$152+ Cheap flights from Missouri to Syracuse (SYR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/24. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SYR
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Syracuse with Cheapflights
1. Tell us where you want to go
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Cheapest flights from Missouri to SyracuseExplore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- SYR
2 stops47h 03m
Multiple Airlines
Mon 6/110:21 am
SYR
- STL
1 stop14h 36m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:04 pm
STL
- SYR
1 stop3h 54m
Delta
Tue 8/46:54 pm
SYR
- STL
1 stop5h 59m
Delta
Deal found 4/28![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:01 pm
SGF
- SYR
1 stop5h 53m
American Airlines
Tue 9/16:02 am
SYR
- SGF
1 stop5h 01m
American Airlines
Deal found 4/29![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 pm
STL
- SYR
1 stop5h 07m
American Airlines
Thu 6/48:32 pm
SYR
- STL
1 stop4h 44m
American Airlines
Deal found 4/30![American Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:10 pm
STL
- SYR
1 stop3h 47m
Delta
Sun 6/216:11 am
SYR
- STL
1 stop4h 21m
Delta
Deal found 4/29![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
STL
- SYR
1 stop4h 53m
Delta
Wed 6/36:05 am
SYR
- STL
1 stop7h 18m
Delta
Deal found 4/27![Delta logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:19 pm
STL
- SYR
1 stop16h 12m
Multiple Airlines
Thu 6/47:26 pm
SYR
- STL
2 stops38h 29m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:27 pm
STL
- SYR
2 stops43h 17m
Multiple Airlines
Mon 6/110:21 am
SYR
- STL
1 stop14h 36m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:19 pm
STL
- SYR
1 stop16h 12m
Multiple Airlines
Mon 6/110:21 am
SYR
- STL
2 stops32h 12m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$337
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:04 pm
STL
- SYR
1 stop4h 45m
Delta
Sun 5/176:00 am
SYR
- STL
1 stop4h 44m
Delta
Deal found 4/27![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:00 am
MCI
- SYR
1 stop6h 16m
Delta
Sat 9/54:30 pm
SYR
- MCI
1 stop5h 31m
Delta
Deal found 4/28![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
STL
- SYR
2 stops7h 15m
United Airlines
Tue 6/96:15 am
SYR
- STL
1 stop6h 56m
United Airlines
Deal found 4/30![United Airlines logo]()
$341
Best flights from Missouri to SyracuseDiscover carefully curated flight deals from Missouri to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Missouri to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:49 am
STL
- SYR
1 stop7h 05m
Delta
Tue 6/96:00 am
SYR
- STL
1 stop6h 49m
Delta
Deal found 4/30![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:01 pm
SGF
- SYR
1 stop5h 53m
American Airlines
Tue 9/16:02 am
SYR
- SGF
1 stop5h 01m
American Airlines
Deal found 4/29![American Airlines logo]()
$300
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:13 pm
STL
- SYR
1 stop7h 06m
United Airlines
Mon 6/85:44 pm
SYR
- STL
1 stop4h 32m
United Airlines
Deal found 4/29![United Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:19 pm
STL
- SYR
1 stop16h 12m
Multiple Airlines
Mon 6/110:21 am
SYR
- STL
1 stop14h 36m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:26 pm
SGF
- SYR
2 stops45h 20m
Allegiant Air
Sun 7/1210:38 am
SYR
- SGF
1 stop22h 23m
Allegiant Air
Deal found 4/28![Allegiant Air logo]()
$561
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:04 pm
STL
- SYR
1 stop3h 54m
Delta
Tue 8/46:54 pm
SYR
- STL
1 stop5h 59m
Delta
Deal found 4/26![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:25 pm
STL
- SYR
1 stop7h 03m
Delta
Mon 6/86:05 am
SYR
- STL
1 stop7h 29m
Delta
Deal found 4/30![Delta logo]()
$300
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
STL
- SYR
2 stops7h 15m
United Airlines
