In terms of precipitation, rainfall in Florence, Alabama ranges from 2.9 - 6.1 inches per month. March is typically the wettest month, when rainfall can reach 6.1 in. October is typically the driest time to visit Florence, Alabama when rainfall is around 2.9 in.

If weather is an important factor for your trip to Florence, Alabama, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest time of day to fly from CO to MSL?

When flying from Colorado to Florence, Alabama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly into for flights to Florence from Colorado?

Florence Muscle Shoals (MSL) is the airport you will fly into if you book a flight from Colorado to Florence. It is only a 5.4 mi journey from Muscle Shoals (MSL) to Florence’s city center.

Can I find deals for flights from Colorado to Florence that include hotel bookings?

Yes. In addition to deals on Colorado to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Colorado to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Florence.

Can I find deals for business class flights from Colorado to Florence?

Yes. Cheapflights offers flight deals from Colorado to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$428+ Cheap Flights from Colorado to Florence, AL

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Cheap flight deals from Colorado to Florence

Round-trip from	$428 (Kiwi.com)

From Colorado to Florence Muscle Shoals

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Cheapest flights from Colorado to Florence
Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

vie. 10/1011:45 pmDEN - MSL

2 stops11h 15mMultiple Airlines

vie. 10/177:25 amMSL - DEN

1 stop13h 01mMultiple Airlines

Deal found 9/10

$428

Best flights from Colorado to Florence
Discover carefully curated flight deals from Colorado to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated septiembre 11, 2025.

vie. 10/1011:20 amDEN - MSL

1 stop6h 50mMultiple Airlines

vie. 10/177:25 amMSL - DEN

1 stop13h 01mMultiple Airlines

Deal found 9/10

$475

Last-minute flights from Colorado to Florence
Discover last-minute flight deals from Colorado to Florence. Data last updated septiembre 11, 2025 and is based on user searches.

vie. 10/1011:45 pmDEN - MSL

2 stops11h 15mMultiple Airlines

vie. 10/177:25 amMSL - DEN

1 stop13h 01mMultiple Airlines

Deal found 9/10

$428

Cheapflights Fare Finder

Use the filters below to find and compare flights from Colorado to Florence that are best for you.

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Route

Depart

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DenverFlorence

DEN - MSL

DENMSL

Denver Intl

vie. 10/10

11:20 am-7:10 pm

1 stop6h 50m

Florence Muscle Shoals

vie. 10/17

7:25 am-7:26 pm

1 stop13h 01m

$475

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Colorado to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Colorado with our price prediction graph.

Estimated round-trip price

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Everything you need to know about your flight from Colorado to Florence

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Related info for your journey

What airport do you fly into for flights to Florence from Colorado?
Florence Muscle Shoals (MSL) is the airport you will fly into if you book a flight from Colorado to Florence. It is only a 5.4 mi journey from Muscle Shoals (MSL) to Florence’s city center.
Can I find deals for flights from Colorado to Florence that include hotel bookings?
Yes. In addition to deals on Colorado to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Colorado to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Florence.
Can I find deals for business class flights from Colorado to Florence?
Yes. Cheapflights offers flight deals from Colorado to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Sheffield

Muscle Shoals

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$428+ Cheap flights from Colorado to Florence, AL (MSL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Colorado to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Colorado to Florence

Keep the following information in mind while searching for Colorado to Florence flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

Find flight deals from Colorado to Florence

Cheapest flights from Colorado to FlorenceExplore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Colorado to Florence that are best for you.

Best time to book a flight from Colorado to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Colorado with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Florence

Related info for your journey

Find useful and relevant information for your journey from Colorado to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Florence from Colorado?

Can I find deals for flights from Colorado to Florence that include hotel bookings?

How can I find direct flights from Colorado to Florence?

Can I find deals for business class flights from Colorado to Florence?

Traveling to a place near Florence?

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Alternative routes for Colorado to Florence

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Cheapest flights from Colorado to Florence
Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.