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Panama City

$249+ Cheap flights from Key West to Panama City, FL (EYW - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — ECP
Nov 1 — Nov 81
Sat 11/1
Sat 11/8
1 adult, Economy
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Cheap flight deals from Key West to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$339
(Delta)

One-way from

$269
(Delta)
Provider with most accurate pricing for Key West-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Key West-Panama City NW Florida Beaches flights.
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From Key West to Panama City NW Florida Beaches
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One-way flight from Key West to Panama City NW Florida Beaches
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Find flight deals from Key West to Panama City

Cheapest flights from Key West to Panama City
Explore the most affordable flight options available from Key West to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2025.

This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/161:57 pmEYW - ECP
1 stop4h 15mDelta
Mon 10/201:35 pmECP - EYW
1 stop5h 31mDelta
Deal found 9/30$339
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:17 pmEYW - ECP
1 stop5h 53mDelta
Tue 10/216:00 amECP - EYW
1 stop4h 27mDelta
Deal found 10/2$379
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:47 pmEYW - ECP
2 stops6h 57mAmerican Airlines
Tue 10/216:49 amECP - EYW
2 stops9h 27mAmerican Airlines
Deal found 10/2$509
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:47 pmEYW - ECP
2 stops6h 57mAmerican Airlines
Mon 10/205:30 amECP - EYW
1 stop5h 40mAmerican Airlines
Deal found 9/30$526

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
Use the filters below to find and compare flights from Key West to Panama City that are best for you.

Fly from

Key West

Fly to

Panama City

Route

Depart

Return

Price

Key WestPanama City

EYW - ECP

EYWECP

Key West

Thu 10/16

1:57 pm-5:12 pm

1 stop4h 15m

Panama City NW Florida Beaches

Mon 10/20

1:35 pm-8:06 pm

1 stop5h 31m

$339

Key WestPanama City

EYW - ECP

EYWECP

Key West

Fri 10/17

6:17 pm-11:10 pm

1 stop5h 53m

Panama City NW Florida Beaches

Tue 10/21

6:00 am-11:27 am

1 stop4h 27m

$379

Key WestPanama City

EYW - ECP

EYWECP

Key West

Thu 10/16

5:47 pm-11:44 pm

2 stops6h 57m

Panama City NW Florida Beaches

Mon 10/20

5:30 am-12:10 pm

1 stop5h 40m

$526

Key WestPanama City

EYW - ECP

EYWECP

Key West

Fri 10/17

1:25 pm-11:44 pm

2 stops11h 19m

Panama City NW Florida Beaches

Tue 10/21

6:49 am-2:46 pm

1 stop6h 57m

$534

Key WestPanama City

EYW - ECP

EYWECP

Key West

Tue 3/24

7:00 am-12:40 pm

1 stop6h 40m

$249

Key WestPanama City

EYW - ECP

EYWECP

Key West

Thu 3/19

8:10 am-1:38 pm

1 stop6h 28m

$249

Key WestPanama City

EYW - ECP

EYWECP

Key West

Mon 3/9

2:35 pm-7:38 pm

1 stop6h 03m

$269

Key WestPanama City

EYW - ECP

EYWECP

Key West

Tue 3/24

8:10 am-1:38 pm

1 stop6h 28m

$279

Key WestPanama City

EYW - ECP

EYWECP

Key West

Mon 3/9

8:01 pm-10:00 am

2 stops14h 59m

$359

Key WestPanama City

EYW - ECP

EYWECP

Key West

Thu 3/19

4:05 pm-7:52 pm

3 stops28h 47m

$554

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/2

Showing 1-10 of 12 results
1
2

Compare providers for flights from Key West to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Key West to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Panama City, Florida?

    Delta and American Airlines can get you from Key West to Panama City, Florida in just under 4h 15m. Your travel time can differ by up to 2h 42m. The distance between Key West and Panama City, Florida is about 471 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Key West to Panama City that include hotel bookings?

    Yes. In addition to deals on Key West to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Panama City.

  • Can I find deals for business class flights from Key West to Panama City?

    Yes. Cheapflights offers flight deals from Key West to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Key West to Panama City, Florida (average of $346). Flying from Key West to Panama City, Florida in March is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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