$209+ Cheap flights from Mexico City (MEX) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — PTY
Oct 29 — Nov 51
Round-trip
1 adult, Economy
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Find cheap flights from Mexico City to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mexico City Benito Juarez to Panama City Tocumen Intl are usually found in February or January, booked 55 days in advance, depart on a Friday or Monday and return on a Friday
Cheap flight deals from Mexico City to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mexico City to Panama CityExplore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:50 am -
Nonstop3h 56m
Fri 11/272:47 pm -
Nonstop3h 53m
Deal found 9/27![Aeromexico logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:50 am -
Nonstop3h 56m
Sat 11/142:47 pm -
Nonstop3h 53m
Deal found 9/28![Aeromexico logo]()
$350
This Trip.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:50 am -
Nonstop3h 56m
Mon 11/302:47 pm -
Nonstop3h 53m
Deal found 9/27![Aeromexico logo]()
$353
This Trip.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:50 am -
Nonstop3h 56m
Tue 11/242:47 pm -
Nonstop3h 53m
Deal found 9/28![Aeromexico logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:50 am -
Nonstop3h 56m
Wed 12/22:47 pm -
Nonstop3h 53m
Deal found 9/26![Aeromexico logo]()
$357
This Trip.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:50 am -
Nonstop3h 56m
Sun 11/222:47 pm -
Nonstop3h 53m
Deal found 9/24![Aeromexico logo]()
$358
This Trip.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:50 am -
Nonstop3h 56m
Tue 11/32:47 pm -
Nonstop3h 53m
Deal found 9/24![Aeromexico logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:55 am -
Nonstop3h 52m
Sat 11/289:24 am -
Nonstop3h 46m
Deal found 9/25![Copa Airlines logo]()
$361
This Trip.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:50 am -
Nonstop3h 56m
Thu 11/52:47 pm -
Nonstop3h 53m
Deal found 9/27![Aeromexico logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:20 am -
Nonstop3h 41m
Thu 11/59:31 pm -
Nonstop3h 44m
Deal found 9/28![Copa Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:25 am -
Nonstop3h 41m
Tue 11/310:17 pm -
Nonstop3h 43m
Deal found 9/27![Copa Airlines logo]()
$366
Best flights from Mexico City to Panama CityDiscover carefully curated flight deals from Mexico City to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from Mexico City to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:30 pm -
Nonstop3h 44m
Tue 11/37:18 pm -
Nonstop4h 07m
Deal found 9/25![Copa Airlines logo]()
$395
This Avianca deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:55 am -
1 stop11h 05m
Sat 10/103:10 pm -
1 stop8h 50m
Deal found 9/23![Avianca logo]()
$499
This Copa Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:30 pm -
Nonstop3h 44m
Mon 10/194:12 pm -
Nonstop3h 53m
Deal found 9/27![Copa Airlines logo]()
$420
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/109:50 am -
Nonstop3h 48m
Sat 10/179:29 am -
Nonstop3h 41m
Deal found 9/24![Copa Airlines logo]()
$420
This Copa Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:10 pm -
Nonstop3h 44m
Wed 10/2110:13 pm -
Nonstop3h 47m
Deal found 9/26![Copa Airlines logo]()
$420
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:25 am -
Nonstop3h 46m
Sat 11/284:29 pm -
Nonstop3h 51m
Deal found 9/24![Copa Airlines logo]()
$420
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:20 am -
Nonstop3h 41m
Sun 10/1110:13 pm -
Nonstop3h 47m
Deal found 9/24![Copa Airlines logo]()
$523
Last-minute flights from Mexico City to Panama CityDiscover last-minute flight deals from Mexico City to Panama City. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from Mexico City to Panama City. Data last updated September 29, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:05 am -
Nonstop3h 50m
Thu 10/153:05 pm -
Nonstop3h 55m
Deal found 9/28![Aeromexico logo]()
$379
This Trip.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:05 am -
Nonstop3h 50m
Wed 10/213:05 pm -
Nonstop3h 55m
Deal found 9/25![Aeromexico logo]()
$380
This Avianca deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:30 am -
1 stop7h 40m
Mon 11/25:30 am -
1 stop6h 30m
Deal found 9/28![Avianca logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:25 am -
Nonstop3h 41m
Tue 11/310:17 pm -
Nonstop3h 43m
Deal found 9/27![Copa Airlines logo]()
$366
This Trip.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:50 am -
Nonstop3h 56m
Tue 11/32:47 pm -
Nonstop3h 53m
Deal found 9/27![Aeromexico logo]()
$352
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:30 am -
1 stop7h 40m
Wed 11/45:30 am -
1 stop6h 30m
Deal found 9/24![Avianca logo]()
$369
This Avianca deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:50 pm -
1 stop10h 30m
Tue 11/34:10 pm -
1 stop12h 00m
Deal found 9/28![Avianca logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:20 am -
Nonstop3h 41m
Thu 11/59:31 pm -
Nonstop3h 44m
Deal found 9/28![Copa Airlines logo]()
$365
This Trip.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:50 am -
Nonstop3h 56m
Thu 11/52:47 pm -
Nonstop3h 53m
Deal found 9/27![Aeromexico logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:00 am -
Nonstop3h 41m
Fri 11/610:17 pm -
Nonstop3h 43m
Deal found 9/27![Copa Airlines logo]()
$374
One-way flights from Mexico City to Panama CitySearch for one-way flight options from Mexico City to Panama City. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
Search for one-way flight options from Mexico City to Panama City. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:05 am -
Nonstop3h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Aeromexico logo]()
$209
This Super.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:10 pm -
Nonstop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Copa Airlines logo]()
$216
This Aeromexico deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:50 am -
Nonstop3h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Aeromexico logo]()
$220
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:55 am -
Nonstop3h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Copa Airlines logo]()
