HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Myrtle Beach

$97+ Cheap flights from Missouri to Myrtle Beach (MYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MYR
nov. 27 — dic. 41
jue. 11/27
jue. 12/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Myrtle Beach with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Myrtle Beach

Keep the following information in mind while searching for Missouri to Myrtle Beach flight deals. Data was last updated octubre 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$236
(Kiwi.com)

One-way from

$97
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$359
Provider with most accurate pricing for Lambert-St Louis-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Myrtle Beach Intl flights.
Search Deals
From Missouri to Myrtle Beach Intl
Search Deals
One-way flight from Missouri to Myrtle Beach Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Missouri to Myrtle Beach

Cheapest flights from Missouri to Myrtle Beach
Explore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/246:00 amMCI - MYR
1 stop13h 03mSpirit Airlines
jue. 11/276:15 amMYR - MCI
1 stop6h 48mSpirit Airlines
Deal found 10/27$236
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2010:53 amSTL - MYR
1 stop12h 01mMultiple Airlines
lun. 11/246:15 amMYR - STL
2 stops13h 04mMultiple Airlines
Deal found 10/26$249
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/236:00 amMCI - MYR
1 stop13h 03mSpirit Airlines
jue. 11/276:15 amMYR - MCI
1 stop6h 48mSpirit Airlines
Deal found 10/27$256
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/37:43 pmSTL - MYR
2 stops22h 49mMultiple Airlines
sáb. 12/62:15 pmMYR - STL
1 stop9h 18mMultiple Airlines
Deal found 10/27$260
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/112:47 pmSTL - MYR
1 stop26h 01mMultiple Airlines
lun. 12/152:15 pmMYR - STL
1 stop9h 18mMultiple Airlines
Deal found 10/27$280
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:01 pmMCI - MYR
2 stops17h 19mSpirit Airlines
dom. 12/148:27 pmMYR - MCI
2 stops22h 29mSpirit Airlines
Deal found 10/26$299
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/246:00 amMCI - MYR
1 stop13h 03mSpirit Airlines
lun. 12/18:59 pmMYR - MCI
2 stops16h 04mSpirit Airlines
Deal found 10/27$306
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1212:13 pmMCI - MYR
2 stops18h 47mMultiple Airlines
dom. 12/148:27 pmMYR - MCI
1 stop27h 48mMultiple Airlines
Deal found 10/26$309
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/233:41 pmSTL - MYR
1 stop3h 49mDelta
mié. 12/3111:09 amMYR - STL
1 stop6h 19mDelta
Deal found 10/28$325
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/186:15 pmMCI - MYR
1 stop22h 53mMultiple Airlines
mar. 12/239:54 amMYR - MCI
2 stops25h 14mMultiple Airlines
Deal found 10/26$326
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1010:25 amSTL - MYR
1 stop8h 03mMultiple Airlines
sáb. 11/156:15 amMYR - STL
2 stops27h 52mMultiple Airlines
Deal found 10/26$333
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/108:05 amMCI - MYR
1 stop4h 50mDelta
mié. 12/172:40 pmMYR - MCI
1 stop7h 28mDelta
Deal found 10/27$335

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
Use the filters below to find and compare flights from Missouri to Myrtle Beach that are best for you.

