What are the cheapest airlines to fly from San Francisco to Panama City, Florida one-way?

To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $259. Southwest flights start at $304 while deals on United Airlines start at $424 one-way.

What is the cheapest day to fly from San Francisco to Panama City, Florida?

Travelers seeking maximum savings on their San Francisco to Panama City, Florida flight should consider departing on Saturday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from San Francisco to Panama City, Florida?

When booking a flight from San Francisco to Panama City, Florida, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from San Francisco to Panama City, Florida?

Friday is generally a great day to depart. Flying on this day could help you save up to 37%.

How far in advance should I book a flight from San Francisco to Panama City, Florida?

To save on the cost of your flight from San Francisco to Panama City, Florida, book at least 39 days before your planned departure. Booking around this time can save you about 190% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $594 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $901.

What is the cheapest month to fly from San Francisco to Panama City, Florida?

Due to multiple factors, expect to potentially pay more when booking in January. For low rates, March can be a great choice for travel to Panama City, Florida. Flights to Panama City, Florida from San Francisco in March are about $503 on average during March, but can be found for as low as $342.

Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Francisco to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.

Can I find deals for business class flights from San Francisco to Panama City?

Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$259+ Flights from San Francisco to Panama City, FL

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from San Francisco to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from San Francisco to Panama City NW Florida Beaches are usually found in March or August, booked 74 days in advance, depart on a Saturday or Tuesday and return on a Tuesday

Cheap flight deals from San Francisco to Panama City

Round-trip from	$317 (United Airlines)
One-way from	$259 (American Airlines)
Popular in	January
Cheapest in	March
Average price	$521

From San Francisco to Panama City NW Florida Beaches

Search Deals

One-way flight from San Francisco to Panama City NW Florida Beaches

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($56 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in June 2025

Search Deals

Find flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2025.

Mon 8/1112:30 amSFO - ECP

1 stop7h 26mUnited Airlines

Tue 8/196:30 amECP - SFO

1 stop7h 45mUnited Airlines

Deal found 6/16

$317

Tue 8/129:12 amSFO - ECP

2 stops10h 45mAmerican Airlines

Tue 8/1912:06 pmECP - SFO

1 stop9h 40mAmerican Airlines

Deal found 6/16

$322

Tue 8/56:15 amSFO - ECP

1 stop7h 52mDelta

Tue 8/121:53 pmECP - SFO

1 stop8h 32mDelta

Deal found 6/16

$327

Tue 8/195:15 amSFO - ECP

2 stops11h 35mSouthwest

Tue 8/267:00 amECP - SFO

2 stops10h 55mSouthwest

Deal found 6/16

$347

Best flights from San Francisco to Panama City
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2025.

Mon 8/1112:30 amSFO - ECP

1 stop7h 26mUnited Airlines

Tue 8/196:30 amECP - SFO

1 stop7h 45mUnited Airlines

Deal found 6/16

$317

Tue 8/129:12 amSFO - ECP

2 stops10h 45mAmerican Airlines

Tue 8/1912:06 pmECP - SFO

1 stop9h 40mAmerican Airlines

Deal found 6/16

$322

Tue 8/56:15 amSFO - ECP

1 stop7h 52mDelta

Wed 8/135:02 pmECP - SFO

1 stop7h 47mDelta

Deal found 6/16

$327

Tue 8/195:15 amSFO - ECP

2 stops11h 35mSouthwest

Tue 8/267:00 amECP - SFO

2 stops10h 55mSouthwest

Deal found 6/16

$347

Last-minute flights from San Francisco to Panama City
Discover last-minute flight deals from San Francisco to Panama City. Data last updated June 17, 2025 and is based on user searches.

