HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$190+ Cheap flights from Louisville (SDF) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PTY
Mar 3 — Mar 101
Tue 3/3
Tue 3/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Louisville to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Louisville to Panama City

Cheapest flights from Louisville to Panama City
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 1, 2026.

This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:35 am
SDF
-
PTY
2 stops11h 32m
United Airlines
Wed 2/49:55 am
PTY
-
SDF
1 stop12h 04m
United Airlines
Deal found 1/30$436
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:55 pm
SDF
-
PTY
2 stops15h 09m
United Airlines
Sat 4/2510:00 am
PTY
-
SDF
2 stops12h 46m
United Airlines
Deal found 1/30$443
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:15 am
SDF
-
PTY
1 stop10h 23m
United Airlines
Wed 3/48:55 am
PTY
-
SDF
1 stop12h 51m
United Airlines
Deal found 1/29$445
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:49 pm
SDF
-
PTY
2 stops21h 51m
American Airlines
Wed 3/42:40 pm
PTY
-
SDF
2 stops18h 22m
American Airlines
Deal found 1/30$454
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:58 pm
SDF
-
PTY
2 stops15h 12m
United Airlines
Wed 4/17:55 am
PTY
-
SDF
1 stop13h 04m
United Airlines
Deal found 1/30$456
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/249:00 am
SDF
-
PTY
2 stops10h 38m
United Airlines
Fri 2/274:41 pm
PTY
-
SDF
2 stops20h 42m
United Airlines
Deal found 1/29$458
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/16:12 pm
SDF
-
PTY
2 stops22h 55m
United Airlines
Sun 2/84:41 pm
PTY
-
SDF
2 stops20h 43m
United Airlines
Deal found 1/31$469
This KAYAK deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:43 pm
SDF
-
PTY
2 stops21h 31m
Copa Airlines
Fri 4/103:30 pm
PTY
-
SDF
2 stops20h 47m
Copa Airlines
Deal found 1/31$475

Find flight deals from Louisville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$443
(United Airlines)

One-way from

$190
(Delta)

Popular in

December

Cheapest in

September

Average price

$475
Provider with most accurate pricing for Louisville Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Panama City Tocumen Intl flights.
Search Deals
From Louisville Intl to Panama City Tocumen Intl
Search Deals
One-way flight from Louisville Intl to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($43 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 1, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Louisville

Fly to

Panama City

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 4/21

1:55 pm-4:04 am

2 stops15h 09m

Panama City Tocumen Intl

Sat 4/25

10:00 am-11:46 pm

2 stops12h 46m

$443

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 3/2

6:00 am-2:45 pm

1 stop8h 45m

Panama City Tocumen Intl

Wed 3/4

8:55 am-9:46 pm

1 stop12h 51m

$445

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 2/23

8:02 pm-1:40 pm

2 stops17h 38m

Panama City Tocumen Intl

Wed 3/4

2:40 pm-11:59 pm

1 stop9h 19m

$449

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 2/23

5:35 am-7:38 pm

2 stops14h 03m

Panama City Tocumen Intl

Wed 3/4

8:55 am-9:46 pm

1 stop12h 51m

$449

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 3/2

3:49 pm-1:40 pm

2 stops21h 51m

Panama City Tocumen Intl

Wed 3/4

2:40 pm-9:02 am

2 stops18h 22m

$454

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sun 3/1

7:51 pm-1:50 pm

1 stop17h 59m

$190

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 3/3

5:35 am-7:38 pm

2 stops14h 03m

$190

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 2/26

5:35 am-8:02 pm

2 stops14h 27m

$190

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 3/2

7:00 am-1:50 pm

1 stop6h 50m

$190

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 3/3

5:33 am-1:50 pm

1 stop8h 17m

$190

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Showing 1-10 of 13 results
1
2

Compare providers for flights from Louisville to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Panama City in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama City

What is the cheapest month to book a flight from Louisville to Panama City?

Currently, May is the cheapest month in which you can book a flight from Louisville to Panama City (average of $237). Flying from Louisville to Panama City in November is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 1, 2026.
Read through reviews of airlines operating flights from Louisville to Panama City, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,130 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,130 reviews
Delta
7.9
Good
8,130 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,219 reviews
Delta
7.9
Good
8,130 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,213 reviews
Delta
7.9
Good
8,130 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Panama City?

    Airlines like United Airlines fly from Louisville to Panama City in about 15h 09m. The time it takes to get you to your destination can typically vary by up to . There are 2048 mi between Louisville and Panama City.

  • What are the cheapest airlines flying from Louisville to Panama City round-trip?

    According to our current data, United Airlines ($381), American Airlines ($410), and Delta ($423) offers the cheapest pricing from Louisville to Panama City. United Airlines is currently priced 24% below the average price you’ll pay for this route.

  • Can I find deals for flights from Louisville to Panama City that include hotel bookings?

    Yes. In addition to deals on Louisville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama City.

  • Can I find deals for business class flights from Louisville to Panama City?

    Yes. Cheapflights offers flight deals from Louisville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Panama City?

    Currently, May is the cheapest month in which you can book a flight from Louisville to Panama City (average of $237). Flying from Louisville to Panama City in November is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Louisville to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Panama City flights
Cincinnati to Panama City flights
Blountville to Panama City flights
Evansville to Panama City flights
Lexington to Panama City flights
Knoxville to Panama City flights

Top 3 airlines flying from Louisville to Panama City

Discover the top 3 airlines that operate flights from Louisville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$381Average$481FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$410Average$593FlexibilityNo cancel feeOn-time71%
DeltaCheapest$430Average$573FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.