HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
North Carolina

$218+ Cheap flights from Columbia, MO (COU) to North Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
COU — RDU
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbia to North Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbia to North Carolina

Keep the following information in mind while searching for Columbia to North Carolina flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$218
(United Airlines)
Provider with most accurate pricing for Columbia Regional-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-Raleigh-Durham flights.
Search Deals
From Columbia Regional to North Carolina
Search Deals

Find flight deals from Columbia to North Carolina

Cheapest flights from Columbia to North Carolina
Explore the most affordable flight options available from Columbia to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/233:02 pmCOU - TYS
1 stop6h 53mUnited Airlines
Sat 12/135:54 pmTYS - COU
1 stop4h 28mUnited Airlines
Deal found 10/30$218
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/113:02 pmCOU - ORF
2 stops7h 25mUnited Airlines
Tue 12/24:45 pmORF - COU
1 stop5h 37mUnited Airlines
Deal found 10/30$289
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:37 pmCOU - TYS
1 stop16h 06mAmerican Airlines
Tue 11/187:59 amTYS - COU
1 stop8h 09mAmerican Airlines
Deal found 10/30$417
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:01 amCOU - CLT
1 stop5h 24mAmerican Airlines
Tue 11/254:39 pmCLT - COU
1 stop6h 16mAmerican Airlines
Deal found 10/28$418
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:05 pmCOU - CLT
1 stop5h 10mAmerican Airlines
Sat 1/2410:20 amCLT - COU
1 stop5h 28mAmerican Airlines
Deal found 10/29$419
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:00 amCOU - TYS
1 stop4h 17mUnited Airlines
Mon 11/178:26 amTYS - COU
1 stop7h 00mUnited Airlines
Deal found 10/29$428
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:32 amCOU - ORF
1 stop4h 39mAmerican Airlines
Tue 12/21:07 pmORF - COU
1 stop6h 29mAmerican Airlines
Deal found 10/30$437
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:09 amCOU - MYR
1 stop8h 32mAmerican Airlines
Wed 11/127:30 amMYR - COU
2 stops8h 38mAmerican Airlines
Deal found 10/29$476
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:11 amCOU - MYR
1 stop8h 28mAmerican Airlines
Sat 12/135:43 pmMYR - COU
1 stop5h 52mAmerican Airlines
Deal found 10/29$480
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:02 pmCOU - TYS
2 stops28h 18mUnited Airlines
Tue 11/185:45 amTYS - COU
2 stops9h 41mUnited Airlines
Deal found 10/30$488
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:00 amCOU - CLT
2 stops11h 20mUnited Airlines
Tue 11/255:35 pmCLT - COU
1 stop4h 44mUnited Airlines
Deal found 10/28$494
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:32 amCOU - AVL
1 stop11h 01mAmerican Airlines
Sun 11/1611:21 amAVL - COU
1 stop11h 34mAmerican Airlines
Deal found 10/30$507

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Columbia to North Carolina that are best for you.

