HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$178+ Cheap flights from Midway (MDW) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — PTY
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Midway to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Midway to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$465
(Delta)

One-way from

$178
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$479
From Chicago Midway to Panama City Tocumen Intl
Search Deals
One-way flight from Chicago Midway to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Midway to Panama City

Cheapest flights from Midway to Panama City
Explore the most affordable flight options available from Midway to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/296:00 amMDW - PTY
1 stop6h 55mDelta
lun. 10/62:21 pmPTY - MDW
1 stop7h 53mDelta
Deal found 9/11$465
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/196:00 amMDW - PTY
1 stop6h 55mDelta
mar. 9/302:10 pmPTY - MDW
2 stops18h 30mDelta
Deal found 9/10$470
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/196:00 amMDW - PTY
1 stop6h 55mDelta
vie. 10/32:10 pmPTY - MDW
1 stop19h 38mDelta
Deal found 9/10$474
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/2510:00 amMDW - PTY
2 stops22h 30mMultiple Airlines
sáb. 11/112:33 pmPTY - MDW
1 stop8h 49mMultiple Airlines
Deal found 9/10$562
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/134:24 pmMDW - PTY
1 stop15h 47mMultiple Airlines
vie. 10/178:10 pmPTY - MDW
2 stops26h 37mMultiple Airlines
Deal found 9/11$566
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/296:00 amMDW - PTY
1 stop12h 59mDelta
mié. 12/33:46 pmPTY - MDW
1 stop8h 46mDelta
Deal found 9/9$586
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/236:20 amMDW - PTY
1 stop13h 13mMultiple Airlines
jue. 10/309:25 amPTY - MDW
1 stop9h 14mMultiple Airlines
Deal found 9/10$590
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/16:00 amMDW - PTY
1 stop7h 12mDelta
sáb. 12/68:05 amPTY - MDW
1 stop8h 38mDelta
Deal found 9/10$602
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/176:00 amMDW - PTY
1 stop6h 55mDelta
mar. 9/302:10 pmPTY - MDW
2 stops22h 18mDelta
Deal found 9/10$619
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/206:15 amMDW - PTY
1 stop13h 18mMultiple Airlines
sáb. 9/279:25 amPTY - MDW
1 stop13h 52mMultiple Airlines
Deal found 9/10$621
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/176:00 amMDW - PTY
1 stop6h 55mDelta
jue. 10/22:10 pmPTY - MDW
1 stop19h 30mDelta
Deal found 9/10$623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama City that are best for you.

Fly from

Midway

Fly to

Panama City

Route

Depart

Return

Price

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 11/3

6:00 am-1:56 pm

1 stop6h 56m

Panama City Tocumen Intl

jue. 11/6

3:21 pm-10:14 pm

1 stop7h 53m

$465

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 9/22

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

jue. 10/2

2:10 pm-8:40 am

2 stops18h 30m

$470

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 9/22

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

mar. 9/30

2:10 pm-8:40 am

2 stops18h 30m

$470

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 9/22

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

mié. 10/1

2:10 pm-9:40 am

1 stop19h 30m

$474

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 9/22

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

vie. 10/3

2:10 pm-9:48 am

1 stop19h 38m

$474

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

sáb. 10/25

10:00 am-8:30 am

2 stops22h 30m

Panama City Tocumen Intl

sáb. 11/1

12:33 pm-9:22 pm

1 stop8h 49m

$562

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

mar. 3/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

mié. 3/11

2:20 pm-6:34 pm

2 stops28h 14m

$582

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

lun. 11/10

6:00 am-2:12 pm

1 stop7h 12m

Panama City Tocumen Intl

jue. 11/13

3:37 pm-11:32 pm

1 stop8h 55m

$586

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

vie. 10/24

12:18 pm-12:45 am

2 stops12h 27m

$178

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

mié. 11/5

2:06 pm-10:20 am

3 stops43h 14m

$203

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 15 results
1
2

Best time to book a flight from Midway to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Midway to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Chicago Midway?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl is the airport most travelers will use when flying to Panama City from Chicago Midway. Booking flights from Chicago Midway to Tocumen Intl (PTY) should be relatively easy as there are 0 daily inbound flights from Chicago Midway from 0 different airlines.

  • How long is the flight from Chicago Midway Airport to Panama City?

    Delta can get you from Chicago Midway Airport to Panama City in just under 6h 56m. Your travel time can differ by up to . The distance between Chicago Midway Airport and Panama City is about 2316 mi.

  • Can I find deals for flights from Midway to Panama City that include hotel bookings?

    Yes. In addition to deals on Midway to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Panama City.

  • Can I find deals for business class flights from Midway to Panama City?

    Yes. Cheapflights offers flight deals from Midway to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to Panama City (average of $478). Flying from Chicago Midway Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Midway to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Panama City flights
O'Hare Intl to David flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.