$61+ Cheap flights from Durham, NC to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — MCI
Aug 11 — Aug 181
Round-trip
1 adult, Economy
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Cheapest flights from Durham to MissouriExplore the most affordable flight options available from Durham to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 12, 2026.
Explore the most affordable flight options available from Durham to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:11 pm
RDU
- MCI
1 stop13h 30m
Frontier
Mon 8/3111:26 am
MCI
- RDU
1 stop11h 33m
Frontier
Deal found 7/9![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:56 am
RDU
- MCI
1 stop6h 14m
Frontier
Sat 8/86:17 pm
MCI
- RDU
1 stop12h 54m
Frontier
Deal found 7/9![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/112:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Mon 8/36:09 pm
MCI
- RDU
1 stop13h 02m
Frontier
Deal found 7/9![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:01 pm
RDU
- MCI
1 stop25h 09m
Frontier
Mon 8/106:17 pm
MCI
- RDU
1 stop12h 54m
Frontier
Deal found 7/7![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Wed 8/56:17 pm
MCI
- RDU
1 stop12h 44m
Frontier
Deal found 7/8![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:14 pm
RDU
- MCI
1 stop23h 56m
Frontier
Mon 8/106:17 pm
MCI
- RDU
1 stop12h 54m
Frontier
Deal found 7/9![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:14 pm
RDU
- MCI
1 stop23h 56m
Frontier
Wed 8/1911:26 am
MCI
- RDU
1 stop11h 33m
Frontier
Deal found 7/8![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:15 am
RDU
- MCI
1 stop11h 55m
Frontier
Wed 8/126:17 pm
MCI
- RDU
1 stop27h 27m
Frontier
Deal found 7/9![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:35 am
RDU
- MCI
1 stop11h 41m
Frontier
Mon 10/56:11 pm
MCI
- RDU
1 stop19h 56m
Frontier
Deal found 7/10![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:35 am
RDU
- MCI
1 stop11h 41m
Frontier
Wed 10/76:11 pm
MCI
- RDU
1 stop5h 06m
Frontier
Deal found 7/11![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Mon 8/106:17 pm
MCI
- RDU
1 stop12h 54m
Frontier
Deal found 7/11![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Fri 8/146:17 pm
MCI
- RDU
1 stop13h 29m
Frontier
Deal found 7/10![Frontier logo]()
$152
Best flights from Durham to MissouriDiscover carefully curated flight deals from Durham to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 12, 2026.
Discover carefully curated flight deals from Durham to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 12, 2026.
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am
RDU
- MCI
Nonstop2h 52m
Delta
Sun 9/67:15 pm
MCI
- RDU
Nonstop2h 39m
Delta
Deal found 7/11![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:45 am
RDU
- STL
Nonstop2h 10m
Southwest
Tue 10/2010:20 am
STL
- RDU
Nonstop1h 50m
Southwest
Deal found 7/10![Southwest logo]()
$284
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:05 am
RDU
- COU
2 stops8h 33m
United Airlines
Wed 10/76:15 am
COU
- RDU
2 stops9h 50m
United Airlines
Deal found 7/8![United Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:21 pm
RDU
- TBN
1 stop23h 29m
Multiple Airlines
Wed 9/94:20 pm
TBN
- RDU
2 stops14h 10m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:00 am
RDU
- MCI
Nonstop2h 45m
Delta
Mon 10/127:45 pm
MCI
- RDU
Nonstop2h 33m
Delta
Deal found 7/10![Delta logo]()
$281
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am
RDU
- STL
Nonstop2h 10m
Southwest
Tue 10/206:30 pm
STL
- RDU
Nonstop1h 50m
Southwest
Deal found 7/7![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:55 pm
RDU
- SGF
1 stop5h 24m
Delta
Sat 8/226:06 am
SGF
- RDU
1 stop7h 14m
Delta
Deal found 7/10![Delta logo]()
$281
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 am
RDU
- STL
Nonstop2h 10m
Southwest
Thu 11/1210:15 am
STL
- RDU
Nonstop1h 50m
Southwest
Deal found 7/12![Southwest logo]()
$297
