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Panama City

$522+ Cheap flights from Manchester, NH (MHT) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Manchester to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$522
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$529
From Manchester to Panama City Tocumen Intl
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Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Manchester to Panama City

Cheapest flights from Manchester to Panama City
Explore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:48 pmMHT - PTY
2 stops21h 43mAmerican Airlines
Thu 9/253:31 pmPTY - MHT
2 stops23h 17mAmerican Airlines
Deal found 9/11$522
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:26 pmMHT - PTY
2 stops20h 29mAmerican Airlines
Thu 9/253:31 pmPTY - MHT
2 stops30h 31mAmerican Airlines
Deal found 9/9$678
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/269:30 amMHT - PTY
2 stops29h 15mUnited Airlines
Sun 11/24:41 pmPTY - MHT
2 stops31h 03mUnited Airlines
Deal found 9/11$764

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

Fly from

Manchester

Fly to

Panama City

Route

Depart

Return

Price

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Wed 1/28

7:26 pm-7:38 pm

2 stops24h 12m

Panama City Tocumen Intl

Mon 2/9

4:41 pm-6:51 pm

2 stops26h 10m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 11/28

4:04 pm-1:38 pm

2 stops21h 34m

Panama City Tocumen Intl

Tue 1/27

2:45 pm-11:53 am

2 stops21h 08m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 1/26

7:26 pm-5:07 pm

2 stops21h 41m

Panama City Tocumen Intl

Thu 2/12

10:00 am-11:59 pm

2 stops13h 59m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Wed 10/29

2:27 pm-1:45 pm

2 stops24h 18m

Panama City Tocumen Intl

Thu 11/6

8:55 am-11:44 pm

2 stops14h 49m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Thu 1/29

7:26 pm-5:07 pm

2 stops21h 41m

Panama City Tocumen Intl

Wed 2/11

11:35 am-11:28 am

2 stops23h 53m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Wed 1/28

7:26 pm-5:07 pm

2 stops21h 41m

Panama City Tocumen Intl

Wed 2/11

11:35 am-11:28 am

2 stops23h 53m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sun 1/25

7:26 pm-1:55 pm

2 stops18h 29m

Panama City Tocumen Intl

Wed 2/11

11:35 am-11:28 am

2 stops23h 53m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 1/30

7:26 pm-5:07 pm

2 stops21h 41m

Panama City Tocumen Intl

Fri 2/13

11:35 am-11:59 pm

2 stops12h 24m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 1/26

7:26 pm-7:38 pm

2 stops24h 12m

Panama City Tocumen Intl

Wed 2/11

11:35 am-11:28 am

2 stops23h 53m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 1/24

7:26 pm-1:55 pm

2 stops18h 29m

Panama City Tocumen Intl

Wed 2/11

11:35 am-11:28 am

2 stops23h 53m

$522

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 12 results
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Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama City

What is the cheapest month to book a flight from Manchester, New Hampshire to Panama City?

Currently, October is the cheapest month in which you can book a flight from Manchester, New Hampshire to Panama City (average of $478). Flying from Manchester, New Hampshire to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Panama City?

    There are many flights that can get you from Manchester, New Hampshire to Panama City in 24h 12m. Fly via United Airlines to get the fastest option. The distance from Manchester, New Hampshire to Panama City is about 2386 mi.

  • Can I find deals for flights from Manchester to Panama City that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.

  • Can I find deals for business class flights from Manchester to Panama City?

    Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Manchester, New Hampshire to Panama City (average of $478). Flying from Manchester, New Hampshire to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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