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Panama City

$105+ Cheap flights from North Carolina to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — ECP
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from North Carolina to Panama City

Keep the following information in mind while searching for North Carolina to Panama City flight deals. Data was last updated September 15, 2025.

Round-trip from

$165
(Delta)

One-way from

$105
(Delta)

Popular in

November

Cheapest in

August

Average price

$320

Good round-trip deal

$333 or less

Good one-way deal

$397 or less
From North Carolina to Panama City NW Florida Beaches
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One-way flight from North Carolina to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 12% potential increase in price ($53 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from North Carolina to Panama City NW Florida Beaches.
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Price to beat on a one-way flight from North Carolina to Panama City NW Florida Beaches.
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Find flight deals from North Carolina to Panama City

Cheapest flights from North Carolina to Panama City
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:45 amTYS - ECP
1 stop5h 02mDelta
Tue 12/91:32 pmECP - TYS
1 stop4h 27mDelta
Deal found 9/12$165
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1810:50 pmCLT - ECP
Nonstop1h 54mAmerican Airlines
Mon 10/205:30 amECP - CLT
Nonstop1h 46mAmerican Airlines
Deal found 9/13$200
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:24 pmCLT - ECP
Nonstop1h 44mAmerican Airlines
Sun 11/97:15 amECP - CLT
Nonstop1h 50mAmerican Airlines
Deal found 9/14$214
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:50 amCLT - ECP
1 stop3h 57mDelta
Mon 12/154:26 pmECP - CLT
1 stop3h 59mDelta
Deal found 9/13$219
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:17 pmORF - ECP
1 stop5h 53mDelta
Thu 10/236:17 pmECP - ORF
1 stop5h 11mDelta
Deal found 9/14$227
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:19 pmCLT - ECP
Nonstop1h 56mAmerican Airlines
Sun 11/97:15 amECP - CLT
Nonstop1h 50mAmerican Airlines
Deal found 9/14$229
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:45 amCLT - ECP
1 stop4h 34mDelta
Sun 11/94:26 pmECP - CLT
1 stop4h 00mDelta
Deal found 9/14$234
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:45 amTYS - ECP
1 stop3h 23mDelta
Sat 10/46:00 amECP - TYS
1 stop3h 25mDelta
Deal found 9/12$242
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:30 amMYR - ECP
1 stop4h 59mAmerican Airlines
Mon 11/105:55 pmECP - MYR
1 stop3h 41mAmerican Airlines
Deal found 9/13$247
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:45 amTYS - ECP
1 stop3h 23mDelta
Wed 10/16:00 amECP - TYS
1 stop2h 44mDelta
Deal found 9/12$247
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:25 pmGSO - ECP
1 stop5h 36mDelta
Sun 12/76:00 amECP - GSO
1 stop4h 24mDelta
Deal found 9/14$249
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/215:19 pmORF - ECP
1 stop6h 34mAmerican Airlines
Thu 10/235:30 amECP - ORF
2 stops8h 23mAmerican Airlines
Deal found 9/14$249

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Fly from

North Carolina

Fly to

Panama City

Route

Depart

Return

Price

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 12/6

8:45 am-12:47 pm

1 stop5h 02m

Panama City NW Florida Beaches

Tue 12/9

1:32 pm-6:59 pm

1 stop4h 27m

$165

NorfolkPanama City

ORF - ECP

ORFECP

Norfolk

Wed 2/18

5:30 am-8:20 am

1 stop3h 50m

Panama City NW Florida Beaches

Thu 2/26

7:45 am-2:00 pm

1 stop5h 15m

$205

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Wed 12/10

9:50 am-12:47 pm

1 stop3h 57m

Panama City NW Florida Beaches

Mon 12/15

4:26 pm-9:25 pm

1 stop3h 59m

$219

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Wed 10/1

5:45 am-8:08 am

1 stop3h 23m

Panama City NW Florida Beaches

Sat 10/4

6:00 am-10:25 am

1 stop3h 25m

$242

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 11/5

7:30 am-11:29 am

1 stop4h 59m

Panama City NW Florida Beaches

Mon 11/10

5:55 pm-10:36 pm

1 stop3h 41m

$247

GreensboroPanama City

GSO - ECP

GSOECP

Greensboro/H. Point

Wed 12/3

2:25 pm-7:01 pm

1 stop5h 36m

Panama City NW Florida Beaches

Sun 12/7

6:00 am-11:24 am

1 stop4h 24m

$249

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Sat 10/4

5:30 am-8:08 am

1 stop3h 38m

Panama City NW Florida Beaches

Wed 10/8

6:00 am-11:00 am

1 stop4h 00m

$249

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Sat 11/1

11:41 am-3:38 pm

1 stop4h 57m

Panama City NW Florida Beaches

Sun 11/9

4:26 pm-9:26 pm

1 stop4h 00m

$249

NorfolkPanama City

ORF - ECP

ORFECP

Norfolk

Wed 12/10

7:26 am-4:47 pm

2 stops10h 21m

Panama City NW Florida Beaches

Mon 12/15

12:08 pm-10:53 pm

2 stops9h 45m

$254

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Fri 11/14

5:11 pm-8:32 pm

1 stop4h 21m

Panama City NW Florida Beaches

Sun 11/16

6:00 am-10:55 am

1 stop3h 55m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 55 results
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Best time to book a flight from North Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama City

What is the cheapest month to book a flight from North Carolina to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from North Carolina to Panama City, Florida (average of $346). Flying from North Carolina to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to ECP?

Find hourly flight availability from North Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Panama City, Florida as you normally would.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from North Carolina?

    For a flight from North Carolina to Panama City, you will be flying into NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • How long is the flight from North Carolina to Panama City, Florida?

    For as low as $282, Delta can have you in Panama City, Florida from North Carolina in 4h 15m. The distance between North Carolina and Panama City, Florida is about 556 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to Panama City, Florida one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $110. Delta flights start at $138 while deals on American Airlines start at $210 one-way.

  • What are the most popular routes from North Carolina to Panama City, Florida?

    When deciding which route to take from North Carolina to Panama City, Florida consider Charlotte Douglas - Panama City NW Florida Beaches, Raleigh-Durham - Panama City NW Florida Beaches or Knoxville McGhee Tyson - Panama City NW Florida Beaches as they are the most popular.

  • Can I find deals for flights from North Carolina to Panama City that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama City.

  • Can I find deals for business class flights from North Carolina to Panama City?

    Yes. Cheapflights offers flight deals from North Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from North Carolina to Panama City, Florida (average of $346). Flying from North Carolina to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for North Carolina to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from North Carolina to Panama City

Discover the top 3 airlines that operate flights from North Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$220Average$393FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$225Average$407FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$292Average$397FlexibilityNo cancel feeOn-time63%

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