Missouri

$127+ Cheap flights from Syracuse (SYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — STL
Jan 28 — Feb 41
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Cheap flight deals from Syracuse to Missouri

Cheapest flights from Syracuse to Missouri
Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.

This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amSYR - STL
1 stop7h 20mDelta
Wed 1/76:35 amSTL - SYR
1 stop4h 26mDelta
Deal found 12/26$295
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amSYR - STL
1 stop4h 24mDelta
Sun 1/45:59 pmSTL - SYR
1 stop5h 00mDelta
Deal found 12/28$354
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:07 pmSYR - STL
1 stop5h 35mDelta
Wed 1/76:35 amSTL - SYR
1 stop4h 26mDelta
Deal found 12/26$539
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:00 amSYR - STL
2 stops12h 43mUnited Airlines
Wed 1/78:30 amSTL - SYR
1 stop4h 37mUnited Airlines
Deal found 12/26$639
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:45 amSYR - STL
1 stop5h 23mUnited Airlines
Sun 1/45:02 pmSTL - SYR
3 stops29h 19mUnited Airlines
Deal found 12/27$755
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:29 pmSYR - STL
2 stops7h 26mAmerican Airlines
Sun 1/46:35 pmSTL - SYR
1 stop5h 07mAmerican Airlines
Deal found 12/27$765
This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:12 pmSYR - STL
2 stops15h 44mMultiple Airlines
Mon 12/2910:40 amSTL - SYR
1 stop7h 37mMultiple Airlines
Deal found 12/27$843
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:25 amSYR - STL
1 stop13h 06mAmerican Airlines
Wed 1/79:54 amSTL - SYR
1 stop5h 45mAmerican Airlines
Deal found 12/26$857

Find flight deals from Syracuse to Missouri

Keep the following information in mind while searching for Syracuse to Missouri flight deals. Data was last updated December 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$251
(American Airlines)

One-way from

$127
(Kiwi.com)

Popular in

March

Cheapest in

January

Average price

$420
Provider with most accurate pricing for Syracuse Hancock Intl-Lambert-St Louis flight deals.
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Lambert-St Louis flights.
From Syracuse Hancock Intl to Missouri
One-way flight from Syracuse Hancock Intl to Missouri
High demand for flights, 0% potential price rise
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 29, 2025.
Use the filters below to find and compare flights from Syracuse to Missouri that are best for you.

Fly from

Syracuse

Fly to

Missouri

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 3/4

11:34 am-6:11 pm

1 stop7h 37m

Lambert-St Louis

Sat 3/7

6:00 am-11:59 am

1 stop4h 59m

$251

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 5/16

6:50 pm-11:38 pm

1 stop5h 48m

Lambert-St Louis

Tue 5/19

5:45 pm-10:56 pm

1 stop4h 11m

$251

SyracuseSpringfield

SYR - SGF

SYRSGF

Syracuse Hancock Intl

Wed 1/21

2:42 pm-9:58 pm

2 stops8h 16m

Springfield-Branson

Wed 1/28

7:45 am-4:15 pm

1 stop7h 30m

$256

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 3/7

3:00 pm-7:39 pm

1 stop5h 39m

Lambert-St Louis

Mon 3/9

5:59 pm-11:09 pm

1 stop4h 10m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/28

5:50 am-9:32 am

1 stop4h 42m

Lambert-St Louis

Mon 3/2

5:50 pm-11:13 pm

1 stop4h 23m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/7

6:15 am-12:36 pm

1 stop7h 21m

Lambert-St Louis

Sun 2/8

5:56 pm-11:13 pm

1 stop4h 17m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 1/22

4:57 pm-10:58 pm

1 stop7h 01m

Lambert-St Louis

Sat 1/24

7:00 am-1:10 pm

1 stop5h 10m

$269

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 1/23

4:32 pm-8:43 pm

1 stop5h 11m

Lambert-St Louis

Sun 1/25

5:56 pm-11:13 pm

1 stop4h 17m

$269

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/7

12:06 pm-5:01 pm

1 stop5h 55m

Lambert-St Louis

Sun 2/8

6:00 am-2:38 pm

2 stops7h 38m

$276

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Thu 3/12

5:30 am-12:19 pm

1 stop7h 49m

Kansas City

Tue 3/24

9:17 am-4:15 pm

1 stop5h 58m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 38 results
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Best time to book a flight from Syracuse to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Missouri

What is the cheapest month to book a flight from Syracuse to Missouri?

Currently, June is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $179). Flying from Syracuse to Missouri in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 29, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Syracuse to Missouri?

    If you book a flight to Missouri from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • How long is the flight from Syracuse to Missouri?

    Airlines like American Airlines, Delta, and United Airlines fly from Syracuse to Missouri in about 5h 48m. The time it takes to get you to your destination can typically vary by up to 1h 49m. The distance between Syracuse and Missouri is about 801 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Syracuse to Missouri one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $118. Users have also found prices from $125 and $142 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Syracuse to Missouri?

  • Can I find deals for flights from Syracuse to Missouri that include hotel bookings?

    Yes. In addition to deals on Syracuse to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Missouri.

  • Can I find deals for business class flights from Syracuse to Missouri?

    Yes. Cheapflights offers flight deals from Syracuse to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Missouri?

    Currently, June is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $179). Flying from Syracuse to Missouri in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Syracuse to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Syracuse to Missouri

Discover the top 3 airlines that operate flights from Syracuse to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$392FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$423FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$335FlexibilityNo cancel feeOn-timeN/A

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