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Myrtle Beach

$98+ Cheap flights from Missouri to Myrtle Beach (MYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MYR
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Missouri to Myrtle Beach

Keep the following information in mind while searching for Missouri to Myrtle Beach flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$219
(American Airlines)

One-way from

$98
(Southwest)

Popular in

March

Cheapest in

November

Average price

$346
From Missouri to Myrtle Beach Intl
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One-way flight from Missouri to Myrtle Beach Intl
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Highest demand for flights based on searches. 7% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Missouri to Myrtle Beach

Cheapest flights from Missouri to Myrtle Beach
Explore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/158:43 amSTL - MYR
1 stop5h 40mAmerican Airlines
sáb. 11/228:07 pmMYR - STL
1 stop4h 58mAmerican Airlines
Deal found 9/10$219
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/256:15 pmMCI - MYR
1 stop4h 44mDelta
sáb. 11/14:00 pmMYR - MCI
1 stop6h 08mDelta
Deal found 9/10$227
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/256:15 pmMCI - MYR
1 stop4h 44mDelta
mar. 11/46:00 amMYR - MCI
1 stop4h 13mDelta
Deal found 9/10$229
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/2112:36 pmMCI - MYR
1 stop4h 27mDelta
mar. 11/42:35 pmMYR - MCI
1 stop7h 33mDelta
Deal found 9/10$231
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/12:11 pmSTL - MYR
1 stop5h 58mAmerican Airlines
mar. 10/712:30 pmMYR - STL
1 stop4h 40mAmerican Airlines
Deal found 9/9$233
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/146:15 amMCI - MYR
1 stop4h 13mAmerican Airlines
mar. 10/216:00 amMYR - MCI
2 stops7h 54mAmerican Airlines
Deal found 9/11$236
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/58:13 amSTL - MYR
1 stop5h 33mAmerican Airlines
lun. 11/107:41 pmMYR - STL
1 stop4h 26mAmerican Airlines
Deal found 9/9$240
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/253:55 pmMCI - MYR
1 stop7h 04mDelta
jue. 10/306:00 amMYR - MCI
1 stop4h 13mDelta
Deal found 9/10$241
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/204:39 pmMCI - MYR
1 stop6h 20mDelta
mar. 11/410:36 amMYR - MCI
1 stop7h 08mDelta
Deal found 9/10$243
This Cheapflightsfares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/255:15 amMCI - MYR
1 stop10h 10mSpirit Airlines
jue. 10/25:20 pmMYR - MCI
1 stop6h 47mSpirit Airlines
Deal found 9/9$246
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/114:25 pmSTL - MYR
1 stop6h 34mAmerican Airlines
sáb. 10/184:47 pmMYR - STL
1 stop7h 31mAmerican Airlines
Deal found 9/11$247
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/512:03 pmMCI - MYR
2 stops9h 33mAmerican Airlines
lun. 11/104:00 pmMYR - MCI
1 stop8h 05mAmerican Airlines
Deal found 9/9$248

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Missouri to Myrtle Beach that are best for you.

Fly from

Missouri

Fly to

Myrtle Beach

Route

Depart

Return

Price

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

sáb. 11/15

2:08 pm-7:22 pm

1 stop4h 14m

Myrtle Beach Intl

sáb. 11/22

5:03 am-8:27 am

1 stop4h 24m

$219

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

sáb. 10/25

6:15 pm-11:59 pm

1 stop4h 44m

Myrtle Beach Intl

sáb. 11/1

4:00 pm-9:08 pm

1 stop6h 08m

$227

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

sáb. 10/25

9:00 am-3:08 pm

1 stop5h 08m

Myrtle Beach Intl

mié. 10/29

11:29 am-5:06 pm

1 stop6h 37m

$229

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

sáb. 10/25

6:15 pm-11:59 pm

1 stop4h 44m

Myrtle Beach Intl

mar. 11/4

6:00 am-9:13 am

1 stop4h 13m

$229

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

mar. 10/21

12:36 pm-6:03 pm

1 stop4h 27m

Myrtle Beach Intl

mar. 11/4

2:35 pm-9:08 pm

1 stop7h 33m

$231

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

mar. 10/21

10:18 am-6:03 pm

1 stop6h 45m

Myrtle Beach Intl

mié. 10/29

2:35 pm-7:01 pm

1 stop5h 26m

$231

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

mié. 10/22

4:39 pm-11:59 pm

1 stop6h 20m

Myrtle Beach Intl

mié. 10/29

2:35 pm-7:01 pm

1 stop5h 26m

$231

Kansas CityMyrtle Beach

MCI - MYR

MCIMYR

Kansas City

mié. 10/22

12:36 pm-6:03 pm

1 stop4h 27m

Myrtle Beach Intl

mar. 11/4

2:35 pm-9:08 pm

1 stop7h 33m

$231

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

mié. 10/29

7:00 am-4:03 pm

1 stop8h 03m

Myrtle Beach Intl

mié. 11/5

3:32 pm-6:25 pm

1 stop3h 53m

$233

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

mié. 10/1

2:11 pm-9:09 pm

1 stop5h 58m

Myrtle Beach Intl

mar. 10/7

12:30 pm-4:10 pm

1 stop4h 40m

$233

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 50 results
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Best time to book a flight from Missouri to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Myrtle Beach

What is the cheapest month to book a flight from Missouri to Myrtle Beach?

Currently, May is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $196). Flying from Missouri to Myrtle Beach in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MYR?

Find hourly flight availability from Missouri to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Myrtle Beach as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Myrtle Beach from Missouri?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly into when you book flights from Missouri to Myrtle Beach.

  • How popular is this Missouri to Myrtle Beach flight route?

    This flight path from Missouri to Myrtle Beach Intl was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Myrtle Beach?

    A quick flight from Missouri to Myrtle Beach can take about 4h 14m. American Airlines provides one of the quickest options available for as low as $219. Airlines will cover a distance of 727 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Myrtle Beach one-way?

    The cheapest airlines for a one-way flight from Missouri to Myrtle Beach are Southwest ($98), Spirit Airlines ($109), and Delta ($110).

  • What are the most popular routes from Missouri to Myrtle Beach?

    Most travelers choose Lambert-St Louis - Myrtle Beach Intl, Kansas City - Myrtle Beach Intl or Springfield-Branson - Myrtle Beach Intl when deciding on the best route from Missouri to Myrtle Beach.

  • Can I find deals for flights from Missouri to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Missouri to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Myrtle Beach.

  • Can I find deals for business class flights from Missouri to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Missouri to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Myrtle Beach?

    Currently, May is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $196). Flying from Missouri to Myrtle Beach in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Conway
Surfside Beach
Little River
Pawleys Island
Ocean Isle Beach
Garden City Beach

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Top 4 airlines flying from Missouri to Myrtle Beach

Discover the top 4 airlines that operate flights from Missouri to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$99Average$218FlexibilityNo cancel feeOn-time65%
DeltaCheapest$150Average$396FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$204Average$397FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$286Average$397FlexibilityNo cancel feeOn-time63%

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