San Francisco

$279+ Cheap flights from Panama City, FL to San Francisco (ECP - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SFO
May 20 — May 271
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Cheap flight deals from Panama City to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 15, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$380
(Delta)

One-way from

$279
(Southwest)

Popular in

May

Cheapest in

April

Average price

$641
Provider with most accurate pricing for Panama City NW Florida Beaches-San Francisco flight deals.
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-San Francisco flights.
From Panama City NW Florida Beaches to San Francisco
One-way flight from Panama City NW Florida Beaches to San Francisco
Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Average for round-trip flights in May 2025

Find flight deals from Panama City to San Francisco

Cheapest flights from Panama City to San Francisco
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2025.

This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/305:05 pmECP - SFO
1 stop7h 44mDelta
Mon 8/47:30 amSFO - ECP
1 stop6h 50mDelta
Deal found 5/14$380
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/277:19 pmECP - SFO
1 stop6h 53mAmerican Airlines
Mon 6/305:42 amSFO - ECP
1 stop9h 05mAmerican Airlines
Deal found 5/14$417
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/275:50 amECP - SFO
2 stops9h 15mSouthwest
Mon 6/3010:45 pmSFO - ECP
1 stop8h 00mSouthwest
Deal found 5/14$492
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/275:02 pmECP - SFO
1 stop8h 57mUnited Airlines
Sun 6/2912:30 amSFO - ECP
1 stop7h 26mUnited Airlines
Deal found 5/14$517

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2025.
Use the filters below to find and compare flights from Panama City to San Francisco that are best for you.

Fly from

Panama City

Fly to

San Francisco

Route

Depart

Return

Price

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Wed 7/30

5:05 pm-10:49 pm

1 stop7h 44m

San Francisco

Mon 8/4

7:30 am-4:20 pm

1 stop6h 50m

$380

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Fri 6/27

7:19 pm-12:12 am

1 stop6h 53m

San Francisco

Mon 6/30

5:42 am-4:47 pm

1 stop9h 05m

$417

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Fri 6/27

5:50 am-1:05 pm

2 stops9h 15m

San Francisco

Mon 6/30

10:45 pm-8:45 am

1 stop8h 00m

$492

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Fri 6/27

5:02 pm-11:59 pm

1 stop8h 57m

San Francisco

Sun 6/29

12:30 am-9:56 am

1 stop7h 26m

$517

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Sun 11/9

7:30 am-3:05 pm

1 stop9h 35m

$279

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Mon 5/26

6:47 am-1:27 pm

1 stop8h 40m

$424

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Mon 5/26

6:30 am-7:48 pm

3 stops15h 18m

$1,271

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/14

Compare providers for flights from Panama City to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-San Francisco flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Francisco

What is the cheapest month to book a flight from Panama City, Florida to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to San Francisco (average of $276). Flying from Panama City, Florida to San Francisco in June is currently the most expensive (average of $378). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SFO?

Find hourly flight availability from Panama City to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 15, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 23% on flights from Panama City, Florida to San Francisco by exploring options for tickets in the evening.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 15, 2025.

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.6

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.6

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
8.0
Very good

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.6

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.6

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.6

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Panama City, Florida to San Francisco round-trip?

    Currently priced at $380, Delta will fly you from Panama City, Florida to San Francisco and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Southwest - these airlines can fly you to your destination from $417 and $492, respectively. Delta is priced at 10% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Panama City, Florida to San Francisco one-way?

    $279 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $424 and $1,271, respectively.

  • Can I find deals for flights from Panama City to San Francisco that include hotel bookings?

    Yes. In addition to deals on Panama City to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Francisco.

  • Can I find deals for business class flights from Panama City to San Francisco?

    Yes. Cheapflights offers flight deals from Panama City to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to San Francisco (average of $276). Flying from Panama City, Florida to San Francisco in June is currently the most expensive (average of $378). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Livermore
South San Francisco
Turlock
Watsonville
Manteca
Fairfield
Newark
Richmond
Hollister
Milpitas
Antioch
Hayward
Alameda
Sunnyvale
Daly City
Campbell
Union City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Panama City to San Francisco

Discover the top 3 airlines that operate flights from Panama City to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$296Average$441FlexibilityNo cancel feeOn-time63%
DeltaCheapest$311Average$397FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$360Average$396FlexibilityNo cancel feeOn-time71%

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