Palo Alto

$39+ Cheap flights from San Diego (SAN) to Palo Alto, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SFO
Oct 17 — Oct 241
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Cheapflights Tip: The best prices from San Diego to Palo Alto are usually found in January or February, booked 57 days in advance, depart on a Friday or Thursday and return on a Saturday

Cheap flight deals from San Diego to Palo Alto

Keep the following information in mind while searching for San Diego to Palo Alto flight deals. Data was last updated September 17, 2025.

Round-trip from

$77
(Southwest)

One-way from

$39
(Southwest)

Popular in

September

Cheapest in

January

Average price

$154
From San Diego to Palo Alto
One-way flight from San Diego to Palo Alto
Highest demand for flights based on searches. 9% potential increase in price ($13 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from San Diego to Palo Alto

Cheapest flights from San Diego to Palo Alto
Explore the most affordable flight options available from San Diego to Palo Alto. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/108:00 amSAN - SFO
Nonstop1h 42mUnited Airlines
Sun 10/126:15 amSFO - SAN
Nonstop1h 41mUnited Airlines
Deal found 9/16$77
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:28 pmSAN - SFO
Nonstop1h 45mFrontier
Mon 10/132:53 pmSFO - SAN
Nonstop1h 39mFrontier
Deal found 9/16$79
This Orbitz deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:28 pmSAN - SFO
Nonstop1h 45mMultiple Airlines
Sun 10/126:45 amSFO - SAN
Nonstop1h 44mMultiple Airlines
Deal found 9/15$80
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1712:12 pmSAN - SFO
Nonstop1h 52mFrontier
Thu 11/209:03 amSFO - SAN
Nonstop1h 45mFrontier
Deal found 9/16$81
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/110:57 amSAN - SFO
Nonstop1h 52mFrontier
Sat 11/87:30 pmSFO - SAN
Nonstop1h 45mFrontier
Deal found 9/17$82
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:28 pmSAN - SFO
Nonstop1h 45mFrontier
Sun 10/199:08 amSFO - SAN
Nonstop1h 48mFrontier
Deal found 9/16$83
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3012:17 pmSAN - SFO
Nonstop1h 52mFrontier
Fri 10/313:14 pmSFO - SAN
Nonstop1h 43mFrontier
Deal found 9/15$84
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/812:18 pmSAN - SFO
Nonstop1h 43mAlaska Airlines
Sun 10/126:45 amSFO - SAN
Nonstop1h 44mAlaska Airlines
Deal found 9/16$85
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:43 amSAN - SFO
Nonstop1h 56mFrontier
Mon 11/249:03 amSFO - SAN
Nonstop1h 45mFrontier
Deal found 9/16$86
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/58:10 amSAN - SFO
Nonstop1h 45mSouthwest
Sat 11/229:35 pmSFO - SAN
Nonstop1h 30mSouthwest
Deal found 9/15$87
This Trip.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/62:52 pmSAN - SFO
Nonstop1h 47mMultiple Airlines
Mon 10/69:17 pmSFO - SAN
Nonstop1h 43mMultiple Airlines
Deal found 9/17$89
This Trip.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/277:20 pmSAN - SFO
Nonstop1h 49mMultiple Airlines
Tue 9/307:10 amSFO - SAN
Nonstop1h 42mMultiple Airlines
Deal found 9/16$90

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Palo Alto that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from San Diego to Palo Alto that are best for you.

