$151+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — ECP
Aug 17 — Aug 241
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Panama City
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Best
Last-minute
One-way
Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:45 pm
SFO
- ECP
1 stop7h 45m
Delta
Mon 8/311:53 pm
ECP
- SFO
1 stop7h 46m
Delta
Deal found 7/14![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:05 pm
SFO
- ECP
1 stop8h 45m
Southwest
Mon 8/311:30 pm
ECP
- SFO
1 stop10h 25m
Southwest
Deal found 7/14![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:15 am
SFO
- ECP
1 stop8h 20m
Southwest
Mon 8/316:00 am
ECP
- SFO
2 stops7h 55m
Southwest
Deal found 7/15![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:40 pm
SFO
- ECP
1 stop14h 05m
Southwest
Wed 9/3010:30 am
ECP
- SFO
2 stops8h 50m
Southwest
Deal found 7/16![Southwest logo]()
$341
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:35 am
SFO
- ECP
2 stops9h 55m
Southwest
Thu 12/38:00 am
ECP
- SFO
1 stop9h 45m
Southwest
Deal found 7/17![Southwest logo]()
$374
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:45 am
SFO
- ECP
1 stop8h 19m
United Airlines
Wed 8/196:30 am
ECP
- SFO
1 stop7h 44m
United Airlines
Deal found 7/16![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 pm
SFO
- ECP
1 stop7h 55m
Southwest
Mon 8/311:30 pm
ECP
- SFO
1 stop10h 25m
Southwest
Deal found 7/14![Southwest logo]()
$384
Best flights from San Francisco to Panama CityDiscover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:35 pm
SFO
- ECP
1 stop6h 41m
Delta
Wed 9/305:30 pm
ECP
- SFO
1 stop8h 27m
Delta
Deal found 7/16![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
SFO
- ECP
2 stops13h 00m
Southwest
Wed 9/309:10 am
ECP
- SFO
2 stops9h 45m
Southwest
Deal found 7/16![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:00 am
SFO
- ECP
1 stop9h 23m
United Airlines
Tue 11/39:05 am
ECP
- SFO
1 stop10h 03m
United Airlines
Deal found 7/17![United Airlines logo]()
$502
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2511:45 pm
SFO
- ECP
1 stop8h 51m
Delta
Sat 10/315:30 pm
ECP
- SFO
1 stop7h 21m
Delta
Deal found 7/16![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:40 pm
SFO
- ECP
1 stop8h 10m
Southwest
Mon 8/316:00 am
ECP
- SFO
2 stops7h 55m
Southwest
Deal found 7/15![Southwest logo]()
$384
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:35 am
SFO
- ECP
2 stops10h 15m
Southwest
Thu 8/204:25 pm
ECP
- SFO
2 stops8h 40m
Southwest
Deal found 7/13![Southwest logo]()
$430
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/110:45 pm
SFO
- ECP
1 stop7h 27m
Delta
Mon 8/106:51 pm
ECP
- SFO
1 stop7h 07m
Delta
Deal found 7/14![Delta logo]()
$569
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:50 pm
SFO
- ECP
1 stop8h 45m
Southwest
Mon 10/121:50 pm
ECP
- SFO
2 stops10h 15m
Southwest
Deal found 7/15![Southwest logo]()
$563
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:00 pm
SFO
- ECP
1 stop8h 31m
Delta
Sun 8/166:51 pm
ECP
- SFO
1 stop7h 07m
Delta
Deal found 7/18![Delta logo]()
$588
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2510:30 pm
SFO
- ECP
1 stop7h 50m
Delta
Mon 1/44:10 pm
ECP
- SFO
1 stop10h 05m
Delta
Deal found 7/13![Delta logo]()
$619
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:59 pm
SFO
- ECP
1 stop18h 28m
Delta
Thu 12/244:10 pm
ECP
- SFO
1 stop7h 25m
Delta
Deal found 7/17![Delta logo]()
$640
Last-minute flights from San Francisco to Panama CityDiscover last-minute flight deals from San Francisco to Panama City. Data last updated July 18, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama City. Data last updated July 18, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:05 pm
SFO
- ECP
1 stop12h 00m
Southwest
Thu 8/134:25 pm
ECP
- SFO
2 stops8h 40m
Southwest
Deal found 7/16![Southwest logo]()
$390
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:45 am
SFO
- ECP
1 stop8h 19m
United Airlines
Wed 8/196:30 am
ECP
- SFO
1 stop7h 44m
United Airlines
Deal found 7/16![United Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:00 pm
SFO
- ECP
1 stop8h 31m
Delta
Tue 9/11:53 pm
ECP
- SFO
1 stop7h 46m
Delta
Deal found 7/14![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:15 am
SFO
- ECP
1 stop8h 20m
Southwest
Mon 8/316:00 am
ECP
- SFO
2 stops7h 55m
Southwest
Deal found 7/15![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 pm
SFO
- ECP
1 stop7h 55m
Southwest
Mon 8/311:30 pm
ECP
- SFO
1 stop10h 25m
Southwest
Deal found 7/14![Southwest logo]()
$384
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:09 pm
SFO
- ECP
1 stop17h 58m
Delta
Tue 9/11:53 pm
ECP
- SFO
1 stop7h 46m
Delta
Deal found 7/14![Delta logo]()
