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Panama City

$284+ Cheap flights from South Dakota to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — ECP
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from South Dakota to Panama City

Best flights from South Dakota to Panama City
Discover carefully curated flight deals from South Dakota to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:14 pmFSD - ECP
2 stops11h 35mAmerican Airlines
Wed 4/86:55 amECP - FSD
1 stop5h 24mAmerican Airlines
Deal found 12/17$284
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/96:00 amFSD - ECP
2 stops10h 12mUnited Airlines
Mon 1/121:10 pmECP - FSD
2 stops10h 34mUnited Airlines
Deal found 12/16$319
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/216:00 amFSD - ECP
2 stops11h 33mAmerican Airlines
Thu 1/293:27 pmECP - FSD
1 stop6h 37mAmerican Airlines
Deal found 12/17$284
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/287:30 amFSD - ECP
2 stops8h 42mUnited Airlines
Sat 1/316:30 amECP - FSD
2 stops10h 07mUnited Airlines
Deal found 12/16$429
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/96:00 amFSD - ECP
2 stops11h 33mAmerican Airlines
Mon 1/123:27 pmECP - FSD
1 stop6h 37mAmerican Airlines
Deal found 12/16$406
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:52 pmFSD - ECP
1 stop16h 38mAmerican Airlines
Mon 3/21:06 pmECP - FSD
1 stop22h 43mAmerican Airlines
Deal found 12/15$407

Find flight deals from South Dakota to Panama City

Keep the following information in mind while searching for South Dakota to Panama City flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$284
(American Airlines)

Popular in

December

Cheapest in

January

Average price

$639
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flights.
Search Deals
From South Dakota to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South Dakota to Panama City that are best for you.

Fly from

South Dakota

Fly to

Panama City

Route

Depart

Return

Price

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 4/1

12:14 pm-11:49 pm

2 stops11h 35m

Panama City NW Florida Beaches

Wed 4/8

6:55 am-12:19 pm

1 stop5h 24m

$284

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 1/21

6:00 am-5:33 pm

2 stops11h 33m

Panama City NW Florida Beaches

Thu 1/29

3:27 pm-10:04 pm

1 stop6h 37m

$284

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 1/9

6:00 am-4:12 pm

2 stops10h 12m

Panama City NW Florida Beaches

Mon 1/12

1:10 pm-11:44 pm

2 stops10h 34m

$319

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 1/9

6:00 am-5:33 pm

2 stops11h 33m

Panama City NW Florida Beaches

Mon 1/12

3:27 pm-10:04 pm

1 stop6h 37m

$406

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Thu 2/26

7:52 pm-12:30 pm

1 stop16h 38m

Panama City NW Florida Beaches

Mon 3/2

1:06 pm-11:49 am

1 stop22h 43m

$407

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 1/28

7:30 am-4:12 pm

2 stops8h 42m

Panama City NW Florida Beaches

Sat 1/31

6:30 am-4:37 pm

2 stops10h 07m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Best time to book a flight from South Dakota to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Panama City

What is the cheapest month to book a flight from South Dakota to Panama City, Florida?

Currently, July is the cheapest month in which you can book a flight from South Dakota to Panama City, Florida (average of $198). Flying from South Dakota to Panama City, Florida in October is currently the most expensive (average of $372). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Dakota to Panama City, Florida?

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from South Dakota?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from South Dakota to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from South Dakota to Panama City, Florida?

    Airlines like American Airlines and United Airlines fly from South Dakota to Panama City, Florida in about 10h 12m. The time it takes to get you to your destination can typically vary by up to 1h 23m. Airlines will cover a distance of 1092 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from South Dakota to Panama City that include hotel bookings?

    Yes. In addition to deals on South Dakota to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Panama City.

  • Can I find deals for business class flights from South Dakota to Panama City?

    Yes. Cheapflights offers flight deals from South Dakota to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Panama City, Florida?

    Currently, July is the cheapest month in which you can book a flight from South Dakota to Panama City, Florida (average of $198). Flying from South Dakota to Panama City, Florida in October is currently the most expensive (average of $372). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for South Dakota to Panama City

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Top 3 airlines flying from South Dakota to Panama City

Discover the top 3 airlines that operate flights from South Dakota to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$254Average$408FlexibilityNo cancel feeOn-time69%
DeltaCheapest$264Average$444FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$274Average$524FlexibilityNo cancel feeOn-time71%

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