Arrive at GUA 2 to 3 hours before departure due to unpredictable security lines, especially for early or late flights.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $200 (Copa Airlines) |
One-way from | $90 (Copa Airlines) |
Popular in | December |
Cheapest in | May |
Average price | $278 |
Good round-trip deal | $318 or less |
Good one-way deal | $163 or less |
Fly from
Fly to
Route
Depart
Return
Price
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Mon 2/2
4:24 am-7:50 am
Nonstop2h 26m
Panama City Tocumen Intl
Tue 2/10
8:11 am-9:34 am
Nonstop2h 23m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Thu 2/12
4:24 am-7:50 am
Nonstop2h 26m
Panama City Tocumen Intl
Sat 2/21
7:31 am-8:55 am
Nonstop2h 24m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Fri 2/13
4:24 am-7:50 am
Nonstop2h 26m
Panama City Tocumen Intl
Wed 2/18
6:34 pm-9:40 pm
1 stop4h 06m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Tue 1/6
4:27 pm-7:51 pm
Nonstop2h 24m
Panama City Tocumen Intl
Sat 1/10
7:31 am-8:55 am
Nonstop2h 24m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Fri 2/13
4:24 am-7:50 am
Nonstop2h 26m
Panama City Tocumen Intl
Sat 2/21
7:31 am-8:55 am
Nonstop2h 24m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Fri 12/12
6:24 am-8:18 pm
1 stop12h 54m
Panama City Tocumen Intl
Wed 12/24
9:45 pm-11:11 pm
Nonstop2h 26m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Sun 2/8
4:24 am-7:50 am
Nonstop2h 26m
Panama City Tocumen Intl
Tue 2/17
9:34 am-9:40 pm
1 stop13h 06m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Tue 12/23
4:28 pm-7:55 pm
Nonstop2h 27m
Panama City Tocumen Intl
Fri 1/2
7:31 am-8:55 am
Nonstop2h 24m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Tue 12/9
4:28 pm-7:55 pm
Nonstop2h 27m
Guatemala CityPanama City
GUA - PTY
GUAPTY
Guatemala City La Aurora
Sat 1/17
4:27 pm-7:51 pm
Nonstop2h 24m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars |
The best time to book flights from Guatemala City to Panama City is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Currently, April is the cheapest month in which you can book a flight from Guatemala City to Panama City (average of $95). Flying from Guatemala City to Panama City in January is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
One of the essential ways to save on airfare from Guatemala City to Panama City is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 68% on airfare.
Travelers seeking maximum savings on their Guatemala City to Panama City flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
About 5% of weekly flights between Guatemala City and Panama City have experienced delays in the past year, with the average delay time being 115 minutes.
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Tuesday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 5% of flights being delayed.
Entertainment
Boarding
Comfort
Food
Crew
Overall
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Entertainment
Boarding
Comfort
Food
Crew
Overall
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Entertainment
Boarding
Comfort
Food
Crew
Overall
Reviews
Juan Pablo,Sep 2025
MEX - PTY
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$190 | Average$295 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$199 | Average$280 | FlexibilityNo cancel fee | On-time70% |