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Syracuse

$159+ Cheap flights from Missouri to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SYR
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheap flight deals from Missouri to Syracuse

Keep the following information in mind while searching for Missouri to Syracuse flight deals. Data was last updated July 1, 2025.

Round-trip from

$249
(Delta)

One-way from

$159
(Mytrip)

Popular in

November

Cheapest in

April

Average price

$328
From Missouri to Syracuse Hancock Intl
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One-way flight from Missouri to Syracuse Hancock Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($51 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Missouri to Syracuse

Cheapest flights from Missouri to Syracuse
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/96:40 amSTL - SYR
1 stop4h 12mDelta
Wed 9/175:55 amSYR - STL
1 stop5h 04mDelta
Deal found 7/1$249
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/24:18 pmSGF - SYR
1 stop5h 20mAmerican Airlines
Wed 9/101:55 pmSYR - SGF
1 stop7h 48mAmerican Airlines
Deal found 6/29$251
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/26:02 amSTL - SYR
1 stop4h 16mAmerican Airlines
Sat 9/63:15 pmSYR - STL
2 stops8h 52mAmerican Airlines
Deal found 6/29$254
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/138:30 amMCI - SYR
1 stop6h 44mAmerican Airlines
Sat 8/166:15 amSYR - MCI
1 stop7h 33mAmerican Airlines
Deal found 6/30$259
This Gotogate deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/207:54 pmSTL - SYR
2 stops23h 48mFrontier
Sun 8/249:37 pmSYR - STL
2 stops16h 19mFrontier
Deal found 6/30$350
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/53:36 pmMCI - SYR
1 stop7h 21mDelta
Sat 7/125:50 amSYR - MCI
1 stop5h 57mDelta
Deal found 7/1$362
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:06 amSGF - SYR
2 stops13h 07mUnited Airlines
Tue 11/1811:05 amSYR - SGF
2 stops12h 08mUnited Airlines
Deal found 6/30$371
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amSGF - SYR
2 stops11h 10mDelta
Tue 11/186:00 amSYR - SGF
2 stops9h 50mDelta
Deal found 6/30$375
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/223:25 pmMCI - SYR
1 stop4h 39mUnited Airlines
Sat 11/296:30 amSYR - MCI
1 stop5h 10mUnited Airlines
Deal found 6/30$386
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/296:17 amCOU - SYR
1 stop5h 26mAmerican Airlines
Tue 8/512:07 pmSYR - COU
2 stops9h 38mAmerican Airlines
Deal found 6/29$408
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1511:44 amMCI - SYR
2 stops24h 21mMultiple Airlines
Sat 8/165:40 pmSYR - MCI
3 stops30h 13mMultiple Airlines
Deal found 6/30$409
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:30 pmSTL - SYR
2 stops15h 13mUnited Airlines
Wed 9/1710:52 amSYR - STL
1 stop5h 52mUnited Airlines
Deal found 6/30$412

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Missouri to Syracuse that are best for you.

Fly from

Missouri

Fly to

Syracuse

Route

Depart

Return

Price

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Tue 9/9

6:40 am-11:52 am

1 stop4h 12m

Syracuse Hancock Intl

Wed 9/17

5:55 am-9:59 am

1 stop5h 04m

$249

SpringfieldSyracuse

SGF - SYR

SGFSYR

Springfield-Branson

Tue 9/2

4:18 pm-10:38 pm

1 stop5h 20m

Syracuse Hancock Intl

Wed 9/10

1:55 pm-8:43 pm

1 stop7h 48m

$251

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Tue 9/2

6:02 am-11:18 am

1 stop4h 16m

Syracuse Hancock Intl

Sat 9/6

3:15 pm-11:07 pm

2 stops8h 52m

$254

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Wed 8/13

8:30 am-4:14 pm

1 stop6h 44m

Syracuse Hancock Intl

Sat 8/16

6:15 am-12:48 pm

1 stop7h 33m

$259

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Wed 8/20

7:54 pm-8:42 pm

2 stops23h 48m

Syracuse Hancock Intl

Sun 8/24

9:37 pm-12:56 pm

2 stops16h 19m

$350

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Sat 7/5

3:36 pm-11:57 pm

1 stop7h 21m

Syracuse Hancock Intl

Sat 7/12

5:50 am-10:47 am

1 stop5h 57m

$362

SpringfieldSyracuse

SGF - SYR

SGFSYR

Springfield-Branson

Fri 11/14

9:06 am-11:13 pm

2 stops13h 07m

Syracuse Hancock Intl

Tue 11/18

11:05 am-10:13 pm

2 stops12h 08m

$371

SpringfieldSyracuse

SGF - SYR

SGFSYR

Springfield-Branson

Thu 11/13

6:00 am-6:10 pm

2 stops11h 10m

Syracuse Hancock Intl

Tue 11/18

6:00 am-2:50 pm

2 stops9h 50m

$375

ColumbiaSyracuse

COU - SYR

COUSYR

Columbia Regional

Tue 7/29

6:17 am-12:43 pm

1 stop5h 26m

Syracuse Hancock Intl

Tue 8/5

12:07 pm-8:45 pm

2 stops9h 38m

$408

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Fri 8/15

11:44 am-1:05 pm

2 stops24h 21m

Syracuse Hancock Intl

Sat 8/16

5:40 pm-10:53 pm

3 stops30h 13m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Showing 1-10 of 24 results
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Best time to book a flight from Missouri to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Syracuse

What is the cheapest month to book a flight from Missouri to Syracuse?

Currently, January is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $272). Flying from Missouri to Syracuse in July is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SYR?

Find hourly flight availability from Missouri to Syracuse. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

When flying from Missouri to Syracuse, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Syracuse

Get insights into the airlines that provide service to Syracuse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Syracuse. Reviews last updated July 1, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Missouri to Syracuse to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,974 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Delta
8.0
Very good
7,974 reviews
Delta
8.0
Very good
7,974 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very good
7,974 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,974 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Allegiant Air
7.2
Good
710 reviews
Delta
8.0
Very good
7,974 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Frontier
5.9
Fair
3,289 reviews
Delta
8.0
Very good
7,974 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from Missouri to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Syracuse from Missouri?

    Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Syracuse from Missouri.

  • What are the cheapest airlines to fly from Missouri to Syracuse one-way?

    One-way options have recently been found by users for as low as $173 on Allegiant Air. Other airlines that offer cheap prices include Delta from $176 and Frontier from $186 one-way.

  • What are the most popular routes from Missouri to Syracuse?

    While some choose either Joplin - Syracuse Hancock Intl or Kansas City - Syracuse Hancock Intl, Lambert-St Louis - Syracuse Hancock Intl is the most popular route from Missouri to Syracuse.

  • Can I find deals for flights from Missouri to Syracuse that include hotel bookings?

    Yes. In addition to deals on Missouri to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Syracuse.

  • Can I find deals for business class flights from Missouri to Syracuse?

    Yes. Cheapflights offers flight deals from Missouri to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Syracuse?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $272). Flying from Missouri to Syracuse in July is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Auburn
Liverpool
Cicero
East Syracuse
Waterloo

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Alternative routes for Missouri to Syracuse

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Top 3 airlines flying from Missouri to Syracuse

Discover the top 3 airlines that operate flights from Missouri to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$379FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$347FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$442FlexibilityNo cancel feeOn-time69%

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