HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$128+ Cheap flights from North Carolina to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — ECP
Jan 16 — Jan 231
Fri 1/16
Fri 1/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from North Carolina to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from North Carolina to Panama City

Cheapest flights from North Carolina to Panama City
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:18 pmMYR - ECP
1 stop5h 57mDelta
Wed 12/316:00 amECP - MYR
1 stop3h 24mDelta
Deal found 12/15$229
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:51 pmRDU - ECP
1 stop6h 24mDelta
Tue 1/67:20 amECP - RDU
1 stop3h 32mDelta
Deal found 12/15$321
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:30 pmORF - ECP
1 stop6h 45mDelta
Tue 12/307:02 pmECP - ORF
1 stop4h 16mDelta
Deal found 12/16$351
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:06 pmRDU - ECP
1 stop5h 09mDelta
Tue 12/307:02 pmECP - RDU
1 stop3h 55mDelta
Deal found 12/16$351
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:30 amGSO - ECP
1 stop7h 57mUnited Airlines
Thu 12/252:10 pmECP - GSO
1 stop5h 44mUnited Airlines
Deal found 12/16$354
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:01 amGSO - ECP
1 stop3h 55mAmerican Airlines
Sat 12/274:09 pmECP - GSO
1 stop4h 34mAmerican Airlines
Deal found 12/16$376
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:05 amORF - ECP
1 stop6h 14mDelta
Thu 1/18:02 amECP - ORF
1 stop5h 37mDelta
Deal found 12/16$377
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:58 pmTYS - ECP
1 stop5h 17mDelta
Sat 12/278:02 amECP - TYS
1 stop4h 40mDelta
Deal found 12/16$409
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:15 amORF - ECP
1 stop4h 04mDelta
Mon 12/296:00 amECP - ORF
1 stop5h 11mDelta
Deal found 12/16$416
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:58 amRDU - ECP
1 stop4h 21mDelta
Sun 1/46:00 amECP - RDU
1 stop6h 00mDelta
Deal found 12/15$417
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:30 pmILM - ECP
1 stop6h 47mDelta
Sun 1/46:00 amECP - ILM
1 stop3h 22mDelta
Deal found 12/16$419
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:10 amRDU - ECP
1 stop4h 10mSouthwest
Tue 12/306:35 pmECP - RDU
1 stop3h 40mSouthwest
Deal found 12/16$421

Find flight deals from North Carolina to Panama City

Keep the following information in mind while searching for North Carolina to Panama City flight deals. Data was last updated December 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$128
(Delta)

Popular in

December

Cheapest in

August

Average price

$526

Good round-trip deal

$403 or less
Provider with most accurate pricing for Raleigh-Durham-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City NW Florida Beaches flights.
Search Deals
From North Carolina to Panama City NW Florida Beaches
Search Deals
One-way flight from North Carolina to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($109 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from North Carolina to Panama City NW Florida Beaches.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Fly from

