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Missouri

$162+ Cheap flights from Syracuse (SYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — STL
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Syracuse to Missouri

Cheapest flights from Syracuse to Missouri
Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:34 am
SYR
-
STL
1 stop7h 37m
American Airlines
Sat 8/226:20 am
STL
-
SYR
1 stop4h 45m
American Airlines
Deal found 2/9$251
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:15 pm
SYR
-
STL
1 stop4h 39m
American Airlines
Tue 6/26:15 am
STL
-
SYR
1 stop7h 17m
American Airlines
Deal found 2/9$260
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:55 am
SYR
-
STL
1 stop5h 02m
Delta
Mon 9/143:42 pm
STL
-
SYR
1 stop7h 16m
Delta
Deal found 2/12$269
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:55 am
SYR
-
STL
1 stop5h 02m
Delta
Sun 8/305:00 pm
STL
-
SYR
1 stop5h 57m
Delta
Deal found 2/9$270
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
SYR
-
MCI
1 stop4h 49m
Delta
Sat 4/186:30 am
MCI
-
SYR
1 stop4h 45m
Delta
Deal found 2/9$279
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:15 am
SYR
-
MCI
1 stop7h 46m
American Airlines
Tue 3/246:00 am
MCI
-
SYR
2 stops8h 35m
American Airlines
Deal found 2/9$284
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:27 pm
SYR
-
STL
1 stop4h 38m
United Airlines
Sat 2/288:17 am
STL
-
SYR
2 stops10h 57m
United Airlines
Deal found 2/9$284
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:18 am
SYR
-
STL
1 stop6h 36m
Delta
Mon 7/139:00 am
STL
-
SYR
1 stop6h 21m
Delta
Deal found 2/12$285
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:59 pm
SYR
-
MCI
1 stop5h 50m
Delta
Tue 5/265:12 pm
MCI
-
SYR
1 stop5h 40m
Delta
Deal found 2/9$289
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:15 pm
SYR
-
STL
1 stop5h 37m
Delta
Sat 2/285:50 pm
STL
-
SYR
1 stop4h 23m
Delta
Deal found 2/9$289
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:01 pm
SYR
-
STL
1 stop6h 17m
American Airlines
Sun 8/236:06 am
STL
-
SYR
1 stop4h 34m
American Airlines
Deal found 2/11$290
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:12 am
SYR
-
MCI
1 stop5h 36m
American Airlines
Sun 4/193:28 pm
MCI
-
SYR
1 stop6h 42m
American Airlines
Deal found 2/9$291

Find flight deals from Syracuse to Missouri

Keep the following information in mind while searching for Syracuse to Missouri flight deals. Data was last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$260
(American Airlines)

One-way from

$162
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$313
Provider with most accurate pricing for Syracuse Hancock Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Lambert-St Louis flights.
Search Deals
From Syracuse Hancock Intl to Missouri
Search Deals
One-way flight from Syracuse Hancock Intl to Missouri
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Syracuse to Missouri that are best for you.

Fly from

Syracuse

Fly to

Missouri

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 5/28

6:10 am-10:37 am

1 stop5h 27m

Lambert-St Louis

Tue 6/2

6:15 am-2:32 pm

1 stop7h 17m

$260

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Tue 3/24

5:29 pm-9:59 pm

1 stop5h 30m

Kansas City

Sat 3/28

5:40 pm-11:44 pm

1 stop5h 04m

$279

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Fri 5/22

5:00 pm-10:36 pm

1 stop6h 36m

Kansas City

Wed 5/27

5:48 pm-11:14 pm

1 stop4h 26m

$279

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Thu 4/16

10:12 am-2:48 pm

1 stop5h 36m

Kansas City

Sat 4/18

3:28 pm-9:33 pm

1 stop5h 05m

$279

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Fri 5/8

6:15 am-10:33 am

1 stop5h 18m

Kansas City

Sat 5/9

5:40 pm-11:41 pm

1 stop5h 01m

$279

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 4/29

6:30 am-10:27 am

1 stop4h 57m

Kansas City

Sat 5/2

3:22 pm-8:43 pm

1 stop4h 21m

$279

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Sat 5/2

5:40 am-10:18 am

1 stop5h 38m

Kansas City

Mon 5/4

3:28 pm-11:27 pm

1 stop6h 59m

$279

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Thu 3/12

5:15 am-12:01 pm

1 stop7h 46m

Kansas City

Tue 3/24

6:00 am-3:35 pm

2 stops8h 35m

$284

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 2/24

5:27 pm-9:05 pm

1 stop4h 38m

Lambert-St Louis

Sat 2/28

8:17 am-8:14 pm

2 stops10h 57m

$284

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 3/5

5:50 am-9:32 am

1 stop4h 42m

Lambert-St Louis

Mon 3/9

5:59 pm-11:09 pm

1 stop4h 10m

$296

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/9

Showing 1-10 of 45 results
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Best time to book a flight from Syracuse to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Missouri

What is the cheapest month to book a flight from Syracuse to Missouri?

Currently, June is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $179). Flying from Syracuse to Missouri in February is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 12, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,186 reviews

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,186 reviews
Delta
7.9
Good
8,186 reviews

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,283 reviews
Delta
7.9
Good
8,186 reviews

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,275 reviews
Delta
7.9
Good
8,186 reviews

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Missouri?

    If you book a flight to Missouri from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • How long is the flight from Syracuse to Missouri?

    Airlines like American Airlines, United Airlines, and Delta fly from Syracuse to Missouri in about 4h 42m. The time it takes to get you to your destination can typically vary by up to 48m. The distance between Syracuse and Missouri is about 801 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Syracuse to Missouri one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $118. Users have also found prices from $125 and $142 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Syracuse to Missouri?

    Most travelers choose Syracuse Hancock Intl - Lambert-St Louis, Syracuse Hancock Intl - Kansas City or Syracuse Hancock Intl - Springfield-Branson when deciding on the best route from Syracuse to Missouri.

  • Can I find deals for flights from Syracuse to Missouri that include hotel bookings?

    Yes. In addition to deals on Syracuse to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Missouri.

  • Can I find deals for business class flights from Syracuse to Missouri?

    Yes. Cheapflights offers flight deals from Syracuse to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Missouri?

    Currently, June is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $179). Flying from Syracuse to Missouri in February is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Syracuse to Missouri

Discover the top 3 airlines that operate flights from Syracuse to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$386FlexibilityNo cancel feeOn-time71%
DeltaCheapest$247Average$336FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$423FlexibilityNo cancel feeOn-time69%

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