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Myrtle Beach

$79+ Cheap flights from Missouri to Myrtle Beach (MYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MYR
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from Missouri to Myrtle Beach

Cheapest flights from Missouri to Myrtle Beach
Explore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/176:49 pmSGF - MYR
1 stop3h 54mDelta
dom. 12/211:18 pmMYR - SGF
1 stop4h 05mDelta
Deal found 12/9$339
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/177:00 amSGF - MYR
2 stops6h 44mAmerican Airlines
dom. 12/216:00 amMYR - SGF
1 stop5h 59mAmerican Airlines
Deal found 12/9$344
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:02 amSTL - MYR
1 stop5h 05mAmerican Airlines
mar. 1/610:18 amMYR - STL
1 stop5h 46mAmerican Airlines
Deal found 12/11$388
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/171:25 pmSGF - MYR
1 stop6h 25mAmerican Airlines
sáb. 12/206:00 amMYR - SGF
2 stops10h 12mAmerican Airlines
Deal found 12/9$433
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/186:25 pmSGF - MYR
1 stop4h 30mAmerican Airlines
dom. 12/216:00 amMYR - SGF
2 stops10h 12mAmerican Airlines
Deal found 12/9$436
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/236:35 pmSTL - MYR
1 stop4h 20mAmerican Airlines
mié. 12/315:11 amMYR - STL
1 stop4h 24mAmerican Airlines
Deal found 12/11$443
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/236:35 pmSTL - MYR
1 stop4h 20mAmerican Airlines
sáb. 1/37:46 pmMYR - STL
1 stop5h 10mAmerican Airlines
Deal found 12/9$457
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:01 pmMCI - MYR
1 stop21h 47mMultiple Airlines
jue. 12/182:59 pmMYR - MCI
2 stops27h 11mMultiple Airlines
Deal found 12/10$458
This Southwest deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/258:25 amSTL - MYR
1 stop4h 50mSouthwest
vie. 1/27:00 amMYR - STL
2 stops8h 25mSouthwest
Deal found 12/9$462
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/2110:57 amSTL - MYR
2 stops20h 47mMultiple Airlines
jue. 1/17:32 pmMYR - STL
1 stop15h 13mMultiple Airlines
Deal found 12/10$466
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:01 pmMCI - MYR
1 stop21h 47mSpirit Airlines
jue. 12/189:54 amMYR - MCI
1 stop8h 16mSpirit Airlines
Deal found 12/10$477
This Southwest deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:45 amSTL - MYR
1 stop4h 20mSouthwest
vie. 1/27:00 amMYR - STL
2 stops8h 25mSouthwest
Deal found 12/11$482

Find flight deals from Missouri to Myrtle Beach

Keep the following information in mind while searching for Missouri to Myrtle Beach flight deals. Data was last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$207
(Kiwi.com)

One-way from

$79
(Super.com)

Popular in

March

Cheapest in

July

Average price

$448
Provider with most accurate pricing for Lambert-St Louis-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Myrtle Beach Intl flights.
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From Missouri to Myrtle Beach Intl
Search Deals
One-way flight from Missouri to Myrtle Beach Intl
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($19 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Missouri to Myrtle Beach that are best for you.

Fly from

Missouri

Fly to

Myrtle Beach

Route

Depart

Return

Price

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

lun. 1/19

5:11 pm-12:12 pm

1 stop18h 01m

Myrtle Beach Intl

mar. 1/27

10:00 am-6:51 am

2 stops21h 51m

$207

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

jue. 1/8

3:43 pm-2:42 pm

2 stops21h 59m

Myrtle Beach Intl

jue. 1/15

1:07 pm-7:54 am

1 stop19h 47m

$232

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

sáb. 1/10

5:04 pm-12:12 pm

1 stop18h 08m

Myrtle Beach Intl

sáb. 1/17

8:15 pm-10:31 am

1 stop15h 16m

$274

SpringfieldMyrtle Beach

SGF - MYR

SGFMYR

Springfield-Branson

sáb. 1/24

10:50 am-5:04 pm

1 stop5h 14m

Myrtle Beach Intl

jue. 1/29

6:23 am-12:15 pm

1 stop6h 52m

$286

SpringfieldMyrtle Beach

SGF - MYR

SGFMYR

Springfield-Branson

sáb. 1/24

8:18 am-1:23 pm

1 stop4h 05m

Myrtle Beach Intl

dom. 1/25

5:29 pm-9:00 pm

1 stop4h 31m

$294

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

jue. 2/19

11:26 am-8:15 am

1 stop19h 49m

Myrtle Beach Intl

dom. 2/22

9:10 am-10:30 am

1 stop26h 20m

$298

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

mar. 3/3

6:30 am-12:11 pm

1 stop4h 41m

Myrtle Beach Intl

mié. 3/4

4:00 pm-8:41 pm

1 stop5h 41m

$333

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

mar. 3/3

6:00 am-5:03 pm

2 stops10h 03m

Myrtle Beach Intl

mié. 3/4

5:38 pm-10:51 pm

1 stop6h 13m

$338

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

mié. 2/18

6:35 am-12:11 pm

1 stop4h 36m

Myrtle Beach Intl

sáb. 2/21

1:10 pm-4:42 pm

1 stop4h 32m

$345

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

mié. 2/18

6:00 am-1:26 pm

2 stops6h 26m

Myrtle Beach Intl

sáb. 2/21

6:38 pm-11:02 pm

1 stop5h 24m

$350

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 50 results
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Best time to book a flight from Missouri to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Myrtle Beach

What is the cheapest month to book a flight from Missouri to Myrtle Beach?

Currently, February is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $84). Flying from Missouri to Myrtle Beach in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MYR?

Find hourly flight availability from Missouri to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

It’s typically best to fly out from Missouri to Myrtle Beach in the evening. Doing so could potentially save you 39% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to Myrtle Beach?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Myrtle Beach. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Myrtle Beach flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Myrtle Beach from Missouri?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly into when you book flights from Missouri to Myrtle Beach.

  • How popular is this Missouri to Myrtle Beach flight route?

    This flight path from Missouri to Myrtle Beach Intl was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Myrtle Beach?

    A quick flight from Missouri to Myrtle Beach can take about 4h 41m. Spirit Airlines provides one of the quickest options available for as low as $333. Airlines will cover a distance of 957 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Missouri to Myrtle Beach?

    Most travelers choose Kansas City - Myrtle Beach Intl, Lambert-St Louis - Myrtle Beach Intl or Springfield-Branson - Myrtle Beach Intl when deciding on the best route from Missouri to Myrtle Beach.

  • Can I find deals for flights from Missouri to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Missouri to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Myrtle Beach.

  • Can I find deals for business class flights from Missouri to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Missouri to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Myrtle Beach?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $84). Flying from Missouri to Myrtle Beach in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Conway
Surfside Beach
Little River
Pawleys Island
Ocean Isle Beach
Garden City Beach

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Top 4 airlines flying from Missouri to Myrtle Beach

Discover the top 4 airlines that operate flights from Missouri to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$84Average$216FlexibilityNo cancel feeOn-time65%
DeltaCheapest$150Average$395FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$204Average$396FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$274Average$396FlexibilityNo cancel feeOn-time63%

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