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Panama City

$292+ Cheap flights from Louisville (SDF) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PTY
Aug 17 — Aug 241
Mon 8/17
Mon 8/24
1 adult, Economy
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Cheap flight deals from Louisville to Panama City

Cheapest flights from Louisville to Panama City
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.

This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:15 am
SDF
-
PTY
1 stop14h 16m
United Airlines
Sat 10/109:45 am
PTY
-
SDF
1 stop9h 28m
United Airlines
Deal found 7/15$649
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:15 am
SDF
-
PTY
1 stop14h 16m
United Airlines
Fri 9/410:55 pm
PTY
-
SDF
1 stop12h 27m
United Airlines
Deal found 7/14$651
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:15 am
SDF
-
PTY
1 stop14h 16m
United Airlines
Fri 10/93:30 pm
PTY
-
SDF
2 stops20h 45m
United Airlines
Deal found 7/15$653
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:23 am
SDF
-
PTY
2 stops18h 41m
United Airlines
Fri 8/213:30 pm
PTY
-
SDF
2 stops24h 08m
United Airlines
Deal found 7/17$657
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:49 pm
SDF
-
PTY
2 stops20h 03m
American Airlines
Sun 10/251:52 pm
PTY
-
SDF
2 stops21h 16m
American Airlines
Deal found 7/14$658
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:15 am
SDF
-
PTY
2 stops12h 22m
United Airlines
Sat 8/153:30 pm
PTY
-
SDF
2 stops17h 08m
United Airlines
Deal found 7/14$660
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:14 pm
SDF
-
PTY
1 stop31h 17m
United Airlines
Tue 9/810:00 am
PTY
-
SDF
2 stops22h 37m
United Airlines
Deal found 7/16$665
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:43 am
SDF
-
PTY
1 stop18h 21m
United Airlines
Tue 9/89:45 am
PTY
-
SDF
1 stop9h 24m
United Airlines
Deal found 7/18$667
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:35 pm
SDF
-
PTY
1 stop23h 39m
United Airlines
Sat 8/293:30 pm
PTY
-
SDF
2 stops20h 41m
United Airlines
Deal found 7/15$669
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:15 am
SDF
-
PTY
2 stops14h 22m
United Airlines
Sun 8/163:30 pm
PTY
-
SDF
2 stops17h 08m
United Airlines
Deal found 7/18$673

Find flight deals from Louisville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$629
(United Airlines)

One-way from

$292
(Delta)

Popular in

July

Cheapest in

February

Average price

$723
Provider with most accurate pricing for Louisville Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Panama City Tocumen Intl flights.
Search Deals
From Louisville Intl to Panama City Tocumen Intl
Search Deals
One-way flight from Louisville Intl to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 9/10

9:45 am-6:37 pm

1 stop9h 52m

Panama City Tocumen Intl

Mon 9/14

10:00 am-10:15 pm

1 stop11h 15m

$649

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 9/3

6:15 am-7:31 pm

1 stop14h 16m

Panama City Tocumen Intl

Tue 9/8

10:00 am-10:15 pm

1 stop11h 15m

$649

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sun 10/4

6:15 am-7:31 pm

1 stop14h 16m

Panama City Tocumen Intl

Thu 10/8

10:00 am-10:10 pm

1 stop11h 10m

$649

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 8/28

6:15 am-7:31 pm

1 stop14h 16m

Panama City Tocumen Intl

Fri 9/4

10:55 pm-12:22 pm

1 stop12h 27m

$651

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 9/10

7:27 pm-12:16 pm

2 stops17h 49m

Panama City Tocumen Intl

Mon 9/14

1:16 pm-10:40 am

2 stops20h 24m

$653

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 10/17

5:15 am-7:31 pm

2 stops15h 16m

Panama City Tocumen Intl

Wed 10/21

9:45 am-11:49 pm

1 stop13h 04m

$653

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 1/11

5:30 am-5:12 pm

2 stops11h 42m

Panama City Tocumen Intl

Sun 1/17

4:41 pm-1:00 pm

2 stops20h 19m

$653

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 1/5

8:45 am-8:02 pm

1 stop11h 17m

Panama City Tocumen Intl

Tue 1/12

4:41 pm-9:45 am

2 stops17h 04m

$653

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sun 1/10

7:05 am-7:38 pm

1 stop12h 33m

Panama City Tocumen Intl

Sat 1/16

11:35 am-9:45 am

2 stops22h 10m

$653

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 8/14

10:23 am-4:04 am

2 stops18h 41m

Panama City Tocumen Intl

Fri 8/21

3:30 pm-4:38 pm

2 stops24h 08m

$657

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/16

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Louisville to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Panama City in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama City

What is the cheapest month to book a flight from Louisville to Panama City?

Currently, February is the cheapest month in which you can book a flight from Louisville to Panama City (average of $430). Flying from Louisville to Panama City in July is currently the most expensive (average of $723). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Louisville to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 18, 2026.
Read through reviews of airlines operating flights from Louisville to Panama City, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,478 reviews

Comfort

7.8

Overall

7.8

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,478 reviews
Delta
7.8
Good
8,478 reviews

Comfort

7.8

Overall

7.8

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
10,006 reviews
Delta
7.8
Good
8,478 reviews

Comfort

7.8

Overall

7.8

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,828 reviews
Delta
7.8
Good
8,478 reviews

Comfort

7.8

Overall

7.8

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Panama City?

    Airlines like United Airlines fly from Louisville to Panama City in about 14h 16m. The time it takes to get you to your destination can typically vary by up to . There are 2048 mi between Louisville and Panama City.

  • What are the cheapest airlines flying from Louisville to Panama City round-trip?

    According to our current data, United Airlines ($430), American Airlines ($434), and Delta ($558) offers the cheapest pricing from Louisville to Panama City. United Airlines is currently priced 26% below the average price you’ll pay for this route.

  • Can I find deals for flights from Louisville to Panama City that include hotel bookings?

    Yes. In addition to deals on Louisville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama City.

  • Can I find deals for business class flights from Louisville to Panama City?

    Yes. Cheapflights offers flight deals from Louisville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Panama City?

    Currently, February is the cheapest month in which you can book a flight from Louisville to Panama City (average of $430). Flying from Louisville to Panama City in July is currently the most expensive (average of $723). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Louisville to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Panama City flights
Cincinnati to Panama City flights
Knoxville to Panama City flights
Evansville to Panama City flights

Top 3 airlines flying from Louisville to Panama City

Discover the top 3 airlines that operate flights from Louisville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$430Average$558FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$434Average$749FlexibilityNo cancel feeOn-time71%
DeltaCheapest$558Average$632FlexibilityNo cancel feeOn-timeN/A

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