HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$170+ Cheap flights from Durham, NC to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
Nov 30 — Dec 71
Sun 11/30
Sun 12/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Durham to Panama City Tocumen Intl are usually found in November or October, booked 61 days in advance, depart on a Tuesday or Sunday and return on a Monday

Find flight deals from Durham to Panama City

Cheapest flights from Durham to Panama City
Explore the most affordable flight options available from Durham to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2712:13 pmRDU - PTY
1 stop7h 07mMultiple Airlines
Thu 12/410:25 amPTY - RDU
2 stops13h 47mMultiple Airlines
Deal found 10/28$436
This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:14 pmRDU - PTY
Nonstop4h 32mCopa Airlines
Wed 12/38:57 amPTY - RDU
Nonstop4h 28mCopa Airlines
Deal found 10/27$441
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2712:13 pmRDU - PTY
1 stop8h 24mMultiple Airlines
Wed 12/312:33 pmPTY - RDU
2 stops11h 39mMultiple Airlines
Deal found 10/28$447
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/173:55 pmRDU - PTY
1 stop16h 11mMultiple Airlines
Wed 11/196:34 pmPTY - RDU
1 stop16h 44mMultiple Airlines
Deal found 10/29$450
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:07 amRDU - PTY
1 stop13h 31mUnited Airlines
Thu 12/411:55 pmPTY - RDU
1 stop8h 27mUnited Airlines
Deal found 10/28$456
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:07 pmRDU - PTY
2 stops19h 36mAmerican Airlines
Fri 12/192:53 pmPTY - RDU
1 stop9h 40mAmerican Airlines
Deal found 10/28$460
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:07 pmRDU - PTY
2 stops19h 36mAmerican Airlines
Sun 12/72:50 pmPTY - RDU
2 stops18h 39mAmerican Airlines
Deal found 10/28$465
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:50 pmRDU - PTY
1 stop17h 53mAmerican Airlines
Thu 12/42:50 pmPTY - RDU
2 stops18h 39mAmerican Airlines
Deal found 10/28$470
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:07 amRDU - PTY
1 stop13h 31mUnited Airlines
Wed 12/38:55 amPTY - RDU
1 stop13h 20mUnited Airlines
Deal found 10/28$480
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:31 pmRDU - PTY
2 stops19h 12mAmerican Airlines
Wed 12/34:43 pmPTY - RDU
1 stop7h 16mAmerican Airlines
Deal found 10/28$484

Cheap flight deals from Durham to Panama City

Keep the following information in mind while searching for Durham to Panama City flight deals. Data was last updated October 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$441
(Copa Airlines)

One-way from

$170
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$402
Provider with most accurate pricing for Raleigh-Durham-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City Tocumen Intl flights.
Search Deals
From Durham to Panama City Tocumen Intl
Search Deals
One-way flight from Durham to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
Use the filters below to find and compare flights from Durham to Panama City that are best for you.

Fly from

Durham

Fly to

Panama City

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 2/4

3:12 pm-7:46 pm

Nonstop4h 34m

Panama City Tocumen Intl

Wed 2/18

8:57 am-1:14 pm

Nonstop4h 17m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 11/26

6:07 am-2:45 pm

1 stop8h 38m

Panama City Tocumen Intl

Fri 12/5

11:35 am-10:15 pm

1 stop10h 40m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 3/13

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Thu 3/19

7:55 am-10:36 pm

1 stop13h 41m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 2/8

3:12 pm-7:46 pm

Nonstop4h 34m

Panama City Tocumen Intl

Sun 2/22

8:57 am-1:14 pm

Nonstop4h 17m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sat 11/29

6:04 am-2:45 pm

1 stop8h 41m

Panama City Tocumen Intl

Wed 12/3

10:00 am-8:55 pm

1 stop10h 55m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 3/16

11:20 am-7:02 pm

1 stop8h 42m

Panama City Tocumen Intl

Wed 3/18

10:55 pm-9:16 am

1 stop9h 21m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 2/8

6:15 am-7:38 pm

2 stops13h 23m

Panama City Tocumen Intl

Sun 2/22

8:55 am-10:33 pm

1 stop13h 38m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 2/4

6:15 am-7:38 pm

2 stops13h 23m

Panama City Tocumen Intl

Wed 2/18

11:35 am-10:33 pm

1 stop10h 58m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 3/13

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Fri 3/20

11:35 am-10:36 pm

1 stop10h 01m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 3/15

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Wed 3/18

7:55 am-10:36 pm

1 stop13h 41m

$456

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 17 results
1
2

Best time to book a flight from Durham to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Panama City

How far ahead should I book a flight from Durham to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Panama City. Price data was last updated on October 24, 2025.

Booking 61 days in advance of your planned departure date is, on average, the best time to get cheap flights from Durham to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Durham to Panama City?

Currently, August is the cheapest month in which you can book a flight from Durham to Panama City (average of $234). Flying from Durham to Panama City in December is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to PTY?

Find hourly flight availability from Durham to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 31, 2025.

It’s optimal to fly from Durham to Panama City at noon. By choosing this option you can save up to 44% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 31, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from Durham to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Copa Airlines
7.6
Good
1,561 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,995 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,034 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Durham to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Durham?

    If you book a flight to Panama City from Durham, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Durham to Tocumen Intl per day from 4 different airlines.

  • How popular is this Durham to Panama City flight route?

    Flights from Durham to Panama City Tocumen Intl have been viewed 21 times in the past calendar month.

  • How long is the flight from Durham to Panama City?

    A quick flight from Durham to Panama City can take about 4h 34m. Copa Airlines provides one of the quickest options available for as low as $441. The distance between Durham and Panama City is about 1851 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Durham to Panama City?

    While on average a flight from Durham to Panama City is generally $665, our data shows the cheapest flight currently is $105. When looking at the most popular route, (Raleigh-Durham - Panama City Tocumen Intl), you can expect to pay $441 for that flight.

  • Can I find deals for flights from Durham to Panama City that include hotel bookings?

    Yes. In addition to deals on Durham to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Panama City.

  • Can I find deals for business class flights from Durham to Panama City?

    Yes. Cheapflights offers flight deals from Durham to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Panama City?

    Currently, August is the cheapest month in which you can book a flight from Durham to Panama City (average of $234). Flying from Durham to Panama City in December is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Durham to Panama City

Discover the top 4 airlines that operate flights from Durham to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$584FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$290Average$457FlexibilityNo cancel feeOn-time70%
DeltaCheapest$367Average$542FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$498FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.