$198+ Cheap flights from Panama City, FL to San Francisco (ECP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SFO
Jun 9 — Jun 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to San FranciscoExplore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/93:23 pm
ECP
- SFO
1 stop9h 07m
American Airlines
Tue 6/165:23 am
SFO
- ECP
1 stop7h 08m
American Airlines
Deal found 5/6![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/223:12 pm
ECP
- SFO
1 stop9h 16m
American Airlines
Sat 8/295:30 am
SFO
- ECP
1 stop6h 52m
American Airlines
Deal found 5/6![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:36 pm
ECP
- SFO
1 stop7h 51m
American Airlines
Mon 10/266:36 am
SFO
- ECP
1 stop8h 50m
American Airlines
Deal found 5/6![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:36 pm
ECP
- SFO
1 stop8h 29m
Delta
Sat 7/2510:45 pm
SFO
- ECP
1 stop7h 32m
Delta
Deal found 5/10![Delta logo]()
$408
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:15 am
ECP
- SFO
1 stop7h 40m
Delta
Thu 9/242:00 pm
SFO
- ECP
1 stop6h 46m
Delta
Deal found 5/8![Delta logo]()
$409
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:10 pm
ECP
- SFO
1 stop8h 29m
Delta
Mon 10/262:00 pm
SFO
- ECP
1 stop6h 47m
Delta
Deal found 5/9![Delta logo]()
$421
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:50 am
ECP
- SFO
1 stop9h 00m
Delta
Fri 7/246:00 am
SFO
- ECP
1 stop8h 22m
Delta
Deal found 5/9![Delta logo]()
$426
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:41 am
ECP
- SFO
1 stop9h 21m
Delta
Thu 5/281:45 pm
SFO
- ECP
1 stop7h 43m
Delta
Deal found 5/5![Delta logo]()
$428
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:50 pm
ECP
- SFO
1 stop8h 00m
Southwest
Fri 6/1911:00 am
SFO
- ECP
2 stops9h 00m
Southwest
Deal found 5/8![Southwest logo]()
$431
Best flights from Panama City to San FranciscoDiscover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
Discover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:10 pm
ECP
- SFO
1 stop9h 52m
Delta
Thu 9/242:00 pm
SFO
- ECP
1 stop6h 46m
Delta
Deal found 5/5![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:55 pm
ECP
- SFO
2 stops9h 30m
Southwest
Sat 7/259:25 am
SFO
- ECP
1 stop8h 55m
Southwest
Deal found 5/10![Southwest logo]()
$431
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:06 am
ECP
- SFO
1 stop6h 52m
American Airlines
Fri 7/246:45 am
SFO
- ECP
1 stop9h 32m
American Airlines
Deal found 5/7![American Airlines logo]()
$451
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:10 pm
ECP
- SFO
1 stop8h 29m
Delta
Mon 10/262:00 pm
SFO
- ECP
1 stop6h 47m
Delta
Deal found 5/9![Delta logo]()
$421
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:55 pm
ECP
- SFO
2 stops8h 30m
Southwest
Fri 6/1911:00 am
SFO
- ECP
2 stops9h 00m
Southwest
Deal found 5/8![Southwest logo]()
$436
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:12 pm
ECP
- SFO
1 stop9h 16m
American Airlines
Sat 7/2512:54 pm
SFO
- ECP
1 stop7h 41m
American Airlines
Deal found 5/9![American Airlines logo]()
$451
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:50 am
ECP
- SFO
1 stop9h 00m
Delta
Fri 7/246:00 am
SFO
- ECP
1 stop8h 22m
Delta
Deal found 5/9![Delta logo]()
$426
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/93:55 pm
ECP
- SFO
2 stops8h 30m
Southwest
Tue 6/1610:25 am
SFO
- ECP
2 stops9h 40m
Southwest
Deal found 5/7![Southwest logo]()
$436
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:50 pm
ECP
- SFO
1 stop9h 58m
Delta
Fri 5/2911:59 pm
SFO
- ECP
1 stop6h 31m
Delta
Deal found 5/5![Delta logo]()
$428
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:20 am
ECP
- SFO
1 stop10h 10m
Southwest
Fri 9/411:05 pm
SFO
- ECP
1 stop7h 55m
Southwest
Deal found 5/7![Southwest logo]()
$462
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/181:31 pm
ECP
- SFO
1 stop8h 46m
Delta
Mon 6/229:56 pm
SFO
- ECP
1 stop8h 18m
Delta
Deal found 5/8![Delta logo]()
$457
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:05 pm
ECP
- SFO
2 stops9h 00m
Southwest
Sun 8/2311:05 pm
SFO
- ECP
1 stop8h 20m
Southwest
Deal found 5/7![Southwest logo]()
$463
Last-minute flights from Panama City to San FranciscoDiscover last-minute flight deals from Panama City to San Francisco. Data last updated May 10, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Francisco. Data last updated May 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:50 pm
ECP
- SFO
1 stop7h 15m
Delta
Wed 5/2711:20 am
SFO
- ECP
1 stop9h 41m
Delta
Deal found 5/5![Delta logo]()
$486
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:00 am
ECP
- SFO
1 stop10h 02m
American Airlines
Fri 5/295:00 am
SFO
- ECP
1 stop8h 46m
American Airlines
Deal found 5/5![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:00 am
ECP
- SFO
2 stops12h 40m
American Airlines
Wed 5/2711:29 pm
SFO
- ECP
1 stop8h 06m
American Airlines
Deal found 5/5![American Airlines logo]()
$542
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:55 pm
ECP
- SFO
2 stops18h 09m
United Airlines
Thu 5/2812:45 am
SFO
- ECP
1 stop8h 17m
United Airlines
Deal found 5/6![United Airlines logo]()
$774