Fly from

Missouri

Fly to

Myrtle Beach

Route

Depart

Return

Price

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

dom. 11/23

6:00 am-8:03 pm

1 stop13h 03m

Myrtle Beach Intl

jue. 11/27

6:15 am-12:03 pm

1 stop6h 48m

$256

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

lun. 11/24

6:00 am-11:54 pm

2 stops16h 54m

Myrtle Beach Intl

jue. 11/27

6:15 am-12:03 pm

1 stop6h 48m

$257

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

mié. 12/3

3:30 pm-7:32 pm

1 stop27h 02m

Myrtle Beach Intl

sáb. 12/6

2:15 pm-10:33 pm

1 stop9h 18m

$267

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

jue. 11/20

10:53 am-11:54 pm

1 stop12h 01m

Myrtle Beach Intl

lun. 11/24

6:15 am-6:19 pm

2 stops13h 04m

$272

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

jue. 12/11

2:47 pm-5:48 pm

1 stop26h 01m

Myrtle Beach Intl

lun. 12/15

2:15 pm-10:33 pm

1 stop9h 18m

$280

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

mié. 1/28

5:11 pm-7:35 pm

1 stop25h 24m

Myrtle Beach Intl

dom. 2/1

8:30 pm-7:50 am

1 stop12h 20m

$296

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

vie. 12/12

7:01 pm-1:20 pm

2 stops17h 19m

Myrtle Beach Intl

dom. 12/14

8:27 pm-5:56 pm

2 stops22h 29m

$299

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

jue. 12/18

9:30 am-1:54 pm

1 stop3h 24m

Myrtle Beach Intl

mar. 12/23

6:59 pm-11:42 pm

1 stop5h 43m

$325

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

mar. 12/23

3:41 pm-8:30 pm

1 stop3h 49m

Myrtle Beach Intl

mié. 12/31

11:09 am-4:28 pm

1 stop6h 19m

$325

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

jue. 1/29

7:10 am-1:32 pm

1 stop5h 22m

Myrtle Beach Intl

lun. 2/2

2:19 pm-5:50 pm

1 stop4h 31m

$325

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 38 results
1
2
3
4

Best time to book a flight from Missouri to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Myrtle Beach

What is the cheapest month to book a flight from Missouri to Myrtle Beach?

Currently, February is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $84). Flying from Missouri to Myrtle Beach in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MYR?

Find hourly flight availability from Missouri to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 28, 2025.

It’s typically best to fly out from Missouri to Myrtle Beach in the evening. Doing so could potentially save you 39% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to Myrtle Beach?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Myrtle Beach. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Myrtle Beach flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Myrtle Beach from Missouri?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly into when you book flights from Missouri to Myrtle Beach.

  • How popular is this Missouri to Myrtle Beach flight route?

    This flight path from Missouri to Myrtle Beach Intl was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Myrtle Beach?

    A quick flight from Missouri to Myrtle Beach can take about 6h 15m. Spirit Airlines provides one of the quickest options available for as low as $335. Airlines will cover a distance of 957 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Missouri to Myrtle Beach?

    Most travelers choose Lambert-St Louis - Myrtle Beach Intl, Kansas City - Myrtle Beach Intl or Springfield-Branson - Myrtle Beach Intl when deciding on the best route from Missouri to Myrtle Beach.

  • Can I find deals for flights from Missouri to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Missouri to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Myrtle Beach.

  • Can I find deals for business class flights from Missouri to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Missouri to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Myrtle Beach?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $84). Flying from Missouri to Myrtle Beach in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Conway
Surfside Beach
Little River
Pawleys Island
Ocean Isle Beach
Garden City Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Myrtle Beach

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
Newark to Charlotte flights
LaGuardia to Charlotte flights
Boston to Charlotte flights
John F Kennedy Intl to Savannah flights
LaGuardia to Charleston flights
Dallas/Fort Worth to Charlotte flights
John F Kennedy Intl to Charleston flights
Newark to Charleston flights
O'Hare Intl to Charlotte flights
Boston to Charleston flights
Denver to Charlotte flights
Dulles Intl to Charlotte flights
O'Hare Intl to Charleston flights
Hobby to Charlotte flights
Dulles Intl to Charleston flights
Baltimore to Charlotte flights
Newark to Savannah flights
George Bush Intcntl to Charlotte flights
Newark to Myrtle Beach flights
Boston to Savannah flights
LaGuardia to Savannah flights
LaGuardia to Greenville flights
Newark to Greenville flights
LaGuardia to Myrtle Beach flights
Minneapolis to Charlotte flights
John F Kennedy Intl to Myrtle Beach flights
Los Angeles to Charlotte flights
Philadelphia to Charleston flights
Philadelphia to Charlotte flights
Fort Lauderdale to Charlotte flights
Baltimore to Charleston flights
Reagan-National to Charlotte flights
Orlando to Charlotte flights
O'Hare Intl to Savannah flights
Minneapolis to Charleston flights
Cleveland to Charlotte flights
John F Kennedy Intl to Greenville flights
Providence to Charleston flights
San Francisco to Charlotte flights
Seattle to Charlotte flights
Detroit to Charlotte flights
Philadelphia to Savannah flights
Reagan-National to Charleston flights
Denver to Savannah flights
Denver to Charleston flights
Detroit to Charleston flights
LaGuardia to Columbia flights
Baltimore to Savannah flights
Love Field to Charlotte flights

Top 4 airlines flying from Missouri to Myrtle Beach

Discover the top 4 airlines that operate flights from Missouri to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$84Average$220FlexibilityNo cancel feeOn-time65%
DeltaCheapest$150Average$396FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$204Average$397FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$283Average$398FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.