12/1411:35 am -
1 stop14h 33m
Deal found 9/7![United Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:21 pm -
2 stops18h 51m
Fri 12/2511:35 am -
1 stop10h 52m
Deal found 9/5![United Airlines logo]()
$583
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:57 pm -
1 stop22h 48m
Wed 11/118:55 am -
1 stop17h 20m
Deal found 9/4![United Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:59 pm -
1 stop12h 15m
Thu 2/2511:35 am -
1 stop14h 37m
Deal found 9/4![United Airlines logo]()
$595
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:26 pm -
2 stops21h 12m
Sat 11/214:41 pm -
1 stop22h 32m
Deal found 9/3![United Airlines logo]()
$608
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:59 pm -
1 stop12h 15m
Tue 3/28:55 am -
2 stops16h 43m
Deal found 9/3![United Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:25 pm -
2 stops20h 37m
Wed 10/282:02 pm -
2 stops23h 03m
Deal found 9/5![American Airlines logo]()
$614
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:59 pm -
1 stop12h 15m
Mon 10/263:41 pm -
1 stop22h 32m
Deal found 9/4![United Airlines logo]()
$618
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:40 pm -
2 stops22h 32m
Sun 12/1311:35 am -
2 stops25h 05m
Deal found 9/3![United Airlines logo]()
$623
Best flights from Portland to Panama CityDiscover carefully curated flight deals from Portland to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Portland to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:26 pm -
2 stops16h 19m
Thu 11/54:41 pm -
2 stops28h 43m
Deal found 9/5![United Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:15 pm -
2 stops18h 57m
Mon 12/1411:35 am -
2 stops14h 07m
Deal found 9/6![United Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:40 pm -
2 stops22h 32m
Mon 12/1411:35 am -
1 stop14h 33m
Deal found 9/4![United Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:26 pm -
2 stops21h 12m
Sat 11/214:41 pm -
2 stops28h 43m
Deal found 9/3![United Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/284:05 pm -
2 stops22h 07m
Fri 2/58:55 am -
1 stop17h 23m
Deal found 9/6![United Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/93:30 pm -
2 stops20h 15m
Sat 1/164:41 pm -
2 stops24h 34m
Deal found 9/4![United Airlines logo]()
$613
Last-minute flights from Portland to Panama CityDiscover last-minute flight deals from Portland to Panama City. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Panama City. Data last updated September 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:59 pm -
1 stop12h 15m
Thu 2/2511:35 am -
1 stop14h 37m
Deal found 9/4![United Airlines logo]()
$595
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:59 pm -
1 stop12h 15m
Fri 2/2611:35 am -
1 stop14h 37m
Deal found 9/4![United Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:59 pm -
1 stop16h 38m
Wed 3/38:55 am -
1 stop17h 17m
Deal found 9/3![United Airlines logo]()
$635
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:59 pm -
1 stop12h 15m
Mon 10/263:41 pm -
1 stop22h 32m
Deal found 9/4![United Airlines logo]()
$618
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:25 pm -
2 stops20h 37m
Wed 10/282:02 pm -
2 stops23h 03m
Deal found 9/5![American Airlines logo]()
$614
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:25 pm -
2 stops20h 37m
Mon 10/262:02 pm -
2 stops23h 03m
Deal found 9/3![American Airlines logo]()
$639
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:59 pm -
1 stop16h 38m
Mon 10/263:41 pm -
2 stops24h 53m
Deal found 9/6![United Airlines logo]()
$644
One-way flights from Portland to Panama CitySearch for one-way flight options from Portland to Panama City. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Portland to Panama City. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/35:15 am -
2 stops11h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$242
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:00 am -
1 stop9h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$272
This BusinessClass deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/51:12 pm -
2 stops23h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![GOL logo]()
$305
This Ovago deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
1 stop9h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Copa Airlines logo]()
$312
This KAYAK deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/46:28 am -
2 stops28h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![GOL logo]()
$318
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/410:54 pm -
1 stop11h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2711:02 pm -
1 stop12h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:38 pm -
3 stops29h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$386
This Booking.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:49 pm -
2 stops14h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:29 pm -
2 stops14h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:45 pm -
2 stops18h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$456
Find flight deals from Portland to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $549 (American Airlines) |
One-way from | $242 (United Airlines) |
Popular in | June |
Cheapest in | May |
Average price | $787 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Portland to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Wed 3/3
5:15 am-7:38 pm
2 stops11h 23m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$242
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Sun 11/29
8:29 pm-2:34 pm
2 stops15h 05m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$272
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Fri 11/27
7:26 pm-2:45 pm
2 stops16h 19m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$272
Quickest round-trip
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Mon 11/23
7:00 am-7:38 pm
1 stop9h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$312
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Thu 3/4
6:28 am-1:40 pm
2 stops28h 12m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$318
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Thu 3/4
10:54 pm-1:40 pm
1 stop11h 46m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$355
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Sun 10/4
2:10 pm-12:58 pm
1 stop20h 48m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$432
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Wed 10/7
6:50 am-6:37 pm
1 stop9h 47m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$432
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Thu 10/8
6:50 am-6:37 pm
1 stop9h 47m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$432
PortlandPanama City
PDX Portland - PTY Panama City Tocumen Intl
PDXPTY
Portland
Mon 11/2
7:26 pm-2:45 pm
2 stops16h 19m
Panama City Tocumen Intl
Thu 11/5
4:41 pm-6:24 pm
2 stops28h 43m
$553
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Portland to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Portland with our price prediction graph.
PDX-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Panama City
How far ahead should I book a flight from Portland to Panama City?
Booking 27 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Portland to Panama City?
Currently, May is the cheapest month in which you can book a flight from Portland to Panama City (average of $566). Flying from Portland to Panama City in June is currently the most expensive (average of $918). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Panama City?
Airfare is below average for this route at the moment.
Portland to Panama City flights typically cost between $571 and $824 in November.The cheapest round-trip price found within the last 5 days was $549 on American Airlines (Nov 2-Nov 5).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 7, 2026.
See what other customers who have flown with Copa Airlines,United Airlines, andAmerican Airlines from Portland to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Comfort
7.4
Entertainment
6.9
Food
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Comfort
7.4
Entertainment
6.9
Food
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Comfort
7.4
Entertainment
6.9
Food
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Comfort
7.4
Entertainment
6.9
Food
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Portland to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Panama City by cabin class
Find flights from Portland to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Panama City flights
Browse other Portland and Panama City flight options. Last updated on September 7, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Portland to Panama City
Discover the top 3 airlines that operate flights from Portland to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$408 | Average$680 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$513 | Average$686 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$623 | Average$854 | FlexibilityNo cancel fee | On-time70% |