Tue 6/96:00 am
SYR
- STL
2 stops7h 11m
United Airlines
Deal found 4/30![United Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:17 pm
SGF
- SYR
1 stop6h 22m
American Airlines
Sat 5/165:40 am
SYR
- SGF
1 stop5h 11m
American Airlines
Deal found 4/27![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:22 pm
MCI
- SYR
1 stop4h 24m
United Airlines
Sat 5/235:49 pm
SYR
- MCI
1 stop4h 58m
United Airlines
Deal found 4/30![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:37 pm
MCI
- SYR
1 stop5h 06m
Delta
Tue 6/166:54 pm
SYR
- MCI
1 stop6h 05m
Delta
Deal found 4/28![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:16 am
COU
- SYR
1 stop7h 18m
American Airlines
Sun 5/175:40 am
SYR
- COU
1 stop5h 03m
American Airlines
Deal found 4/27![American Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:44 pm
MCI
- SYR
1 stop4h 13m
Delta
Sun 6/146:05 am
SYR
- MCI
1 stop7h 10m
Delta
Deal found 4/29![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 am
STL
- SYR
2 stops7h 09m
United Airlines
Sun 9/65:44 pm
SYR
- STL
1 stop4h 38m
United Airlines
Deal found 4/29![United Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:42 pm
MCI
- SYR
1 stop4h 31m
Delta
Sat 7/116:00 am
SYR
- MCI
1 stop5h 12m
Delta
Deal found 4/26![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:00 am
STL
- SYR
2 stops7h 15m
United Airlines
Thu 7/26:15 am
SYR
- STL
1 stop6h 56m
United Airlines
Deal found 4/26![United Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:10 am
SGF
- SYR
1 stop15h 49m
American Airlines
Tue 6/96:00 am
SYR
- SGF
1 stop14h 09m
American Airlines
Deal found 4/26![American Airlines logo]()
$507
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
MCI
- SYR
2 stops7h 15m
United Airlines
Tue 8/45:49 pm
SYR
- MCI
1 stop6h 29m
United Airlines
Deal found 4/27![United Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:00 am
STL
- SYR
1 stop27h 09m
Delta
Tue 8/186:50 pm
SYR
- STL
1 stop5h 47m
Delta
Deal found 4/26![Delta logo]()
$413
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:11 pm
SGF
- SYR
1 stop4h 54m
American Airlines
Sun 7/128:00 am
SYR
- SGF
1 stop5h 52m
American Airlines
Deal found 4/26![American Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:13 pm
STL
- SYR
1 stop6h 56m
United Airlines
Tue 8/46:00 am
SYR
- STL
2 stops7h 11m
United Airlines
Deal found 4/27![United Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:35 pm
MCI
- SYR
1 stop5h 23m
Delta
Sat 8/16:12 am
SYR
- MCI
1 stop4h 32m
Delta
Deal found 4/25![Delta logo]()
$429
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:30 am
STL
- SYR
1 stop5h 31m
Delta
Sun 7/196:54 pm
SYR
- STL
1 stop5h 59m
Delta
Deal found 4/27![Delta logo]()
$444
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:39 am
MCI
- SYR
1 stop8h 09m
Delta
Tue 7/286:12 am
SYR
- MCI
1 stop4h 32m
Delta
Deal found 4/27![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:10 pm
COU
- SYR
2 stops7h 20m
United Airlines
Mon 5/186:15 am
SYR
- COU
1 stop5h 40m
United Airlines
Deal found 4/28![United Airlines logo]()
$544
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:40 pm
MCI
- SYR
1 stop4h 18m
Delta
Mon 7/137:30 am
SYR
- MCI
1 stop5h 16m
Delta
Deal found 4/26![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:35 pm
SGF
- SYR
1 stop25h 44m
United Airlines
Mon 5/256:15 am
SYR
- SGF
1 stop5h 27m
United Airlines
Deal found 4/28![United Airlines logo]()
$603
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:40 am
SGF
- SYR
2 stops10h 16m
Delta
Tue 9/16:00 am
SYR
- SGF
2 stops9h 45m
Delta
Deal found 4/29![Delta logo]()
$489
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:57 pm
JLN
- SYR
1 stop8h 47m
United Airlines
Mon 5/256:15 am
SYR
- JLN
1 stop8h 07m
United Airlines
Deal found 4/28![United Airlines logo]()
$650
