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$115+ Cheap flights from Syracuse (SYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — STL
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Syracuse to Missouri

Keep the following information in mind while searching for Syracuse to Missouri flight deals. Data was last updated April 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(American Airlines)

One-way from

$115
(Frontier)

Popular in

March

Cheapest in

September

Average price

$328
Provider with most accurate pricing for Syracuse Hancock Intl-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Kansas City flights.
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From Syracuse Hancock Intl to Missouri
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One-way flight from Syracuse Hancock Intl to Missouri
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High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Syracuse to Missouri

Cheapest flights from Syracuse to Missouri
Explore the most affordable flight options available from Syracuse to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:29 pmSYR - MCI
1 stop7h 30mAmerican Airlines
Mon 6/25:45 pmMCI - SYR
1 stop5h 04mAmerican Airlines
Deal found 4/27$229
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/26:20 amSYR - MCI
1 stop5h 15mUnited Airlines
Tue 7/153:28 pmMCI - SYR
2 stops7h 31mUnited Airlines
Deal found 4/29$234
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:50 amSYR - MCI
1 stop7h 20mDelta
Mon 6/25:26 pmMCI - SYR
1 stop5h 33mDelta
Deal found 4/27$248
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:50 pmSYR - STL
1 stop5h 49mDelta
Mon 8/185:45 pmSTL - SYR
1 stop4h 11mDelta
Deal found 4/28$249
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/134:29 pmSYR - STL
1 stop5h 01mAmerican Airlines
Tue 6/176:00 amSTL - SYR
2 stops6h 22mAmerican Airlines
Deal found 4/28$254
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/216:00 amSYR - STL
2 stops9h 33mUnited Airlines
Mon 8/259:17 amSTL - SYR
1 stop6h 29mUnited Airlines
Deal found 4/28$324
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/64:29 pmSYR - SGF
1 stop6h 30mAmerican Airlines
Mon 6/94:22 pmSGF - SYR
1 stop5h 38mAmerican Airlines
Deal found 4/29$419
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/199:46 amSYR - MCI
1 stop10h 25mMultiple Airlines
Sun 6/227:50 pmMCI - SYR
2 stops13h 50mMultiple Airlines
Deal found 4/28$440
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/66:10 amSYR - SGF
2 stops9h 55mDelta
Mon 6/93:57 pmSGF - SYR
1 stop7h 00mDelta
Deal found 4/29$504
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/152:23 pmSYR - SGF
1 stop8h 38mUnited Airlines
Sun 5/1811:29 amSGF - SYR
1 stop8h 51mUnited Airlines
Deal found 4/29$701

Cheapflights Fare Finder

Customize your flight search to find flights from Syracuse to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Syracuse to Missouri that are best for you.

Fly from

Syracuse

Fly to

Missouri

Route

Depart

Return

Price

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 5/28

5:29 pm-11:59 pm

1 stop7h 30m

Kansas City

Mon 6/2

5:45 pm-11:49 pm

1 stop5h 04m

$229

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 7/2

6:20 am-10:35 am

1 stop5h 15m

Kansas City

Tue 7/15

3:28 pm-11:59 pm

2 stops7h 31m

$234

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Wed 5/28

5:50 am-12:10 pm

1 stop7h 20m

Kansas City

Mon 6/2

5:26 pm-11:59 pm

1 stop5h 33m

$248

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 6/13

6:00 am-9:43 am

1 stop4h 43m

Lambert-St Louis

Fri 6/20

3:42 pm-11:57 pm

1 stop7h 15m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 6/13

4:29 pm-8:30 pm

1 stop5h 01m

Lambert-St Louis

Tue 6/17

6:00 am-1:22 pm

2 stops6h 22m

$254

SyracuseSpringfield

SYR - SGF

SYRSGF

Syracuse Hancock Intl

Fri 6/6

4:29 pm-9:59 pm

1 stop6h 30m

Springfield-Branson

Mon 6/9

4:22 pm-11:00 pm

1 stop5h 38m

$419

SyracuseKansas City

SYR - MCI

SYRMCI

Syracuse Hancock Intl

Thu 6/19

9:46 am-7:11 pm

1 stop10h 25m

Kansas City

Sun 6/22

7:50 pm-10:40 am

2 stops13h 50m

$440

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 6/3

6:00 am-9:56 am

1 stop4h 56m

Lambert-St Louis

Wed 6/4

6:30 am-2:10 pm

2 stops6h 40m

$444

SyracuseSpringfield

SYR - SGF

SYRSGF

Syracuse Hancock Intl

Fri 6/6

6:10 am-3:05 pm

2 stops9h 55m

Springfield-Branson

Mon 6/9

3:57 pm-11:57 pm

1 stop7h 00m

$504

SyracuseSpringfield

SYR - SGF

SYRSGF

Syracuse Hancock Intl

Thu 5/15

2:23 pm-10:01 pm

1 stop8h 38m

Springfield-Branson

Sun 5/18

11:29 am-9:20 pm

1 stop8h 51m

$701

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 17 results
1
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Best time to book a flight from Syracuse to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Missouri

What is the cheapest month to book a flight from Syracuse to Missouri?

Currently, August is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $311). Flying from Syracuse to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to MO?

Find hourly flight availability from Syracuse to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Syracuse to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 30, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and American Airlines from Syracuse to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Frontier
6.0
Okay
3,284 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Missouri?

    If you book a flight to Missouri from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • What are the cheapest airlines to fly from Syracuse to Missouri one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $115. Users have also found prices from $150 and $190 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Syracuse to Missouri?

    Most travelers choose Syracuse Hancock Intl - Lambert-St Louis, Syracuse Hancock Intl - Kansas City or Syracuse Hancock Intl - Springfield-Branson when deciding on the best route from Syracuse to Missouri.

  • Can I find deals for flights from Syracuse to Missouri that include hotel bookings?

    Yes. In addition to deals on Syracuse to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Missouri.

  • Can I find deals for business class flights from Syracuse to Missouri?

    Yes. Cheapflights offers flight deals from Syracuse to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Syracuse to Missouri (average of $311). Flying from Syracuse to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Syracuse to Missouri

Discover the top 3 airlines that operate flights from Syracuse to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$182Average$461FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$208Average$482FlexibilityNo cancel feeOn-time69%
DeltaCheapest$246Average$382FlexibilityNo cancel feeOn-timeN/A

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