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Panama City

$255+ Cheap flights from South Dakota to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — ECP
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheap flight deals from South Dakota to Panama City

Keep the following information in mind while searching for South Dakota to Panama City flight deals. Data was last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$264
(Delta)

Popular in

December

Cheapest in

January

Average price

$394
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flights.
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From South Dakota to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 0% potential increase in price ($3 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from South Dakota to Panama City

Cheapest flights from South Dakota to Panama City
Explore the most affordable flight options available from South Dakota to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:00 pmFSD - ECP
2 stops7h 37mDelta
Tue 12/95:00 pmECP - FSD
1 stop6h 14mDelta
Deal found 10/22$264
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/174:19 pmFSD - ECP
2 stops6h 48mDelta
Sun 11/234:26 pmECP - FSD
1 stop6h 43mDelta
Deal found 10/21$304
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/61:09 pmFSD - ECP
1 stop6h 02mAmerican Airlines
Tue 12/93:18 pmECP - FSD
1 stop5h 46mAmerican Airlines
Deal found 10/20$339
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amFSD - ECP
2 stops10h 03mUnited Airlines
Fri 11/143:00 pmECP - FSD
2 stops25h 18mUnited Airlines
Deal found 10/22$478
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:30 amFSD - ECP
1 stop6h 11mAmerican Airlines
Fri 11/143:19 pmECP - FSD
1 stop25h 20mAmerican Airlines
Deal found 10/23$507
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/48:57 amFSD - ECP
2 stops12h 52mUnited Airlines
Fri 11/75:00 pmECP - FSD
2 stops27h 23mUnited Airlines
Deal found 10/23$538
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/171:43 pmFSD - ECP
2 stops9h 32mAmerican Airlines
Sun 11/237:15 amECP - FSD
2 stops16h 44mAmerican Airlines
Deal found 10/21$556

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from South Dakota to Panama City that are best for you.

Fly from

South Dakota

Fly to

Panama City

Route

Depart

Return

Price

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Sat 12/6

3:00 pm-10:37 pm

2 stops7h 37m

Panama City NW Florida Beaches

Tue 12/9

5:00 pm-11:14 pm

1 stop6h 14m

$264

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Mon 11/17

4:19 pm-11:07 pm

2 stops6h 48m

Panama City NW Florida Beaches

Sun 11/23

4:26 pm-11:09 pm

1 stop6h 43m

$304

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Mon 1/12

1:20 pm-10:42 pm

2 stops9h 22m

Panama City NW Florida Beaches

Sat 1/17

7:45 am-7:18 pm

2 stops11h 33m

$309

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Sat 12/6

1:09 pm-7:11 pm

1 stop6h 02m

Panama City NW Florida Beaches

Tue 12/9

3:18 pm-9:04 pm

1 stop5h 46m

$339

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Tue 1/27

7:30 am-12:02 pm

2 stops28h 32m

$255

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Mon 1/26

1:23 pm-9:19 pm

1 stop7h 56m

$271

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Tue 1/27

1:23 pm-9:19 pm

1 stop7h 56m

$271

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Mon 1/26

1:20 pm-10:42 pm

2 stops9h 22m

$276

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Mon 1/26

9:00 am-9:59 pm

3 stops12h 59m

$523

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/23

Best time to book a flight from South Dakota to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Panama City

What is the cheapest month to book a flight from South Dakota to Panama City, Florida?

Currently, July is the cheapest month in which you can book a flight from South Dakota to Panama City, Florida (average of $198). Flying from South Dakota to Panama City, Florida in June is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from South Dakota?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from South Dakota to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from South Dakota to Panama City, Florida?

    Airlines like Delta fly from South Dakota to Panama City, Florida in about 7h 37m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 1092 mi.

  • What are the cheapest airlines to fly from South Dakota to Panama City, Florida one-way?

    The cheapest airlines for a one-way flight from South Dakota to Panama City, Florida are United Airlines ($255), American Airlines ($271), and Delta ($276).

  • Can I find deals for flights from South Dakota to Panama City that include hotel bookings?

    Yes. In addition to deals on South Dakota to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Panama City.

  • Can I find deals for business class flights from South Dakota to Panama City?

    Yes. Cheapflights offers flight deals from South Dakota to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Panama City, Florida?

    Currently, July is the cheapest month in which you can book a flight from South Dakota to Panama City, Florida (average of $198). Flying from South Dakota to Panama City, Florida in June is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top 3 airlines flying from South Dakota to Panama City

Discover the top 3 airlines that operate flights from South Dakota to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$254Average$408FlexibilityNo cancel feeOn-time69%
DeltaCheapest$264Average$394FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$274Average$511FlexibilityNo cancel feeOn-time71%

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