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Missouri

$64+ Cheap flights from Durham, NC to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Durham to Missouri

Keep the following information in mind while searching for Durham to Missouri flight deals. Data was last updated September 16, 2025.

Round-trip from

$180
(Kiwi.com)

One-way from

$64
(Trip.com)

Popular in

January

Cheapest in

July

Average price

$266
From Durham to Missouri
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One-way flight from Durham to Missouri
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Highest demand for flights based on searches. 24% potential increase in price ($110 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Durham to Missouri

Cheapest flights from Durham to Missouri
Explore the most affordable flight options available from Durham to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/42:54 pmRDU - MCI
2 stops44h 23mFrontier
Sun 11/911:12 amMCI - RDU
1 stop5h 50mFrontier
Deal found 9/14$180
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2212:30 pmRDU - MCI
1 stop23h 12mFrontier
Sun 10/2611:37 amMCI - RDU
1 stop10h 23mFrontier
Deal found 9/14$182
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/36:10 amRDU - MCI
1 stop5h 07mFrontier
Thu 11/611:12 amMCI - RDU
1 stop5h 50mFrontier
Deal found 9/14$183
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:15 amRDU - MCI
1 stop5h 27mFrontier
Mon 10/2011:37 amMCI - RDU
1 stop10h 22mFrontier
Deal found 9/14$185
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:12 pmRDU - MCI
2 stops17h 05mFrontier
Thu 11/611:12 amMCI - RDU
1 stop5h 50mFrontier
Deal found 9/14$197
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/36:10 amRDU - MCI
1 stop5h 07mFrontier
Fri 11/711:12 amMCI - RDU
1 stop5h 32mFrontier
Deal found 9/14$198
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:20 amRDU - MCI
Nonstop2h 47mDelta
Sat 10/255:55 pmMCI - RDU
Nonstop2h 21mDelta
Deal found 9/13$199
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2212:30 pmRDU - MCI
1 stop23h 12mMultiple Airlines
Wed 11/510:09 amMCI - RDU
1 stop23h 13mMultiple Airlines
Deal found 9/13$201
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/279:09 amRDU - MCI
1 stop8h 07mMultiple Airlines
Fri 10/3111:12 amMCI - RDU
1 stop10h 53mMultiple Airlines
Deal found 9/14$202
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:15 amRDU - MCI
1 stop5h 27mFrontier
Mon 10/2011:37 amMCI - RDU
1 stop10h 22mFrontier
Deal found 9/15$207
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amRDU - MCI
1 stop6h 36mDelta
Mon 10/276:48 pmMCI - RDU
Nonstop2h 26mDelta
Deal found 9/14$209
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:10 amRDU - MCI
1 stop5h 07mFrontier
Thu 11/68:28 pmMCI - RDU
2 stops25h 10mFrontier
Deal found 9/14$212

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Durham to Missouri that are best for you.

Fly from

Durham

Fly to

Missouri

Route

Depart

Return

Price

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Tue 3/3

7:55 am-9:41 am

Nonstop2h 46m

Kansas City

Wed 3/4

6:55 pm-10:19 pm

Nonstop2h 24m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Thu 10/30

7:20 am-9:07 am

Nonstop2h 47m

Kansas City

Sat 11/8

5:55 pm-9:16 pm

Nonstop2h 21m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Wed 10/29

7:20 am-9:07 am

Nonstop2h 47m

Kansas City

Tue 11/11

6:59 pm-10:23 pm

Nonstop2h 24m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Sat 11/1

7:20 am-9:07 am

Nonstop2h 47m

Kansas City

Tue 11/11

6:59 pm-10:23 pm

Nonstop2h 24m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Sat 11/8

7:20 am-9:07 am

Nonstop2h 47m

Kansas City

Tue 11/11

6:59 pm-10:23 pm

Nonstop2h 24m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Wed 10/29

7:20 am-9:07 am

Nonstop2h 47m

Kansas City

Thu 10/30

6:48 pm-10:14 pm

Nonstop2h 26m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Tue 11/4

7:20 am-9:07 am

Nonstop2h 47m

Kansas City

Wed 11/5

6:48 pm-10:14 pm

Nonstop2h 26m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Sat 11/1

7:20 am-9:07 am

Nonstop2h 47m

Kansas City

Mon 11/10

6:59 pm-10:23 pm

Nonstop2h 24m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Sat 10/25

7:20 am-9:07 am

Nonstop2h 47m

Kansas City

Tue 10/28

5:55 am-11:32 am

1 stop4h 37m

$209

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Tue 11/11

5:30 am-9:52 am

1 stop5h 22m

Kansas City

Mon 11/17

6:59 pm-10:23 pm

Nonstop2h 24m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 58 results
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Best time to book a flight from Durham to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Missouri

What is the cheapest month to book a flight from Durham to Missouri?

Currently, August is the cheapest month in which you can book a flight from Durham to Missouri (average of $311). Flying from Durham to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to MO?

Find hourly flight availability from Durham to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Durham to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 16, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Durham to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,957 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,924 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,174 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Durham to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Durham to Missouri flight route?

    Within the past month, 31 users have taken a look at flights from Durham to Missouri.

  • How long is the flight from Durham to Missouri?

    A quick flight from Durham to Missouri can take about 2h 46m. Delta provides one of the quickest options available for as low as $199. There are 902 mi between Durham and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Durham to Missouri?

    When deciding which route to take from Durham to Missouri consider Raleigh-Durham - Kansas City, Raleigh-Durham - Lambert-St Louis or Raleigh-Durham - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Durham to Missouri?

    Looking for the cheapest flight from Durham to Missouri? While on average our users pay $285, our data indicates the cheapest price to be $99. The most popular route (Raleigh-Durham - Kansas City), is priced around $199.

  • Can I find deals for flights from Durham to Missouri that include hotel bookings?

    Yes. In addition to deals on Durham to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Missouri.

  • Can I find deals for business class flights from Durham to Missouri?

    Yes. Cheapflights offers flight deals from Durham to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Durham to Missouri (average of $311). Flying from Durham to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Durham to Missouri

Discover the top 5 airlines that operate flights from Durham to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$130Average$243FlexibilityNo cancel feeOn-time62%
DeltaCheapest$161Average$326FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$178Average$407FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$195Average$380FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$196Average$379FlexibilityNo cancel feeOn-time69%

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