$178+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — ECP
Jul 21 — Jul 281
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Panama City
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Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:45 pm
SFO
- ECP
1 stop7h 39m
American Airlines
Tue 11/33:22 pm
ECP
- SFO
1 stop7h 34m
American Airlines
Deal found 6/19![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:40 am
SFO
- ECP
1 stop7h 55m
Southwest
Tue 11/37:35 am
ECP
- SFO
2 stops10h 35m
Southwest
Deal found 6/19![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:45 pm
SFO
- ECP
1 stop7h 45m
Delta
Wed 8/199:27 am
ECP
- SFO
1 stop8h 15m
Delta
Deal found 6/17![Delta logo]()
$368
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:55 pm
SFO
- ECP
2 stops11h 30m
Southwest
Sat 8/2211:45 am
ECP
- SFO
1 stop6h 40m
Southwest
Deal found 6/19![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:45 pm
SFO
- ECP
1 stop7h 45m
Delta
Mon 8/1711:31 am
ECP
- SFO
1 stop7h 44m
Delta
Deal found 6/17![Delta logo]()
$381
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:30 am
SFO
- ECP
1 stop8h 10m
Delta
Tue 8/185:26 pm
ECP
- SFO
1 stop8h 32m
Delta
Deal found 6/17![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:30 am
SFO
- ECP
1 stop8h 10m
Delta
Thu 8/201:53 pm
ECP
- SFO
1 stop7h 46m
Delta
Deal found 6/17![Delta logo]()
$400
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:56 pm
SFO
- ECP
1 stop8h 31m
Delta
Tue 8/185:26 pm
ECP
- SFO
1 stop8h 32m
Delta
Deal found 6/17![Delta logo]()
$406
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:25 am
SFO
- ECP
2 stops9h 45m
Southwest
Sat 7/252:05 pm
ECP
- SFO
1 stop8h 10m
Southwest
Deal found 6/21![Southwest logo]()
$411
Best flights from San Francisco to Panama CityDiscover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:55 pm
SFO
- ECP
2 stops11h 30m
Southwest
Sat 8/228:15 am
ECP
- SFO
2 stops10h 00m
Southwest
Deal found 6/19![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:15 pm
SFO
- ECP
1 stop7h 16m
Delta
Mon 8/109:27 am
ECP
- SFO
1 stop9h 48m
Delta
Deal found 6/17![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:55 pm
SFO
- ECP
2 stops11h 30m
Southwest
Sun 8/304:00 pm
ECP
- SFO
1 stop9h 05m
Southwest
Deal found 6/19![Southwest logo]()
$424
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:59 pm
SFO
- ECP
2 stops11h 43m
Delta
Sun 8/306:51 pm
ECP
- SFO
1 stop7h 07m
Delta
Deal found 6/20![Delta logo]()
$476
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
SFO
- ECP
2 stops11h 45m
Southwest
Sat 8/112:40 pm
ECP
- SFO
2 stops10h 55m
Southwest
Deal found 6/17![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:35 am
SFO
- ECP
1 stop8h 10m
Southwest
Sun 8/307:00 am
ECP
- SFO
2 stops10h 05m
Southwest
Deal found 6/19![Southwest logo]()
$462
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:50 pm
SFO
- ECP
1 stop13h 25m
Southwest
Sun 7/124:20 pm
ECP
- SFO
1 stop9h 55m
Southwest
Deal found 6/16![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:50 pm
SFO
- ECP
1 stop8h 45m
Southwest
Sat 8/112:40 pm
ECP
- SFO
2 stops10h 55m
Southwest
Deal found 6/18![Southwest logo]()
$492
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:40 am
SFO
- ECP
2 stops10h 45m
Southwest
Sat 8/112:40 pm
ECP
- SFO
2 stops10h 55m
Southwest
Deal found 6/18![Southwest logo]()
$497
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:30 am
SFO
- ECP
1 stop7h 50m
Southwest
Sun 7/124:20 pm
ECP
- SFO
1 stop9h 55m
Southwest
Deal found 6/17![Southwest logo]()
$518
Last-minute flights from San Francisco to Panama CityDiscover last-minute flight deals from San Francisco to Panama City. Data last updated June 21, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama City. Data last updated June 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:29 am
SFO
- ECP
1 stop6h 52m
American Airlines
Tue 7/143:13 pm
ECP
- SFO
1 stop9h 15m
American Airlines
Deal found 6/19![American Airlines logo]()
$463
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:30 am
SFO
- ECP
1 stop7h 50m
Southwest
Sun 7/125:40 am
ECP
- SFO
2 stops8h 05m
Southwest
Deal found 6/16![Southwest logo]()
$473
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:50 pm
SFO
- ECP
1 stop13h 25m
Southwest
Sun 7/124:20 pm
ECP
- SFO
1 stop9h 55m
Southwest
Deal found 6/16![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:25 am
SFO
- ECP
2 stops9h 45m
Southwest
Sun 7/267:45 am
ECP
- SFO
1 stop10h 40m
Southwest
Deal found 6/16![Southwest logo]()
$427
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
SFO
- ECP
2 stops11h 45m
Southwest
Sat 8/112:40 pm
ECP
- SFO
2 stops10h 55m
Southwest
Deal found 6/17![Southwest logo]()
$447
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:56 pm
SFO
- ECP
1 stop8h 31m
Delta
Wed 8/199:27 am
