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Panama City

$128+ Cheap flights from Louisville to Panama City, FL (SDF - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — ECP
Feb 2 — Feb 91
Mon 2/2
Mon 2/9
1 adult, Economy
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Cheap flight deals from Louisville to Panama City

Cheapest flights from Louisville to Panama City
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 3, 2026.

This United Airlines deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:00 amSDF - ECP
1 stop7h 04mUnited Airlines
Wed 2/256:30 amECP - SDF
1 stop6h 01mUnited Airlines
Deal found 1/2$279
This American Airlines deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:50 pmSDF - ECP
1 stop4h 27mAmerican Airlines
Wed 2/252:00 pmECP - SDF
2 stops8h 16mAmerican Airlines
Deal found 1/2$285
This American Airlines deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/47:40 amSDF - ECP
1 stop8h 14mAmerican Airlines
Tue 2/1012:03 pmECP - SDF
1 stop5h 27mAmerican Airlines
Deal found 1/2$303
This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/148:00 pmSDF - ECP
1 stop4h 49mAmerican Airlines
Fri 2/204:34 pmECP - SDF
1 stop6h 53mAmerican Airlines
Deal found 12/31$311
This Delta deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/273:32 pmSDF - ECP
1 stop3h 42mDelta
Sat 1/317:20 amECP - SDF
1 stop3h 17mDelta
Deal found 1/2$314
This American Airlines deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/272:13 pmSDF - ECP
1 stop8h 06mAmerican Airlines
Sat 1/3112:03 pmECP - SDF
2 stops8h 13mAmerican Airlines
Deal found 1/2$319
This Southwest deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/275:35 amSDF - ECP
2 stops10h 20mSouthwest
Sat 1/3110:30 amECP - SDF
2 stops10h 55mSouthwest
Deal found 1/2$325
This American Airlines deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:00 amSDF - ECP
1 stop8h 04mAmerican Airlines
Mon 2/212:03 pmECP - SDF
2 stops9h 02mAmerican Airlines
Deal found 1/1$331
This United Airlines deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 amSDF - ECP
1 stop7h 04mUnited Airlines
Thu 3/122:10 pmECP - SDF
1 stop7h 03mUnited Airlines
Deal found 1/1$335

Find flight deals from Louisville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 3, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(United Airlines)

One-way from

$128
(Delta)

Popular in

December

Cheapest in

August

Average price

$372
Provider with most accurate pricing for Louisville Intl-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Panama City NW Florida Beaches flights.
Search Deals
From Louisville Intl to Panama City NW Florida Beaches
Search Deals
One-way flight from Louisville Intl to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 3, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Louisville

Fly to

Panama City

Route

Depart

Return

Price

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Wed 2/4

8:07 am-5:33 pm

2 stops10h 26m

Panama City NW Florida Beaches

Tue 2/10

1:34 pm-10:05 pm

1 stop7h 31m

$308

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 2/14

5:06 pm-11:49 pm

2 stops7h 43m

Panama City NW Florida Beaches

Fri 2/20

1:19 pm-9:26 pm

1 stop7h 07m

$316

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Thu 1/29

6:00 am-1:04 pm

1 stop8h 04m

Panama City NW Florida Beaches

Mon 2/2

12:03 pm-10:05 pm

2 stops9h 02m

$331

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Wed 3/4

6:45 am-2:55 pm

2 stops9h 10m

Panama City NW Florida Beaches

Thu 3/12

1:55 pm-9:55 pm

1 stop7h 00m

$340

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Thu 1/15

6:00 am-9:12 am

1 stop4h 12m

Panama City NW Florida Beaches

Tue 1/20

9:24 am-2:36 pm

1 stop4h 12m

$351

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sun 1/18

6:00 am-12:02 pm

1 stop7h 02m

Panama City NW Florida Beaches

Thu 1/22

1:10 pm-7:54 pm

1 stop5h 44m

$351

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 1/17

3:37 pm-7:48 pm

1 stop5h 11m

Panama City NW Florida Beaches

Mon 1/19

3:45 pm-8:56 pm

1 stop4h 11m

$351

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 1/17

3:37 pm-7:48 pm

1 stop5h 11m

Panama City NW Florida Beaches

Wed 1/21

7:20 am-11:37 am

1 stop3h 17m

$351

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 1/20

5:35 am-8:39 am

1 stop4h 04m

$128

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Mon 1/26

5:35 am-11:08 am

1 stop6h 33m

$163

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/1

Showing 1-10 of 20 results
1
2

Compare providers for flights from Louisville to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama City

How far ahead should I book a flight from Louisville to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Louisville to Panama City. Price data was last updated on January 2, 2026.

To ensure you get the cheapest price possible for a flight from Louisville to Panama City, Florida, you should look to book at least 81 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Louisville to Panama City, Florida?

Currently, August is the cheapest month in which you can book a flight from Louisville to Panama City, Florida (average of $71). Flying from Louisville to Panama City, Florida in April is currently the most expensive (average of $106). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 3, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Louisville to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,253 reviews

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,253 reviews
Southwest
8.0
Very good
4,253 reviews

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,023 reviews
Southwest
8.0
Very good
4,253 reviews

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,077 reviews
Southwest
8.0
Very good
4,253 reviews

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Panama City, Florida?

    There are many flights that can get you from Louisville to Panama City, Florida in 9h 10m. Fly via American Airlines or Southwest to get the fastest option. Louisville and Panama City, Florida are separated by a distance of 540 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Louisville to Panama City, Florida round-trip?

    According to our current data, Delta ($236), American Airlines ($256), and Southwest ($338) offers the cheapest pricing from Louisville to Panama City, Florida. Delta is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Louisville to Panama City that include hotel bookings?

    Yes. In addition to deals on Louisville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama City.

  • Can I find deals for business class flights from Louisville to Panama City?

    Yes. Cheapflights offers flight deals from Louisville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Panama City, Florida?

    Currently, August is the cheapest month in which you can book a flight from Louisville to Panama City, Florida (average of $71). Flying from Louisville to Panama City, Florida in April is currently the most expensive (average of $106). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top 3 airlines flying from Louisville to Panama City

Discover the top 3 airlines that operate flights from Louisville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$347FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$362FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$338Average$412FlexibilityNo cancel feeOn-time63%

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