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Panama City

$184+ Cheap flights from Louisville to Panama City, FL (SDF - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — ECP
Dec 19 — Dec 261
Fri 12/19
Fri 12/26
1 adult, Economy
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Find cheap flights from Louisville to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Louisville Intl to Panama City NW Florida Beaches are usually found in August or October, booked 81 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from Louisville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 19, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$303
(Delta)

One-way from

$184
(Delta)

Popular in

April

Cheapest in

August

Average price

$346
Provider with most accurate pricing for Louisville Intl-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Louisville Intl-Panama City NW Florida Beaches flights.
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From Louisville Intl to Panama City NW Florida Beaches
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One-way flight from Louisville Intl to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 4% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Louisville to Panama City

Cheapest flights from Louisville to Panama City
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 19, 2025.

This Southwest deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:25 pmSDF - ECP
1 stop3h 20mSouthwest
Thu 12/257:15 amECP - SDF
2 stops8h 20mSouthwest
Deal found 11/18$330
This Delta deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/278:35 amSDF - ECP
1 stop5h 12mDelta
Mon 12/229:22 amECP - SDF
1 stop5h 37mDelta
Deal found 11/17$332
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amSDF - ECP
1 stop3h 37mDelta
Thu 12/2511:06 amECP - SDF
1 stop3h 52mDelta
Deal found 11/16$337
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:25 amSDF - ECP
1 stop5h 08mAmerican Airlines
Mon 12/227:15 amECP - SDF
2 stops9h 04mAmerican Airlines
Deal found 11/17$347
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:35 amSDF - ECP
1 stop5h 12mDelta
Tue 12/2311:06 amECP - SDF
1 stop3h 53mDelta
Deal found 11/16$367
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amSDF - ECP
1 stop3h 37mDelta
Fri 12/267:02 pmECP - SDF
1 stop3h 54mDelta
Deal found 11/16$372
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:30 amSDF - ECP
1 stop5h 49mDelta
Sun 12/287:02 pmECP - SDF
1 stop3h 54mDelta
Deal found 11/16$377
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:12 amSDF - ECP
1 stop6h 10mAmerican Airlines
Fri 12/197:15 amECP - SDF
2 stops9h 04mAmerican Airlines
Deal found 11/18$382
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/164:57 pmSDF - ECP
2 stops7h 13mAmerican Airlines
Tue 12/237:15 amECP - SDF
2 stops9h 04mAmerican Airlines
Deal found 11/18$392
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:57 pmSDF - ECP
2 stops7h 13mAmerican Airlines
Mon 12/227:15 amECP - SDF
2 stops9h 04mAmerican Airlines
Deal found 11/17$397
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:24 pmSDF - ECP
1 stop5h 29mAmerican Airlines
Wed 12/2412:40 pmECP - SDF
1 stop7h 54mAmerican Airlines
Deal found 11/16$402

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Louisville

Fly to

Panama City

Route

Depart

Return

Price

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 1/13

3:37 pm-7:50 pm

1 stop5h 13m

Panama City NW Florida Beaches

Wed 1/14

7:20 am-11:37 am

1 stop3h 17m

$303

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 1/17

7:30 am-12:45 pm

1 stop6h 15m

Panama City NW Florida Beaches

Mon 1/19

7:20 am-2:36 pm

1 stop6h 16m

$311

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Thu 12/18

12:25 pm-2:45 pm

1 stop3h 20m

Panama City NW Florida Beaches

Thu 12/25

7:15 am-5:10 pm

1 stop8h 55m

$330

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 1/17

11:08 am-5:30 pm

2 stops7h 22m

Panama City NW Florida Beaches

Mon 1/19

1:34 pm-10:05 pm

1 stop7h 31m

$330

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sun 1/11

3:37 pm-7:50 pm

1 stop5h 13m

Panama City NW Florida Beaches

Sat 1/17

7:20 am-2:42 pm

1 stop6h 22m

$332

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Mon 12/22

2:20 pm-6:17 pm

1 stop4h 57m

Panama City NW Florida Beaches

Thu 12/25

11:06 am-3:58 pm

1 stop3h 52m

$332

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Fri 12/19

6:00 am-9:14 am

1 stop4h 14m

Panama City NW Florida Beaches

Thu 12/25

2:20 pm-8:00 pm

1 stop4h 40m

$332

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 12/20

6:51 pm-10:44 pm

1 stop4h 53m

Panama City NW Florida Beaches

Thu 12/25

11:06 am-3:58 pm

1 stop3h 52m

$332

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sun 12/21

6:00 am-8:37 am

1 stop3h 37m

Panama City NW Florida Beaches

Thu 12/25

8:02 am-12:51 pm

1 stop3h 49m

$332

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Mon 12/22

2:20 pm-6:17 pm

1 stop4h 57m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 13 results
1
2

Compare providers for flights from Louisville to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Panama City in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama City

How far ahead should I book a flight from Louisville to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Louisville to Panama City. Price data was last updated on November 14, 2025.

To ensure you get the cheapest price possible for a flight from Louisville to Panama City, Florida, you should look to book at least 81 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Louisville to Panama City, Florida?

Currently, August is the cheapest month in which you can book a flight from Louisville to Panama City, Florida (average of $71). Flying from Louisville to Panama City, Florida in April is currently the most expensive (average of $104). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to ECP?

Find hourly flight availability from Louisville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 19, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 22% on flights from Louisville to Panama City, Florida by exploring options for tickets in the evening.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 19, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Louisville to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,249 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,249 reviews
Southwest
8.0
Very good
4,249 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,004 reviews
Southwest
8.0
Very good
4,249 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,046 reviews
Southwest
8.0
Very good
4,249 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Panama City, Florida?

    There are many flights that can get you from Louisville to Panama City, Florida in 3h 20m. Fly via Delta, Southwest, or American Airlines to get the fastest option. Louisville and Panama City, Florida are separated by a distance of 540 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Louisville to Panama City, Florida round-trip?

    According to our current data, Delta ($237), American Airlines ($256), and Southwest ($338) offers the cheapest pricing from Louisville to Panama City, Florida. Delta is currently priced 34% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Louisville to Panama City, Florida one-way?

    One-way options have recently been found by users for as low as $184 on Delta. Other airlines that offer cheap prices include Southwest from $209 and American Airlines from $384 one-way.

  • Can I find deals for flights from Louisville to Panama City that include hotel bookings?

    Yes. In addition to deals on Louisville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama City.

  • Can I find deals for business class flights from Louisville to Panama City?

    Yes. Cheapflights offers flight deals from Louisville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Panama City, Florida?

    Currently, August is the cheapest month in which you can book a flight from Louisville to Panama City, Florida (average of $71). Flying from Louisville to Panama City, Florida in April is currently the most expensive (average of $104). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Top 3 airlines flying from Louisville to Panama City

Discover the top 3 airlines that operate flights from Louisville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$237Average$347FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$364FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$338Average$412FlexibilityNo cancel feeOn-time63%

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