ECP
- SFO
1 stop8h 15m
Delta
Deal found 6/17![Delta logo]()
$406
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:56 pm
SFO
- ECP
1 stop8h 31m
Delta
Mon 8/179:27 am
ECP
- SFO
1 stop9h 48m
Delta
Deal found 6/17![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:56 pm
SFO
- ECP
1 stop8h 31m
Delta
Tue 8/189:27 am
ECP
- SFO
2 stops14h 48m
Delta
Deal found 6/17![Delta logo]()
$450
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:56 pm
SFO
- ECP
1 stop8h 31m
Delta
Fri 8/214:10 pm
ECP
- SFO
1 stop7h 50m
Delta
Deal found 6/17![Delta logo]()
$457
One-way flights from San Francisco to Panama CitySearch for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:00 pm
SFO
- ECP
1 stop8h 31m
Delta
Deal found 6/20![Delta logo]()
$178
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:25 am
SFO
- ECP
2 stops9h 45m
Southwest
Deal found 6/17![Southwest logo]()
$183
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:50 pm
SFO
- ECP
1 stop8h 40m
Southwest
Deal found 6/21![Southwest logo]()
$201
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:35 am
SFO
- ECP
1 stop8h 10m
Southwest
Deal found 6/21![Southwest logo]()
$220
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:56 pm
SFO
- ECP
1 stop8h 16m
Delta
Deal found 6/17![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:00 am
SFO
- ECP
2 stops11h 45m
Southwest
Deal found 6/17![Southwest logo]()
$234
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
SFO
- ECP
1 stop8h 12m
Delta
Deal found 6/16![Delta logo]()
$259
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
SFO
- ECP
1 stop7h 25m
Delta
Deal found 6/16![Delta logo]()
$286
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:59 pm
SFO
- ECP
1 stop7h 13m
Delta
Deal found 6/20![Delta logo]()
$300
Find flight deals from San Francisco to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $355 (American Airlines) |
One-way from | $178 (Delta) |
Popular in | December |
Cheapest in | August |
Average price | $570 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 8/20
7:55 pm-9:25 am
2 stops11h 30m
Panama City NW Florida Beaches
Sat 8/22
8:15 am-4:15 pm
2 stops10h 00m
$379
Quickest round-trip
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Mon 8/3
11:15 pm-8:31 am
1 stop7h 16m
Panama City NW Florida Beaches
Mon 8/10
9:27 am-5:15 pm
1 stop9h 48m
$419
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 8/27
7:55 pm-9:25 am
2 stops11h 30m
Panama City NW Florida Beaches
Sun 8/30
4:00 pm-11:05 pm
1 stop9h 05m
$424
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Wed 7/29
6:00 am-7:45 pm
2 stops11h 45m
Panama City NW Florida Beaches
Sat 8/1
12:40 pm-9:35 pm
2 stops10h 55m
$447
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Fri 8/28
5:35 am-3:45 pm
1 stop8h 10m
Panama City NW Florida Beaches
Sun 8/30
7:00 am-3:05 pm
2 stops10h 05m
$462
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Wed 7/8
10:50 pm-2:15 pm
1 stop13h 25m
Panama City NW Florida Beaches
Sun 7/12
4:20 pm-12:15 am
1 stop9h 55m
$472
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 8/27
8:59 pm-10:42 am
2 stops11h 43m
Panama City NW Florida Beaches
Sun 8/30
6:51 pm-11:58 pm
1 stop7h 07m
$476
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 7/30
10:50 pm-9:35 am
1 stop8h 45m
Panama City NW Florida Beaches
Sat 8/1
12:40 pm-9:35 pm
2 stops10h 55m
$492
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Sun 7/26
5:40 am-6:25 pm
2 stops10h 45m
Panama City NW Florida Beaches
Sat 8/1
12:40 pm-9:35 pm
2 stops10h 55m
$497
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Tue 7/7
5:30 am-3:20 pm
1 stop7h 50m
Panama City NW Florida Beaches
Sun 7/12
4:20 pm-12:15 am
1 stop9h 55m
$518
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
SFO-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama City
What is the cheapest month to book a flight from San Francisco to Panama City, Florida?
Currently, August is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $326). Flying from San Francisco to Panama City, Florida in December is currently the most expensive (average of $1,001). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Panama City, Florida?
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated June 21, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
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San Francisco and Panama City flights
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Top 4 airlines flying from San Francisco to Panama City
Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$300 | Average$473 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$576 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$342 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$394 | Average$494 | FlexibilityNo cancel fee | On-time63% |