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
RDU
- MCI
2 stops9h 07m
United Airlines
Thu 8/136:00 am
MCI
- RDU
2 stops7h 07m
United Airlines
Deal found 7/8![United Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:50 pm
RDU
- STL
1 stop4h 20m
Southwest
Sat 12/58:45 am
STL
- RDU
2 stops9h 45m
Southwest
Deal found 7/7![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:15 pm
RDU
- SGF
1 stop4h 04m
Delta
Mon 8/176:58 pm
SGF
- RDU
1 stop4h 44m
Delta
Deal found 7/8![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:06 am
RDU
- SGF
2 stops11h 49m
United Airlines
Tue 9/16:25 am
SGF
- RDU
1 stop8h 34m
United Airlines
Deal found 7/8![United Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:21 pm
RDU
- TBN
1 stop23h 49m
Multiple Airlines
Thu 9/104:20 pm
TBN
- RDU
2 stops14h 10m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:20 pm
RDU
- STL
Nonstop2h 10m
Southwest
Sat 12/55:05 pm
STL
- RDU
Nonstop1h 45m
Southwest
Deal found 7/9![Southwest logo]()
$306
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 pm
RDU
- STL
1 stop6h 33m
Delta
Mon 11/26:00 pm
STL
- RDU
1 stop4h 42m
Delta
Deal found 7/11![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:25 am
RDU
- SGF
2 stops13h 30m
United Airlines
Wed 9/23:05 pm
SGF
- RDU
1 stop5h 54m
United Airlines
Deal found 7/11![United Airlines logo]()
$366
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:25 am
RDU
- STL
Nonstop2h 05m
Southwest
Mon 8/1710:10 am
STL
- RDU
Nonstop1h 50m
Southwest
Deal found 7/7![Southwest logo]()
$306
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:45 am
RDU
- STL
1 stop5h 11m
Delta
Sat 12/510:45 am
STL
- RDU
1 stop4h 49m
Delta
Deal found 7/9![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:36 am
RDU
- SGF
2 stops9h 19m
United Airlines
Thu 9/249:00 am
SGF
- RDU
1 stop5h 49m
United Airlines
Deal found 7/9![United Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:52 pm
RDU
- TBN
2 stops20h 48m
Multiple Airlines
Mon 8/34:20 pm
TBN
- RDU
1 stop19h 31m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/162:05 pm
RDU
- MCI
Nonstop2h 30m
Southwest
Wed 8/198:20 am
MCI
- RDU
1 stop3h 45m
Southwest
Deal found 7/8![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:15 pm
RDU
- SGF
1 stop5h 06m
Delta
Sat 8/156:06 am
SGF
- RDU
1 stop7h 14m
Delta
Deal found 7/8![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:09 pm
RDU
- COU
1 stop6h 46m
United Airlines
Wed 9/210:55 am
COU
- RDU
1 stop5h 46m
United Airlines
Deal found 7/11![United Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:00 am
RDU
- MCI
Nonstop2h 52m
Delta
Wed 8/197:15 pm
MCI
- RDU
Nonstop2h 39m
Delta
Deal found 7/10![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:25 am
RDU
- JLN
1 stop7h 53m
United Airlines
Wed 9/307:32 am
JLN
- RDU
1 stop7h 31m
United Airlines
Deal found 7/11![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:23 pm
RDU
- JLN
1 stop8h 21m
United Airlines
Mon 8/311:53 pm
JLN
- RDU
1 stop8h 33m
United Airlines
Deal found 7/10![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
RDU
- MCI
Nonstop2h 52m
Delta
Thu 8/135:18 pm
MCI
- RDU
1 stop5h 07m
Delta
Deal found 7/8![Delta logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:36 pm
RDU
- TBN
1 stop23h 14m
Multiple Airlines
Sat 8/1512:40 pm
TBN
- RDU
1 stop22h 56m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$581
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:25 am
RDU
- JLN
1 stop6h 57m
United Airlines
Wed 11/47:02 am
JLN
- RDU
1 stop5h 40m
United Airlines
Deal found 7/9![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:00 am
RDU
- MCI
Nonstop2h 52m
Delta
Sun 8/168:11 am
MCI
- RDU
1 stop6h 52m
Delta
Deal found 7/8![Delta logo]()
$363
Last-minute flights from Durham to MissouriDiscover last-minute flight deals from Durham to Missouri. Data last updated July 12, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to Missouri. Data last updated July 12, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:15 am