North Carolina

Fly to

Panama City

Route

Depart

Return

Price

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Fri 1/30

5:25 am-8:39 am

1 stop4h 14m

Panama City NW Florida Beaches

Sun 2/1

6:09 pm-11:54 pm

1 stop4h 45m

$249

RaleighPanama City

RDU - ECP

RDUECP

Raleigh-Durham

Sat 1/17

6:15 pm-10:51 pm

1 stop5h 36m

Panama City NW Florida Beaches

Tue 1/20

6:00 am-11:07 am

1 stop4h 07m

$255

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 1/31

6:23 am-11:33 am

1 stop6h 10m

Panama City NW Florida Beaches

Wed 2/4

12:03 pm-4:59 pm

1 stop3h 56m

$258

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 1/22

12:05 pm-5:33 pm

1 stop6h 28m

Panama City NW Florida Beaches

Mon 1/26

6:03 pm-11:15 pm

1 stop4h 12m

$263

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 1/23

6:23 am-11:33 am

1 stop6h 10m

Panama City NW Florida Beaches

Mon 1/26

6:03 pm-11:15 pm

1 stop4h 12m

$263

GreensboroPanama City

GSO - ECP

GSOECP

Greensboro/H. Point

Sat 2/28

7:56 pm-11:52 pm

1 stop4h 56m

Panama City NW Florida Beaches

Wed 3/4

8:20 am-3:32 pm

1 stop6h 12m

$269

WilmingtonPanama City

ILM - ECP

ILMECP

Wilmington New Hanover County

Fri 2/20

8:09 pm-11:52 pm

1 stop4h 43m

Panama City NW Florida Beaches

Sat 2/28

7:19 am-12:10 pm

1 stop3h 51m

$269

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Thu 1/15

5:40 am-9:12 am

1 stop4h 32m

Panama City NW Florida Beaches

Sun 1/18

6:00 am-10:15 am

1 stop3h 15m

$271

AshevillePanama City

AVL - ECP

AVLECP

Asheville Regional

Wed 1/7

6:15 pm-10:51 pm

1 stop5h 36m

Panama City NW Florida Beaches

Sat 1/10

7:20 am-11:59 am

1 stop3h 39m

$287

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 2/27

6:25 pm-11:52 pm

1 stop6h 27m

Panama City NW Florida Beaches

Wed 3/4

1:50 pm-8:46 pm

1 stop5h 56m

$290

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from North Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama City

What is the cheapest month to book a flight from North Carolina to Panama City, Florida?

Currently, August is the cheapest month in which you can book a flight from North Carolina to Panama City, Florida (average of $65). Flying from North Carolina to Panama City, Florida in March is currently the most expensive (average of $194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to ECP?

Find hourly flight availability from North Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 17, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 22% on flights from North Carolina to Panama City, Florida by exploring options for tickets at noon.

What is the cheapest day to fly from North Carolina to Panama City, Florida?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Panama City. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to Panama City, Florida flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from North Carolina to Panama City, Florida?

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from North Carolina?

    For a flight from North Carolina to Panama City, you will be flying into NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • How long is the flight from North Carolina to Panama City, Florida?

    For as low as $304, Delta can have you in Panama City, Florida from North Carolina in 4h. The distance between North Carolina and Panama City, Florida is about 390 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to Panama City, Florida one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $99. Southwest flights start at $192 while deals on American Airlines start at $198 one-way.

  • What are the most popular routes from North Carolina to Panama City, Florida?

    When deciding which route to take from North Carolina to Panama City, Florida consider Charlotte Douglas - Panama City NW Florida Beaches, Raleigh-Durham - Panama City NW Florida Beaches or Greensboro/H. Point - Panama City NW Florida Beaches as they are the most popular.

  • Can I find deals for flights from North Carolina to Panama City that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama City.

  • Can I find deals for business class flights from North Carolina to Panama City?

    Yes. Cheapflights offers flight deals from North Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama City, Florida?

    Currently, August is the cheapest month in which you can book a flight from North Carolina to Panama City, Florida (average of $65). Flying from North Carolina to Panama City, Florida in March is currently the most expensive (average of $194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Miami flights
Newark to Fort Lauderdale flights
Newark to Miami flights
LaGuardia to Fort Lauderdale flights
LaGuardia to Miami flights
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Orlando flights
Newark to West Palm Beach flights
Newark to Orlando flights
LaGuardia to Orlando flights
John F Kennedy Intl to West Palm Beach flights
Baltimore to Fort Lauderdale flights
John F Kennedy Intl to Tampa flights
Reagan-National to Miami flights
Dulles Intl to Miami flights
Newark to Tampa flights
O'Hare Intl to Fort Lauderdale flights
Dallas/Fort Worth to Orlando flights
Boston to Fort Lauderdale flights
Boston to Miami flights
Dulles Intl to Fort Lauderdale flights
O'Hare Intl to Orlando flights
LaGuardia to Tampa flights
Dulles Intl to Orlando flights
Detroit to Orlando flights
Detroit to Fort Lauderdale flights
Baltimore to Orlando flights
Philadelphia to Fort Lauderdale flights
O'Hare Intl to Miami flights
Minneapolis to Orlando flights
Baltimore to Miami flights
Boston to Orlando flights
Boston to Tampa flights
Philadelphia to Miami flights
LaGuardia to West Palm Beach flights
Philadelphia to Orlando flights
Reagan-National to Fort Lauderdale flights
Los Angeles to Miami flights
Cleveland to Orlando flights
Dallas/Fort Worth to Miami flights
Detroit to Miami flights
Newark to Fort Myers flights
Los Angeles to Orlando flights
Reagan-National to Orlando flights
Dallas/Fort Worth to Fort Lauderdale flights
Los Angeles to Fort Lauderdale flights
Minneapolis to Miami flights
O'Hare Intl to Tampa flights
John F Kennedy Intl to Fort Myers flights
Cleveland to Fort Lauderdale flights

Top 3 airlines flying from North Carolina to Panama City

Discover the top 3 airlines that operate flights from North Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$158Average$389FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$225Average$391FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$336Average$409FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.