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Panama City

$259+ Cheap flights from Sioux Falls to Panama City, FL (FSD - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — ECP
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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Find flight deals from Sioux Falls to Panama City

Cheapest flights from Sioux Falls to Panama City
Explore the most affordable flight options available from Sioux Falls to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amFSD - ECP
1 stop6h 21mAmerican Airlines
Wed 12/103:18 pmECP - FSD
1 stop5h 46mAmerican Airlines
Deal found 10/25$259
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:00 pmFSD - ECP
2 stops7h 37mDelta
Tue 12/95:00 pmECP - FSD
1 stop6h 14mDelta
Deal found 10/26$264
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amFSD - ECP
2 stops10h 03mUnited Airlines
Fri 11/143:00 pmECP - FSD
2 stops29h 23mUnited Airlines
Deal found 10/25$498
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:30 amFSD - ECP
1 stop6h 11mAmerican Airlines
Fri 11/143:19 pmECP - FSD
1 stop25h 20mAmerican Airlines
Deal found 10/26$517
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/41:03 pmFSD - ECP
1 stop6h 13mAmerican Airlines
Fri 11/71:11 pmECP - FSD
1 stop23h 10mAmerican Airlines
Deal found 10/26$603
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/48:57 amFSD - ECP
2 stops12h 52mUnited Airlines
Fri 11/75:00 pmECP - FSD
2 stops27h 23mUnited Airlines
Deal found 10/26$628
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:00 amFSD - ECP
3 stops13h 49mUnited Airlines
Wed 12/103:00 pmECP - FSD
2 stops8h 43mUnited Airlines
Deal found 10/25$661

Cheap flight deals from Sioux Falls to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$259
(American Airlines)

Popular in

December

Cheapest in

January

Average price

$394
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flights.
Search Deals
From Sioux Falls Joe Foss Field to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($3 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Sioux Falls to Panama City that are best for you.

Fly from

Sioux Falls

Fly to

Panama City

Route

Depart

Return

Price

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 12/3

6:00 am-12:21 pm

1 stop6h 21m

Panama City NW Florida Beaches

Wed 12/10

3:18 pm-9:04 pm

1 stop5h 46m

$259

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 12/3

5:05 am-12:47 pm

1 stop7h 42m

Panama City NW Florida Beaches

Wed 12/10

10:00 am-7:40 pm

2 stops9h 40m

$264

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Sat 12/6

5:14 am-3:52 pm

2 stops10h 38m

Panama City NW Florida Beaches

Tue 12/9

5:00 pm-11:14 pm

1 stop6h 14m

$264

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Tue 1/13

5:00 am-12:47 pm

2 stops7h 47m

Panama City NW Florida Beaches

Sat 1/17

7:18 am-3:37 pm

2 stops8h 19m

$281

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Compare providers for flights from Sioux Falls to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Sioux Falls-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Sioux Falls-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Sioux Falls-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Panama City

What is the cheapest month to book a flight from Sioux Falls to Panama City, Florida?

Currently, July is the cheapest month in which you can book a flight from Sioux Falls to Panama City, Florida (average of $198). Flying from Sioux Falls to Panama City, Florida in June is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 27, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Sioux Falls to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,996 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,996 reviews
Delta
7.9
Good
7,996 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
7,996 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,996 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux Falls to Panama City, Florida?

    American Airlines and Delta can get you from Sioux Falls to Panama City, Florida in just under 6h 21m. Your travel time can differ by up to 1h 21m. Sioux Falls and Panama City, Florida are separated by a distance of 1092 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Sioux Falls to Panama City, Florida round-trip?

    United Airlines, at $254, was found to be the cheapest airline from Sioux Falls to Panama City, Florida.Alternate airlines to your destination round-trip include Delta and American Airlines. United Airlines is currently priced 39% below the average price you’ll pay for this route.

  • Can I find deals for flights from Sioux Falls to Panama City that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Panama City.

  • Can I find deals for business class flights from Sioux Falls to Panama City?

    Yes. Cheapflights offers flight deals from Sioux Falls to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Panama City, Florida?

    Currently, July is the cheapest month in which you can book a flight from Sioux Falls to Panama City, Florida (average of $198). Flying from Sioux Falls to Panama City, Florida in June is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Top 3 airlines flying from Sioux Falls to Panama City

Discover the top 3 airlines that operate flights from Sioux Falls to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$254Average$408FlexibilityNo cancel feeOn-time69%
DeltaCheapest$264Average$394FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$274Average$449FlexibilityNo cancel feeOn-time71%

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