How long is the flight from Syracuse to Missouri?

Airlines like American Airlines, Delta, and United Airlines fly from Syracuse to Missouri in about 5h 48m. The time it takes to get you to your destination can typically vary by up to 1h 49m. The distance between Syracuse and Missouri is about 801 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Syracuse to Missouri one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $118. Users have also found prices from $125 and $142 on American Airlines and United Airlines, respectively.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular routes from Syracuse to Missouri?

Most travelers choose Syracuse Hancock Intl - Lambert-St Louis, Syracuse Hancock Intl - Springfield-Branson or Syracuse Hancock Intl - Kansas City when deciding on the best route from Syracuse to Missouri.

What are the most popular airlines that fly from Syracuse to Missouri?

When booking a flight from Syracuse to Missouri, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest time of day to fly from SYR to MO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Syracuse to Missouri as you normally would.

What airport do you fly from for flights from Syracuse to Missouri?

If you book a flight to Missouri from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

Can I find deals for flights from Syracuse to Missouri that include hotel bookings?

Yes. In addition to deals on Syracuse to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Syracuse to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Missouri.

Can I find deals for business class flights from Syracuse to Missouri?

Yes. Cheapflights offers flight deals from Syracuse to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$127+ Flights from Syracuse to Missouri

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Cheap flight deals from Syracuse to Missouri

Cheapest flights from Syracuse to Missouri
Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.

Wed 12/317:00 amSYR - STL

1 stop7h 20mDelta

Wed 1/76:35 amSTL - SYR

1 stop4h 26mDelta

Deal found 12/26

$295

Tue 12/306:00 amSYR - STL

1 stop4h 24mDelta

Sun 1/45:59 pmSTL - SYR

1 stop5h 00mDelta

Deal found 12/28

$354

Sat 12/277:07 pmSYR - STL

1 stop5h 35mDelta

Wed 1/76:35 amSTL - SYR

1 stop4h 26mDelta

Deal found 12/26

$539

Wed 12/3111:00 amSYR - STL

2 stops12h 43mUnited Airlines

Wed 1/78:30 amSTL - SYR

1 stop4h 37mUnited Airlines

Deal found 12/26

$639

Tue 12/305:45 amSYR - STL

1 stop5h 23mUnited Airlines

Sun 1/45:02 pmSTL - SYR

3 stops29h 19mUnited Airlines

Deal found 12/27

$755

Tue 12/305:29 pmSYR - STL

2 stops7h 26mAmerican Airlines

Sun 1/46:35 pmSTL - SYR

1 stop5h 07mAmerican Airlines

Deal found 12/27

$765

Sat 12/278:12 pmSYR - STL

2 stops15h 44mMultiple Airlines

Mon 12/2910:40 amSTL - SYR

1 stop7h 37mMultiple Airlines

Deal found 12/27

$843

Sat 12/277:25 amSYR - STL

1 stop13h 06mAmerican Airlines

Wed 1/79:54 amSTL - SYR

1 stop5h 45mAmerican Airlines

Deal found 12/26

$857

Best flights from Syracuse to Missouri
Discover carefully curated flight deals from Syracuse to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 29, 2025.