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:07 pm
SGF
- SYR
2 stops11h 21m
Delta
Tue 6/96:00 am
SYR
- SGF
2 stops13h 12m
Delta
Deal found 4/26![Delta logo]()
$717
Last-minute flights from Missouri to SyracuseDiscover last-minute flight deals from Missouri to Syracuse. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Syracuse. Data last updated May 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:17 pm
SGF
- SYR
1 stop6h 22m
American Airlines
Sat 5/165:40 am
SYR
- SGF
1 stop5h 11m
American Airlines
Deal found 4/27![American Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:04 pm
STL
- SYR
1 stop4h 45m
Delta
Sun 5/176:00 am
SYR
- STL
1 stop4h 44m
Delta
Deal found 4/27![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:30 am
MCI
- SYR
1 stop4h 54m
Delta
Sat 5/236:20 am
SYR
- MCI
1 stop4h 26m
Delta
Deal found 4/29![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:22 pm
MCI
- SYR
2 stops7h 08m
United Airlines
Sat 5/236:15 am
SYR
- MCI
1 stop5h 14m
United Airlines
Deal found 4/30![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:51 am
STL
- SYR
1 stop4h 09m
American Airlines
Sun 5/247:30 pm
SYR
- STL
1 stop5h 14m
American Airlines
Deal found 4/26![American Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:19 pm
STL
- SYR
1 stop16h 12m
Multiple Airlines
Mon 6/110:21 am
SYR
- STL
2 stops32h 12m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:27 pm
STL
- SYR
2 stops43h 17m
Multiple Airlines
Mon 6/110:21 am
SYR
- STL
1 stop14h 36m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:45 am
STL
- SYR
1 stop4h 39m
Delta
Wed 6/36:00 am
SYR
- STL
1 stop7h 20m
Delta
Deal found 4/27![Delta logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- SYR
2 stops47h 03m
Multiple Airlines
Mon 6/110:21 am
SYR
- STL
1 stop14h 36m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:19 am
STL
- SYR
1 stop4h 56m
Delta
Tue 6/25:40 pm
SYR
- STL
1 stop4h 29m
Delta
Deal found 4/27![Delta logo]()
$310
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 pm
STL
- SYR
1 stop5h 07m
American Airlines
Thu 6/48:32 pm
SYR
- STL
1 stop4h 44m
American Airlines
Deal found 4/30![American Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:19 pm
STL
- SYR
1 stop16h 12m
Multiple Airlines
Thu 6/47:26 pm
SYR
- STL
2 stops38h 29m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$316
One-way flights from Missouri to SyracuseSearch for one-way flight options from Missouri to Syracuse. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Missouri to Syracuse. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:40 am
MCI
- SYR
1 stop29h 55m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:16 pm
MCI
- SYR
2 stops20h 43m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/43:34 pm
STL
- SYR
2 stops50h 02m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:16 pm
MCI
- SYR
2 stops20h 43m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:40 am
MCI
- SYR
1 stop29h 55m
Allegiant Air
Deal found 4/26![Allegiant Air logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:35 am
MCI
- SYR
1 stop21h 56m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:34 pm
MCI
- SYR
3 stops51h 02m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:33 pm
STL
- SYR
2 stops15h 59m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:23 pm
SGF
- SYR
2 stops39h 25m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:10 pm
STL
- SYR
1 stop3h 47m
Delta
Deal found 4/29![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/49:08 am
STL
- SYR
1 stop6h 35m
American Airlines
Deal found 4/27![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
STL
- SYR
2 stops7h 15m
United Airlines
Deal found 4/27![United Airlines logo]()
$284
Find flight deals from Missouri to Syracuse
