What are the cheapest airlines to fly from San Francisco to Panama City, Florida one-way?

To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $159. Delta flights start at $209 while deals on United Airlines start at $240 one-way.

What is the cheapest day to fly from San Francisco to Panama City, Florida?

Travelers seeking maximum savings on their San Francisco to Panama City, Florida flight should consider departing on Saturday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

What are the most popular airlines that fly from San Francisco to Panama City, Florida?

When booking a flight from San Francisco to Panama City, Florida, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from San Francisco to Panama City, Florida?

Friday is generally a great day to depart. Flying on this day could help you save up to 37%.

How far in advance should I book a flight from San Francisco to Panama City, Florida?

To save on the cost of your flight from San Francisco to Panama City, Florida, book at least 39 days before your planned departure. Booking around this time can save you about 190% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $594 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $901.

What is the cheapest month to fly from San Francisco to Panama City, Florida?

Due to multiple factors, expect to potentially pay more when booking in January. For low rates, August can be a great choice for travel to Panama City, Florida. Flights to Panama City, Florida from San Francisco in August are about $502 on average during August, but can be found for as low as $310.

Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Francisco to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.

Can I find deals for business class flights from San Francisco to Panama City?

Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$159+ Flights from San Francisco to Panama City, FL

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from San Francisco to Panama City NW Florida Beaches are usually found in August or March, booked 74 days in advance, depart on a Saturday or Tuesday and return on a Tuesday

Cheap flight deals from San Francisco to Panama City

Round-trip from	$332 (Delta)
One-way from	$159 (American Airlines)
Popular in	January
Cheapest in	August
Average price	$536

From San Francisco to Panama City NW Florida Beaches

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One-way flight from San Francisco to Panama City NW Florida Beaches

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Highest demand for flights based on searches. 10% potential increase in price ($57 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Find flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Wed 8/271:41 pmSFO - ECP

1 stop7h 25mDelta

Sun 8/316:00 amECP - SFO

1 stop7h 45mDelta

Deal found 6/28

$332

Wed 8/2710:16 amSFO - ECP

2 stops9h 41mAmerican Airlines

Sun 8/316:35 amECP - SFO

1 stop8h 25mAmerican Airlines

Deal found 6/28

$352

Fri 9/199:05 pmSFO - ECP

1 stop11h 15mSouthwest

Mon 9/229:50 amECP - SFO

2 stops7h 55mSouthwest

Deal found 6/27

$393

Tue 8/2612:43 amSFO - ECP

1 stop7h 10mUnited Airlines

Sun 8/316:30 amECP - SFO

1 stop10h 05mUnited Airlines

Deal found 6/28

$432

Best flights from San Francisco to Panama City
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 30, 2025.

Wed 8/271:41 pmSFO - ECP

1 stop7h 25mDelta

Sun 8/316:00 amECP - SFO

1 stop7h 45mDelta

Deal found 6/28

$332

Wed 8/2710:16 amSFO - ECP

2 stops9h 41mAmerican Airlines

Sun 8/316:35 amECP - SFO

1 stop8h 25mAmerican Airlines

Deal found 6/28

$352

Fri 9/199:05 pmSFO - ECP

1 stop11h 15mSouthwest

Mon 9/229:50 amECP - SFO

2 stops7h 55mSouthwest

Deal found 6/27

$393

Tue 8/2612:43 amSFO - ECP

1 stop7h 10mUnited Airlines

Sun 8/316:30 amECP - SFO

1 stop10h 05mUnited Airlines

Deal found 6/28

$432

Last-minute flights from San Francisco to Panama City
Discover last-minute flight deals from San Francisco to Panama City. Data last updated June 30, 2025 and is based on user searches.

