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$150+ Cheap flights from Syracuse (SYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — STL
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Syracuse to Missouri

Keep the following information in mind while searching for Syracuse to Missouri flight deals. Data was last updated August 18, 2025.

Round-trip from

$223
(FlightHub)

One-way from

$150
(FlightHub)

Popular in

May

Cheapest in

February

Average price

$339
From Syracuse Hancock Intl to Missouri
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One-way flight from Syracuse Hancock Intl to Missouri
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Syracuse to Missouri

Cheapest flights from Syracuse to Missouri
Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:40 pmSYR - STL
1 stop18h 37mFrontier
Sun 11/211:17 amSTL - SYR
1 stop22h 51mFrontier
Deal found 8/18$223
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:47 pmSYR - STL
1 stop5h 20mAmerican Airlines
Sun 9/286:05 amSTL - SYR
1 stop4h 03mAmerican Airlines
Deal found 8/17$249
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:56 pmSYR - STL
1 stop5h 00mAmerican Airlines
Tue 11/116:00 amSTL - SYR
2 stops7h 10mAmerican Airlines
Deal found 8/17$254
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:00 pmSYR - MCI
1 stop6h 52mDelta
Tue 10/215:43 pmMCI - SYR
1 stop4h 41mDelta
Deal found 8/16$259
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/11:00 pmSYR - MCI
2 stops8h 47mAmerican Airlines
Wed 10/86:00 amMCI - SYR
1 stop4h 20mAmerican Airlines
Deal found 8/17$264
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/305:33 amSYR - SGF
2 stops10h 36mDelta
Sat 9/63:54 pmSGF - SYR
1 stop6h 57mDelta
Deal found 8/16$269
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/65:55 amSYR - SGF
1 stop6h 01mDelta
Wed 9/105:59 pmSGF - SYR
1 stop4h 52mDelta
Deal found 8/17$270
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:40 pmSYR - STL
1 stop18h 37mFrontier
Sun 11/911:17 amSTL - SYR
1 stop22h 51mFrontier
Deal found 8/17$271
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/34:48 pmSYR - MCI
1 stop4h 59mAmerican Airlines
Sat 9/66:00 amMCI - SYR
1 stop5h 28mAmerican Airlines
Deal found 8/16$274
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:00 amSYR - STL
1 stop5h 26mDelta
Wed 10/156:40 amSTL - SYR
1 stop4h 13mDelta
Deal found 8/16$274
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/219:37 pmSYR - STL
1 stop17h 44mFrontier
Sun 8/242:02 pmSTL - SYR
1 stop18h 26mFrontier
Deal found 8/17$275
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:39 pmSYR - MCI
1 stop6h 13mDelta
Sat 10/185:39 pmMCI - SYR
1 stop5h 41mDelta
Deal found 8/16$279

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Syracuse to Missouri that are best for you.

Fly from

Syracuse

Fly to

Missouri

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 10/30

7:40 pm-1:17 pm

1 stop18h 37m

Lambert-St Louis

Sun 11/2

11:17 am-11:08 am

1 stop22h 51m

$223

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 10/2

6:10 am-12:23 pm

1 stop7h 13m

Lambert-St Louis

Sun 10/5

5:27 am-11:00 am

1 stop4h 33m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 9/27

5:55 am-12:21 pm

1 stop7h 26m

Lambert-St Louis

Sat 10/4

6:40 am-11:54 am

1 stop4h 14m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 9/26

5:52 pm-9:10 pm

1 stop4h 18m

Lambert-St Louis

Sun 9/28

5:27 am-11:00 am

1 stop4h 33m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 12/30

7:11 pm-11:39 pm

1 stop5h 28m

Lambert-St Louis

Sun 1/4

5:55 pm-11:10 pm

1 stop4h 15m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 11/8

5:40 pm-8:33 pm

1 stop3h 53m

Lambert-St Louis

Tue 11/11

6:45 am-11:55 am

1 stop4h 10m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 9/11

5:28 pm-11:53 pm

1 stop7h 25m

Lambert-St Louis

Mon 9/15

3:56 pm-9:46 pm

1 stop4h 50m

$249

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 10/15

6:14 am-11:32 am

1 stop6h 18m

Kansas City

Sat 10/18

5:51 pm-11:04 pm

1 stop4h 13m

$259

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 10/1

5:52 pm-10:10 pm

1 stop5h 18m

Kansas City

Wed 10/8

6:02 am-12:04 pm

1 stop5h 02m

$259

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Tue 10/14

6:00 am-12:29 pm

1 stop7h 29m

Kansas City

Sat 10/18

6:15 am-11:53 am

1 stop4h 38m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 43 results
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Best time to book a flight from Syracuse to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Missouri

What is the cheapest month to book a flight from Syracuse to Missouri?

Currently, August is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $311). Flying from Syracuse to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to MO?

Find hourly flight availability from Syracuse to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Syracuse to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 18, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,925 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Missouri?

    If you book a flight to Missouri from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • How long is the flight from Syracuse to Missouri?

    Airlines like Frontier, American Airlines, and Delta fly from Syracuse to Missouri in about 7h 13m. The time it takes to get you to your destination can typically vary by up to 11h 24m. The distance between Syracuse and Missouri is about 801 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Syracuse to Missouri one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $150. Users have also found prices from $232 and $271 on American Airlines and Delta, respectively.

  • What are the most popular routes from Syracuse to Missouri?

    Most travelers choose Syracuse Hancock Intl - Lambert-St Louis, Syracuse Hancock Intl - Kansas City or Syracuse Hancock Intl - Springfield-Branson when deciding on the best route from Syracuse to Missouri.

  • Can I find deals for flights from Syracuse to Missouri that include hotel bookings?

    Yes. In addition to deals on Syracuse to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Missouri.

  • Can I find deals for business class flights from Syracuse to Missouri?

    Yes. Cheapflights offers flight deals from Syracuse to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $311). Flying from Syracuse to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Syracuse to Missouri

Discover the top 3 airlines that operate flights from Syracuse to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$442FlexibilityNo cancel feeOn-time71%
DeltaCheapest$247Average$347FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$286Average$511FlexibilityNo cancel feeOn-time69%

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