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Missouri

$148+ Cheap flights from Syracuse (SYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — STL
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Syracuse to Missouri

Keep the following information in mind while searching for Syracuse to Missouri flight deals. Data was last updated June 12, 2025.

Round-trip from

$249
(Delta)

One-way from

$148
(Mytrip)

Popular in

May

Cheapest in

February

Average price

$336
From Syracuse Hancock Intl to Missouri
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One-way flight from Syracuse Hancock Intl to Missouri
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Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Syracuse to Missouri

Cheapest flights from Syracuse to Missouri
Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2112:10 pmSYR - STL
1 stop4h 56mDelta
Wed 8/276:00 amSTL - SYR
1 stop4h 45mDelta
Deal found 6/11$249
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/86:49 pmSYR - STL
1 stop5h 18mAmerican Airlines
Sat 9/135:55 amSTL - SYR
2 stops7h 55mAmerican Airlines
Deal found 6/12$254
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:20 amSYR - SGF
1 stop6h 15mAmerican Airlines
Mon 9/16:18 pmSGF - SYR
1 stop4h 55mAmerican Airlines
Deal found 6/11$255
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:50 pmSYR - MCI
1 stop6h 07mDelta
Sun 12/72:55 pmMCI - SYR
1 stop8h 00mDelta
Deal found 6/9$259
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/122:38 pmSYR - MCI
2 stops8h 07mAmerican Airlines
Sun 8/176:33 pmMCI - SYR
1 stop4h 42mAmerican Airlines
Deal found 6/12$287
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/308:34 pmSYR - STL
1 stop20h 57mMultiple Airlines
Sun 8/310:47 amSTL - SYR
2 stops21h 09mMultiple Airlines
Deal found 6/10$292
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2411:46 amSYR - MCI
1 stop23h 46mSun Country Air
Sun 7/275:20 pmMCI - SYR
1 stop15h 24mSun Country Air
Deal found 6/10$296
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:00 amSYR - STL
2 stops9h 27mUnited Airlines
Wed 10/155:24 pmSTL - SYR
1 stop4h 51mUnited Airlines
Deal found 6/11$315
This FlightHub deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/218:41 pmSYR - STL
1 stop28h 06mFrontier
Sun 7/272:36 pmSTL - SYR
1 stop20h 15mFrontier
Deal found 6/10$330
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/238:34 pmSYR - MCI
2 stops19h 43mMultiple Airlines
Sun 7/275:20 pmMCI - SYR
1 stop15h 24mMultiple Airlines
Deal found 6/10$343
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/265:40 pmSYR - MCI
1 stop6h 34mUnited Airlines
Mon 6/305:40 pmMCI - SYR
1 stop5h 19mUnited Airlines
Deal found 6/11$359
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:51 amSYR - COU
1 stop4h 22mAmerican Airlines
Sun 11/95:59 amCOU - SYR
1 stop3h 48mAmerican Airlines
Deal found 6/10$507

Cheapflights Fare Finder

Customize your flight search to find flights from Syracuse to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Syracuse to Missouri that are best for you.

Fly from

Syracuse

Fly to

Missouri

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 8/21

12:10 pm-4:06 pm

1 stop4h 56m

Lambert-St Louis

Fri 8/29

3:42 pm-11:51 pm

1 stop7h 09m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Mon 9/8

6:49 pm-11:07 pm

1 stop5h 18m

Lambert-St Louis

Sat 9/13

5:55 am-2:50 pm

2 stops7h 55m

$254

SyracuseSpringfield

SYR - SGF

SYRSGF

Syracuse Hancock Intl

Wed 8/27

6:20 am-11:35 am

1 stop6h 15m

Springfield-Branson

Mon 9/1

6:18 pm-12:13 am

1 stop4h 55m

$255

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Tue 8/12

4:47 pm-10:54 pm

1 stop7h 07m

Kansas City

Sun 8/17

6:33 pm-12:15 am

1 stop4h 42m

$259

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 6/25

5:50 am-12:08 pm

1 stop7h 18m

Kansas City

Sun 6/29

6:30 am-11:55 am

1 stop4h 25m

$289

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 7/30

8:34 pm-4:31 pm

1 stop20h 57m

Lambert-St Louis

Sun 8/3

10:47 am-8:56 am

2 stops21h 09m

$292

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Thu 7/24

11:46 am-10:32 am

1 stop23h 46m

Kansas City

Sun 7/27

5:20 pm-9:44 am

1 stop15h 24m

$296

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 10/8

6:00 am-2:27 pm

2 stops9h 27m

Lambert-St Louis

Wed 10/15

5:24 pm-11:15 pm

1 stop4h 51m

$315

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Mon 7/21

8:41 pm-11:47 pm

1 stop28h 06m

Lambert-St Louis

Sun 7/27

2:36 pm-11:51 am

1 stop20h 15m

$330

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 7/23

8:34 pm-3:17 pm

2 stops19h 43m

Kansas City

Sun 7/27

5:20 pm-9:44 am

1 stop15h 24m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 28 results
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Best time to book a flight from Syracuse to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Missouri

What is the cheapest month to book a flight from Syracuse to Missouri?

Currently, August is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $311). Flying from Syracuse to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to MO?

Find hourly flight availability from Syracuse to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Syracuse to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 12, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and American Airlines from Syracuse to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Sun Country Air
6.9
Okay
345 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Frontier
5.9
Fair
3,295 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Missouri?

    If you book a flight to Missouri from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • What are the cheapest airlines to fly from Syracuse to Missouri one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $198. Users have also found prices from $223 and $226 on Delta and American Airlines, respectively.

  • What are the most popular routes from Syracuse to Missouri?

    Most travelers choose Syracuse Hancock Intl - Kansas City, Syracuse Hancock Intl - Lambert-St Louis or Syracuse Hancock Intl - Springfield-Branson when deciding on the best route from Syracuse to Missouri.

  • Can I find deals for flights from Syracuse to Missouri that include hotel bookings?

    Yes. In addition to deals on Syracuse to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Missouri.

  • Can I find deals for business class flights from Syracuse to Missouri?

    Yes. Cheapflights offers flight deals from Syracuse to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $311). Flying from Syracuse to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Syracuse to Missouri

Discover the top 3 airlines that operate flights from Syracuse to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$453FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$238Average$491FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$372FlexibilityNo cancel feeOn-timeN/A

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