Tue 7/812:30 amSFO - ECP

1 stop7h 26mUnited Airlines

Sun 7/135:02 pmECP - SFO

1 stop6h 59mUnited Airlines

Deal found 6/30

$992

Tue 7/812:50 amSFO - ECP

2 stops11h 07mDelta

Sun 7/1311:17 amECP - SFO

1 stop8h 07mDelta

Deal found 6/30

$1,078

Wed 7/911:59 pmSFO - ECP

1 stop16h 52mAmerican Airlines

Sun 7/139:47 amECP - SFO

1 stop10h 56mAmerican Airlines

Deal found 6/30

$793

Wed 7/95:25 amSFO - ECP

2 stops9h 10mSouthwest

Sun 7/1311:35 amECP - SFO

2 stops10h 10mSouthwest

Deal found 6/30

$857

Sun 7/1312:30 amSFO - ECP

1 stop7h 26mUnited Airlines

Fri 7/185:02 pmECP - SFO

1 stop8h 57mUnited Airlines

Deal found 6/29

$517

Wed 7/1611:39 amSFO - ECP

1 stop7h 54mDelta

Tue 7/221:12 pmECP - SFO

1 stop10h 15mDelta

Deal found 6/29

$497

Wed 7/1610:03 amSFO - ECP

2 stops10h 00mAmerican Airlines

Tue 7/225:17 pmECP - SFO

1 stop8h 51mAmerican Airlines

Deal found 6/29

$502

Wed 7/165:25 amSFO - ECP

2 stops10h 20mSouthwest

Tue 7/224:05 pmECP - SFO

2 stops9h 20mSouthwest

Deal found 6/29

$527

One-way flights from San Francisco to Panama City
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated June 30, 2025.

Mon 8/411:59 pmSFO - ECP

1 stop9h 17mAmerican Airlines

Deal found 6/27

$159

Thu 7/319:35 pmSFO - ECP

1 stop8h 58mDelta

Deal found 6/29

$209

Sun 8/312:30 amSFO - ECP

1 stop7h 26mUnited Airlines

Deal found 6/27

$240

Thu 7/3112:10 pmSFO - ECP

2 stops8h 50mSouthwest

Deal found 6/29

$244

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Wed 8/27

1:41 pm-11:06 pm

1 stop7h 25m

Panama City NW Florida Beaches

Sun 8/31

6:00 am-11:45 am

1 stop7h 45m

$332

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Wed 8/27

10:16 am-9:57 pm

2 stops9h 41m

Panama City NW Florida Beaches

Sun 8/31

6:35 am-1:00 pm

1 stop8h 25m

$352

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Fri 9/19

9:05 pm-10:20 am

1 stop11h 15m

Panama City NW Florida Beaches

Mon 9/22

9:50 am-3:45 pm

2 stops7h 55m

$393

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 8/26

12:43 am-9:53 am

1 stop7h 10m

Panama City NW Florida Beaches

Sun 8/31

6:30 am-2:35 pm

1 stop10h 05m

$432

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Mon 8/4

11:59 pm-11:16 am

1 stop9h 17m

$159

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Thu 7/31

9:35 pm-8:33 am

1 stop8h 58m

$209

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Sun 8/3

12:30 am-9:56 am

1 stop7h 26m

$240

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Thu 7/31

12:10 pm-11:00 pm

2 stops8h 50m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/27

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City, Florida?

To ensure you get the cheapest price possible for a flight from San Francisco to Panama City, Florida, you should look to book at least 74 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $346). Flying from San Francisco to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to ECP?

A simple way to save on the total cost of your ticket is to fly from San Francisco to Panama City, Florida in the afternoon. If you’re flexible enough to do this you can expect to save up to 39% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Southwest

8.0

Very good

4,278 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Delta

8.0

Very good

7,973 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

United Airlines

7.4

Good

8,852 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

What are the cheapest airlines flying from San Francisco to Panama City, Florida round-trip?
According to our current data, Delta ($332), American Airlines ($352), and Southwest ($393) offers the cheapest pricing from San Francisco to Panama City, Florida. Delta is priced at 33% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from San Francisco to Panama City, Florida one-way?
To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $159. Delta flights start at $209 while deals on United Airlines start at $240 one-way.
Can I find deals for flights from San Francisco to Panama City that include hotel bookings?
Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.
Can I find deals for business class flights from San Francisco to Panama City?
Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $346). Flying from San Francisco to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Mexico Beach

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Top 4 airlines flying from San Francisco to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$306	Average$423	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$316	Average$515	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$386	Average$521	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$416	Average$536	FlexibilityNo cancel fee	On-time63%

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$159+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from San Francisco to Panama City NW Florida Beaches are usually found in August or March, booked 74 days in advance, depart on a Saturday or Tuesday and return on a Tuesday

Cheap flight deals from San Francisco to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Panama City. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

What is the cheapest time of day to fly from SFO to ECP?

Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from San Francisco to Panama City, Florida round-trip?

What are the cheapest airlines to fly from San Francisco to Panama City, Florida one-way?

Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

How can I find direct flights from San Francisco to Panama City?

Can I find deals for business class flights from San Francisco to Panama City?

What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

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Alternative routes for San Francisco to Panama City

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Top 4 airlines flying from San Francisco to Panama City

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Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.