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Panama City

$226+ Cheap flights from Manchester, NH (MHT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — PTY
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Manchester to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$522
(United Airlines)

One-way from

$226
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$530
Provider with most accurate pricing for Manchester-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Manchester-Panama City Tocumen Intl flights.
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From Manchester to Panama City Tocumen Intl
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One-way flight from Manchester to Panama City Tocumen Intl
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Highest demand for flights based on searches. 4% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Manchester to Panama City

Cheapest flights from Manchester to Panama City
Explore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/159:30 amMHT - PTY
2 stops29h 15mUnited Airlines
Wed 11/198:55 amPTY - MHT
2 stops14h 49mUnited Airlines
Deal found 10/28$522
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:20 pmMHT - PTY
2 stops20h 29mAmerican Airlines
Fri 11/212:43 pmPTY - MHT
2 stops24h 53mAmerican Airlines
Deal found 10/27$540
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:55 pmMHT - PTY
2 stops21h 52mAmerican Airlines
Fri 12/194:55 pmPTY - MHT
2 stops18h 16mAmerican Airlines
Deal found 10/28$572
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/99:30 amMHT - PTY
2 stops29h 15mUnited Airlines
Thu 11/134:41 pmPTY - MHT
2 stops31h 03mUnited Airlines
Deal found 10/26$583
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/189:30 amMHT - PTY
2 stops29h 15mUnited Airlines
Fri 11/214:41 pmPTY - MHT
2 stops31h 03mUnited Airlines
Deal found 10/27$707
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:40 pmMHT - PTY
2 stops23h 14mAmerican Airlines
Mon 1/124:50 pmPTY - MHT
2 stops23h 41mAmerican Airlines
Deal found 10/28$1,077
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:59 amMHT - PTY
2 stops22h 23mMultiple Airlines
Fri 12/197:10 pmPTY - MHT
1 stop23h 46mMultiple Airlines
Deal found 10/28$1,539
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:59 pmMHT - PTY
1 stop25h 47mMultiple Airlines
Thu 12/1812:03 pmPTY - MHT
2 stops21h 16mMultiple Airlines
Deal found 10/27$1,540

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

Fly from

Manchester

Fly to

Panama City

Route

Depart

Return

Price

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Thu 12/11

3:55 pm-1:47 pm

2 stops21h 52m

Panama City Tocumen Intl

Thu 12/18

2:53 pm-11:11 am

2 stops20h 18m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 11/15

9:30 am-2:45 pm

2 stops29h 15m

Panama City Tocumen Intl

Wed 11/19

8:55 am-11:44 pm

2 stops14h 49m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 2/13

7:28 pm-5:07 pm

2 stops21h 39m

Panama City Tocumen Intl

Sun 2/22

4:41 pm-6:53 pm

2 stops26h 12m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 12/12

3:55 pm-1:47 pm

2 stops21h 52m

Panama City Tocumen Intl

Fri 12/19

4:55 pm-11:11 am

2 stops18h 16m

$572

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sun 11/9

9:30 am-2:45 pm

2 stops29h 15m

Panama City Tocumen Intl

Thu 11/13

4:41 pm-11:44 pm

2 stops31h 03m

$583

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Tue 11/18

4:05 pm-1:49 pm

2 stops21h 44m

Panama City Tocumen Intl

Fri 11/21

2:43 pm-4:49 pm

2 stops26h 06m

$584

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Tue 11/18

9:30 am-2:45 pm

2 stops29h 15m

Panama City Tocumen Intl

Fri 11/21

4:41 pm-11:44 pm

2 stops31h 03m

$707

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 12/19

4:40 pm-3:54 pm

2 stops23h 14m

Panama City Tocumen Intl

Mon 1/12

4:50 pm-4:31 pm

2 stops23h 41m

$1,077

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 12/12

9:59 am-8:22 am

2 stops22h 23m

Panama City Tocumen Intl

Fri 12/19

7:10 pm-6:56 pm

1 stop23h 46m

$1,539

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 3/23

5:05 pm-2:20 pm

2 stops22h 15m

$226

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 11 results
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Compare providers for flights from Manchester to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Panama City in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Manchester, New Hampshire-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama City

What is the cheapest month to book a flight from Manchester, New Hampshire to Panama City?

Currently, September is the cheapest month in which you can book a flight from Manchester, New Hampshire to Panama City (average of $402). Flying from Manchester, New Hampshire to Panama City in March is currently the most expensive (average of $485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Panama City?

    There are many flights that can get you from Manchester, New Hampshire to Panama City in 21h 52m. Fly via American Airlines or United Airlines to get the fastest option. The distance from Manchester, New Hampshire to Panama City is about 2386 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Manchester to Panama City that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.

  • Can I find deals for business class flights from Manchester to Panama City?

    Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Manchester, New Hampshire to Panama City (average of $402). Flying from Manchester, New Hampshire to Panama City in March is currently the most expensive (average of $485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to Panama City

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