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Missouri

$94+ Cheap flights from Syracuse (SYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — STL
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Syracuse to Missouri

Keep the following information in mind while searching for Syracuse to Missouri flight deals. Data was last updated September 17, 2025.

Round-trip from

$182
(Frontier)

One-way from

$94
(Booking.com)

Popular in

May

Cheapest in

February

Average price

$403
From Syracuse Hancock Intl to Missouri
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One-way flight from Syracuse Hancock Intl to Missouri
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Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Syracuse to Missouri

Cheapest flights from Syracuse to Missouri
Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1111:59 amSYR - STL
1 stop25h 47mFrontier
Fri 10/176:05 pmSTL - SYR
1 stop19h 11mFrontier
Deal found 9/17$182
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:59 pmSYR - STL
1 stop22h 11mFrontier
Sat 10/184:33 pmSTL - SYR
1 stop24h 54mFrontier
Deal found 9/17$208
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:59 pmSYR - STL
1 stop5h 40mDelta
Sun 1/45:55 pmSTL - SYR
1 stop4h 20mDelta
Deal found 9/15$249
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:15 amSYR - STL
1 stop5h 34mUnited Airlines
Sat 10/186:30 amSTL - SYR
2 stops6h 44mUnited Airlines
Deal found 9/17$254
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:00 amSYR - MCI
1 stop7h 29mDelta
Mon 11/105:47 pmMCI - SYR
1 stop4h 23mDelta
Deal found 9/17$259
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:55 amSYR - STL
1 stop5h 04mDelta
Sat 10/45:27 pmSTL - SYR
1 stop4h 27mDelta
Deal found 9/14$259
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:42 amSYR - MCI
1 stop5h 13mAmerican Airlines
Sat 10/256:02 amMCI - SYR
2 stops7h 23mAmerican Airlines
Deal found 9/14$264
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/912:16 pmSYR - STL
1 stop23h 21mFrontier
Sat 10/114:33 pmSTL - SYR
1 stop26h 37mFrontier
Deal found 9/17$270
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:30 amSYR - STL
1 stop4h 50mAmerican Airlines
Sun 11/97:00 amSTL - SYR
1 stop4h 52mAmerican Airlines
Deal found 9/15$274
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:35 pmSYR - MCI
1 stop21h 41mMultiple Airlines
Thu 10/305:15 amMCI - SYR
1 stop12h 44mMultiple Airlines
Deal found 9/16$275
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:15 amSYR - STL
1 stop5h 34mUnited Airlines
Sat 10/1112:25 pmSTL - SYR
2 stops9h 53mUnited Airlines
Deal found 9/17$280
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:52 pmSYR - STL
1 stop4h 18mAmerican Airlines
Fri 10/32:11 pmSTL - SYR
1 stop6h 51mAmerican Airlines
Deal found 9/16$284

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Syracuse to Missouri that are best for you.

Fly from

Syracuse

Fly to

Missouri

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 10/11

11:59 am-12:46 pm

1 stop25h 47m

Lambert-St Louis

Fri 10/17

6:05 pm-2:16 pm

1 stop19h 11m

$182

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 10/25

11:20 am-4:43 pm

1 stop6h 23m

Lambert-St Louis

Wed 10/29

5:40 pm-11:06 pm

1 stop4h 26m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 10/14

8:13 pm-11:54 pm

1 stop4h 41m

Lambert-St Louis

Tue 10/21

10:54 am-4:56 pm

1 stop5h 02m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 12/30

6:59 pm-11:39 pm

1 stop5h 40m

Lambert-St Louis

Sun 1/4

5:55 pm-11:15 pm

1 stop4h 20m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 10/28

2:53 pm-6:46 pm

1 stop4h 53m

Lambert-St Louis

Sat 11/1

7:23 am-12:53 pm

1 stop4h 30m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 10/29

6:00 am-12:35 pm

1 stop7h 35m

Lambert-St Louis

Sat 11/1

6:40 am-11:53 am

1 stop4h 13m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 10/30

6:00 am-9:37 am

1 stop4h 37m

Lambert-St Louis

Sun 11/2

3:59 pm-12:20 am

1 stop7h 21m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 10/16

6:15 am-10:49 am

1 stop5h 34m

Lambert-St Louis

Sat 10/18

6:30 am-2:14 pm

2 stops6h 44m

$254

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 10/2

6:15 am-10:49 am

1 stop5h 34m

Lambert-St Louis

Sun 10/5

5:00 am-11:58 am

1 stop5h 58m

$259

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 11/5

3:57 pm-11:44 pm

1 stop8h 47m

Kansas City

Sat 11/8

11:48 am-5:17 pm

1 stop4h 29m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 46 results
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Best time to book a flight from Syracuse to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Missouri

What is the cheapest month to book a flight from Syracuse to Missouri?

Currently, August is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $311). Flying from Syracuse to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to MO?

Find hourly flight availability from Syracuse to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Syracuse to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 17, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Missouri?

    If you book a flight to Missouri from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • How long is the flight from Syracuse to Missouri?

    Airlines like Frontier, Delta, and American Airlines fly from Syracuse to Missouri in about 4h 41m. The time it takes to get you to your destination can typically vary by up to 21h 06m. The distance between Syracuse and Missouri is about 801 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Syracuse to Missouri one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $94. Users have also found prices from $249 and $271 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Syracuse to Missouri?

    Most travelers choose Syracuse Hancock Intl - Kansas City, Syracuse Hancock Intl - Lambert-St Louis or Syracuse Hancock Intl - Springfield-Branson when deciding on the best route from Syracuse to Missouri.

  • Can I find deals for flights from Syracuse to Missouri that include hotel bookings?

    Yes. In addition to deals on Syracuse to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Missouri.

  • Can I find deals for business class flights from Syracuse to Missouri?

    Yes. Cheapflights offers flight deals from Syracuse to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $311). Flying from Syracuse to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Syracuse to Missouri

Discover the top 3 airlines that operate flights from Syracuse to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$422FlexibilityNo cancel feeOn-time71%
DeltaCheapest$247Average$342FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$306Average$534FlexibilityNo cancel feeOn-time69%

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