Keep the following information in mind while searching for Missouri to Syracuse flight deals. Data was last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $277 (Kiwi.com) |
One-way from | $152 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $401 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Missouri to Syracuse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSyracuse
STL - SYR
STLSYR
Lambert-St Louis
Tue 6/2
10:49 am-6:54 pm
1 stop7h 05m
Syracuse Hancock Intl
Tue 6/9
6:00 am-11:49 am
1 stop6h 49m
$291
St. LouisSyracuse
STL - SYR
STLSYR
Lambert-St Louis
Sat 8/1
6:04 pm-10:58 pm
1 stop3h 54m
Syracuse Hancock Intl
Tue 8/4
6:54 pm-11:53 pm
1 stop5h 59m
$291
SpringfieldSyracuse
SGF - SYR
SGFSYR
Springfield-Branson
Wed 8/26
3:01 pm-9:54 pm
1 stop5h 53m
Syracuse Hancock Intl
Tue 9/1
6:02 am-10:03 am
1 stop5h 01m
$300
St. LouisSyracuse
STL - SYR
STLSYR
Lambert-St Louis
Wed 6/3
4:25 pm-12:28 am
1 stop7h 03m
Syracuse Hancock Intl
Mon 6/8
6:05 am-12:34 pm
1 stop7h 29m
$300
St. LouisSyracuse
STL - SYR
STLSYR
Lambert-St Louis
Fri 6/5
1:13 pm-9:19 pm
1 stop7h 06m
Syracuse Hancock Intl
Mon 6/8
5:44 pm-9:16 pm
1 stop4h 32m
$309
Kansas CitySyracuse
MCI - SYR
MCISYR
Kansas City
Tue 6/9
5:37 pm-11:43 pm
1 stop5h 06m
Syracuse Hancock Intl
Tue 6/16
6:54 pm-11:59 pm
1 stop6h 05m
$339
St. LouisSyracuse
STL - SYR
STLSYR
Lambert-St Louis
Wed 6/3
6:00 am-2:15 pm
2 stops7h 15m
Syracuse Hancock Intl
Tue 6/9
6:00 am-12:11 pm
2 stops7h 11m
$346
SpringfieldSyracuse
SGF - SYR
SGFSYR
Springfield-Branson
Tue 5/12
3:17 pm-10:39 pm
1 stop6h 22m
Syracuse Hancock Intl
Sat 5/16
5:40 am-9:51 am
1 stop5h 11m
$347
Quickest round-trip
Kansas CitySyracuse
MCI - SYR
MCISYR
Kansas City
Sat 5/16
3:22 pm-8:46 pm
1 stop4h 24m
Syracuse Hancock Intl
Sat 5/23
5:49 pm-9:47 pm
1 stop4h 58m
$354
St. LouisSyracuse
STL - SYR
STLSYR
Lambert-St Louis
Sun 5/24
4:19 pm-9:31 am
1 stop16h 12m
Syracuse Hancock Intl
Mon 6/1
10:21 am-11:57 pm
1 stop14h 36m
$359
Showing 1-10 of 49 resultsSorted by cheapest first
Best time to book a flight from Missouri to Syracuse
Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.
STL-SYR
SGF-SYR
MCI-SYR
COU-SYR
JLN-SYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Syracuse
USMO-SYR
STL-SYR
SGF-SYR
MCI-SYR
COU-SYR
What is the cheapest month to book a flight from Missouri to Syracuse?
Currently, July is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $155). Flying from Missouri to Syracuse in March is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Syracuse?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Syracuse?
Book flights to Syracuse if you plan to visit one of these locationsEast Syracuse
Liverpool
Waterloo
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Alternative routes for Missouri to Syracuse
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Complete your trip
Complete your trip to Syracuse by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Syracuse by cabin class
Find flights from Missouri to Syracuse, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Syracuse flights
Browse other Missouri and Syracuse flight options. Last updated on May 1, 2026.
Popular flight searches
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Other flights to Syracuse
Explore flights to Syracuse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 1, 2026.
Missouri to Syracuse flights
Consider these flights traveling from Missouri to Syracuse.
Top 3 airlines flying from Missouri to Syracuse
Discover the top 3 airlines that operate flights from Missouri to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$246 | Average$416 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$348 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$354 | FlexibilityNo cancel fee | On-time69% |