What is the cheapest airline to fly from Key West to Panama City, Florida round-trip?

Delta, at $297, was found to be the cheapest airline from Key West to Panama City, Florida..

What is the cheapest day to fly from Key West to Panama City, Florida?

Travelers seeking maximum savings on their Key West to Panama City, Florida flight should consider departing on Wednesday mornings when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

What is the cheapest day to fly round-trip from Key West to Panama City, Florida?

Flights from Key West to Panama City, Florida are found to be more expensive on Tuesday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Panama City, Florida.

What is the cheapest time of day to fly from EYW to ECP?

When flying from Key West to Panama City, Florida, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Key West to Panama City that include hotel bookings?

Yes. In addition to deals on Key West to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Key West to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Panama City.

Can I find deals for business class flights from Key West to Panama City?

Yes. Cheapflights offers flight deals from Key West to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$297+ Flights from Key West to Panama City, FL

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Cheap flight deals from Key West to Panama City

Round-trip from	$297 (Delta)

From Key West to Panama City NW Florida Beaches

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Cheapest flights from Key West to Panama City
Explore the most affordable flight options available from Key West to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Sat 9/136:10 pmEYW - ECP

1 stop5h 53mDelta

Tue 9/166:00 amECP - EYW

1 stop3h 55mDelta

Deal found 6/30

$297

Best flights from Key West to Panama City
Discover carefully curated flight deals from Key West to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2025.

Sat 9/136:10 pmEYW - ECP

1 stop5h 53mDelta

Tue 9/166:00 amECP - EYW

1 stop3h 55mDelta

Deal found 6/30

$297

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key West to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Key WestPanama City

EYW - ECP

EYWECP

Key West

Sat 9/13

6:10 pm-11:03 pm

1 stop5h 53m

Panama City NW Florida Beaches

Tue 9/16

6:00 am-10:55 am

1 stop3h 55m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Key West to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Key West with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to Panama City

What is the cheapest month to book a flight from Key West to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Key West to Panama City, Florida (average of $346). Flying from Key West to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Read reviews from past customers who have flown Delta from Key West to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

8.0

Very good

7,983 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

What is the cheapest airline to fly from Key West to Panama City, Florida round-trip?
Delta, at $297, was found to be the cheapest airline from Key West to Panama City, Florida..
Can I find deals for flights from Key West to Panama City that include hotel bookings?
Yes. In addition to deals on Key West to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Key West to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Panama City.
Can I find deals for business class flights from Key West to Panama City?
Yes. Cheapflights offers flight deals from Key West to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Key West to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from Key West to Panama City, Florida (average of $346). Flying from Key West to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$297+ Cheap flights from Key West to Panama City, FL (EYW - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Key West to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Key West to Panama City

Round-trip from

Find flight deals from Key West to Panama City

Cheapest flights from Key West to Panama CityExplore the most affordable flight options available from Key West to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Explore the most affordable flight options available from Key West to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key West to Panama City that are best for you.

Best time to book a flight from Key West to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Key West with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Key West to Panama City

What is the cheapest month to book a flight from Key West to Panama City, Florida?

Reviews of airlines servicing Panama City

Read reviews from past customers who have flown Delta from Key West to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Key West to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What is the cheapest airline to fly from Key West to Panama City, Florida round-trip?

Can I find deals for flights from Key West to Panama City that include hotel bookings?

How can I find direct flights from Key West to Panama City?

Can I find deals for business class flights from Key West to Panama City?

What is the cheapest month to book a flight from Key West to Panama City, Florida?

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Cheapest flights from Key West to Panama City
Explore the most affordable flight options available from Key West to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.