Fly from

Columbia

Fly to

North Carolina

Route

Depart

Return

Price

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sun 11/23

3:02 pm-10:55 pm

1 stop6h 53m

Knoxville McGhee Tyson

Sat 12/13

5:54 pm-9:22 pm

1 stop4h 28m

$218

ColumbiaNorfolk

COU - ORF

COUORF

Columbia Regional

Tue 11/11

3:02 pm-11:27 pm

2 stops7h 25m

Norfolk

Tue 12/2

4:45 pm-9:22 pm

1 stop5h 37m

$289

ColumbiaNorfolk

COU - ORF

COUORF

Columbia Regional

Wed 4/22

8:00 am-2:16 pm

1 stop5h 16m

Norfolk

Sat 4/25

5:15 pm-9:10 pm

1 stop4h 55m

$308

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 4/4

8:00 am-1:18 pm

1 stop4h 18m

Knoxville McGhee Tyson

Wed 4/8

5:50 am-2:29 pm

2 stops9h 39m

$329

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Sat 4/4

12:04 pm-7:16 pm

1 stop6h 12m

Charlotte Douglas

Wed 4/8

9:20 am-2:38 pm

1 stop6h 18m

$400

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Wed 3/11

11:15 am-5:17 pm

1 stop5h 02m

Charlotte Douglas

Sat 3/14

6:20 am-10:18 am

1 stop4h 58m

$400

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Sat 4/4

8:00 am-9:33 pm

2 stops12h 33m

Charlotte Douglas

Wed 4/8

7:30 am-2:29 pm

2 stops7h 59m

$411

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Thu 11/13

8:00 am-1:17 pm

1 stop4h 17m

Knoxville McGhee Tyson

Mon 11/17

8:26 am-2:26 pm

1 stop7h 00m

$428

ColumbiaNorfolk

COU - ORF

COUORF

Columbia Regional

Tue 11/11

6:32 am-12:11 pm

1 stop4h 39m

Norfolk

Tue 12/2

1:07 pm-6:36 pm

1 stop6h 29m

$437

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Fri 11/14

7:37 pm-12:43 pm

1 stop16h 06m

Knoxville McGhee Tyson

Tue 11/18

12:46 pm-9:55 pm

2 stops10h 09m

$452

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from Columbia to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to North Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated October 30, 2025.
See what other customers who have flown with American Airlines from Columbia to North Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,034 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
11,034 reviews
American Airlines
7.2
Good
11,034 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Columbia to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to North Carolina?

    Columbia Regional (COU) is the airport you will fly out of if you book a flight from Columbia to North Carolina. It is only a 11.1 mi journey to Columbia Regional (COU) from Columbia’s city center.

  • How long is the flight from Columbia, Missouri to North Carolina?

    A quick flight from Columbia, Missouri to North Carolina can take about 6h 12m. United Airlines provides one of the quickest options available for as low as $400. The distance between Columbia, Missouri and North Carolina is about 669 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbia, Missouri to North Carolina?

    The most popular flight routes from Columbia, Missouri to North Carolina are Columbia Regional - Charlotte Douglas, Columbia Regional - Knoxville McGhee Tyson and Columbia Regional - Myrtle Beach Intl.

  • Can I find deals for flights from Columbia to North Carolina that include hotel bookings?

    Yes. In addition to deals on Columbia to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to North Carolina.

  • Can I find deals for business class flights from Columbia to North Carolina?

    Yes. Cheapflights offers flight deals from Columbia to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbia to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Las Vegas flights
St. Louis to LaGuardia flights
St. Louis to Newark flights
Kansas City to Las Vegas flights
Kansas City to John F Kennedy Intl flights
St. Louis to John F Kennedy Intl flights
Kansas City to Dallas/Fort Worth flights
Kansas City to LaGuardia flights
Kansas City to Los Angeles flights
Kansas City to Denver flights
St. Louis to Denver flights
St. Louis to Orlando flights
St. Louis to Sky Harbor Intl flights
Kansas City to Newark flights
St. Louis to Atlanta flights
Kansas City to Atlanta flights
Kansas City to Orlando flights
St. Louis to Miami flights
Kansas City to O'Hare Intl flights
St. Louis to Hobby flights
St. Louis to Dallas/Fort Worth flights
St. Louis to Los Angeles flights
Kansas City to Seattle flights
Kansas City to Sky Harbor Intl flights
Kansas City to Miami flights
St. Louis to Dulles Intl flights
Kansas City to Hobby flights
Kansas City to Dulles Intl flights
St. Louis to George Bush Intcntl flights
Kansas City to Fort Lauderdale flights
St. Louis to Boston flights
St. Louis to Fort Lauderdale flights
St. Louis to O'Hare Intl flights
Kansas City to Midway flights
Kansas City to George Bush Intcntl flights
Kansas City to Reagan-National flights
St. Louis to New Orleans flights
Kansas City to Tampa flights
St. Louis to Baltimore flights
St. Louis to Tampa flights
Kansas City to Ontario flights
St. Louis to San Diego flights
Kansas City to Nashville flights
St. Louis to Seattle flights
St. Louis to San Francisco flights
St. Louis to Detroit flights
St. Louis to Honolulu flights
Kansas City to Baltimore flights
St. Louis to Reagan-National flights
Kansas City to Boston flights

Top airline flying from Columbia to North Carolina

Discover the top airline that operate flights from Columbia to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$320Average$458FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.