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Odessa

$346+ Cheap flights from Fort Myers (RSW) to Odessa, TX

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — MAF
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Fort Myers to Odessa

Cheapest flights from Fort Myers to Odessa
Explore the most affordable flight options available from Fort Myers to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:08 pmRSW - MAF
1 stop7h 17mUnited Airlines
Sun 1/45:00 amMAF - RSW
1 stop4h 40mUnited Airlines
Deal found 12/16$445
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:27 amRSW - MAF
2 stops10h 31mAmerican Airlines
Sun 1/412:22 pmMAF - RSW
1 stop6h 47mAmerican Airlines
Deal found 12/17$566
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:27 pmRSW - MAF
1 stop16h 14mAmerican Airlines
Fri 1/210:19 amMAF - RSW
1 stop7h 06mAmerican Airlines
Deal found 12/17$578
This Southwest deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amRSW - MAF
2 stops8h 45mSouthwest
Sun 1/47:35 amMAF - RSW
2 stops8h 45mSouthwest
Deal found 12/17$591
This Southwest deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:55 pmRSW - MAF
1 stop6h 10mSouthwest
Fri 1/29:45 amMAF - RSW
1 stop6h 35mSouthwest
Deal found 12/17$732

Find flight deals from Fort Myers to Odessa

Keep the following information in mind while searching for Fort Myers to Odessa flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$346
(United Airlines)
Provider with most accurate pricing for Fort Myers SW Florida Intl-Midland Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Midland Intl flights.
Search Deals
From Fort Myers SW Florida Intl to Odessa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Fort Myers to Odessa that are best for you.

Fly from

Fort Myers

Fly to

Odessa

Route

Depart

Return

Price

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 1/6

5:02 pm-9:54 pm

1 stop5h 52m

Midland Intl

Wed 1/7

7:20 am-3:20 pm

1 stop7h 00m

$346

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Sat 2/14

6:50 am-1:48 pm

1 stop7h 58m

Midland Intl

Wed 2/18

7:00 am-3:43 pm

1 stop7h 43m

$375

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Wed 2/18

4:57 pm-9:44 pm

1 stop5h 47m

Midland Intl

Sat 2/21

9:43 am-3:43 pm

1 stop5h 00m

$406

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 1/6

5:02 pm-9:54 pm

1 stop5h 52m

Midland Intl

Thu 1/8

7:20 am-8:33 pm

2 stops12h 13m

$419

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Wed 12/31

5:08 pm-11:25 pm

1 stop7h 17m

Midland Intl

Sun 1/4

5:00 am-10:40 am

1 stop4h 40m

$445

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 1/6

7:50 am-4:15 pm

2 stops9h 25m

Midland Intl

Wed 1/7

11:05 am-7:50 pm

2 stops7h 45m

$508

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 1/6

7:50 am-4:15 pm

2 stops9h 25m

Midland Intl

Thu 1/8

11:05 am-7:50 pm

2 stops7h 45m

$518

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 12/30

5:27 pm-8:41 am

1 stop16h 14m

Midland Intl

Fri 1/2

10:19 am-6:25 pm

1 stop7h 06m

$578

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Best time to book a flight from Fort Myers to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Odessa

What is the cheapest time of day to fly from RSW to OD3?

Find hourly flight availability from Fort Myers to Odessa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

A simple way to save on the total cost of your ticket is to fly from Fort Myers to Odessa in the evening. If you’re flexible enough to do this you can expect to save up to 26% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Odessa

Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated December 18, 2025.
Peruse reviews from past customers who have flown with American Airlines from Fort Myers to Odessa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,055 reviews

Crew

8.0

Food

6.5

Overall

7.2

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,055 reviews
American Airlines
7.2
Good
11,055 reviews

Crew

8.0

Food

6.5

Overall

7.2

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Odessa?

    Located just 10.0 mi from the city center, Fort Myers SW Florida Intl is the airport most travelers will use when flying to Odessa from Fort Myers. Booking flights from SW Florida Intl (RSW) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 1 airline.

  • How long is the flight from Fort Myers to Odessa?

    For as low as $346, United Airlines can have you in Odessa from Fort Myers in 5h 52m. Airlines will cover a distance of 1285 mi.

  • Can I find deals for flights from Fort Myers to Odessa that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Odessa.

  • Can I find deals for business class flights from Fort Myers to Odessa?

    Yes. Cheapflights offers flight deals from Fort Myers to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Fort Myers to Odessa

Discover the top airline that operate flights from Fort Myers to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$632FlexibilityNo cancel feeOn-time71%

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