$225+ Cheap flights from Durham, NC to Columbia, MO (COU)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — COU
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Cheapest flights from Durham to ColumbiaExplore the most affordable flight options available from Durham to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Durham to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:43 pm -
1 stop7h 03m
Wed 10/76:00 am -
1 stop6h 18m
Deal found 8/23![American Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:39 pm -
1 stop6h 16m
Sat 10/176:24 pm -
1 stop4h 35m
Deal found 8/25![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:37 pm -
1 stop5h 16m
Tue 10/138:17 am -
1 stop5h 31m
Deal found 8/22![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:05 am -
1 stop5h 34m
Wed 10/76:15 am -
2 stops6h 52m
Deal found 8/23![United Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:05 am -
1 stop5h 34m
Sun 10/46:15 am -
1 stop5h 13m
Deal found 8/21![United Airlines logo]()
$318
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
2 stops9h 38m
Mon 10/263:00 pm -
2 stops7h 50m
Deal found 8/24![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:14 pm -
1 stop6h 05m
Wed 9/98:16 am -
1 stop3h 50m
Deal found 8/21![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:09 pm -
1 stop6h 46m
Wed 9/93:12 pm -
2 stops7h 47m
Deal found 8/21![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:01 am -
1 stop5h 03m
Fri 11/276:28 pm -
1 stop4h 39m
Deal found 8/25![American Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:05 am -
1 stop7h 33m
Sun 10/258:00 am -
1 stop4h 49m
Deal found 8/24![United Airlines logo]()
$388
Best flights from Durham to ColumbiaDiscover carefully curated flight deals from Durham to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Durham to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:02 am -
1 stop4h 46m
Mon 11/96:26 pm -
1 stop4h 27m
Deal found 8/25![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:05 am -
1 stop5h 34m
Wed 10/288:00 am -
2 stops10h 02m
Deal found 8/22![United Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:05 am -
1 stop5h 34m
Sun 10/46:15 am -
1 stop5h 13m
Deal found 8/21![United Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:01 am -
1 stop5h 03m
Fri 11/276:28 pm -
1 stop4h 39m
Deal found 8/24![American Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:00 pm -
2 stops9h 55m
Sun 9/136:15 am -
1 stop5h 18m
Deal found 8/25![United Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
2 stops9h 30m
Wed 9/911:20 am -
2 stops8h 40m
Deal found 8/21![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:05 am -
1 stop7h 33m
Sun 10/258:00 am -
1 stop4h 49m
Deal found 8/24![United Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
2 stops9h 18m
Mon 11/93:00 pm -
1 stop5h 39m
Deal found 8/25![United Airlines logo]()
$394
Last-minute flights from Durham to ColumbiaDiscover last-minute flight deals from Durham to Columbia. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to Columbia. Data last updated August 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:14 pm -
1 stop6h 05m
Wed 9/98:16 am -
1 stop3h 50m
Deal found 8/21![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:09 pm -
1 stop6h 46m
Wed 9/93:12 pm -
2 stops7h 47m
Deal found 8/21![United Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:00 pm -
1 stop6h 34m
Tue 9/156:15 am -
1 stop6h 52m
Deal found 8/22![United Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:43 pm -
1 stop7h 03m
Wed 10/76:00 am -
1 stop6h 18m
Deal found 8/23![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:05 am -
1 stop5h 34m
Wed 10/76:15 am -
2 stops6h 52m
Deal found 8/23![United Airlines logo]()
$314
One-way flights from Durham to ColumbiaSearch for one-way flight options from Durham to Columbia. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Durham to Columbia. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/610:07 pm -
2 stops19h 25m
Deal found 8/25![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:20 am -
2 stops29h 16m
Deal found 8/21![Multiple Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:44 pm -
1 stop5h 24m
Deal found 8/21![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:13 pm -
1 stop8h 40m
Deal found 8/23![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/79:20 am -
2 stops13h 13m
Deal found 8/25![United Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:00 pm -
1 stop5h 52m
Deal found 8/25![United Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/93:22 pm -
3 stops26h 10m
Deal found 8/25![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/103:32 pm -
3 stops26h 55m
Deal found 8/25![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/73:32 pm -
3 stops26h 55m
Deal found 8/25![Multiple Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:04 am -
1 stop6h 09m
Deal found 8/21![American Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:05 am -
2 stops14h 28m
Deal found 8/21![United Airlines logo]()
$424
Find flight deals from Durham to Columbia
Keep the following information in mind while searching for Durham to Columbia flight deals. Data was last updated August 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $308 (American Airlines) |
One-way from | $225 (Kiwi.com) |
Popular in | October |
Cheapest in | February |
Average price | $503 |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Durham to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Thu 11/5
6:02 am-9:48 am
1 stop4h 46m
Columbia Regional
Mon 11/9
6:26 pm-11:53 pm
1 stop4h 27m
$308
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Thu 10/22
6:05 am-10:39 am
1 stop5h 34m
Columbia Regional
Wed 10/28
8:00 am-7:02 pm
2 stops10h 02m
$314
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Fri 10/2
6:05 am-10:39 am
1 stop5h 34m
Columbia Regional
Sun 10/4
6:15 am-12:28 pm
1 stop5h 13m
$318
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Wed 9/9
2:00 pm-10:55 pm
2 stops9h 55m
Columbia Regional
Sun 9/13
6:15 am-12:33 pm
1 stop5h 18m
$344
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Sat 9/5
6:00 am-2:30 pm
2 stops9h 30m
Columbia Regional
Wed 9/9
11:20 am-9:00 pm
2 stops8h 40m
$349
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Tue 11/24
6:01 am-10:04 am
1 stop5h 03m
Columbia Regional
Fri 11/27
6:28 pm-12:07 am
1 stop4h 39m
$353
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Sat 10/17
8:05 am-2:38 pm
1 stop7h 33m
Columbia Regional
Sun 10/25
8:00 am-1:49 pm
1 stop4h 49m
$388
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Thu 11/5
6:00 am-2:18 pm
2 stops9h 18m
Columbia Regional
Mon 11/9
3:00 pm-9:39 pm
1 stop5h 39m
$394
Cheapest one-way
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Fri 10/2
5:44 pm-10:08 pm
1 stop5h 24m
$268
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Wed 10/7
2:13 pm-9:53 pm
1 stop8h 40m
$269
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Durham to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Durham with our price prediction graph.
RDU-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to Columbia
DU8-COU
RDU-COU
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Columbia
Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated August 26, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Durham to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Food
6.7
Overall
7.4
Crew
8.1
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Food
6.7
Overall
7.4
Crew
8.1
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Food
6.7
Overall
7.4
Crew
8.1
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Durham to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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Durham and Columbia flights
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Top 2 airlines flying from Durham to Columbia
Discover the top 2 airlines that operate flights from Durham to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$354 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$298 | Average$403 | FlexibilityNo cancel fee | On-time71% |