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Panama City

$492+ Cheap flights from Madrid, Spain (MAD) to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Madrid to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$642
(American Airlines)

One-way from

$492
(American Airlines)
Provider with most accurate pricing for Madrid Barajas-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Madrid Barajas-Panama City NW Florida Beaches flights.
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From Madrid Barajas to Panama City NW Florida Beaches
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One-way flight from Madrid Barajas to Panama City NW Florida Beaches
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Find flight deals from Madrid to Panama City

Cheapest flights from Madrid to Panama City
Explore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:00 am
MAD
-
ECP
2 stops37h 02m
United Airlines
Tue 2/31:10 pm
ECP
-
MAD
2 stops37h 05m
United Airlines
Deal found 1/15$568
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2312:40 pm
MAD
-
ECP
1 stop29h 53m
American Airlines
Tue 1/2712:03 pm
ECP
-
MAD
2 stops13h 47m
American Airlines
Deal found 1/14$600
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/23:55 pm
MAD
-
ECP
1 stop24h 36m
American Airlines
Wed 9/21:14 pm
ECP
-
MAD
1 stop13h 21m
American Airlines
Deal found 1/13$649
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:35 pm
MAD
-
ECP
2 stops31h 42m
United Airlines
Sun 11/16:40 am
ECP
-
MAD
2 stops23h 20m
United Airlines
Deal found 1/13$900
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:05 pm
MAD
-
ECP
2 stops22h 58m
American Airlines
Sun 11/15:04 pm
ECP
-
MAD
1 stop29h 41m
American Airlines
Deal found 1/14$955

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Madrid to Panama City that are best for you.

Fly from

Madrid

Fly to

Panama City

Route

Depart

Return

Price

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 1/30

6:00 am-12:02 pm

2 stops37h 02m

Panama City NW Florida Beaches

Tue 2/3

1:10 pm-9:15 am

2 stops37h 05m

$568

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 1/30

4:25 pm-11:33 am

2 stops26h 08m

Panama City NW Florida Beaches

Tue 2/3

7:02 am-6:15 am

1 stop16h 13m

$600

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

3:55 pm-9:31 am

1 stop24h 36m

Panama City NW Florida Beaches

Wed 9/2

1:14 pm-9:35 am

1 stop13h 21m

$649

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 4/8

10:25 am-11:46 pm

1 stop20h 21m

$492

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 4/8

7:30 am-9:58 pm

3 stops45h 28m

$2,379

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Compare providers for flights from Madrid to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madrid to Panama City in January.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Madrid-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Madrid-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Madrid-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Madrid-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Madrid to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Panama City

What is the cheapest month to book a flight from Madrid to Panama City, Florida?

Currently, November is the cheapest month in which you can book a flight from Madrid to Panama City, Florida (average of $545). Flying from Madrid to Panama City, Florida in July is currently the most expensive (average of $1,160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madrid to Panama City, Florida?

    A quick flight from Madrid to Panama City, Florida can take about 26h 08m. United Airlines provides one of the quickest options available for as low as $600. The distance between Madrid and Panama City, Florida is about 4513 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Madrid to Panama City that include hotel bookings?

    Yes. In addition to deals on Madrid to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Panama City.

  • Can I find deals for business class flights from Madrid to Panama City?

    Yes. Cheapflights offers flight deals from Madrid to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Panama City, Florida?

    Currently, November is the cheapest month in which you can book a flight from Madrid to Panama City, Florida (average of $545). Flying from Madrid to Panama City, Florida in July is currently the most expensive (average of $1,160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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