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$284+ Cheap flights from Florence, SC (FLO) to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — CVG
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Florence to Ohio

Cheapest flights from Florence to Ohio
Explore the most affordable flight options available from Florence to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:20 am
FLO
-
DTW
1 stop4h 07m
American Airlines
Mon 4/133:30 pm
DTW
-
FLO
1 stop6h 17m
American Airlines
Deal found 3/10$343
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:15 am
FLO
-
DTW
1 stop6h 08m
American Airlines
Tue 4/2811:12 am
DTW
-
FLO
1 stop4h 20m
American Airlines
Deal found 3/8$373
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:20 am
FLO
-
DTW
1 stop4h 07m
American Airlines
Wed 4/2911:57 am
DTW
-
FLO
1 stop3h 53m
American Airlines
Deal found 3/8$393
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:20 am
FLO
-
DTW
1 stop4h 07m
American Airlines
Sat 5/211:55 am
DTW
-
FLO
2 stops9h 52m
American Airlines
Deal found 3/8$398
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:16 am
FLO
-
DTW
1 stop4h 09m
American Airlines
Sat 3/1411:36 am
DTW
-
FLO
1 stop6h 14m
American Airlines
Deal found 3/8$402
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:02 pm
FLO
-
DTW
2 stops7h 23m
American Airlines
Sun 4/266:00 am
DTW
-
FLO
2 stops9h 50m
American Airlines
Deal found 3/8$403
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:20 am
FLO
-
DTW
1 stop4h 07m
American Airlines
Mon 4/273:30 pm
DTW
-
FLO
1 stop6h 17m
American Airlines
Deal found 3/8$413
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:05 am
FLO
-
PIT
1 stop3h 49m
American Airlines
Sun 6/283:30 pm
PIT
-
FLO
1 stop6h 30m
American Airlines
Deal found 3/9$521
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:05 am
FLO
-
CVG
1 stop3h 38m
American Airlines
Mon 5/255:28 pm
CVG
-
FLO
1 stop4h 32m
American Airlines
Deal found 3/10$555
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:16 am
FLO
-
PIT
1 stop3h 55m
American Airlines
Mon 4/135:58 pm
PIT
-
FLO
1 stop3h 49m
American Airlines
Deal found 3/9$565
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:20 pm
FLO
-
CVG
1 stop5h 39m
American Airlines
Sun 3/292:16 pm
CVG
-
FLO
1 stop3h 34m
American Airlines
Deal found 3/10$580
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:20 pm
FLO
-
HTS
1 stop5h 38m
American Airlines
Sun 3/293:34 pm
HTS
-
FLO
1 stop49h 47m
American Airlines
Deal found 3/10$856

Find flight deals from Florence to Ohio

Keep the following information in mind while searching for Florence to Ohio flight deals. Data was last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$343
(American Airlines)

One-way from

$284
(American Airlines)
Provider with most accurate pricing for Florence-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Cleveland Hopkins Intl flights.
Search Deals
From Florence to Ohio
Search Deals
One-way flight from Florence to Ohio
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Florence to Ohio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Fri 4/10

5:20 am-9:27 am

1 stop4h 07m

Detroit Metropolitan Wayne County

Mon 4/13

3:30 pm-9:47 pm

1 stop6h 17m

$343

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Tue 4/21

6:15 am-12:23 pm

1 stop6h 08m

Detroit Metropolitan Wayne County

Wed 4/29

3:30 pm-9:47 pm

1 stop6h 17m

$373

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Tue 4/21

6:15 am-12:23 pm

1 stop6h 08m

Detroit Metropolitan Wayne County

Tue 4/28

11:12 am-3:32 pm

1 stop4h 20m

$373

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Wed 4/22

5:20 am-9:27 am

1 stop4h 07m

Detroit Metropolitan Wayne County

Mon 4/27

3:30 pm-9:47 pm

1 stop6h 17m

$393

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Tue 4/21

4:02 pm-12:45 am

2 stops8h 43m

Detroit Metropolitan Wayne County

Sun 4/26

11:57 am-3:50 pm

1 stop3h 53m

$398

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Thu 4/23

5:20 am-11:17 am

1 stop5h 57m

Detroit Metropolitan Wayne County

Tue 4/28

5:00 am-3:32 pm

2 stops10h 32m

$398

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Thu 4/23

5:20 am-11:17 am

1 stop5h 57m

Detroit Metropolitan Wayne County

Mon 4/27

3:30 pm-9:47 pm

1 stop6h 17m

$413

FlorencePittsburgh

FLO - PIT

FLOPIT

Florence

Thu 6/18

5:05 am-8:54 am

1 stop3h 49m

Pittsburgh

Sun 6/28

3:30 pm-10:00 pm

1 stop6h 30m

$521

FlorenceCincinnati

FLO - CVG

FLOCVG

Florence

Sat 5/23

5:05 am-8:43 am

1 stop3h 38m

Cincinnati Cinci./N. Kentucky

Mon 5/25

5:28 pm-10:00 pm

1 stop4h 32m

$555
Quickest round-trip

FlorencePittsburgh

FLO - PIT

FLOPIT

Florence

Mon 4/6

5:16 am-9:11 am

1 stop3h 55m

Pittsburgh

Mon 4/13

5:58 pm-9:47 pm

1 stop3h 49m

$565

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Showing 1-10 of 19 resultsSorted by cheapest first
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Best time to book a flight from Florence to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Ohio

What is the cheapest month to book a flight from Florence, South Carolina to Ohio?

Currently, March is the cheapest month in which you can book a flight from Florence, South Carolina to Ohio (average of $40). Flying from Florence, South Carolina to Ohio in January is currently the most expensive (average of $103). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Ohio?

    Most people fly from Florence (FLO) if they book a flight from Florence to Ohio. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Florence, South Carolina to Ohio?

    There are many flights that can get you from Florence, South Carolina to Ohio in 4h 07m. Fly via American Airlines to get the fastest option. The distance between Florence, South Carolina and Ohio is about 589 mi.

  • What are the most popular routes from Florence, South Carolina to Ohio?

    The most popular flight routes from Florence, South Carolina to Ohio are Florence - Cincinnati Cinci./N. Kentucky, Florence - Detroit Metropolitan Wayne County and Florence - Pittsburgh.

  • Can I find deals for flights from Florence to Ohio that include hotel bookings?

    Yes. In addition to deals on Florence to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Ohio.

  • Can I find deals for business class flights from Florence to Ohio?

    Yes. Cheapflights offers flight deals from Florence to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Ohio?

    Currently, March is the cheapest month in which you can book a flight from Florence, South Carolina to Ohio (average of $40). Flying from Florence, South Carolina to Ohio in January is currently the most expensive (average of $103). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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