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$469+ Cheap flights from Florence, SC (FLO) to Ohio

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — CVG
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Florence to Ohio

Cheapest flights from Florence to Ohio
Explore the most affordable flight options available from Florence to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:15 amFLO - PIT
1 stop3h 54mAmerican Airlines
Sat 12/206:10 amPIT - FLO
1 stop6h 16mAmerican Airlines
Deal found 12/9$469
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1611:15 amFLO - PIT
1 stop6h 12mAmerican Airlines
Sun 12/218:11 pmPIT - FLO
1 stop4h 04mAmerican Airlines
Deal found 12/9$519
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:51 pmFLO - CVG
1 stop5h 39mAmerican Airlines
Sun 12/287:00 pmCVG - FLO
1 stop5h 15mAmerican Airlines
Deal found 12/10$520
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:15 amFLO - HTS
1 stop5h 27mAmerican Airlines
Fri 12/265:00 amHTS - FLO
1 stop31h 42mAmerican Airlines
Deal found 12/10$825

Find flight deals from Florence to Ohio

Keep the following information in mind while searching for Florence to Ohio flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$520
(American Airlines)
Provider with most accurate pricing for Florence-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Cleveland Hopkins Intl flights.
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From Florence to Ohio
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Florence to Ohio that are best for you.

Fly from

Florence

Fly to

Ohio

Route

Depart

Return

Price

FlorenceCincinnati

FLO - CVG

FLOCVG

Florence

Wed 12/24

12:51 pm-6:30 pm

1 stop5h 39m

Cincinnati Cinci./N. Kentucky

Sun 12/28

7:00 pm-12:15 am

1 stop5h 15m

$520

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Mon 1/5

6:30 pm-5:25 pm

2 stops22h 55m

Detroit Metropolitan Wayne County

Wed 1/7

8:00 am-10:43 pm

2 stops14h 43m

$692

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Tue 1/6

6:15 am-8:18 pm

2 stops14h 03m

Detroit Metropolitan Wayne County

Wed 1/7

8:00 am-10:43 pm

2 stops14h 43m

$713

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Mon 1/5

6:30 pm-5:25 pm

2 stops22h 55m

Detroit Metropolitan Wayne County

Thu 1/8

8:00 am-10:43 pm

2 stops14h 43m

$719

FlorenceHuntington

FLO - HTS

FLOHTS

Florence

Mon 12/22

5:15 am-10:42 am

1 stop5h 27m

Huntington Tri State

Fri 12/26

5:00 am-12:42 pm

1 stop31h 42m

$825

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Tue 1/6

5:36 pm-10:10 pm

1 stop4h 34m

Detroit Metropolitan Wayne County

Thu 1/8

5:03 pm-10:43 pm

1 stop5h 40m

$841

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Best time to book a flight from Florence to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Ohio

What is the cheapest month to book a flight from Florence, South Carolina to Ohio?

Currently, October is the cheapest month in which you can book a flight from Florence, South Carolina to Ohio (average of $40). Flying from Florence, South Carolina to Ohio in January is currently the most expensive (average of $81). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated December 12, 2025.
See what other customers who have flown with American Airlines from Florence to Ohio have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Food

6.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Food

6.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Florence to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Ohio?

    Most people fly from Florence (FLO) if they book a flight from Florence to Ohio. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Florence, South Carolina to Ohio?

    There are many flights that can get you from Florence, South Carolina to Ohio in 5h 29m. Fly via American Airlines to get the fastest option. The distance between Florence, South Carolina and Ohio is about 474 mi.

  • What are the most popular routes from Florence, South Carolina to Ohio?

    The most popular flight routes from Florence, South Carolina to Ohio are Florence - Pittsburgh, Florence - Detroit Metropolitan Wayne County and Florence - Akron/Canton.

  • Can I find deals for flights from Florence to Ohio that include hotel bookings?

    Yes. In addition to deals on Florence to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Ohio.

  • Can I find deals for business class flights from Florence to Ohio?

    Yes. Cheapflights offers flight deals from Florence to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Ohio?

    Currently, October is the cheapest month in which you can book a flight from Florence, South Carolina to Ohio (average of $40). Flying from Florence, South Carolina to Ohio in January is currently the most expensive (average of $81). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Florence to Ohio

Discover the top airline that operate flights from Florence to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$380Average$595FlexibilityNo cancel feeOn-time71%

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