$131+ Cheap flights from Panama City, FL to San Francisco (ECP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SFO
Aug 8 — Aug 151
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to San Francisco
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Cheapest flights from Panama City to San FranciscoExplore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 pm
ECP
- SFO
1 stop8h 27m
Delta
Mon 10/2611:45 pm
SFO
- ECP
1 stop6h 29m
Delta
Deal found 7/8![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:45 am
ECP
- SFO
1 stop6h 40m
Southwest
Tue 9/228:40 am
SFO
- ECP
2 stops9h 50m
Southwest
Deal found 7/9![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:35 pm
ECP
- SFO
1 stop9h 22m
Delta
Tue 9/222:00 pm
SFO
- ECP
1 stop7h 05m
Delta
Deal found 7/9![Delta logo]()
$296
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:25 pm
ECP
- SFO
2 stops8h 40m
Southwest
Mon 8/175:35 am
SFO
- ECP
1 stop8h 10m
Southwest
Deal found 7/6![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:17 pm
ECP
- SFO
1 stop9h 13m
American Airlines
Thu 9/246:12 am
SFO
- ECP
1 stop9h 20m
American Airlines
Deal found 7/7![American Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:46 pm
ECP
- SFO
1 stop8h 12m
Delta
Thu 9/2410:00 pm
SFO
- ECP
1 stop8h 16m
Delta
Deal found 7/9![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:20 am
ECP
- SFO
1 stop9h 55m
Southwest
Tue 9/226:35 am
SFO
- ECP
2 stops10h 10m
Southwest
Deal found 7/9![Southwest logo]()
$324
Best flights from Panama City to San FranciscoDiscover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
Discover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 pm
ECP
- SFO
1 stop8h 27m
Delta
Mon 10/2611:45 pm
SFO
- ECP
1 stop6h 29m
Delta
Deal found 7/9![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am
ECP
- SFO
1 stop9h 45m
Southwest
Sun 12/66:50 am
SFO
- ECP
2 stops11h 40m
Southwest
Deal found 7/6![Southwest logo]()
$422
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:27 pm
ECP
- SFO
2 stops20h 49m
United Airlines
Fri 9/2512:45 am
SFO
- ECP
1 stop8h 21m
United Airlines
Deal found 7/8![United Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:35 pm
ECP
- SFO
1 stop9h 22m
Delta
Tue 9/222:00 pm
SFO
- ECP
1 stop7h 05m
Delta
Deal found 7/9![Delta logo]()
$296
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:46 pm
ECP
- SFO
1 stop8h 12m
Delta
Thu 9/2410:00 pm
SFO
- ECP
1 stop8h 16m
Delta
Deal found 7/9![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/164:00 pm
ECP
- SFO
1 stop9h 05m
Southwest
Wed 8/266:50 am
SFO
- ECP
2 stops9h 20m
Southwest
Deal found 7/5![Southwest logo]()
$434
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:30 pm
ECP
- SFO
1 stop8h 27m
Delta
Sun 10/119:30 pm
SFO
- ECP
1 stop8h 44m
Delta
Deal found 7/7![Delta logo]()
$429
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:10 pm
ECP
- SFO
1 stop8h 41m
Delta
Mon 12/76:00 am
SFO
- ECP
1 stop7h 15m
Delta
Deal found 7/6![Delta logo]()
$457
Last-minute flights from Panama City to San FranciscoDiscover last-minute flight deals from Panama City to San Francisco. Data last updated July 9, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Francisco. Data last updated July 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:56 pm
ECP
- SFO
1 stop7h 47m
American Airlines
Sat 8/2911:40 pm
SFO
- ECP
1 stop8h 59m
American Airlines
Deal found 7/8![American Airlines logo]()
$416
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:53 pm
ECP
- SFO
1 stop7h 46m
Delta
Thu 8/1310:00 pm
SFO
- ECP
1 stop8h 31m
Delta
Deal found 7/8![Delta logo]()
$342
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:53 pm
ECP
- SFO
1 stop10h 07m
Delta
Wed 8/196:00 am
SFO
- ECP
1 stop8h 02m
Delta
Deal found 7/9![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:10 am
ECP
- SFO
2 stops10h 10m
Southwest
Wed 8/196:50 am
SFO
- ECP
2 stops9h 55m
Southwest
Deal found 7/9![Southwest logo]()
$341
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:25 pm
ECP
- SFO
2 stops8h 40m
Southwest
Mon 8/175:35 am
SFO
- ECP
1 stop8h 10m
Southwest
Deal found 7/6![Southwest logo]()
$300
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/164:00 pm
ECP
- SFO
1 stop9h 05m
Southwest
Wed 8/266:50 am
SFO
- ECP
2 stops9h 20m
Southwest
Deal found 7/5![Southwest logo]()
$434
One-way flights from Panama City to San FranciscoSearch for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
Search for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:10 pm
ECP
- SFO
1 stop10h 05m
Delta
Deal found 7/7![Delta logo]()
$131