RDU
- STL
1 stop27h 42m
Frontier
Sat 8/18:08 pm
STL
- RDU
2 stops11h 03m
Frontier
Deal found 7/11![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/112:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Mon 8/36:09 pm
MCI
- RDU
1 stop13h 02m
Frontier
Deal found 7/9![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Wed 8/56:17 pm
MCI
- RDU
1 stop12h 44m
Frontier
Deal found 7/8![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:01 pm
RDU
- MCI
1 stop25h 09m
Frontier
Mon 8/106:17 pm
MCI
- RDU
1 stop12h 54m
Frontier
Deal found 7/7![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:56 am
RDU
- MCI
1 stop6h 14m
Frontier
Sat 8/86:17 pm
MCI
- RDU
1 stop12h 54m
Frontier
Deal found 7/9![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:14 pm
RDU
- MCI
1 stop23h 56m
Frontier
Mon 8/106:17 pm
MCI
- RDU
1 stop12h 54m
Frontier
Deal found 7/9![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Mon 8/106:17 pm
MCI
- RDU
1 stop12h 54m
Frontier
Deal found 7/11![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Fri 8/146:17 pm
MCI
- RDU
1 stop13h 29m
Frontier
Deal found 7/10![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:15 am
RDU
- MCI
1 stop11h 55m
Frontier
Wed 8/126:17 pm
MCI
- RDU
1 stop27h 27m
Frontier
Deal found 7/9![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:14 pm
RDU
- MCI
1 stop23h 56m
Frontier
Wed 8/1911:26 am
MCI
- RDU
1 stop11h 33m
Frontier
Deal found 7/8![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:11 pm
RDU
- MCI
1 stop13h 30m
Frontier
Mon 8/3111:26 am
MCI
- RDU
1 stop11h 33m
Frontier
Deal found 7/9![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:05 am
RDU
- MCI
1 stop5h 36m
Frontier
Fri 9/411:26 am
MCI
- RDU
1 stop11h 33m
Frontier
Deal found 7/10![Frontier logo]()
$154
One-way flights from Durham to MissouriSearch for one-way flight options from Durham to Missouri. Find affordable one-way fares based on user searches. Data last updated July 12, 2026.
Search for one-way flight options from Durham to Missouri. Find affordable one-way fares based on user searches. Data last updated July 12, 2026.
This Trip.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:15 am
RDU
- STL
1 stop12h 22m
Frontier
Deal found 7/8![Frontier logo]()
$61
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:11 pm
RDU
- MCI
1 stop20h 05m
Frontier
Deal found 7/9![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:14 pm
RDU
- STL
1 stop15h 43m
Frontier
Deal found 7/9![Frontier logo]()
$63
This Trip.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:05 am
RDU
- MCI
1 stop11h 00m
Frontier
Deal found 7/8![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:35 am
RDU
- STL
1 stop28h 05m
Frontier
Deal found 7/9![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:05 am
RDU
- MCI
1 stop11h 00m
Frontier
Deal found 7/8![Frontier logo]()
$65
This Trip.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:04 pm
RDU
- MCI
1 stop6h 06m
Frontier
Deal found 7/7![Frontier logo]()
$71
This Trip.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:20 pm
RDU
- STL
1 stop18h 20m
Frontier
Deal found 7/10![Frontier logo]()
$71
This Trip.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:15 am
RDU
- MCI
1 stop11h 55m
Frontier
Deal found 7/11![Frontier logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:14 pm
RDU
- MCI
1 stop23h 56m
Frontier
Deal found 7/7![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:20 pm
RDU
- STL
1 stop18h 20m
Frontier
Deal found 7/11![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:14 pm
RDU
- MCI
1 stop23h 56m
Frontier
Deal found 7/7![Frontier logo]()
$74
Find flight deals from Durham to Missouri
Keep the following information in mind while searching for Durham to Missouri flight deals. Data was last updated July 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $121 (Kiwi.com) |