Fly from

San Diego

Fly to

Palo Alto

Route

Depart

Return

Price

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Tue 10/14

8:08 pm-9:48 pm

Nonstop1h 40m

San Francisco

Sat 10/18

10:36 pm-12:15 am

Nonstop1h 39m

$77

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Fri 10/10

8:08 pm-9:48 pm

Nonstop1h 40m

San Francisco

Wed 10/15

6:15 am-7:56 am

Nonstop1h 41m

$77

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Thu 12/4

3:05 pm-4:46 pm

Nonstop1h 41m

San Francisco

Wed 12/17

9:57 pm-11:30 pm

Nonstop1h 33m

$97

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Thu 10/16

11:00 am-12:45 pm

Nonstop1h 45m

San Francisco

Sat 10/18

4:35 pm-9:00 pm

1 stop4h 25m

$97

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Fri 12/12

3:10 pm-4:50 pm

Nonstop1h 40m

San Francisco

Sat 1/3

7:10 am-8:40 am

Nonstop1h 30m

$99

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Thu 10/30

2:55 pm-4:30 pm

Nonstop1h 35m

San Francisco

Sun 11/2

5:15 am-9:20 am

1 stop4h 05m

$99

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Wed 11/5

4:55 pm-6:35 pm

Nonstop1h 40m

San Francisco

Sat 11/22

8:25 pm-7:15 am

1 stop10h 50m

$102

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Mon 10/27

5:25 pm-11:45 pm

2 stops6h 20m

San Francisco

Thu 10/30

10:35 am-12:10 pm

Nonstop1h 35m

$102

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Wed 11/12

8:08 pm-10:01 pm

Nonstop1h 53m

$39

San DiegoSan Francisco

SAN - SFO

SANSFO

San Diego

Tue 10/21

10:38 am-12:20 pm

Nonstop1h 42m

$39

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 20 results
1
2

Best time to book a flight from San Diego to Palo Alto

Have a flexible travel schedule? Discover the best time to fly to Palo Alto from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Palo Alto

How far ahead should I book a flight from San Diego to Palo Alto?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Palo Alto. Price data was last updated on September 12, 2025.

The best time to book flights from San Diego to Palo Alto is 51 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Diego to Palo Alto?

Currently, January is the cheapest month in which you can book a flight from San Diego to Palo Alto (average of $276). Flying from San Diego to Palo Alto in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to P4L?

Find hourly flight availability from San Diego to Palo Alto. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from San Diego to Palo Alto as you normally would.

What is the cheapest day to fly from San Diego to Palo Alto?

Use this chart to determine the cheapest time to fly round-trip from San Diego to Palo Alto. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Diego to Palo Alto flight should consider departing on Thursday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Diego to Palo Alto

Explore weekly flight availability from San Diego to Palo Alto. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2025.

The most flights from SAN to P4L are scheduled on a Monday (90 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (54 on average).

Reviews of airlines servicing Palo Alto

Get insights into the airlines that provide service to Palo Alto. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Palo Alto. Reviews last updated September 17, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest, and Hawaiian Airlines from San Diego to Palo Alto to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.8

Boarding

8.1

Food

7.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Comfort

7.8

Boarding

8.1

Food

7.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Comfort

7.8

Boarding

8.1

Food

7.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Comfort

7.8

Boarding

8.1

Food

7.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Comfort

7.8

Boarding

8.1

Food

7.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Comfort

7.8

Boarding

8.1

Food

7.1

Crew

8.5

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Palo Alto. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to Palo Alto?

    Located just 2.6 mi from the city center, San Diego is the airport most travelers will use when flying to Palo Alto from San Diego. Booking flights from San Diego (SAN) to Palo Alto should be relatively easy as there are 76 daily outbound flights to Palo Alto from 8 different airlines.

  • How popular is this San Diego to Palo Alto flight route?

  • How long is the flight from San Diego to Palo Alto?

    There are many flights that can get you from San Diego to Palo Alto in 1h 40m. Fly via United Airlines, Hawaiian Airlines, or Southwest to get the fastest option. There are 446 mi between San Diego and Palo Alto. Generally, flights for this route are nonstop.

  • What are the cheapest airlines to fly from San Diego to Palo Alto one-way?

    The cheapest airline one-way is Alaska Airlines, with whom users have recently found tickets for as low as $39. However, be on the lookout for offers from United Airlines and Southwest, as they are both options that can get you from San Diego to Palo Alto for a low price.

  • What are the most reliable airlines from San Diego to Palo Alto?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from San Diego to Palo Alto on time: ITA Airways (100%), Iberia (89%), Qantas Airways (89%).

  • What are the cheapest flights from San Diego to Palo Alto?

    Looking at all options, your cheapest flight can be booked for $38. While the most popular route (San Diego - San Francisco) can be booked for $55 on average, our data indicates $679 when flying from San Diego to Palo Alto.

  • Can I find deals for flights from San Diego to Palo Alto that include hotel bookings?

    Yes. In addition to deals on San Diego to Palo Alto flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Palo Alto?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Palo Alto.

  • Can I find deals for business class flights from San Diego to Palo Alto?

    Yes. Cheapflights offers flight deals from San Diego to Palo Alto by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Palo Alto?

    Currently, January is the cheapest month in which you can book a flight from San Diego to Palo Alto (average of $276). Flying from San Diego to Palo Alto in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to Palo Alto

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from San Diego to Palo Alto

Discover the top 8 airlines that operate flights from San Diego to Palo Alto. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$27Average$94FlexibilityNo cancel feeOn-time65%
FrontierCheapest$28Average$78FlexibilityNo cancel feeOn-time62%
Hawaiian AirlinesCheapest$29Average$137FlexibilityNo cancel feeOn-time85%
United AirlinesCheapest$57Average$194FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$57Average$191FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$79Average$184FlexibilityNo cancel feeOn-time63%
DeltaCheapest$88Average$176FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$158Average$366FlexibilityNo cancel feeOn-time71%

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