Wed 6/2512:24 amSFO - ECP

1 stop7h 32mUnited Airlines

Fri 7/46:30 amECP - SFO

1 stop7h 46mUnited Airlines

Deal found 6/16

$652

Thu 6/2612:59 amSFO - ECP

1 stop8h 17mAmerican Airlines

Mon 6/307:19 pmECP - SFO

1 stop6h 53mAmerican Airlines

Deal found 6/15

$597

Fri 6/277:30 amSFO - ECP

1 stop6h 40mDelta

Fri 7/47:25 amECP - SFO

1 stop8h 48mDelta

Deal found 6/16

$602

Fri 6/275:30 amSFO - ECP

1 stop8h 55mSouthwest

Thu 7/37:00 amECP - SFO

1 stop9h 15mSouthwest

Deal found 6/16

$682

Mon 7/711:59 pmSFO - ECP

1 stop7h 57mUnited Airlines

Tue 7/2211:10 amECP - SFO

1 stop8h 35mUnited Airlines

Deal found 6/14

$428

Tue 7/811:26 amSFO - ECP

2 stops8h 37mAmerican Airlines

Fri 7/115:17 pmECP - SFO

1 stop8h 51mAmerican Airlines

Deal found 6/16

$433

Tue 7/1510:45 pmSFO - ECP

1 stop8h 00mSouthwest

Sat 7/197:35 amECP - SFO

1 stop9h 25mSouthwest

Deal found 6/14

$417

One-way flights from San Francisco to Panama City
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated June 17, 2025.

Thu 7/311:25 pmSFO - ECP

1 stop10h 38mAmerican Airlines

Deal found 6/15

$259

Thu 7/312:10 pmSFO - ECP

2 stops8h 50mSouthwest

Deal found 6/16

$304

Fri 6/279:00 amSFO - ECP

1 stop7h 55mUnited Airlines

Deal found 6/16

$424

Fri 6/2712:52 amSFO - ECP

2 stops11h 10mDelta

Deal found 6/16

$1,188

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Mon 8/11

12:30 am-9:56 am

1 stop7h 26m

Panama City NW Florida Beaches

Tue 8/19

6:30 am-12:15 pm

1 stop7h 45m

$317

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 8/12

9:12 am-9:57 pm

2 stops10h 45m

Panama City NW Florida Beaches

Tue 8/19

12:06 pm-7:46 pm

1 stop9h 40m

$322

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 8/5

6:15 am-4:07 pm

1 stop7h 52m

Panama City NW Florida Beaches

Wed 8/13

5:02 pm-10:49 pm

1 stop7h 47m

$327

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 8/19

5:15 am-6:50 pm

2 stops11h 35m

Panama City NW Florida Beaches

Tue 8/26

7:00 am-3:55 pm

2 stops10h 55m

$347

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Thu 7/3

11:25 pm-12:03 pm

1 stop10h 38m

$259

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Thu 7/3

12:10 pm-11:00 pm

2 stops8h 50m

$304

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Fri 6/27

9:00 am-6:55 pm

1 stop7h 55m

$424

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Fri 6/27

12:52 am-2:02 pm

2 stops11h 10m

$1,188

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/15

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City, Florida?

To ensure you get the cheapest price possible for a flight from San Francisco to Panama City, Florida, you should look to book at least 74 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $346). Flying from San Francisco to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to ECP?

A simple way to save on the total cost of your ticket is to fly from San Francisco to Panama City, Florida in the afternoon. If you’re flexible enough to do this you can expect to save up to 39% on your trip compared to booking a flight in the evening.

Rainfall in Panama City by month

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from San Francisco to Panama City to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Southwest

8.0

Very good

4,279 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Delta

8.0

Very good

7,965 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

United Airlines

7.4

Good

8,809 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

What are the cheapest airlines flying from San Francisco to Panama City, Florida round-trip?
According to our current data, United Airlines ($317), American Airlines ($322), and Delta ($327) offers the cheapest pricing from San Francisco to Panama City, Florida. United Airlines is priced at 36% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from San Francisco to Panama City, Florida one-way?
To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $259. Southwest flights start at $304 while deals on United Airlines start at $424 one-way.
Can I find deals for flights from San Francisco to Panama City that include hotel bookings?
Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.
Can I find deals for business class flights from San Francisco to Panama City?
Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $346). Flying from San Francisco to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from San Francisco to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$306	Average$430	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$342	Average$516	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$386	Average$509	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$416	Average$536	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$259+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from San Francisco to Panama City NW Florida Beaches are usually found in March or August, booked 74 days in advance, depart on a Saturday or Tuesday and return on a Tuesday

Cheap flight deals from San Francisco to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2025.

Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Panama City. Price data was last updated on June 13, 2025.

What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

What is the cheapest time of day to fly from SFO to ECP?

Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 17, 2025.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from San Francisco to Panama City to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from San Francisco to Panama City, Florida round-trip?

What are the cheapest airlines to fly from San Francisco to Panama City, Florida one-way?

Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

How can I find direct flights from San Francisco to Panama City?

Can I find deals for business class flights from San Francisco to Panama City?

What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

Traveling to a place near San Francisco?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from San Francisco to Panama City

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2025.