North Carolina

$104+ Cheap flights from Knoxville (TYS) to North Carolina

TYS — CLT
Dec 9 — Dec 161
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Cheap flight deals from Knoxville to North Carolina

Cheapest flights from Knoxville to North Carolina

Tue 12/229:26 am -
1 stop11h 53m
Tue 12/299:52 pm -
1 stop24h 44m
Deal found 11/6$231
Tue 12/14:32 pm -
1 stop20h 43m
Sat 12/54:22 pm -
2 stops40h 05m
Deal found 11/6$249
Sat 12/199:32 pm -
1 stop24h 59m
Tue 12/296:00 am -
1 stop16h 46m
Deal found 11/6$254
Fri 11/207:00 am -
1 stop7h 20m
Sun 11/229:46 pm -
1 stop25h 43m
Deal found 11/9$269
Thu 12/248:18 am -
1 stop3h 41m
Fri 12/2511:15 am -
1 stop5h 01m
Deal found 11/5$273
Tue 12/14:32 pm -
1 stop20h 43m
Sun 12/68:59 am -
1 stop23h 28m
Deal found 11/6$278
Fri 11/209:32 pm -
1 stop12h 34m
Tue 11/2412:42 pm -
1 stop28h 07m
Deal found 11/5$290
Wed 12/95:40 am -
1 stop6h 11m
Thu 12/108:35 am -
1 stop6h 38m
Deal found 11/5$305
Sat 12/1211:11 am -
1 stop33h 49m
Sun 12/1310:40 pm -
Nonstop1h 19m
Deal found 11/9$307
Thu 12/38:00 am -
1 stop13h 07m
Mon 12/73:10 pm -
1 stop21h 57m
Deal found 11/6$319
Fri 11/131:17 pm -
1 stop19h 54m
Mon 11/169:53 pm -
2 stops38h 13m
Deal found 11/6$319
Mon 12/75:40 am -
1 stop4h 26m
Mon 12/74:50 pm -
1 stop3h 24m
Deal found 11/9$325

Find flight deals from Knoxville to North Carolina

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$210
(Kiwi.com)

One-way from

$104
(Kiwi.com)

Popular in

March

Cheapest in

June

Average price

$701

Good round-trip deal

$411 or less

Good one-way deal

$228 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Charlotte Douglas flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Charlotte Douglas flights.
From Knoxville McGhee Tyson to North Carolina
One-way flight from Knoxville McGhee Tyson to North Carolina
Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in November 2026
Price to beat on a round-trip flight from Knoxville McGhee Tyson to North Carolina.
Price to beat on a one-way flight from Knoxville McGhee Tyson to North Carolina.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Knoxville to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleRaleigh

