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Panama City

$397+ Cheap flights from Louisville (SDF) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PTY
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Louisville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$423
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$482
From Louisville Intl to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($62 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Louisville to Panama City

Cheapest flights from Louisville to Panama City
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Avianca Connect deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/268:23 amSDF - PTY
2 stops13h 47mMultiple Airlines
Sun 9/283:20 amPTY - SDF
2 stops17h 44mMultiple Airlines
Deal found 8/14$397
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:00 amSDF - PTY
1 stop7h 56mDelta
Thu 10/232:21 pmPTY - SDF
1 stop7h 13mDelta
Deal found 8/14$423
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:20 pmSDF - PTY
2 stops24h 17mUnited Airlines
Thu 10/239:45 amPTY - SDF
1 stop9h 42mUnited Airlines
Deal found 8/14$428
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:09 amSDF - PTY
1 stop6h 47mDelta
Wed 10/222:21 pmPTY - SDF
1 stop8h 38mDelta
Deal found 8/14$430
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/195:02 pmSDF - PTY
2 stops22h 01mAmerican Airlines
Wed 10/223:15 pmPTY - SDF
2 stops22h 51mAmerican Airlines
Deal found 8/14$435
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/279:40 amSDF - PTY
1 stop9h 57mUnited Airlines
Sat 10/49:45 amPTY - SDF
1 stop10h 15mUnited Airlines
Deal found 8/13$439
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:31 pmSDF - PTY
2 stops18h 05mAmerican Airlines
Sun 11/232:43 pmPTY - SDF
2 stops20h 46mAmerican Airlines
Deal found 8/14$440
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:15 amSDF - PTY
1 stop12h 22mUnited Airlines
Fri 9/2610:00 amPTY - SDF
1 stop26h 10mUnited Airlines
Deal found 8/13$441
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:44 pmSDF - PTY
2 stops20h 47mAmerican Airlines
Mon 9/293:31 pmPTY - SDF
2 stops22h 05mAmerican Airlines
Deal found 8/14$446
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/219:40 amSDF - PTY
1 stop9h 57mUnited Airlines
Sun 8/243:30 pmPTY - SDF
2 stops17h 32mUnited Airlines
Deal found 8/14$448

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Louisville

Fly to

Panama City

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 9/26

8:23 am-9:10 pm

2 stops13h 47m

Panama City Tocumen Intl

Sun 9/28

3:20 am-10:04 pm

2 stops17h 44m

$397

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 10/23

9:40 am-6:37 pm

1 stop9h 57m

Panama City Tocumen Intl

Mon 10/27

7:55 am-9:57 pm

1 stop13h 02m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 10/20

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Thu 10/23

2:21 pm-10:34 pm

1 stop7h 13m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 11/6

9:15 am-7:38 pm

1 stop10h 23m

Panama City Tocumen Intl

Mon 11/10

8:55 am-9:57 pm

1 stop13h 02m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 11/4

7:10 am-7:38 pm

1 stop12h 28m

Panama City Tocumen Intl

Tue 11/18

8:55 am-9:57 pm

1 stop13h 02m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 11/4

11:19 am-1:36 pm

2 stops26h 17m

Panama City Tocumen Intl

Tue 11/18

2:43 pm-10:45 am

2 stops20h 02m

$428

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 10/20

5:48 pm-2:14 pm

2 stops21h 26m

Panama City Tocumen Intl

Thu 10/23

9:45 am-8:27 pm

1 stop9h 42m

$428

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Louisville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama City

What is the cheapest month to book a flight from Louisville to Panama City?

Currently, October is the cheapest month in which you can book a flight from Louisville to Panama City (average of $478). Flying from Louisville to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to PTY?

Find hourly flight availability from Louisville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

One of the essential ways to save on airfare from Louisville to Panama City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 23% on airfare.

How much does it cost to fly round-trip from Louisville to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 14, 2025.
Read through reviews of airlines operating flights from Louisville to Panama City, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Louisville to Panama City round-trip?

    According to our current data, American Airlines ($338), United Airlines ($351), and Delta ($382) offers the cheapest pricing from Louisville to Panama City. American Airlines is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Louisville to Panama City that include hotel bookings?

    Yes. In addition to deals on Louisville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama City.

  • Can I find deals for business class flights from Louisville to Panama City?

    Yes. Cheapflights offers flight deals from Louisville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Louisville to Panama City (average of $478). Flying from Louisville to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisville to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisville to Panama City

Discover the top 3 airlines that operate flights from Louisville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$338Average$582FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$351Average$512FlexibilityNo cancel feeOn-time69%
DeltaCheapest$382Average$504FlexibilityNo cancel feeOn-timeN/A

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