Wed 3/411:34 amSYR - STL

1 stop7h 37mAmerican Airlines

Sat 3/76:00 amSTL - SYR

1 stop4h 59mAmerican Airlines

Deal found 12/27

$251

Sat 5/166:50 pmSYR - STL

1 stop5h 48mDelta

Tue 5/195:45 pmSTL - SYR

1 stop4h 11mDelta

Deal found 12/28

$251

Wed 1/212:42 pmSYR - SGF

2 stops8h 16mUnited Airlines

Wed 1/287:45 amSGF - SYR

1 stop7h 30mUnited Airlines

Deal found 12/29

$256

Sat 3/73:00 pmSYR - STL

1 stop5h 39mDelta

Mon 3/95:59 pmSTL - SYR

1 stop4h 10mDelta

Deal found 12/27

$260

Thu 1/224:57 pmSYR - STL

1 stop7h 01mUnited Airlines

Sat 1/247:00 amSTL - SYR

1 stop5h 10mUnited Airlines

Deal found 12/27

$269

Sat 2/712:06 pmSYR - STL

1 stop5h 55mAmerican Airlines

Sun 2/86:00 amSTL - SYR

2 stops7h 38mAmerican Airlines

Deal found 12/26

$276

Sat 2/285:50 amSYR - STL

1 stop4h 42mDelta

Mon 3/25:50 pmSTL - SYR

1 stop4h 23mDelta

Deal found 12/27

$260

Thu 3/125:30 amSYR - MCI

1 stop7h 49mAmerican Airlines

Tue 3/249:17 amMCI - SYR

1 stop5h 58mAmerican Airlines

Deal found 12/28

$279

Sat 2/76:15 amSYR - STL

1 stop7h 21mDelta

Sun 2/85:56 pmSTL - SYR

1 stop4h 17mDelta

Deal found 12/26

$260

Thu 1/292:15 pmSYR - MCI

2 stops9h 24mAmerican Airlines

Sun 2/16:06 amMCI - SYR

1 stop6h 44mAmerican Airlines

Deal found 12/26

$284

Tue 1/204:57 pmSYR - SGF

1 stop6h 01mUnited Airlines

Sat 1/241:26 pmSGF - SYR

1 stop8h 47mUnited Airlines

Deal found 12/26

$321

Fri 1/234:32 pmSYR - STL

1 stop5h 11mDelta

Sun 1/255:56 pmSTL - SYR

1 stop4h 17mDelta

Deal found 12/28

$269

Sat 3/216:00 amSYR - STL

1 stop7h 28mAmerican Airlines

Mon 3/236:00 amSTL - SYR

1 stop4h 15mAmerican Airlines

Deal found 12/27

$291

Tue 1/208:00 amSYR - COU

1 stop7h 35mUnited Airlines

Sat 1/248:09 amCOU - SYR

1 stop7h 06mUnited Airlines

Deal found 12/26

$328

Sat 1/176:15 amSYR - MCI

1 stop6h 18mDelta

Tue 1/205:47 pmMCI - SYR

1 stop4h 26mDelta

Deal found 12/27

$279

Tue 3/176:17 amSYR - SGF

1 stop6h 18mAmerican Airlines

Sat 3/216:00 pmSGF - SYR

1 stop4h 44mAmerican Airlines

Deal found 12/28

$294

Thu 1/295:50 amSYR - MCI

1 stop5h 05mDelta

Sun 2/15:47 pmMCI - SYR

1 stop4h 26mDelta

Deal found 12/26

$279

Mon 1/194:57 pmSYR - COU

1 stop5h 40mUnited Airlines

Mon 2/163:10 pmCOU - SYR

1 stop4h 42mUnited Airlines

Deal found 12/27

$363

Sat 2/285:50 amSYR - MCI

1 stop6h 43mDelta

Sat 3/75:47 pmMCI - SYR

1 stop4h 26mDelta

Deal found 12/28

$279

Thu 3/126:00 amSYR - MCI

1 stop5h 56mDelta

Tue 3/246:00 amMCI - SYR

1 stop5h 00mDelta

Deal found 12/27

$279

Fri 2/66:00 amSYR - SGF

1 stop6h 20mDelta

Mon 2/95:00 pmSGF - SYR

1 stop5h 51mDelta

Deal found 12/27

$279

Mon 1/197:00 amSYR - COU

1 stop8h 48mAmerican Airlines

Mon 2/1610:07 amCOU - SYR

2 stops13h 21mAmerican Airlines

Deal found 12/27

$402

Wed 3/46:37 pmSYR - STL

1 stop5h 59mDelta

Sat 3/75:50 pmSTL - SYR

1 stop4h 23mDelta

Deal found 12/28

$305

Wed 2/185:50 pmSYR - MCI

1 stop6h 25mDelta

Sun 2/225:47 pmMCI - SYR

1 stop4h 26mDelta

Deal found 12/26

$319

Fri 6/266:50 pmSYR - STL

1 stop5h 48mDelta

Sun 6/285:30 pmSTL - SYR

1 stop5h 29mDelta

Deal found 12/27

$324

Last-minute flights from Syracuse to Missouri
Discover last-minute flight deals from Syracuse to Missouri. Data last updated December 29, 2025 and is based on user searches.