TYS Knoxville McGhee Tyson - RDU Raleigh-Durham

TYSRDU

Knoxville McGhee Tyson

Mon 12/21

6:00 am-2:27 pm

1 stop8h 27m

Raleigh-Durham

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$104

KnoxvilleRaleigh

TYS Knoxville McGhee Tyson - RDU Raleigh-Durham

TYSRDU

Knoxville McGhee Tyson

Wed 11/25

11:38 am-8:53 pm

1 stop9h 15m

Raleigh-Durham

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$135

KnoxvilleRaleigh

TYS Knoxville McGhee Tyson - RDU Raleigh-Durham

TYSRDU

Knoxville McGhee Tyson

Mon 11/23

7:00 am-2:20 pm

1 stop7h 20m

Raleigh-Durham

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$135

KnoxvilleCharlotte

TYS Knoxville McGhee Tyson - CLT Charlotte Douglas

TYSCLT

Knoxville McGhee Tyson

Sat 11/21

4:51 pm-9:35 am

1 stop16h 44m

Charlotte Douglas

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$178

KnoxvilleRaleigh

TYS Knoxville McGhee Tyson - RDU Raleigh-Durham

TYSRDU

Knoxville McGhee Tyson

Sun 11/29

11:38 am-9:59 am

2 stops46h 21m

Raleigh-Durham

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$190

KnoxvilleRaleigh

TYS Knoxville McGhee Tyson - RDU Raleigh-Durham

TYSRDU

Knoxville McGhee Tyson

Tue 12/29

12:02 pm-9:40 pm

1 stop9h 38m

Raleigh-Durham

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$190

KnoxvilleRaleigh

TYS Knoxville McGhee Tyson - RDU Raleigh-Durham

TYSRDU

Knoxville McGhee Tyson

Sun 11/22

11:04 am-10:40 pm

1 stop11h 36m

Raleigh-Durham

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$209

KnoxvilleRaleigh

TYS Knoxville McGhee Tyson - RDU Raleigh-Durham

TYSRDU

Knoxville McGhee Tyson

Mon 11/30

1:28 pm-11:57 pm

2 stops34h 29m

Raleigh-Durham

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$216

KnoxvilleRaleigh

TYS Knoxville McGhee Tyson - RDU Raleigh-Durham

TYSRDU

Knoxville McGhee Tyson

Tue 12/29

7:15 pm-9:30 am

2 stops14h 15m

Raleigh-Durham

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$236

KnoxvilleAsheville

TYS Knoxville McGhee Tyson - AVL Asheville Regional

TYSAVL

Knoxville McGhee Tyson

Sat 12/19

9:32 pm-10:31 pm

1 stop24h 59m

Asheville Regional

Tue 12/29

6:00 am-10:46 pm

1 stop16h 46m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Knoxville with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Knoxville to North Carolina

What is the cheapest month to book a flight from Knoxville to North Carolina?

Currently, December is the cheapest month in which you can book a flight from Knoxville to North Carolina (average of $382). Flying from Knoxville to North Carolina in July is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to NC?

A simple way to save on the total cost of your ticket is to fly from Knoxville to North Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 12% on your trip compared to booking a flight in the afternoon.

Weekly flight availability from Knoxville to North Carolina

The most flights from TYS to USNC are scheduled on a Thursday (12 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (8 on average).

What is the cheapest day to fly from Knoxville to North Carolina?

Travelers seeking maximum savings on their Knoxville to North Carolina flight should consider departing on Friday evenings when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing North Carolina

Read reviews from past customers who have flown Delta and American Airlines from Knoxville to North Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.8

Crew

8.5

Comfort

7.8

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Overall

7.8

Crew

8.5

Comfort

7.8

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Overall

7.8

Crew

8.5

Comfort

7.8

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

  • What airport do you fly from for flights from Knoxville to North Carolina?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to North Carolina from Knoxville.

  • How popular is this Knoxville to North Carolina flight route?

  • How long is the flight from Knoxville to North Carolina?

    Departing from Knoxville to North Carolina will take you 6h 11m. The distance between Knoxville and North Carolina is about 291 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Knoxville to North Carolina one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $111. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Knoxville to North Carolina for a low price.

  • What are the most popular routes from Knoxville to North Carolina?

  • What are the most reliable airlines from Knoxville to North Carolina?

    No one likes to see their flight delayed. When booking a flight from Knoxville to North Carolina consider choosing Piedmont Airlines (90%), American Airlines (85%) or PSA Airlines (81%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Knoxville to North Carolina?

    The cheapest flight price from Knoxville to North Carolina is $151. On average you can expect to pay $831. The most popular route, (Knoxville McGhee Tyson - Charlotte Douglas), can usually be booked for $232.

  • Can I find deals for flights from Knoxville to North Carolina that include hotel bookings?

    Yes. In addition to deals on Knoxville to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to North Carolina.

  • Can I find deals for business class flights from Knoxville to North Carolina?

    Yes. Cheapflights offers flight deals from Knoxville to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to North Carolina?

    Currently, December is the cheapest month in which you can book a flight from Knoxville to North Carolina (average of $382). Flying from Knoxville to North Carolina in July is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Knoxville to North Carolina

Top 2 airlines flying from Knoxville to North Carolina

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$465FlexibilityNo cancel feeOn-time71%
DeltaCheapest$288Average$605FlexibilityNo cancel feeOn-timeN/A

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