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Panama City

$150+ Cheap flights from North Carolina to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — ECP
Apr 15 — Apr 221
Wed 4/15
Wed 4/22
1 adult, Economy
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Cheap flight deals from North Carolina to Panama City

Cheapest flights from North Carolina to Panama City
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:30 pm
TYS
-
ECP
1 stop4h 06m
Delta
Mon 5/187:41 am
ECP
-
TYS
1 stop5h 52m
Delta
Deal found 3/12$245
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:30 pm
TYS
-
ECP
1 stop4h 39m
Delta
Wed 6/37:41 am
ECP
-
TYS
1 stop5h 52m
Delta
Deal found 3/11$256
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:30 pm
TYS
-
ECP
1 stop4h 39m
Delta
Mon 6/87:05 pm
ECP
-
TYS
1 stop3h 41m
Delta
Deal found 3/11$257
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:15 am
TYS
-
ECP
2 stops11h 40m
Southwest
Sat 6/137:00 am
ECP
-
TYS
2 stops11h 35m
Southwest
Deal found 3/11$276
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:55 pm
TYS
-
ECP
1 stop6h 50m
Southwest
Tue 4/217:15 am
ECP
-
TYS
1 stop3h 45m
Southwest
Deal found 3/14$277
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:00 am
RDU
-
ECP
1 stop6h 21m
United Airlines
Wed 7/2210:25 am
ECP
-
RDU
1 stop6h 02m
United Airlines
Deal found 3/12$287
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:30 pm
TYS
-
ECP
1 stop4h 39m
Delta
Tue 6/96:00 am
ECP
-
TYS
1 stop4h 06m
Delta
Deal found 3/11$288
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:40 am
TYS
-
ECP
2 stops7h 20m
Southwest
Sat 5/97:20 am
ECP
-
TYS
1 stop3h 20m
Southwest
Deal found 3/15$292
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:52 pm
RDU
-
ECP
1 stop4h 23m
American Airlines
Mon 8/177:06 pm
ECP
-
RDU
1 stop3h 50m
American Airlines
Deal found 3/16$297
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:18 am
RDU
-
ECP
1 stop4h 17m
Delta
Tue 4/145:10 pm
ECP
-
RDU
1 stop4h 12m
Delta
Deal found 3/12$303
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:20 am
RDU
-
ECP
1 stop3h 57m
Delta
Tue 7/145:30 pm
ECP
-
RDU
1 stop3h 20m
Delta
Deal found 3/11$307
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 pm
GSO
-
ECP
1 stop6h 12m
Delta
Wed 5/65:49 am
ECP
-
GSO
1 stop4h 38m
Delta
Deal found 3/12$309

Find flight deals from North Carolina to Panama City

Keep the following information in mind while searching for North Carolina to Panama City flight deals. Data was last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$245
(Delta)

One-way from

$150
(Southwest)

Popular in

November

Cheapest in

August

Average price

$412

Good round-trip deal

$359 or less

Good one-way deal

$373 or less
Provider with most accurate pricing for Raleigh-Durham-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City NW Florida Beaches flights.
Search Deals
From North Carolina to Panama City NW Florida Beaches
Search Deals
One-way flight from North Carolina to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from North Carolina to Panama City NW Florida Beaches.
Search Deals
Price to beat on a one-way flight from North Carolina to Panama City NW Florida Beaches.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Wed 5/6

8:15 am-6:55 pm

2 stops11h 40m

Panama City NW Florida Beaches

Sat 6/13

7:00 am-7:35 pm

2 stops11h 35m

$276

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 5/23

7:45 am-5:50 pm

1 stop11h 05m

Panama City NW Florida Beaches

Wed 5/27

7:15 am-12:00 pm

1 stop3h 45m

$281

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 5/2

6:40 am-4:50 pm

2 stops11h 10m

Panama City NW Florida Beaches

Sat 5/9

7:20 am-11:40 am

1 stop3h 20m

$298

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 6/6

1:35 pm-9:55 pm

2 stops9h 20m

Panama City NW Florida Beaches

Sat 6/13

7:00 am-7:35 pm

2 stops11h 35m

$309

RaleighPanama City

RDU - ECP

RDUECP

Raleigh-Durham

Sat 4/11

11:00 am-7:00 pm

2 stops9h 00m

Panama City NW Florida Beaches

Sat 4/18

11:05 am-5:30 pm

1 stop5h 25m

$332

RaleighPanama City

RDU - ECP

RDUECP

Raleigh-Durham

Sun 5/24

7:30 am-12:34 pm

1 stop6h 04m

Panama City NW Florida Beaches

Wed 5/27

6:00 am-10:27 am

1 stop3h 27m

$335

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 3/28

6:35 am-9:05 am

1 stop3h 30m

Panama City NW Florida Beaches

Wed 4/1

1:20 pm-8:05 pm

1 stop5h 45m

$335

JacksonvillePanama City

OAJ - ECP

OAJECP

Jacksonville Albert J Ellis

Mon 7/27

5:40 am-8:17 am

1 stop3h 37m

Panama City NW Florida Beaches

Thu 7/30

9:23 am-1:40 pm

1 stop3h 17m

$347

JacksonvillePanama City

OAJ - ECP

OAJECP

Jacksonville Albert J Ellis

Wed 7/29

11:06 am-3:16 pm

1 stop5h 10m

Panama City NW Florida Beaches

Tue 8/4

6:00 am-11:14 am

1 stop4h 14m

$347

JacksonvillePanama City

OAJ - ECP

OAJECP

Jacksonville Albert J Ellis

Wed 7/29

11:06 am-3:16 pm

1 stop5h 10m

Panama City NW Florida Beaches

Mon 8/3

2:47 pm-10:17 pm

1 stop6h 30m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/15

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from North Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama City

What is the cheapest month to book a flight from North Carolina to Panama City, Florida?

Currently, May is the cheapest month in which you can book a flight from North Carolina to Panama City, Florida (average of $65). Flying from North Carolina to Panama City, Florida in March is currently the most expensive (average of $182). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to ECP?

Find hourly flight availability from North Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 16, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from North Carolina to Panama City, Florida by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from North Carolina?

    For a flight from North Carolina to Panama City, you will be flying into NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • How long is the flight from North Carolina to Panama City, Florida?

    For as low as $335, Southwest can have you in Panama City, Florida from North Carolina in 6h 04m. The distance between North Carolina and Panama City, Florida is about 556 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to Panama City, Florida one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $99. American Airlines flights start at $116 while deals on Southwest start at $203 one-way.

  • What are the most popular routes from North Carolina to Panama City, Florida?

    When deciding which route to take from North Carolina to Panama City, Florida consider Charlotte Douglas - Panama City NW Florida Beaches, Raleigh-Durham - Panama City NW Florida Beaches or Knoxville McGhee Tyson - Panama City NW Florida Beaches as they are the most popular.

  • Can I find deals for flights from North Carolina to Panama City that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama City.

  • Can I find deals for business class flights from North Carolina to Panama City?

    Yes. Cheapflights offers flight deals from North Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama City, Florida?

    Currently, May is the cheapest month in which you can book a flight from North Carolina to Panama City, Florida (average of $65). Flying from North Carolina to Panama City, Florida in March is currently the most expensive (average of $182). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for North Carolina to Panama City

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Top 3 airlines flying from North Carolina to Panama City

Discover the top 3 airlines that operate flights from North Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$158Average$414FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$397FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$346Average$436FlexibilityNo cancel feeOn-time63%

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