HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$193+ Cheap flights from Durham, NC to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Durham to Panama City Tocumen Intl are usually found in October or September, booked 61 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Durham to Panama City

Cheapest flights from Durham to Panama City
Explore the most affordable flight options available from Durham to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Trip.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:18 am
RDU
-
PTY
2 stops17h 47m
Multiple Airlines
Fri 5/13:05 am
PTY
-
RDU
2 stops27h 28m
Multiple Airlines
Deal found 1/28$437
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:08 pm
RDU
-
PTY
3 stops23h 47m
Multiple Airlines
Wed 3/112:55 am
PTY
-
RDU
2 stops14h 49m
Multiple Airlines
Deal found 1/27$454
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:08 am
RDU
-
PTY
1 stop6h 02m
American Airlines
Sun 10/113:35 pm
PTY
-
RDU
1 stop6h 53m
American Airlines
Deal found 1/28$467
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/273:12 pm
RDU
-
PTY
Nonstop4h 34m
Copa Airlines
Fri 3/68:57 am
PTY
-
RDU
Nonstop4h 26m
Copa Airlines
Deal found 1/28$468
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:08 pm
RDU
-
PTY
3 stops23h 47m
Multiple Airlines
Fri 3/133:50 pm
PTY
-
RDU
2 stops24h 39m
Multiple Airlines
Deal found 1/28$469
This Copa Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:21 pm
RDU
-
PTY
Nonstop4h 25m
Copa Airlines
Wed 9/168:57 am
PTY
-
RDU
Nonstop4h 31m
Copa Airlines
Deal found 1/26$482
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:18 am
RDU
-
PTY
1 stop8h 48m
Multiple Airlines
Fri 5/85:55 pm
PTY
-
RDU
2 stops36h 38m
Multiple Airlines
Deal found 1/27$486
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:18 am
RDU
-
PTY
1 stop12h 02m
Multiple Airlines
Wed 5/63:10 pm
PTY
-
RDU
2 stops15h 23m
Multiple Airlines
Deal found 1/27$488

Find flight deals from Durham to Panama City

Keep the following information in mind while searching for Durham to Panama City flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$437
(Trip.com)

One-way from

$193
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$455
Provider with most accurate pricing for Raleigh-Durham-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City Tocumen Intl flights.
Search Deals
From Durham to Panama City Tocumen Intl
Search Deals
One-way flight from Durham to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($117 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Durham to Panama City that are best for you.

Fly from

Durham

Fly to

Panama City

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sat 5/30

6:27 pm-4:04 am

1 stop10h 37m

Panama City Tocumen Intl

Sun 6/7

10:55 pm-8:56 am

1 stop9h 01m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 5/4

6:20 am-6:37 pm

2 stops13h 17m

Panama City Tocumen Intl

Fri 5/15

9:45 am-9:40 pm

1 stop10h 55m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 5/1

6:20 am-6:37 pm

2 stops13h 17m

Panama City Tocumen Intl

Tue 5/5

9:45 am-9:40 pm

1 stop10h 55m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Tue 5/26

6:33 am-2:14 pm

1 stop8h 41m

Panama City Tocumen Intl

Fri 5/29

10:00 am-9:55 pm

1 stop10h 55m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Thu 5/7

6:20 am-6:37 pm

2 stops13h 17m

Panama City Tocumen Intl

Sun 5/17

10:55 pm-8:59 am

1 stop9h 04m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 5/8

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Sun 5/17

10:55 pm-8:59 am

1 stop9h 04m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 4/15

6:30 am-2:14 pm

1 stop8h 44m

Panama City Tocumen Intl

Sun 4/19

3:30 pm-1:58 pm

2 stops21h 28m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 5/24

6:27 pm-4:04 am

1 stop10h 37m

Panama City Tocumen Intl

Fri 5/29

7:55 am-9:55 pm

1 stop13h 00m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 5/6

6:20 am-6:37 pm

2 stops13h 17m

Panama City Tocumen Intl

Sat 5/16

7:55 am-9:58 pm

1 stop13h 03m

$497

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Tue 4/21

6:30 am-4:12 pm

1 stop10h 42m

Panama City Tocumen Intl

Fri 4/24

3:30 pm-1:58 pm

2 stops21h 28m

$497

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 17 results
1
2

Best time to book a flight from Durham to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Panama City

How far ahead should I book a flight from Durham to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Panama City. Price data was last updated on January 23, 2026.

Booking 61 days in advance of your planned departure date is, on average, the best time to get cheap flights from Durham to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Durham to Panama City?

Currently, August is the cheapest month in which you can book a flight from Durham to Panama City (average of $234). Flying from Durham to Panama City in December is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to PTY?

Find hourly flight availability from Durham to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Durham to Panama City as you normally would.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from Durham to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,127 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,127 reviews
Delta
7.9
Good
8,127 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.5
Good
1,560 reviews
Delta
7.9
Good
8,127 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,215 reviews
Delta
7.9
Good
8,127 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,206 reviews
Delta
7.9
Good
8,127 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Durham?

    If you book a flight to Panama City from Durham, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Durham to Tocumen Intl per day from 4 different airlines.

  • How popular is this Durham to Panama City flight route?

    Flights from Durham to Panama City Tocumen Intl have been viewed 16 times in the past calendar month.

  • How long is the flight from Durham to Panama City?

    A quick flight from Durham to Panama City can take about 10h 37m. United Airlines provides one of the quickest options available for as low as $497. The distance between Durham and Panama City is about 1851 mi.

  • What are the cheapest flights from Durham to Panama City?

    While on average a flight from Durham to Panama City is generally $396, our data shows the cheapest flight currently is $105. When looking at the most popular route, (Raleigh-Durham - Panama City Tocumen Intl), you can expect to pay $424 for that flight.

  • Can I find deals for flights from Durham to Panama City that include hotel bookings?

    Yes. In addition to deals on Durham to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Panama City.

  • Can I find deals for business class flights from Durham to Panama City?

    Yes. Cheapflights offers flight deals from Durham to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Panama City?

    Currently, August is the cheapest month in which you can book a flight from Durham to Panama City (average of $234). Flying from Durham to Panama City in December is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Durham to Panama City

Discover the top 4 airlines that operate flights from Durham to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$588FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$352Average$501FlexibilityNo cancel feeOn-time70%
DeltaCheapest$367Average$541FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$495FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.