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North Carolina

$112+ Cheap flights from Knoxville (TYS) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — RDU
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Knoxville to North Carolina

Keep the following information in mind while searching for Knoxville to North Carolina flight deals. Data was last updated September 17, 2025.

Round-trip from

$176
(Kiwi.com)

One-way from

$112
(Kiwi.com)

Popular in

September

Cheapest in

November

Average price

$427

Good round-trip deal

$285 or less

Good one-way deal

$206 or less
From Knoxville McGhee Tyson to North Carolina
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One-way flight from Knoxville McGhee Tyson to North Carolina
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Highest demand for flights based on searches. 4% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to North Carolina.
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Price to beat on a one-way flight from Knoxville McGhee Tyson to North Carolina.
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Find flight deals from Knoxville to North Carolina

Cheapest flights from Knoxville to North Carolina
Explore the most affordable flight options available from Knoxville to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:42 pmTYS - CLT
1 stop13h 55mMultiple Airlines
Sun 11/165:06 pmCLT - TYS
1 stop25h 30mMultiple Airlines
Deal found 9/16$176
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1312:08 pmTYS - CLT
1 stop8h 51mMultiple Airlines
Mon 10/208:55 amCLT - TYS
1 stop14h 21mMultiple Airlines
Deal found 9/15$222
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:19 pmTYS - ORF
1 stop5h 04mDelta
Wed 10/226:04 amORF - TYS
1 stop5h 52mDelta
Deal found 9/15$225
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:44 amTYS - ILM
1 stop3h 47mDelta
Sun 10/196:00 amILM - TYS
1 stop3h 20mDelta
Deal found 9/17$229
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:03 amTYS - CLT
1 stop24h 23mAmerican Airlines
Sun 10/198:20 amCLT - TYS
Nonstop1h 12mAmerican Airlines
Deal found 9/16$229
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1811:08 amTYS - CLT
1 stop12h 20mMultiple Airlines
Sun 10/1910:06 pmCLT - TYS
1 stop11h 50mMultiple Airlines
Deal found 9/16$231
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:35 pmTYS - RDU
1 stop18h 48mMultiple Airlines
Mon 9/2912:21 pmRDU - TYS
1 stop5h 13mMultiple Airlines
Deal found 9/15$236
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:43 pmTYS - ILM
1 stop5h 25mAmerican Airlines
Sat 10/42:50 pmILM - TYS
1 stop4h 15mAmerican Airlines
Deal found 9/15$239
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:59 amTYS - RDU
1 stop8h 40mMultiple Airlines
Mon 11/39:09 amRDU - TYS
1 stop25h 24mMultiple Airlines
Deal found 9/15$239
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2512:08 pmTYS - ORF
2 stops23h 16mMultiple Airlines
Sun 9/285:38 pmORF - TYS
1 stop23h 56mMultiple Airlines
Deal found 9/15$242
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:26 pmTYS - CLT
1 stop18h 58mMultiple Airlines
Sun 11/210:06 pmCLT - TYS
1 stop14h 27mMultiple Airlines
Deal found 9/14$244
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/154:26 pmTYS - CLT
1 stop7h 02mMultiple Airlines
Wed 10/225:45 amCLT - TYS
1 stop9h 51mMultiple Airlines
Deal found 9/15$255

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Knoxville to North Carolina that are best for you.

Fly from

Knoxville

Fly to

North Carolina

Route

Depart

Return

Price

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 11/14

6:42 pm-8:37 am

1 stop13h 55m

Charlotte Douglas

Sun 11/16

9:20 pm-6:36 pm

2 stops21h 16m

$213

KnoxvilleNorfolk

TYS - ORF

TYSORF

Knoxville McGhee Tyson

Wed 10/15

5:19 pm-10:23 pm

1 stop5h 04m

Norfolk

Wed 10/22

6:04 am-11:56 am

1 stop5h 52m

$225

KnoxvilleNorfolk

TYS - ORF

TYSORF

Knoxville McGhee Tyson

Tue 10/21

5:19 pm-10:23 pm

1 stop5h 04m

Norfolk

Tue 10/28

4:23 pm-8:10 pm

1 stop3h 47m

$225

KnoxvilleWilmington

TYS - ILM

TYSILM

Knoxville McGhee Tyson

Wed 10/22

8:15 am-1:46 pm

1 stop5h 31m

Wilmington New Hanover County

Mon 10/27

5:00 am-9:32 am

1 stop4h 32m

$229

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Sat 10/18

6:03 am-6:26 am

1 stop24h 23m

Charlotte Douglas

Sun 10/19

8:20 am-9:32 am

Nonstop1h 12m

$229

KnoxvilleWilmington

TYS - ILM

TYSILM

Knoxville McGhee Tyson

Wed 10/15

5:44 am-9:31 am

1 stop3h 47m

Wilmington New Hanover County

Sun 10/19

6:00 am-9:20 am

1 stop3h 20m

$229

KnoxvilleWilmington

TYS - ILM

TYSILM

Knoxville McGhee Tyson

Fri 10/17

5:44 am-9:31 am

1 stop3h 47m

Wilmington New Hanover County

Tue 10/21

5:55 pm-11:07 pm

1 stop5h 12m

$229

KnoxvilleWilmington

TYS - ILM

TYSILM

Knoxville McGhee Tyson

Fri 10/17

5:44 am-9:31 am

1 stop3h 47m

Wilmington New Hanover County

Sun 10/19

6:00 am-9:20 am

1 stop3h 20m

$229

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Mon 10/13

7:02 pm-11:28 pm

2 stops28h 26m

Charlotte Douglas

Mon 10/20

8:55 am-11:16 pm

1 stop14h 21m

$230

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Sat 10/18

11:08 am-11:28 pm

1 stop12h 20m

Charlotte Douglas

Sun 10/19

10:06 pm-9:56 am

1 stop11h 50m

$231

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 60 results
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Best time to book a flight from Knoxville to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to North Carolina

What is the cheapest month to book a flight from Knoxville to North Carolina?

Currently, August is the cheapest month in which you can book a flight from Knoxville to North Carolina (average of $206). Flying from Knoxville to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to NC?

Find hourly flight availability from Knoxville to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Knoxville to North Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to North Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to North Carolina?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to North Carolina from Knoxville.

  • How long is the flight from Knoxville to North Carolina?

    Departing from Knoxville to North Carolina will take you 5h 04m. The distance between Knoxville and North Carolina is about 440 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Knoxville to North Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $149. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Knoxville to North Carolina for a low price.

  • What are the most popular routes from Knoxville to North Carolina?

    When deciding which route to take from Knoxville to North Carolina consider Knoxville McGhee Tyson - Norfolk, Knoxville McGhee Tyson - Myrtle Beach Intl or Knoxville McGhee Tyson - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from Knoxville to North Carolina that include hotel bookings?

    Yes. In addition to deals on Knoxville to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to North Carolina.

  • Can I find deals for business class flights from Knoxville to North Carolina?

    Yes. Cheapflights offers flight deals from Knoxville to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to North Carolina?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to North Carolina (average of $206). Flying from Knoxville to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to North Carolina

Discover the top 3 airlines that operate flights from Knoxville to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$176Average$320FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$218Average$278FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$218Average$377FlexibilityNo cancel feeOn-time71%

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