HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Odessa

$284+ Cheap flights from Fort Myers (RSW) to Odessa, TX

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — MAF
Jun 8 — Jun 151
Mon 6/8
Mon 6/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Fort Myers to Odessa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Fort Myers to Odessa

Cheapest flights from Fort Myers to Odessa
Explore the most affordable flight options available from Fort Myers to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.

This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:45 am
RSW
-
MAF
2 stops9h 55m
Southwest
Thu 8/205:50 am
MAF
-
RSW
2 stops9h 40m
Southwest
Deal found 5/8$406
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:00 pm
RSW
-
MAF
1 stop7h 37m
United Airlines
Wed 8/197:00 am
MAF
-
RSW
1 stop7h 52m
United Airlines
Deal found 5/4$457
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:10 am
RSW
-
MAF
2 stops10h 50m
American Airlines
Thu 8/205:00 am
MAF
-
RSW
1 stop7h 22m
American Airlines
Deal found 5/8$463
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:00 am
RSW
-
MAF
1 stop7h 45m
American Airlines
Sun 5/242:21 pm
MAF
-
RSW
1 stop7h 00m
American Airlines
Deal found 5/6$507
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:00 am
RSW
-
MAF
2 stops8h 51m
American Airlines
Wed 5/275:00 am
MAF
-
RSW
1 stop4h 54m
American Airlines
Deal found 5/8$516
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:05 pm
RSW
-
MAF
2 stops8h 55m
Southwest
Wed 5/2712:30 pm
MAF
-
RSW
2 stops7h 05m
Southwest
Deal found 5/8$537
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:20 am
RSW
-
MAF
1 stop10h 50m
Southwest
Sat 5/236:50 am
MAF
-
RSW
1 stop8h 25m
Southwest
Deal found 5/4$608

Find flight deals from Fort Myers to Odessa

Keep the following information in mind while searching for Fort Myers to Odessa flight deals. Data was last updated May 9, 2026.

Round-trip from

$406
(Southwest)

One-way from

$284
(American Airlines)
From Fort Myers SW Florida Intl to Odessa
Search Deals
One-way flight from Fort Myers SW Florida Intl to Odessa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from Fort Myers to Odessa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 8/18

8:45 am-5:40 pm

2 stops9h 55m

Midland Intl

Thu 8/20

5:50 am-4:30 pm

2 stops9h 40m

$406
Quickest round-trip

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 8/18

5:00 pm-11:37 pm

1 stop7h 37m

Midland Intl

Wed 8/19

7:00 am-3:52 pm

1 stop7h 52m

$457

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 8/18

7:10 am-5:00 pm

2 stops10h 50m

Midland Intl

Thu 8/20

5:00 am-1:22 pm

1 stop7h 22m

$463

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Sat 5/23

1:05 pm-9:00 pm

2 stops8h 55m

Midland Intl

Wed 5/27

12:30 pm-8:35 pm

2 stops7h 05m

$537

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Wed 5/20

12:21 pm-10:07 pm

2 stops10h 46m

Midland Intl

Sun 5/24

7:00 am-5:43 pm

2 stops9h 43m

$576

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 5/19

6:05 am-2:05 pm

2 stops9h 00m

Midland Intl

Sat 5/23

6:50 am-4:15 pm

1 stop8h 25m

$608
Cheapest one-way
Quickest one-way

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Sat 5/23

6:24 pm-11:16 pm

1 stop5h 52m

$284

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Mon 5/18

5:15 pm-11:15 pm

1 stop7h 00m

$459

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Sun 5/17

7:00 am-1:45 pm

1 stop7h 45m

$459

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 5/19

7:00 am-12:09 pm

1 stop6h 09m

$459

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/4

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Fort Myers to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Odessa
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Odessa

Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated May 9, 2026.
Peruse reviews from past customers who have flown with American Airlines from Fort Myers to Odessa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,669 reviews

Boarding

7.5

Entertainment

6.9

Food

6.4

Crew

7.9

Overall

7.1

Comfort

7.2

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.1
Good
11,669 reviews
American Airlines
7.1
Good
11,669 reviews

Boarding

7.5

Entertainment

6.9

Food

6.4

Crew

7.9

Overall

7.1

Comfort

7.2

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Odessa?

    Located just 10.0 mi from the city center, Fort Myers SW Florida Intl is the airport most travelers will use when flying to Odessa from Fort Myers. Booking flights from SW Florida Intl (RSW) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 1 airline.

  • How long is the flight from Fort Myers to Odessa?

    For as low as $457, Southwest can have you in Odessa from Fort Myers in 7h 37m. Airlines will cover a distance of 1285 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Fort Myers to Odessa that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Odessa.

  • Can I find deals for business class flights from Fort Myers to Odessa?

    Yes. Cheapflights offers flight deals from Fort Myers to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Fort Myers to Odessa

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to Dallas/Fort Worth flights
Orlando to Hobby flights
Fort Lauderdale to Dallas/Fort Worth flights
Fort Lauderdale to Hobby flights
Miami to Hobby flights
Miami to Dallas/Fort Worth flights
Orlando to George Bush Intcntl flights
Tampa to Dallas/Fort Worth flights
Fort Lauderdale to George Bush Intcntl flights
Miami to George Bush Intcntl flights
Tampa to Hobby flights
Orlando to Austin flights
Tampa to George Bush Intcntl flights
Jacksonville to Dallas/Fort Worth flights
Fort Lauderdale to Love Field flights
Fort Lauderdale to Austin flights
Tampa to Austin flights
Miami to Austin flights
Miami to Love Field flights
West Palm Beach to Dallas/Fort Worth flights
Orlando to Love Field flights
Orlando to San Antonio flights
Tampa to Love Field flights
Tampa to San Antonio flights
West Palm Beach to Hobby flights
Jacksonville to Hobby flights
Fort Myers to Dallas/Fort Worth flights
Jacksonville to Love Field flights
West Palm Beach to George Bush Intcntl flights
Pensacola to Dallas/Fort Worth flights
Fort Myers to Hobby flights
Jacksonville to George Bush Intcntl flights
Fort Myers to George Bush Intcntl flights
Miami to San Antonio flights
Pensacola to Hobby flights
Jacksonville to Austin flights
Sarasota to Dallas/Fort Worth flights
Fort Lauderdale to San Antonio flights
Pensacola to George Bush Intcntl flights
West Palm Beach to Austin flights
Sarasota to Hobby flights
Fort Myers to Austin flights
Panama City to Dallas/Fort Worth flights
Panama City to Hobby flights
West Palm Beach to Love Field flights
Jacksonville to San Antonio flights
Orlando to El Paso flights
Sarasota to George Bush Intcntl flights
West Palm Beach to San Antonio flights
Panama City to George Bush Intcntl flights

Top airline flying from Fort Myers to Odessa

Discover the top airline that operate flights from Fort Myers to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$632FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights