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Panama City

$191+ Cheap flights from Durham, NC to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
ene. 15 — ene. 221
jue. 1/15
jue. 1/22
1 adult, Economy
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Cheapflights Tip: The best prices from Durham to Panama City Tocumen Intl are usually found in October or September, booked 61 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Durham to Panama City

Cheapest flights from Durham to Panama City
Explore the most affordable flight options available from Durham to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:10 amRDU - PTY
1 stop10h 57mUnited Airlines
mié. 1/2110:00 amPTY - RDU
1 stop11h 05mUnited Airlines
Deal found 12/14$509
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/308:17 pmRDU - PTY
2 stops19h 37mAmerican Airlines
mié. 1/212:27 pmPTY - RDU
2 stops19h 28mAmerican Airlines
Deal found 12/14$513
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/298:17 pmRDU - PTY
2 stops19h 37mAmerican Airlines
lun. 1/194:50 pmPTY - RDU
2 stops19h 31mAmerican Airlines
Deal found 12/14$543
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:10 amRDU - PTY
1 stop13h 28mUnited Airlines
lun. 1/194:41 pmPTY - RDU
1 stop29h 49mUnited Airlines
Deal found 12/14$558
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/246:31 amRDU - PTY
2 stops13h 07mUnited Airlines
mié. 12/314:41 pmPTY - RDU
1 stop18h 40mUnited Airlines
Deal found 12/16$626
This Copa Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/293:11 pmRDU - PTY
Nonstop4h 35mCopa Airlines
lun. 1/198:57 amPTY - RDU
Nonstop4h 18mCopa Airlines
Deal found 12/14$634
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/244:16 pmRDU - PTY
2 stops21h 37mAmerican Airlines
mié. 12/314:55 pmPTY - RDU
1 stop7h 38mAmerican Airlines
Deal found 12/15$675
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/208:48 pmRDU - PTY
2 stops17h 05mAmerican Airlines
vie. 1/162:27 pmPTY - RDU
2 stops18h 54mAmerican Airlines
Deal found 12/16$760

Find flight deals from Durham to Panama City

Keep the following information in mind while searching for Durham to Panama City flight deals. Data was last updated diciembre 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$441
(Copa Airlines)

One-way from

$191
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$809
Provider with most accurate pricing for Raleigh-Durham-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City Tocumen Intl flights.
Search Deals
From Durham to Panama City Tocumen Intl
Search Deals
One-way flight from Durham to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from Durham to Panama City that are best for you.

Fly from

Durham

Fly to

Panama City

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

vie. 3/13

4:14 pm-7:46 pm

Nonstop4h 32m

Panama City Tocumen Intl

vie. 3/20

8:57 am-2:23 pm

Nonstop4h 26m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

mié. 2/4

3:12 pm-7:46 pm

Nonstop4h 34m

Panama City Tocumen Intl

mié. 2/18

8:57 am-1:14 pm

Nonstop4h 17m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

vie. 2/20

3:12 pm-7:46 pm

Nonstop4h 34m

Panama City Tocumen Intl

lun. 2/23

8:57 am-1:14 pm

Nonstop4h 17m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

vie. 1/30

3:09 pm-7:46 pm

Nonstop4h 37m

Panama City Tocumen Intl

dom. 2/8

8:57 am-1:14 pm

Nonstop4h 17m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

lun. 1/19

3:09 pm-7:46 pm

Nonstop4h 37m

Panama City Tocumen Intl

lun. 1/26

8:57 am-1:15 pm

Nonstop4h 18m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

lun. 4/20

6:30 am-2:14 pm

1 stop8h 44m

Panama City Tocumen Intl

lun. 5/4

9:45 am-9:48 pm

1 stop11h 03m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

lun. 1/26

6:15 am-7:38 pm

1 stop13h 23m

Panama City Tocumen Intl

jue. 1/29

11:35 am-10:38 pm

1 stop11h 03m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

dom. 1/25

6:15 am-2:45 pm

1 stop8h 30m

Panama City Tocumen Intl

mié. 2/4

10:00 am-9:05 pm

1 stop11h 05m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

vie. 1/23

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

vie. 1/30

8:55 am-10:30 pm

1 stop13h 35m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

vie. 1/30

11:18 am-8:02 pm

1 stop8h 44m

Panama City Tocumen Intl

vie. 2/6

10:00 am-9:05 pm

1 stop11h 05m

$456

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 20 results
1
2

Best time to book a flight from Durham to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Panama City

How far ahead should I book a flight from Durham to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Panama City. Price data was last updated on December 12, 2025.

Booking 61 days in advance of your planned departure date is, on average, the best time to get cheap flights from Durham to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Durham to Panama City?

Currently, August is the cheapest month in which you can book a flight from Durham to Panama City (average of $234). Flying from Durham to Panama City in December is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to PTY?

Find hourly flight availability from Durham to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

It’s optimal to fly from Durham to Panama City at noon. By choosing this option you can save up to 47% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Durham to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated diciembre 16, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from Durham to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,556 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,094 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Durham?

    If you book a flight to Panama City from Durham, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Durham to Tocumen Intl per day from 4 different airlines.

  • How popular is this Durham to Panama City flight route?

    Flights from Durham to Panama City Tocumen Intl have been viewed 16 times in the past calendar month.

  • How long is the flight from Durham to Panama City?

    A quick flight from Durham to Panama City can take about 4h 34m. Copa Airlines provides one of the quickest options available for as low as $441. The distance between Durham and Panama City is about 1851 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Durham to Panama City?

    While on average a flight from Durham to Panama City is generally $426, our data shows the cheapest flight currently is $139. When looking at the most popular route, (Raleigh-Durham - Panama City Tocumen Intl), you can expect to pay $441 for that flight.

  • Can I find deals for flights from Durham to Panama City that include hotel bookings?

    Yes. In addition to deals on Durham to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Panama City.

  • Can I find deals for business class flights from Durham to Panama City?

    Yes. Cheapflights offers flight deals from Durham to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Panama City?

    Currently, August is the cheapest month in which you can book a flight from Durham to Panama City (average of $234). Flying from Durham to Panama City in December is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Durham to Panama City

Discover the top 4 airlines that operate flights from Durham to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$583FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$352Average$470FlexibilityNo cancel feeOn-time70%
DeltaCheapest$367Average$531FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$513FlexibilityNo cancel feeOn-time69%

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