$402
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:40 am
SFO
- ECP
1 stop7h 55m
Southwest
Mon 8/316:00 am
ECP
- SFO
2 stops7h 55m
Southwest
Deal found 7/14![Southwest logo]()
$306
One-way flights from San Francisco to Panama CitySearch for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:35 pm
SFO
- ECP
1 stop6h 41m
Delta
Deal found 7/15![Delta logo]()
$151
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:50 am
SFO
- ECP
2 stops9h 20m
Southwest
Deal found 7/15![Southwest logo]()
$156
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:45 am
SFO
- ECP
1 stop8h 21m
United Airlines
Deal found 7/15![United Airlines logo]()
$206
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:00 pm
SFO
- ECP
1 stop8h 18m
Delta
Deal found 7/15![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:40 pm
SFO
- ECP
2 stops12h 15m
Southwest
Deal found 7/15![Southwest logo]()
$234
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am
SFO
- ECP
2 stops11h 08m
Delta
Deal found 7/15![Delta logo]()
$246
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:45 am
SFO
- ECP
1 stop8h 19m
United Airlines
Deal found 7/15![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:40 am
SFO
- ECP
2 stops11h 30m
Southwest
Deal found 7/13![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:30 pm
SFO
- ECP
2 stops15h 46m
Delta
Deal found 7/15![Delta logo]()
$282
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:56 pm
SFO
- ECP
1 stop8h 16m
Delta
Deal found 7/13![Delta logo]()
$289
Find flight deals from San Francisco to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $301 (Delta) |
One-way from | $151 (Delta) |
Popular in | December |
Cheapest in | January |
Average price | $456 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 9/24
11:35 pm-8:16 am
1 stop6h 41m
Panama City NW Florida Beaches
Wed 9/30
5:30 pm-11:57 pm
1 stop8h 27m
$301
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 9/24
6:00 am-9:00 pm
2 stops13h 00m
Panama City NW Florida Beaches
Wed 9/30
9:10 am-4:55 pm
2 stops9h 45m
$372
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Sun 10/25
11:45 pm-10:36 am
1 stop8h 51m
Panama City NW Florida Beaches
Sat 10/31
5:30 pm-10:51 pm
1 stop7h 21m
$379
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Fri 8/21
11:40 pm-9:50 am
1 stop8h 10m
Panama City NW Florida Beaches
Mon 8/31
6:00 am-11:55 am
2 stops7h 55m
$384
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Sun 8/16
9:35 am-9:50 pm
2 stops10h 15m
Panama City NW Florida Beaches
Thu 8/20
4:25 pm-11:05 pm
2 stops8h 40m
$430
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Sat 10/31
5:00 am-4:23 pm
1 stop9h 23m
Panama City NW Florida Beaches
Tue 11/3
9:05 am-5:08 pm
1 stop10h 03m
$502
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 10/8
10:50 pm-9:35 am
1 stop8h 45m
Panama City NW Florida Beaches
Mon 10/12
1:50 pm-10:05 pm
2 stops10h 15m
$563
Quickest round-trip
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Sat 8/1
10:45 pm-8:12 am
1 stop7h 27m
Panama City NW Florida Beaches
Mon 8/10
6:51 pm-11:58 pm
1 stop7h 07m
$569
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Mon 8/10
10:00 pm-8:31 am
1 stop8h 31m
Panama City NW Florida Beaches
Sun 8/16
6:51 pm-11:58 pm
1 stop7h 07m
$588
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Fri 12/25
10:30 pm-8:20 am
1 stop7h 50m
Panama City NW Florida Beaches
Mon 1/4
4:10 pm-12:15 am
1 stop10h 05m
$619
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
SFO-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama City
What is the cheapest month to book a flight from San Francisco to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $342). Flying from San Francisco to Panama City, Florida in December is currently the most expensive (average of $1,001). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Panama City, Florida?
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 18, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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Find flights from San Francisco to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Panama City flights
Browse other San Francisco and Panama City flight options. Last updated on July 18, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on July 18, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Panama City
Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$324 | Average$492 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$342 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$378 | Average$494 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$425 | Average$606 | FlexibilityNo cancel fee | On-time71% |