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:35 am
ECP
- SFO
2 stops10h 35m
Southwest
Deal found 7/7![Southwest logo]()
$136
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:20 pm
ECP
- SFO
1 stop7h 15m
Delta
Deal found 7/8![Delta logo]()
$166
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:55 pm
ECP
- SFO
1 stop7h 44m
United Airlines
Deal found 7/5![United Airlines logo]()
$201
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:55 pm
ECP
- SFO
1 stop8h 52m
United Airlines
Deal found 7/6![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:00 am
ECP
- SFO
2 stops10h 00m
Southwest
Deal found 7/6![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:00 am
ECP
- SFO
2 stops10h 05m
Southwest
Deal found 7/6![Southwest logo]()
$244
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:47 pm
ECP
- SFO
1 stop10h 02m
Delta
Deal found 7/8![Delta logo]()
$259
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:25 pm
ECP
- SFO
2 stops9h 50m
Southwest
Deal found 7/8![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:03 pm
ECP
- SFO
1 stop7h 46m
Delta
Deal found 7/8![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:48 pm
ECP
- SFO
1 stop7h 48m
Delta
Deal found 7/8![Delta logo]()
$300
Find flight deals from Panama City to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $261 (Delta) |
One-way from | $131 (Delta) |
Popular in | February |
Cheapest in | August |
Average price | $501 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from Panama City to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Sat 9/19
5:30 pm-11:57 pm
1 stop8h 27m
San Francisco
Mon 10/26
11:45 pm-8:14 am
1 stop6h 29m
$261
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Fri 9/18
4:35 pm-11:57 pm
1 stop9h 22m
San Francisco
Tue 9/22
2:00 pm-11:05 pm
1 stop7h 05m
$296
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Thu 9/17
1:46 pm-7:58 pm
1 stop8h 12m
San Francisco
Thu 9/24
10:00 pm-8:16 am
1 stop8h 16m
$318
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Fri 12/4
8:00 am-3:45 pm
1 stop9h 45m
San Francisco
Sun 12/6
6:50 am-8:30 pm
2 stops11h 40m
$422
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Sat 10/3
5:30 pm-11:57 pm
1 stop8h 27m
San Francisco
Sun 10/11
9:30 pm-8:14 am
1 stop8h 44m
$429
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Sun 8/16
4:00 pm-11:05 pm
1 stop9h 05m
San Francisco
Wed 8/26
6:50 am-6:10 pm
2 stops9h 20m
$434
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Wed 9/23
2:27 pm-9:16 am
2 stops20h 49m
San Francisco
Fri 9/25
12:45 am-11:06 am
1 stop8h 21m
$447
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Fri 12/4
4:10 pm-10:51 pm
1 stop8h 41m
San Francisco
Mon 12/7
6:00 am-3:15 pm
1 stop7h 15m
$457
Cheapest one-way
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Wed 12/2
4:10 pm-12:15 am
1 stop10h 05m
$131
Quickest one-way
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Fri 10/16
4:20 pm-9:35 pm
1 stop7h 15m
$166
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Panama City to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.
ECP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Francisco
What is the cheapest month to book a flight from Panama City, Florida to San Francisco?
Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to San Francisco (average of $306). Flying from Panama City, Florida to San Francisco in February is currently the most expensive (average of $991). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 9, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Panama City to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Fairfield
Burlingame
Redwood City
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
San Bruno
Watsonville
Hayward
San Ramon
San Carlos
Turlock
Vallejo
San Lorenzo
Davis
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Panama City and San Francisco flights
Browse other Panama City and San Francisco flight options. Last updated on July 9, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on July 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 9, 2026.
Top 4 airlines flying from Panama City to San Francisco
Discover the top 4 airlines that operate flights from Panama City to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$297 | Average$436 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$306 | Average$471 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$354 | Average$463 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$358 | Average$547 | FlexibilityNo cancel fee | On-time71% |