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:55 am
ECP
- SFO
2 stops10h 45m
Southwest
Sun 5/246:15 am
SFO
- ECP
1 stop8h 10m
Southwest
Deal found 5/5![Southwest logo]()
$522
One-way flights from Panama City to San FranciscoSearch for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
Search for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:22 pm
ECP
- SFO
1 stop7h 38m
American Airlines
Deal found 5/6![American Airlines logo]()
$198
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/83:23 pm
ECP
- SFO
1 stop9h 58m
American Airlines
Deal found 5/7![American Airlines logo]()
$200
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:00 am
ECP
- SFO
2 stops8h 40m
Southwest
Deal found 5/8![Southwest logo]()
$203
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:08 pm
ECP
- SFO
1 stop9h 37m
Delta
Deal found 5/10![Delta logo]()
$211
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:41 pm
ECP
- SFO
1 stop7h 55m
Delta
Deal found 5/8![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:55 pm
ECP
- SFO
2 stops8h 35m
Southwest
Deal found 5/7![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:35 am
ECP
- SFO
2 stops10h 10m
Southwest
Deal found 5/8![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:40 am
ECP
- SFO
2 stops8h 05m
Southwest
Deal found 5/7![Southwest logo]()
$275
This deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/19:00 am
ECP
- SFO
1 stop8h 03m
United Airlines
Deal found 5/9![United Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:51 pm
ECP
- SFO
1 stop9h 57m
American Airlines
Deal found 5/6![American Airlines logo]()
$289
Find flight deals from Panama City to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $395 (American Airlines) |
One-way from | $198 (American Airlines) |
Popular in | April |
Cheapest in | January |
Average price | $476 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Panama City to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Thu 9/17
4:10 pm-12:02 am
1 stop9h 52m
San Francisco
Thu 9/24
2:00 pm-10:46 pm
1 stop6h 46m
$399
Quickest round-trip
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Sat 9/19
4:10 pm-10:39 pm
1 stop8h 29m
San Francisco
Mon 10/26
2:00 pm-10:47 pm
1 stop6h 47m
$421
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Wed 7/15
7:50 am-2:50 pm
1 stop9h 00m
San Francisco
Fri 7/24
6:00 am-4:22 pm
1 stop8h 22m
$426
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Thu 5/28
2:50 pm-10:48 pm
1 stop9h 58m
San Francisco
Fri 5/29
11:59 pm-8:30 am
1 stop6h 31m
$428
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Wed 7/15
3:55 pm-11:25 pm
2 stops9h 30m
San Francisco
Sat 7/25
9:25 am-8:20 pm
1 stop8h 55m
$431
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Tue 6/16
3:55 pm-10:25 pm
2 stops8h 30m
San Francisco
Fri 6/19
11:00 am-10:00 pm
2 stops9h 00m
$436
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Tue 6/9
3:55 pm-10:25 pm
2 stops8h 30m
San Francisco
Tue 6/16
10:25 am-10:05 pm
2 stops9h 40m
$436
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Wed 7/15
10:06 am-2:58 pm
1 stop6h 52m
San Francisco
Fri 7/24
6:45 am-6:17 pm
1 stop9h 32m
$451
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Wed 7/15
3:12 pm-10:28 pm
1 stop9h 16m
San Francisco
Sat 7/25
12:54 pm-10:35 pm
1 stop7h 41m
$451
Panama CitySan Francisco
ECP - SFO
ECPSFO
Panama City NW Florida Beaches
Thu 6/18
1:31 pm-8:17 pm
1 stop8h 46m
San Francisco
Mon 6/22
9:56 pm-8:14 am
1 stop8h 18m
$457
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Panama City to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.
ECP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Francisco
What is the cheapest month to book a flight from Panama City, Florida to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to San Francisco (average of $402). Flying from Panama City, Florida to San Francisco in April is currently the most expensive (average of $607). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 10, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Panama City to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
Vallejo
San Lorenzo
Davis
Emeryville
Manteca
Elk Grove
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Alternative routes for Panama City to San Francisco
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Panama City and San Francisco flights
Browse other Panama City and San Francisco flight options. Last updated on May 10, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on May 10, 2026.
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Other flights to San Francisco
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Top 4 airlines flying from Panama City to San Francisco
Discover the top 4 airlines that operate flights from Panama City to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$297 | Average$425 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$306 | Average$471 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$358 | Average$476 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$445 | Average$498 | FlexibilityNo cancel fee | On-time63% |