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Panama City Beach

$229+ Cheap flights from Knoxville (TYS) to Panama City Beach, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PNS
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Knoxville to Panama City Beach

Keep the following information in mind while searching for Knoxville to Panama City Beach flight deals. Data was last updated July 30, 2025.

Round-trip from

$259
(Delta)

One-way from

$229
(Delta)

Popular in

February

Cheapest in

August

Average price

$427
From Knoxville McGhee Tyson to Panama City Beach
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One-way flight from Knoxville McGhee Tyson to Panama City Beach
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Highest demand for flights based on searches. 7% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Panama City Beach

Cheapest flights from Knoxville to Panama City Beach
Explore the most affordable flight options available from Knoxville to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:10 pmTYS - ECP
1 stop5h 33mDelta
Tue 12/92:00 pmECP - TYS
1 stop3h 13mDelta
Deal found 7/27$259
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3012:42 pmTYS - ECP
1 stop6h 32mAmerican Airlines
Sun 8/315:30 amECP - TYS
1 stop4h 00mAmerican Airlines
Deal found 7/29$281
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:30 amTYS - ECP
1 stop11h 46mUnited Airlines
Mon 9/85:06 pmECP - TYS
2 stops28h 39mUnited Airlines
Deal found 7/30$540

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Panama City Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Knoxville to Panama City Beach that are best for you.

Fly from

Knoxville

Fly to

Panama City Beach

Route

Depart

Return

Price

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 9/20

5:45 am-9:55 am

1 stop5h 10m

Panama City NW Florida Beaches

Tue 9/23

2:05 pm-8:02 pm

1 stop4h 57m

$259

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 8/30

12:42 pm-6:14 pm

1 stop6h 32m

Panama City NW Florida Beaches

Sun 8/31

5:30 am-10:30 am

1 stop4h 00m

$281

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Thu 9/4

9:30 am-8:16 pm

1 stop11h 46m

Panama City NW Florida Beaches

Mon 9/8

5:06 pm-10:45 pm

2 stops28h 39m

$540

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sun 8/3

5:30 am-8:33 am

1 stop4h 03m

$229

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sun 8/24

2:54 pm-6:15 pm

1 stop4h 21m

$259

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Mon 9/22

4:40 pm-1:03 pm

2 stops21h 23m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Knoxville to Panama City Beach

Have a flexible travel schedule? Discover the best time to fly to Panama City Beach from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Panama City Beach

What is the cheapest month to book a flight from Knoxville to Panama City Beach?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Panama City Beach (average of $306). Flying from Knoxville to Panama City Beach in March is currently the most expensive (average of $417). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to PA9?

Find hourly flight availability from Knoxville to Panama City Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Panama City Beach as you normally would.

What is the cheapest day to fly from Knoxville to Panama City Beach?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Panama City Beach. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Panama City Beach flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Knoxville to Panama City Beach?

Reviews of airlines servicing Panama City Beach

Get insights into the airlines that provide service to Panama City Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City Beach. Reviews last updated July 30, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Panama City Beach to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Panama City Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Panama City Beach?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Panama City Beach. On average, McGhee Tyson has 0 outbound flights to Panama City Beach per day from 3 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Panama City Beach one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $229. Users have also found prices from $259 and $383 on American Airlines and United Airlines, respectively.

  • Can I find deals for flights from Knoxville to Panama City Beach that include hotel bookings?

    Yes. In addition to deals on Knoxville to Panama City Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Panama City Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Panama City Beach.

  • Can I find deals for business class flights from Knoxville to Panama City Beach?

    Yes. Cheapflights offers flight deals from Knoxville to Panama City Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Panama City Beach?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Panama City Beach (average of $306). Flying from Knoxville to Panama City Beach in March is currently the most expensive (average of $417). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Panama City Beach

Discover the top 3 airlines that operate flights from Knoxville to Panama City Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$72Average$112FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$182Average$447FlexibilityNo cancel feeOn-time71%
DeltaCheapest$223Average$422FlexibilityNo cancel feeOn-timeN/A

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