One-way from | $61 (Trip.com) |
Popular in | September |
Cheapest in | October |
Average price | $412 |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
Use the filters below to find and compare flights from Durham to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighKansas City
RDU - MCI
RDUMCI
Raleigh-Durham
Sat 9/5
8:00 am-9:52 am
Nonstop2h 52m
Kansas City
Sun 9/6
7:15 pm-10:54 pm
Nonstop2h 39m
$273
RaleighKansas City
RDU - MCI
RDUMCI
Raleigh-Durham
Fri 10/9
9:00 am-10:45 am
Nonstop2h 45m
Kansas City
Mon 10/12
7:45 pm-11:18 pm
Nonstop2h 33m
$281
RaleighSpringfield
RDU - SGF
RDUSGF
Raleigh-Durham
Sat 8/15
4:55 pm-9:19 pm
1 stop5h 24m
Springfield-Branson
Sat 8/22
6:06 am-2:20 pm
1 stop7h 14m
$281
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Sat 10/17
11:45 am-12:55 pm
Nonstop2h 10m
Lambert-St Louis
Tue 10/20
10:20 am-1:10 pm
Nonstop1h 50m
$284
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Thu 10/15
6:00 am-7:10 am
Nonstop2h 10m
Lambert-St Louis
Tue 10/20
6:30 pm-9:20 pm
Nonstop1h 50m
$284
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Wed 11/11
6:05 am-7:15 am
Nonstop2h 10m
Lambert-St Louis
Thu 11/12
10:15 am-1:05 pm
Nonstop1h 50m
$297
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Wed 12/2
1:50 pm-5:10 pm
1 stop4h 20m
Lambert-St Louis
Sat 12/5
8:45 am-7:30 pm
2 stops9h 45m
$297
RaleighSpringfield
RDU - SGF
RDUSGF
Raleigh-Durham
Sat 8/15
6:15 pm-9:19 pm
1 stop4h 04m
Springfield-Branson
Mon 8/17
6:58 pm-12:42 am
1 stop4h 44m
$305
Quickest round-trip
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Thu 12/3
6:20 pm-7:30 pm
Nonstop2h 10m
Lambert-St Louis
Sat 12/5
5:05 pm-7:50 pm
Nonstop1h 45m
$306
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Sat 8/15
8:25 am-9:30 am
Nonstop2h 05m
Lambert-St Louis
Mon 8/17
10:10 am-1:00 pm
Nonstop1h 50m
$306
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Durham to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Durham with our price prediction graph.
RDU-MCI
RDU-STL
RDU-COU
RDU-TBN
RDU-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to Missouri
DU8-USMO
RDU-MCI
RDU-STL
RDU-COU
RDU-TBN
What is the cheapest time of day to fly from DU8 to MO?
Find hourly flight availability from Durham to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 12, 2026.
One of the essential ways to save on airfare from Durham to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 32% on airfare.
Weekly flight availability from Durham to Missouri
Explore weekly flight availability from Durham to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 12, 2026.
The most flights from DU8 to USMO are scheduled on a Saturday (3 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Durham to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 12, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Durham to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Durham to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Durham to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Durham to Missouri by cabin class
Find flights from Durham to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and Missouri flights
Browse other Durham and Missouri flight options. Last updated on July 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Durham after your stay in Missouri
Durham to Missouri flights
Consider these flights traveling from Durham to Missouri.
Top 5 airlines flying from Durham to Missouri
Discover the top 5 airlines that operate flights from Durham to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$124 | Average$241 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$180 | Average$383 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$187 | Average$342 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$392 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$420 | FlexibilityNo cancel fee | On-time63% |