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Odessa

$377+ Cheap flights from Fort Myers (RSW) to Odessa, TX

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — MAF
Apr 25 — May 21
Sat 4/25
Sat 5/2
1 adult, Economy
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Cheap flight deals from Fort Myers to Odessa

Cheapest flights from Fort Myers to Odessa
Explore the most affordable flight options available from Fort Myers to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.

This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:15 pm
RSW
-
MAF
1 stop5h 31m
United Airlines
Wed 5/611:45 am
MAF
-
RSW
1 stop7h 07m
United Airlines
Deal found 3/25$377
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:21 pm
RSW
-
MAF
1 stop6h 38m
American Airlines
Tue 8/42:37 pm
MAF
-
RSW
1 stop7h 09m
American Airlines
Deal found 3/24$447
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:05 am
RSW
-
MAF
2 stops10h 50m
Southwest
Sun 9/68:20 am
MAF
-
RSW
2 stops9h 05m
Southwest
Deal found 3/26$457
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:02 pm
RSW
-
MAF
1 stop7h 13m
United Airlines
Mon 4/202:13 pm
MAF
-
RSW
1 stop6h 46m
United Airlines
Deal found 3/22$487
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:50 am
RSW
-
MAF
2 stops9h 10m
Southwest
Mon 4/206:00 am
MAF
-
RSW
2 stops9h 45m
Southwest
Deal found 3/22$497
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:58 am
RSW
-
MAF
2 stops10h 34m
American Airlines
Sun 9/65:00 am
MAF
-
RSW
1 stop5h 01m
American Airlines
Deal found 3/26$498

Find flight deals from Fort Myers to Odessa

Keep the following information in mind while searching for Fort Myers to Odessa flight deals. Data was last updated March 26, 2026.

Round-trip from

$377
(United Airlines)
From Fort Myers SW Florida Intl to Odessa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Fort Myers to Odessa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 5/5

5:15 pm-9:46 pm

1 stop5h 31m

Midland Intl

Wed 5/6

7:00 am-3:57 pm

1 stop7h 57m

$377
Quickest round-trip

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Fri 9/4

5:00 pm-9:27 pm

1 stop5h 27m

Midland Intl

Sun 9/6

7:30 am-3:23 pm

1 stop6h 53m

$447

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Fri 4/17

5:02 pm-11:15 pm

1 stop7h 13m

Midland Intl

Mon 4/20

2:13 pm-9:59 pm

1 stop6h 46m

$487

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Fri 4/17

6:50 am-3:00 pm

2 stops9h 10m

Midland Intl

Mon 4/20

6:00 am-4:45 pm

2 stops9h 45m

$497

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Thu 7/30

9:58 am-6:10 pm

2 stops9h 12m

Midland Intl

Tue 8/4

5:00 am-3:09 pm

2 stops9h 09m

$512

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Sorted by cheapest first

Best time to book a flight from Fort Myers to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Odessa
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Odessa

Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated March 26, 2026.
Peruse reviews from past customers who have flown with American Airlines from Fort Myers to Odessa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,495 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Crew

7.9

Food

6.4

Overall

7.1

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.1
Good
11,495 reviews
American Airlines
7.1
Good
11,495 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Crew

7.9

Food

6.4

Overall

7.1

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Odessa?

    Located just 10.0 mi from the city center, Fort Myers SW Florida Intl is the airport most travelers will use when flying to Odessa from Fort Myers. Booking flights from SW Florida Intl (RSW) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 1 airline.

  • How long is the flight from Fort Myers to Odessa?

    For as low as $377, United Airlines can have you in Odessa from Fort Myers in 5h 31m. Airlines will cover a distance of 1285 mi.

  • Can I find deals for flights from Fort Myers to Odessa that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Odessa.

  • Can I find deals for business class flights from Fort Myers to Odessa?

    Yes. Cheapflights offers flight deals from Fort Myers to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Fort Myers to Odessa

Discover the top airline that operate flights from Fort Myers to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$632FlexibilityNo cancel feeOn-time71%

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