Wed 12/317:00 amSYR - STL

1 stop7h 20mDelta

Wed 1/76:35 amSTL - SYR

1 stop4h 26mDelta

Deal found 12/26

$295

Mon 1/57:26 pmSYR - STL

1 stop5h 18mAmerican Airlines

Wed 1/146:00 amSTL - SYR

1 stop5h 00mAmerican Airlines

Deal found 12/27

$309

Sat 1/176:15 amSYR - MCI

1 stop6h 18mDelta

Tue 1/205:47 pmMCI - SYR

1 stop4h 26mDelta

Deal found 12/27

$279

Sat 1/178:00 amSYR - STL

1 stop7h 28mUnited Airlines

Wed 1/219:57 amSTL - SYR

1 stop5h 18mUnited Airlines

Deal found 12/27

$330

Sat 1/1712:06 pmSYR - MCI

2 stops12h 06mAmerican Airlines

Tue 1/206:23 amMCI - SYR

1 stop6h 52mAmerican Airlines

Deal found 12/27

$344

Tue 1/204:57 pmSYR - SGF

1 stop6h 01mUnited Airlines

Sat 1/241:26 pmSGF - SYR

1 stop8h 47mUnited Airlines

Deal found 12/28

$321

Tue 1/208:00 amSYR - COU

1 stop7h 35mUnited Airlines

Sat 1/248:09 amCOU - SYR

1 stop7h 06mUnited Airlines

Deal found 12/28

$328

Wed 1/217:08 amSYR - SGF

1 stop6h 07mAmerican Airlines

Wed 1/285:00 pmSGF - SYR

1 stop5h 54mAmerican Airlines

Deal found 12/29

$251

Wed 1/212:42 pmSYR - SGF

2 stops8h 16mUnited Airlines

Wed 1/289:05 amSGF - SYR

2 stops11h 15mUnited Airlines

Deal found 12/29

$261

Thu 1/224:57 pmSYR - STL

1 stop7h 01mUnited Airlines

Sat 1/247:00 amSTL - SYR

1 stop5h 10mUnited Airlines

Deal found 12/27

$269

Fri 1/232:15 pmSYR - STL

2 stops7h 17mAmerican Airlines

Sun 1/256:00 amSTL - SYR

2 stops7h 38mAmerican Airlines

Deal found 12/28

$279

Thu 1/292:15 pmSYR - MCI

2 stops9h 24mAmerican Airlines

Sun 2/16:06 amMCI - SYR

1 stop6h 44mAmerican Airlines

Deal found 12/26

$284

One-way flights from Syracuse to Missouri
Search for one-way flight options from Syracuse to Missouri. Find affordable one-way fares based on user searches. Data last updated December 29, 2025.

Mon 1/1911:17 amSYR - MCI

1 stop29h 52mMultiple Airlines

Deal found 12/29

$127

Mon 2/28:55 pmSYR - STL

2 stops27h 38mMultiple Airlines

Deal found 12/27

$134

Tue 2/312:31 pmSYR - STL

2 stops36h 02mMultiple Airlines

Deal found 12/27

$135

Thu 4/166:03 pmSYR - MCI

1 stop18h 04mMultiple Airlines

Deal found 12/27

$144

Sun 2/86:41 pmSYR - STL

2 stops29h 52mMultiple Airlines

Deal found 12/27

$154

Mon 1/2612:02 pmSYR - MCI

2 stops29h 07mMultiple Airlines

Deal found 12/29

$156

Thu 2/58:04 pmSYR - STL

2 stops43h 42mMultiple Airlines

Deal found 12/27

$158

Mon 1/123:20 pmSYR - MCI

1 stop25h 49mMultiple Airlines

Deal found 12/29

$179

Mon 1/58:12 pmSYR - STL

2 stops15h 44mMultiple Airlines

Deal found 12/27

$182

Mon 1/58:12 pmSYR - STL

1 stop27h 21mFrontier

Deal found 12/27

$216

Fri 2/612:02 pmSYR - STL

3 stops19h 49mMultiple Airlines

Deal found 12/27

$218

Thu 2/57:05 amSYR - STL

1 stop15h 10mAmerican Airlines

Deal found 12/27

$229

Find flight deals from Syracuse to Missouri

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$251 (American Airlines)
One-way from	$127 (Kiwi.com)
Popular in	March
Cheapest in	January
Average price	$420

Provider with most accurate pricing for Syracuse Hancock Intl-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Lambert-St Louis flights.