$229
This Cheapflightsfares deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:50 am -
Nonstop3h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Aeromexico logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:50 am -
Nonstop3h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Aeromexico logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/138:50 am -
Nonstop3h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Aeromexico logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:50 am -
Nonstop3h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Aeromexico logo]()
$247
This Copa Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:20 am -
Nonstop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Copa Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/283:25 am -
Nonstop3h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Copa Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:30 pm -
Nonstop3h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Copa Airlines logo]()
$273
Find flight deals from Mexico City to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $349 (Kiwi.com) |
One-way from | $209 (Cheapflightsfares) |
Popular in | July |
Cheapest in | February |
Average price | $429 |
Good round-trip deal | $375 or less |
Good one-way deal | $272 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Fri 10/16
5:50 am-10:41 am
Nonstop3h 51m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$219
Quickest round-trip
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Wed 10/21
2:10 am-6:51 am
Nonstop3h 41m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$219
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Sat 10/31
1:10 pm-5:54 pm
Nonstop3h 44m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$219
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Tue 10/27
3:25 am-8:06 am
Nonstop3h 41m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$219
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Thu 10/15
1:10 pm-5:54 pm
Nonstop3h 44m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$219
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Wed 11/11
5:55 am-10:47 am
Nonstop3h 52m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$229
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Sun 12/13
8:50 am-1:46 pm
Nonstop3h 56m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$245
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Mon 11/23
1:10 pm-5:59 pm
Nonstop3h 49m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$253
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Tue 11/24
1:20 am-6:04 am
Nonstop3h 44m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$253
Mexico CityPanama City
MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl
MEXPTY
Mexico City Benito Juarez
Mon 12/21
3:30 pm-8:20 pm
Nonstop3h 50m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$290
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Mexico City to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Mexico City-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Mexico City-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Mexico City to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
MEX-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mexico City to Panama City
Prices
Airlines
Delays
How far ahead should I book a flight from Mexico City to Panama City?
To ensure you get the cheapest price possible for a flight from Mexico City to Panama City, you should look to book at least 54 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Mexico City to Panama City?
Currently, February is the cheapest month in which you can book a flight from Mexico City to Panama City (average of $360). Flying from Mexico City to Panama City in July is currently the most expensive (average of $445). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MEX to PTY?
Find hourly flight availability from Mexico City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 29, 2026.
One of the essential ways to save on airfare from Mexico City to Panama City is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 14% on airfare.
What is the cheapest day to fly from Mexico City to Panama City?
Use this chart to determine the cheapest time to fly round-trip from Mexico City to Panama City. Price data was last updated on September 19, 2026.
Travelers seeking maximum savings on their Mexico City to Panama City flight should consider departing on Monday evenings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
How often are flights from Mexico City to Panama City delayed?
About 4% of weekly flights between Mexico City and Panama City have experienced delays in the past year, with the average delay time being 117 minutes.
What is the most punctual flight time for Mexico City to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Mexico City to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 4% of flights being delayed.
The best insider tips for Mexico City to Panama City flights
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Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 29, 2026.
Peruse reviews from past customers who have flown with Copa Airlines,Aeromexico, andAvianca from Mexico City to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Comfort
7.4
Food
6.9
Crew
8.1
Boarding
7.8
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Comfort
7.4
Food
6.9
Crew
8.1
Boarding
7.8
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Comfort
7.4
Food
6.9
Crew
8.1
Boarding
7.8
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Comfort
7.4
Food
6.9
Crew
8.1
Boarding
7.8
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
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Top 3 airlines flying from Mexico City to Panama City
Discover the top 3 airlines that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$212 | Average$439 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$226 | Average$380 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$337 | Average$409 | FlexibilityNo cancel fee | On-time71% |