How popular is this Durham to Missouri flight route?

Within the past month, 13 users have taken a look at flights from Durham to Missouri.

What are the cheapest airlines to fly from Durham to Missouri one-way?

To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $56. American Airlines flights start at $127 while deals on Southwest start at $139 one-way.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular routes from Durham to Missouri?

When deciding which route to take from Durham to Missouri consider Raleigh-Durham - Kansas City, Raleigh-Durham - Lambert-St Louis or Raleigh-Durham - Springfield-Branson as they are the most popular.

What are the cheapest flights from Durham to Missouri?

Looking for the cheapest flight from Durham to Missouri? While on average our users pay $377, our data indicates the cheapest price to be $152. The most popular route (Raleigh-Durham - Kansas City), is priced around $269.

What are the most popular airlines that fly from Durham to Missouri?

Before booking your flight from Durham to Missouri check out the most popular airlines for this route: Southwest, Delta or American Airlines.

Can I find deals for flights from Durham to Missouri that include hotel bookings?

Yes. In addition to deals on Durham to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Durham to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Missouri.

Can I find deals for business class flights from Durham to Missouri?

Yes. Cheapflights offers flight deals from Durham to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Cheap Flights from Durham to Missouri

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Find flight deals from Durham to Missouri

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Popular in	July
Cheapest in	January
Average price	$433

Provider with most accurate pricing for Raleigh-Durham-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Raleigh-Durham-Lambert-St Louis flights.

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Highest demand for flights based on searches. 11% potential increase in price ($54 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in October 2026

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Cheapflights Insights

Everything you need to know about your flight from Durham to Missouri

What is the cheapest time of day to fly from DU8 to MO?

One of the essential ways to save on airfare from Durham to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 30% on airfare.

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Durham to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,217 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Southwest

7.9

Good

4,217 reviews

Southwest

7.9

Good

4,217 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Delta

7.8

Good

8,691 reviews

Southwest

7.9

Good

4,217 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

United Airlines

7.3

Good

10,454 reviews

Southwest

7.9

Good

4,217 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

American Airlines

7.0

Good

12,209 reviews

Southwest

7.9

Good

4,217 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Frontier

5.5

Fair

2,515 reviews

Southwest

7.9

Good

4,217 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

How popular is this Durham to Missouri flight route?
Within the past month, 13 users have taken a look at flights from Durham to Missouri.
What are the cheapest airlines to fly from Durham to Missouri one-way?
To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $56. American Airlines flights start at $127 while deals on Southwest start at $139 one-way.
What are the most popular routes from Durham to Missouri?
When deciding which route to take from Durham to Missouri consider Raleigh-Durham - Kansas City, Raleigh-Durham - Lambert-St Louis or Raleigh-Durham - Springfield-Branson as they are the most popular.
What are the cheapest flights from Durham to Missouri?
Looking for the cheapest flight from Durham to Missouri? While on average our users pay $377, our data indicates the cheapest price to be $152. The most popular route (Raleigh-Durham - Kansas City), is priced around $269.
Can I find deals for flights from Durham to Missouri that include hotel bookings?
Yes. In addition to deals on Durham to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Durham to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Missouri.
Can I find deals for business class flights from Durham to Missouri?
Yes. Cheapflights offers flight deals from Durham to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 5 airlines flying from Durham to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$122	Average$240	FlexibilityNo cancel fee	On-time62%
United Airlines	Cheapest$180	Average$400	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$209	Average$375	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$230	Average$422	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$278	Average$443	FlexibilityNo cancel fee	On-time63%

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Cheap flights from Durham, NC to Missouri

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3. Compare prices and book

Find flight deals from Durham to Missouri

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Cheapflights Insights

What is the cheapest time of day to fly from DU8 to MO?

One of the essential ways to save on airfare from Durham to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 30% on airfare.

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Durham to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

How popular is this Durham to Missouri flight route?

What are the cheapest airlines to fly from Durham to Missouri one-way?

What are the most popular routes from Durham to Missouri?

What are the cheapest flights from Durham to Missouri?

Can I find deals for flights from Durham to Missouri that include hotel bookings?

How can I find direct flights from Durham to Missouri?

Can I find deals for business class flights from Durham to Missouri?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Durham to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Durham to Missouri by cabin class

Find flights from Durham to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Durham and Missouri flights

Browse other Durham and Missouri flight options. Last updated on October 30, 2026.

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Top 5 airlines flying from Durham to Missouri

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