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From Syracuse Hancock Intl to Missouri

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One-way flight from Syracuse Hancock Intl to Missouri

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High demand for flights, 0% potential price rise

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 3/4

11:34 am-6:11 pm

1 stop7h 37m

Lambert-St Louis

Sat 3/7

6:00 am-11:59 am

1 stop4h 59m

$251

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 5/16

6:50 pm-11:38 pm

1 stop5h 48m

Lambert-St Louis

Tue 5/19

5:45 pm-10:56 pm

1 stop4h 11m

$251

SyracuseSpringfield

SYR - SGF

SYRSGF

Syracuse Hancock Intl

Wed 1/21

2:42 pm-9:58 pm

2 stops8h 16m

Springfield-Branson

Wed 1/28

7:45 am-4:15 pm

1 stop7h 30m

$256

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 3/7

3:00 pm-7:39 pm

1 stop5h 39m

Lambert-St Louis

Mon 3/9

5:59 pm-11:09 pm

1 stop4h 10m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/28

5:50 am-9:32 am

1 stop4h 42m

Lambert-St Louis

Mon 3/2

5:50 pm-11:13 pm

1 stop4h 23m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/7

6:15 am-12:36 pm

1 stop7h 21m

Lambert-St Louis

Sun 2/8

5:56 pm-11:13 pm

1 stop4h 17m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 1/22

4:57 pm-10:58 pm

1 stop7h 01m

Lambert-St Louis

Sat 1/24

7:00 am-1:10 pm

1 stop5h 10m

$269

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 1/23

4:32 pm-8:43 pm

1 stop5h 11m

Lambert-St Louis

Sun 1/25

5:56 pm-11:13 pm

1 stop4h 17m

$269

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/7

12:06 pm-5:01 pm

1 stop5h 55m

Lambert-St Louis

Sun 2/8

6:00 am-2:38 pm

2 stops7h 38m

$276

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Thu 3/12

5:30 am-12:19 pm

1 stop7h 49m

Kansas City

Tue 3/24

9:17 am-4:15 pm

1 stop5h 58m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 38 results

Best time to book a flight from Syracuse to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Syracuse with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Missouri

What is the cheapest month to book a flight from Syracuse to Missouri?

Currently, June is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $179). Flying from Syracuse to Missouri in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,014 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Delta

7.9

Good

8,014 reviews

Delta

7.9

Good

8,014 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

United Airlines

7.4

Good

9,118 reviews

Delta

7.9

Good

8,014 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

American Airlines

7.2

Good

11,072 reviews

Delta

7.9

Good

8,014 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Related info for your journey

What airport do you fly from for flights from Syracuse to Missouri?
If you book a flight to Missouri from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.
How long is the flight from Syracuse to Missouri?
Airlines like American Airlines, Delta, and United Airlines fly from Syracuse to Missouri in about 5h 48m. The time it takes to get you to your destination can typically vary by up to 1h 49m. The distance between Syracuse and Missouri is about 801 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Syracuse to Missouri one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $118. Users have also found prices from $125 and $142 on American Airlines and United Airlines, respectively.
What are the most popular routes from Syracuse to Missouri?
Most travelers choose Syracuse Hancock Intl - Lambert-St Louis, Syracuse Hancock Intl - Springfield-Branson or Syracuse Hancock Intl - Kansas City when deciding on the best route from Syracuse to Missouri.
Can I find deals for flights from Syracuse to Missouri that include hotel bookings?
Yes. In addition to deals on Syracuse to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Syracuse to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Missouri.
Can I find deals for business class flights from Syracuse to Missouri?
Yes. Cheapflights offers flight deals from Syracuse to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Syracuse to Missouri?
Currently, June is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $179). Flying from Syracuse to Missouri in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Missouri car rentals

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Kansas City Airport car rentals

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Top 3 airlines flying from Syracuse to Missouri

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$198	Average$392	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$248	Average$423	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$248	Average$335	FlexibilityNo cancel fee	On-timeN/A

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$127+ Cheap flights from Syracuse (SYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Syracuse to Missouri

Cheapest flights from Syracuse to MissouriExplore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.

Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.

Find flight deals from Syracuse to Missouri

Keep the following information in mind while searching for Syracuse to Missouri flight deals. Data was last updated December 29, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Syracuse to Missouri that are best for you.

Best time to book a flight from Syracuse to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Syracuse with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Missouri

What is the cheapest month to book a flight from Syracuse to Missouri?

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Syracuse to Missouri?

How long is the flight from Syracuse to Missouri?

What are the cheapest airlines to fly from Syracuse to Missouri one-way?

What are the most popular routes from Syracuse to Missouri?

Can I find deals for flights from Syracuse to Missouri that include hotel bookings?

How can I find direct flights from Syracuse to Missouri?

Can I find deals for business class flights from Syracuse to Missouri?

What is the cheapest month to book a flight from Syracuse to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Syracuse to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Syracuse to Missouri

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Cheapest flights from Syracuse to Missouri
Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.